International Journal of Dentistry and Oral Science
Curcumin is the main phytochemical present in the rhizome curcuma longa Linn. Inspite of its ther... more Curcumin is the main phytochemical present in the rhizome curcuma longa Linn. Inspite of its therapeutic efficacy, poor bioavailability due to low absorption, rapid metabolism and elimination deters its beneficial action. Efficient drug delivery system for curcumin is warranted which is achieved by nanoparticle synthesis. This research aimed to prepare and characterise curcumin mediated silver nanoparticles and to evaluate its antibacterial activity against oral pathogens. Biosynthesis of Curcumin mediated silver nanoparticles were achieved when curcumin reduced silver nitrate to silver atom. Characterisation were done by UV-visible absorption spectroscopy (UV-Vis) and Transmission electron microscopy (TEM). Evaluation of antibacterial activity against oral pathogens were performed in Staphylococcus aureus, Streptococcus mutans (Gram positive bacteria), E. coli, Enterococcus sp (Gram negative bacteria). On visual observation, colour change from initial yellow solution to dark brown within 1 hour of reaction time, absorbance peak at 430 nm ascertained curcumin mediated silver nanoparticles synthesis. Curcumin had reducing and capping action. TEM revealed spherical and triangular structure with diameter ranging from 5-70 nm. They showed superior antibacterial activity against oral pathogens such as as S. mutans, moderate activity against S. aureus, E. coli and Enterococcus sp in concentration of 50-μg mL-1hence proving its effective broad spectrum antibacterial activity which can be applied in various oral mucosal lesions with infectious disease with minimal side effects.
453-460<span style="font-size:11.0pt;mso-bidi-font-size: 10.0pt;font-family:" times=... more 453-460<span style="font-size:11.0pt;mso-bidi-font-size: 10.0pt;font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa"="" lang="EN-US">There are distinct biological and gender related differences between man and woman. Because of their special reproductive role, women are at risk of some distinctly gender related disorders. A survey of ethnomedicinal plants used in the rural areas of Kerala gave valuable ethnomedico-botanical information regarding plants used for menstrual disorders. The present study enumerates 19 plant species against Menorrhagia, 26 plant species against Dysmenorrhoea, 25 plant species against Oligomenorrhoea, 5 plant species against Hypomenorrhoea, 4 plant species for Amenorrhoea and 18 plant species which can be included in food during menstrual cycle.</span
International Journal of Dentistry and Oral Science
Objective: This article aimed to green synthesize and characterize turmeric mediated gold nanopar... more Objective: This article aimed to green synthesize and characterize turmeric mediated gold nanoparticles (TuAuNP) and to evaluate its antioxidant, anti-inflammatory, antibacterial activity against oral pathogens for its application in oral mucositis. Materials and Method: Aqueous extract of turmeric powder were used to reduce, stabilize and capgold nanoparticle (AuNP). Reduction of Au3+ to Au NPs were initially observed by colour change from yellow solution to red violet colour within 15 minutes. TuAuNP were analytically characterised by UV-visible spectrophotometer (UV-Vis), Transmission Electron Microscopy (TEM), X-Ray Diffraction Assay (XRD), Fourier Transform Infra Red Analysis (FTIR) and evaluated its antioxidant, anti-inflammatory, antibacterial activity against oral pathogens. Results: Surface Plasmon Resonance bandwith an absorption peak at around 540 nm preliminarily confirmed TuAuNP synthesis. TEM Analysis showed spherical shaped, smooth edged, size ranged of 5-15 nm. XRD analysis revealedface centered cubic crystallinity with intense sharp peaks at 38°, 44°, 64° and 77°. FTIR showed peaks of the functional groups of different phytochemicals of the rhizome extract involved as reducing and capping agent. TuAuNp exhibited 83% highest scavenging ability of DPPH radical at concentration of 50 μg/mL. TuAuNP showed 89.5% of maximum anti-inflammatory activity at 50μg/mL than standard drug diclofenac. TuAuNP exhibited good antibacterial activity against Streptococcusmutans, Klebsiella Pneumoniae at 100µg/mL, Pseudomonasaeruginosa, Enterococcifaecalis at 50µg/mL, moderate antibacterial activity against Staphylococci aureus at 50µg/mL. Conclusion: Turmeric mediated green synthesis of gold nanoparticles exhibited good antioxidant, anti-inflammatory, broad spectrumantibacterial activities against oral pathogens that could be applied in treating oral mucositisas oral insitu or transmucosal preparations.
2018 Second International Conference on Inventive Communication and Computational Technologies (ICICCT), 2018
The goal of our project is to design a system which controls the traffic signal based on vehicle ... more The goal of our project is to design a system which controls the traffic signal based on vehicle density and sound sensing. In daily routine we come across many control signals with fixed time and that causes pedestrians to wait for the traffic signal even though there is no traffic on the other sides and traffic light control time extend on the non-peak hours. It may cause high fuel consumption, long time duration for people and emergency vehicle control is difficult. In order to reduce these problems, we are using density sensor for measuring density of the vehicles and sound sensors to detect the sound signals of such vehicles. All these sensors are interfaced to the PIC micro controller to collect the data and provide priority to the congested lane.
The electrical resistivity method is widely used in groundwater exploration studies. The method i... more The electrical resistivity method is widely used in groundwater exploration studies. The method is particularly well suited to carry out groundwater studies in hard-rock terrains. The popular Schlumberger method of electrode con®guration was applied in the study area. In all, 112 vertical electrical soundings (VESs) were carried out at different locations in the study area. VES interpretations were used to generate a top-layer contour map and a depth-to-basement map. Finally, a groundwater quality/potential map for the study area was generated using the depth-to-bedrock map, a water-level¯uctuation map, and the second-layer thickness. Furthermore, this groundwater potential map was classi®ed into three sectors, i.e. poor, moderate and good zones with respect to the prospects of ®nding groundwater in the study area. This map has a practical value, as it provides guidance to farmers in selecting favourable well sites, thereby avoiding unnecessary ®nancial losses.
Hydrogeomorphology and lineament studies have been completed by using satellite data for the Page... more Hydrogeomorphology and lineament studies have been completed by using satellite data for the Pageru river basin, Cuddapah district, Andhra Pradesh, India through visual interpretation of IRS-1B-LISS II FCC (57J/6, J/7, J/10 and J/11) on a 1:50,000 scale. The area has been visually interpreted to delineate various hydrogeomorphic units and lineaments for the development of groundwater. From these studies, various geomorphic units were classi®ed as favourable, moderately favourable and poor zones of groundwater. The integration of geomorphology and lineament studies reveal that shallow groundwater occurrence is controlled by geomorphological characteristics whereas faults/ fractures control the yield of groundwater at intermediate depths.
International Journal of Dentistry and Oral Science
Curcumin is the main phytochemical present in the rhizome curcuma longa Linn. Inspite of its ther... more Curcumin is the main phytochemical present in the rhizome curcuma longa Linn. Inspite of its therapeutic efficacy, poor bioavailability due to low absorption, rapid metabolism and elimination deters its beneficial action. Efficient drug delivery system for curcumin is warranted which is achieved by nanoparticle synthesis. This research aimed to prepare and characterise curcumin mediated silver nanoparticles and to evaluate its antibacterial activity against oral pathogens. Biosynthesis of Curcumin mediated silver nanoparticles were achieved when curcumin reduced silver nitrate to silver atom. Characterisation were done by UV-visible absorption spectroscopy (UV-Vis) and Transmission electron microscopy (TEM). Evaluation of antibacterial activity against oral pathogens were performed in Staphylococcus aureus, Streptococcus mutans (Gram positive bacteria), E. coli, Enterococcus sp (Gram negative bacteria). On visual observation, colour change from initial yellow solution to dark brown within 1 hour of reaction time, absorbance peak at 430 nm ascertained curcumin mediated silver nanoparticles synthesis. Curcumin had reducing and capping action. TEM revealed spherical and triangular structure with diameter ranging from 5-70 nm. They showed superior antibacterial activity against oral pathogens such as as S. mutans, moderate activity against S. aureus, E. coli and Enterococcus sp in concentration of 50-μg mL-1hence proving its effective broad spectrum antibacterial activity which can be applied in various oral mucosal lesions with infectious disease with minimal side effects.
453-460<span style="font-size:11.0pt;mso-bidi-font-size: 10.0pt;font-family:" times=... more 453-460<span style="font-size:11.0pt;mso-bidi-font-size: 10.0pt;font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa"="" lang="EN-US">There are distinct biological and gender related differences between man and woman. Because of their special reproductive role, women are at risk of some distinctly gender related disorders. A survey of ethnomedicinal plants used in the rural areas of Kerala gave valuable ethnomedico-botanical information regarding plants used for menstrual disorders. The present study enumerates 19 plant species against Menorrhagia, 26 plant species against Dysmenorrhoea, 25 plant species against Oligomenorrhoea, 5 plant species against Hypomenorrhoea, 4 plant species for Amenorrhoea and 18 plant species which can be included in food during menstrual cycle.</span
International Journal of Dentistry and Oral Science
Objective: This article aimed to green synthesize and characterize turmeric mediated gold nanopar... more Objective: This article aimed to green synthesize and characterize turmeric mediated gold nanoparticles (TuAuNP) and to evaluate its antioxidant, anti-inflammatory, antibacterial activity against oral pathogens for its application in oral mucositis. Materials and Method: Aqueous extract of turmeric powder were used to reduce, stabilize and capgold nanoparticle (AuNP). Reduction of Au3+ to Au NPs were initially observed by colour change from yellow solution to red violet colour within 15 minutes. TuAuNP were analytically characterised by UV-visible spectrophotometer (UV-Vis), Transmission Electron Microscopy (TEM), X-Ray Diffraction Assay (XRD), Fourier Transform Infra Red Analysis (FTIR) and evaluated its antioxidant, anti-inflammatory, antibacterial activity against oral pathogens. Results: Surface Plasmon Resonance bandwith an absorption peak at around 540 nm preliminarily confirmed TuAuNP synthesis. TEM Analysis showed spherical shaped, smooth edged, size ranged of 5-15 nm. XRD analysis revealedface centered cubic crystallinity with intense sharp peaks at 38°, 44°, 64° and 77°. FTIR showed peaks of the functional groups of different phytochemicals of the rhizome extract involved as reducing and capping agent. TuAuNp exhibited 83% highest scavenging ability of DPPH radical at concentration of 50 μg/mL. TuAuNP showed 89.5% of maximum anti-inflammatory activity at 50μg/mL than standard drug diclofenac. TuAuNP exhibited good antibacterial activity against Streptococcusmutans, Klebsiella Pneumoniae at 100µg/mL, Pseudomonasaeruginosa, Enterococcifaecalis at 50µg/mL, moderate antibacterial activity against Staphylococci aureus at 50µg/mL. Conclusion: Turmeric mediated green synthesis of gold nanoparticles exhibited good antioxidant, anti-inflammatory, broad spectrumantibacterial activities against oral pathogens that could be applied in treating oral mucositisas oral insitu or transmucosal preparations.
2018 Second International Conference on Inventive Communication and Computational Technologies (ICICCT), 2018
The goal of our project is to design a system which controls the traffic signal based on vehicle ... more The goal of our project is to design a system which controls the traffic signal based on vehicle density and sound sensing. In daily routine we come across many control signals with fixed time and that causes pedestrians to wait for the traffic signal even though there is no traffic on the other sides and traffic light control time extend on the non-peak hours. It may cause high fuel consumption, long time duration for people and emergency vehicle control is difficult. In order to reduce these problems, we are using density sensor for measuring density of the vehicles and sound sensors to detect the sound signals of such vehicles. All these sensors are interfaced to the PIC micro controller to collect the data and provide priority to the congested lane.
The electrical resistivity method is widely used in groundwater exploration studies. The method i... more The electrical resistivity method is widely used in groundwater exploration studies. The method is particularly well suited to carry out groundwater studies in hard-rock terrains. The popular Schlumberger method of electrode con®guration was applied in the study area. In all, 112 vertical electrical soundings (VESs) were carried out at different locations in the study area. VES interpretations were used to generate a top-layer contour map and a depth-to-basement map. Finally, a groundwater quality/potential map for the study area was generated using the depth-to-bedrock map, a water-level¯uctuation map, and the second-layer thickness. Furthermore, this groundwater potential map was classi®ed into three sectors, i.e. poor, moderate and good zones with respect to the prospects of ®nding groundwater in the study area. This map has a practical value, as it provides guidance to farmers in selecting favourable well sites, thereby avoiding unnecessary ®nancial losses.
Hydrogeomorphology and lineament studies have been completed by using satellite data for the Page... more Hydrogeomorphology and lineament studies have been completed by using satellite data for the Pageru river basin, Cuddapah district, Andhra Pradesh, India through visual interpretation of IRS-1B-LISS II FCC (57J/6, J/7, J/10 and J/11) on a 1:50,000 scale. The area has been visually interpreted to delineate various hydrogeomorphic units and lineaments for the development of groundwater. From these studies, various geomorphic units were classi®ed as favourable, moderately favourable and poor zones of groundwater. The integration of geomorphology and lineament studies reveal that shallow groundwater occurrence is controlled by geomorphological characteristics whereas faults/ fractures control the yield of groundwater at intermediate depths.
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