Acquired coagulation factor inhibitors are autoantibodies that mainly inhibit the action of coagu... more Acquired coagulation factor inhibitors are autoantibodies that mainly inhibit the action of coagulation factors, and prompt diagnosis and treatment are important in this situation. Treatment often consists of suppression of hemorrhage, elimination of autoantibodies, and correction of the underlying cause. Therapeutic plasma exchange (TPE) is used as an adjuvant treatment in patients with acquired coagulation factor inhibitors; however, there is no consensus about its clinical significance. Herein, we reported a case of a 70-year-old female patient with acquired coagulation factor inhibitors treated with 13 sessions of TPE after antibiotic treatment. The presence of inhibitors was confirmed by the increased coagulation times without correction in the mixing tests and a factor VIII inhibitor level of 12 Bethesda U/mL. Since the patient could not undergo conventional immunosuppressive therapy because of suspected infective endocarditis and spinal osteomyelitis, only TPE was performed with a successful outcome. To our knowledge, this is the first case where acquired coagulation factor inhibitors were managed by TPE alone. Therefore, TPE might be an effective treatment option in patients with acquired coagulation factor inhibitors when conventional immunosuppressive therapy cannot be applied.
... mimicking angiomyolipoma: A case report Jungsuk An, MD1, Ha Na Kim, MD2, Hyun Yee Cho, MD, Ph... more ... mimicking angiomyolipoma: A case report Jungsuk An, MD1, Ha Na Kim, MD2, Hyun Yee Cho, MD, PhD1, Dong-Hae Chung, MD, PhD1, and Na Rae Kim, MD, PhD1 ... A huge oval mass was found at the left parametrium, and the mass measured 16.0×14.0×12.0 cm. ...
Electrodeposition of ferromagnetic materials on wire produce componenits with a helical easy dire... more Electrodeposition of ferromagnetic materials on wire produce componenits with a helical easy direction of is a suitable way of producing magnetic storage elements. One form magnetizationi has yielded the "bit wire" and the "bit of this element, when placed under suitable torsional strain (i.e., as tube" (Fig. 2). In these devices the helical path results a twistor), has magnetic properties suitable for memory application. s Through research into the electrodeposition process, a new device only from the electrodeposition process. This process is has been developed which requires no external stressing. This device of such a nature that the pitch of the helix can be varied. has been designated as the "bit wire." The materials possess the The bit wires, being the lower coercivity material, are desirable temperature stability usually associated with ferromagmore sensitive to stress than are twistors. This problem netic metals and exhibit a high signal-to-noise ratio. Both linear selection and coincident current memory arrays have has1been so by0 paing the bitgwire m arilo been constructed with bit wire and plated twistors. The switching 0.010-inch to 0.015-inch wire or tubing. The larger characteristics and drive requirements are similar for both materials. diameter of the substrate means that the rod current The significant difference lies in the fabricating technique, since the must be increased for satisfactory coincident current bit wire requires no stressing. Both devices are packaged, since unwriting. This disadvantage may be partially eliminated desired strains can change their properties. This problem has been writing. thi disadvantage mayib tiall eliminat minimized by plating the bit wire material on semirigid wire or by changing the pitch of the h xincrease efcircua tubing. The tubular structure offers other advantages, since addi-flux eficiency at the expense of the axial flux efficiency. tional sense, drive, or inhibit wiring may be threaded through the The use of a tube instead of a wire permits the use of tube. an isolated sense-line. This makes it possible to con
Acquired coagulation factor inhibitors are autoantibodies that mainly inhibit the action of coagu... more Acquired coagulation factor inhibitors are autoantibodies that mainly inhibit the action of coagulation factors, and prompt diagnosis and treatment are important in this situation. Treatment often consists of suppression of hemorrhage, elimination of autoantibodies, and correction of the underlying cause. Therapeutic plasma exchange (TPE) is used as an adjuvant treatment in patients with acquired coagulation factor inhibitors; however, there is no consensus about its clinical significance. Herein, we reported a case of a 70-year-old female patient with acquired coagulation factor inhibitors treated with 13 sessions of TPE after antibiotic treatment. The presence of inhibitors was confirmed by the increased coagulation times without correction in the mixing tests and a factor VIII inhibitor level of 12 Bethesda U/mL. Since the patient could not undergo conventional immunosuppressive therapy because of suspected infective endocarditis and spinal osteomyelitis, only TPE was performed with a successful outcome. To our knowledge, this is the first case where acquired coagulation factor inhibitors were managed by TPE alone. Therefore, TPE might be an effective treatment option in patients with acquired coagulation factor inhibitors when conventional immunosuppressive therapy cannot be applied.
... mimicking angiomyolipoma: A case report Jungsuk An, MD1, Ha Na Kim, MD2, Hyun Yee Cho, MD, Ph... more ... mimicking angiomyolipoma: A case report Jungsuk An, MD1, Ha Na Kim, MD2, Hyun Yee Cho, MD, PhD1, Dong-Hae Chung, MD, PhD1, and Na Rae Kim, MD, PhD1 ... A huge oval mass was found at the left parametrium, and the mass measured 16.0×14.0×12.0 cm. ...
Electrodeposition of ferromagnetic materials on wire produce componenits with a helical easy dire... more Electrodeposition of ferromagnetic materials on wire produce componenits with a helical easy direction of is a suitable way of producing magnetic storage elements. One form magnetizationi has yielded the "bit wire" and the "bit of this element, when placed under suitable torsional strain (i.e., as tube" (Fig. 2). In these devices the helical path results a twistor), has magnetic properties suitable for memory application. s Through research into the electrodeposition process, a new device only from the electrodeposition process. This process is has been developed which requires no external stressing. This device of such a nature that the pitch of the helix can be varied. has been designated as the "bit wire." The materials possess the The bit wires, being the lower coercivity material, are desirable temperature stability usually associated with ferromagmore sensitive to stress than are twistors. This problem netic metals and exhibit a high signal-to-noise ratio. Both linear selection and coincident current memory arrays have has1been so by0 paing the bitgwire m arilo been constructed with bit wire and plated twistors. The switching 0.010-inch to 0.015-inch wire or tubing. The larger characteristics and drive requirements are similar for both materials. diameter of the substrate means that the rod current The significant difference lies in the fabricating technique, since the must be increased for satisfactory coincident current bit wire requires no stressing. Both devices are packaged, since unwriting. This disadvantage may be partially eliminated desired strains can change their properties. This problem has been writing. thi disadvantage mayib tiall eliminat minimized by plating the bit wire material on semirigid wire or by changing the pitch of the h xincrease efcircua tubing. The tubular structure offers other advantages, since addi-flux eficiency at the expense of the axial flux efficiency. tional sense, drive, or inhibit wiring may be threaded through the The use of a tube instead of a wire permits the use of tube. an isolated sense-line. This makes it possible to con
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