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amit shukla

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Papers by amit shukla

Effectivness of an advertising compaign for the 'Dairy Fresh Brand' of ice cream and the phenomenon of cross shopping between multiple brands of icecream marketed by Vadilal Enterprises Limited

Threshold-less mobile-driven handoff method for cellular systems using unlicensed spectrum

Severity of Tip-Out Induced Impacts in Drive Line Systems With Backlash

Journal of Computational and Nonlinear Dynamics, 2010

Numerical simulations are used to study the transient behavior of a four degree-of-freedom, rotat... more Numerical simulations are used to study the transient behavior of a four degree-of-freedom, rotational piecewise linear system. This study focuses on the impact between bodies in a system with backlash as a result of a sudden step input and the associated transient response. The subsequent single sided impacts and double sided impacts are studied as a function of the amplitude of the step input and the size of the backlash. Transitions have been observed between double sided impact regions and single sided impact regions, which agree with earlier findings. However, in this paper a more complete overview of the boundaries is given. The severity of the impacts is quantified with the peak-to-peak acceleration of the impacting bodies. The increase in the size of step input increases the severity of the impacts. However, the increase in backlash size leads to an extremum in impact severity. This is a possible explanation for seeming contradictions in literature.

A study on assessment of symptoms and functionality in DOTS cured patients in two districts of Garhwal, Uttarakhand

Indian Journal of Tuberculosis, 2015

In 2013, an estimated 9.0 million people developed TB and 1.5 million died from the disease. Indi... more In 2013, an estimated 9.0 million people developed TB and 1.5 million died from the disease. India has achieved the target of a case detection rate of 70% and a cure rate of 85% through the nationwide Directly Observed Treatment Short Course (DOTS) strategy. Tuberculosis may generate residual lesions in the course of its pathology, which impair the functionality of the patient even after achieving &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;cure&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot; or &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;treatment completion&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;. To assess the presence of symptoms and functionality of tuberculosis patients who had completed the treatment or had been declared as cured under Revised National Tuberculosis Programme (RNTCP). The present study was a cross sectional study. It was conducted in the two Tuberculosis Units (TUs) of Rudraprayag and Pauri in Garhwal region of Uttarakhand among the people who had completed treatment under DOTS or had been declared as cured under RNTCP in last one year. Even at the completion of the treatment about 37% had cough, 25% had expectoration, 6% had hemoptysis, more than 50% had chest pain and 65% had breathlessness. The mean distance walked by the participants in six minutes was 363.5 ± 58.2 m with a range of 245-490 m. The persistence of symptoms indicate that the functionality of DOTS cured patients remains compromised even after days and months of treatment completion, thereby necessitating measures for the improvement of the overall health of the patients rather than just the microbiological cure.

Classification of Periodic Solutions in a Single-Degree-of-Freedom System With Backlash

Volume 5: 6th International Conference on Multibody Systems, Nonlinear Dynamics, and Control, Parts A, B, and C, 2007

In this paper a single degree-of-freedom system with backlash is studied for its periodic respons... more In this paper a single degree-of-freedom system with backlash is studied for its periodic response. This system is modeled as a piecewise linear system with discontinuity in the net restoring force, caused by additional damping in the contact-zone. The periodic orbits are classified by their number of subspace boundary crossings and Floquet multipliers. For this classification, the known analytical solutions in the different subspaces are used in the multiple shooting algorithm and a continuation method. Some observations are also presented about the qualitative features (such as symmetry, rigid body solutions) exhibited by this class of systems.

Nonlinear Dynamics of Interconnected Structures: An Application to DNA Dynamics

Volume 6: 5th International Conference on Multibody Systems, Nonlinear Dynamics, and Control, Parts A, B, and C, 2005

Nonlinear dynamics of DNA base-pairs is essential in many of the genetic features and functions o... more Nonlinear dynamics of DNA base-pairs is essential in many of the genetic features and functions of the molecule. The motion of the base-pair is influenced by the nonlinear potential between the two nucleotides as well as the adjacent base-pairs. In this paper nonlinear dynamics of the base-pairs is investigated. A single degree-of-freedom model for the base-pair dynamics as proposed by Peyrard-Bishop-Dauxois is analyzed. First a single base-pair dynamics is investigated using perturbation method. Then a three base-pair model is numerically investigated to understand the nonlinear response of the system to a harmonic excitation. Finally, it is also shown that the effect of interconnection can be minimized by selecting the environment surrounding the DNA molecule.Copyright © 2005 by ASME

A relative position based algorithm to find out the longest common subsequence from multiple biological sequences

2010 International Conference on Computer and Communication Technology (ICCCT), 2010

Abstract The LCS problem is to find a subsequence that is common to two or more given sequences a... more

Materialized View Selection for Multi-cube Data Models

Advances in Database Technology — EDBT 2000, 2000

OLAP applications use precomputation of aggregate data to improve query response time. While this... more OLAP applications use precomputation of aggregate data to improve query response time. While this problem has been well-studied in the recent database literature, to our knowledge all previous work has focussed on the special case in which all aggregates are computed from a single cube (in a star schema, this corresponds to there being a single fact table). This is unfortunate, because many real world applications require aggregates over multiple fact tables. In this paper, we attempt to fill this lack of discussion about the issues arising in multi-cube data models by analyzing these issues. Then we examine performance issues by studying the precomputation problem for multi-cube systems. We show that this problem is significantly more complex than the single cube precomputation problem, and that algorithms and cost models developed for single cube precomputation must be extended to deal well with the multi-cube case. Our results from a prototype implementation show that for multi-cube workloads substantial performance improvements can be realized by using the multi-cube algorithms.

<title>Nonlinear dynamics of thin film polyvinylidene fluoride cantilevers</title>

Smart Structures and Materials 2004: Electroactive Polymer Actuators and Devices (EAPAD), 2004

Design and development of electro-active polymeric devices for sensing and actuation requires acc... more Design and development of electro-active polymeric devices for sensing and actuation requires accurate characterization of its nonlinear dynamic behavior and performance characteristics. Thin film cantilevers are being applied for numerous sensor and actuator applications. A nonlinear model of a piezoelectric thin plate cantilever is developed in this work using a two-mode approximation developed by Galerkin's method. This reduced order model is then studied using perturbation method for the nonlinear dynamic response due to a harmonic excitation. The results obtained demonstrate the nonlinear nature of the dynamic behavior of thin plates made of polymer polyvinylidene fluoride. The exhibited nonlinear behavior includes parameter dependent amplitude modulation, nonlinear jump and nonlinear dependence on excitation frequency and excitation amplitude. This study is a step forward in understanding the associated dynamics so as to utilize these geometries in various transducer applications.

Simultaneous optimization and evaluation of multiple dimensional queries

ACM SIGMOD Record, 1998

Database researchers have made significant progress on several research issues related to multidi... more Database researchers have made significant progress on several research issues related to multidimensional data analysis, including the development of fast cubing algorithms, efficient schemes for creating and maintaining precomputed group-bys, and the design of efficient storage structures for multidimensional data. However, to date there has been little or no work on multidimensional query optimization. Recently, Microsoft has proposed “OLE DB for OLAP” as a standard multidimensional interface for databases. OLE DB for OLAP defines Multi-Dimensional Expressions (MDX), which have the interesting and challenging feature of allowing clients to ask several related dimensional queries in a single MDX expression. In this paper, we present three algorithms to optimize multiple related dimensional queries. Two of the algorithms focus on how to generate a global plan from several related local plans. The third algorithm focuses on generating a good global plan without first generating loca...

Classification of Nonlinear Dynamics of Human Posture Using Support Vector Machines

Volume 7A: 9th International Conference on Multibody Systems, Nonlinear Dynamics, and Control, 2013

Human postural control can be modeled as a complex, non-linear multi-sensory and multi actuation ... more Human postural control can be modeled as a complex, non-linear multi-sensory and multi actuation system. Postural control requires a balance between various sensory inputs and the corresponding response in a motor control framework. Various motor control disorders result in a propensity for fall. In this paper, a classification scheme using support vector machines (SVM) is investigated to classify individuals between healthy and those prone to balance disorders including falls. First, a computational model is described to illustrate the proposed approach. It is shown that using SVM, in conjunction with L2 Norm associated with the phase space trajectories, it is possible to classify fallers and non-fallers. This metric can then be utilized for clinical application upon further evaluation. This may benefit clinical evaluation of Parkinson’s subjects by complementing the widely used UPDRS scale.Copyright © 2013 by ASME

Coexistence Empirical Study and Analytical Model for Low-Rate WPAN and IEEE 802.11b

2008 IEEE Wireless Communications and Networking Conference, 2008

Abstract The IEEE 802.11 and Low Rate WPAN (LR-WPAN) wireless networks can provide complimentary... more

Detection of minuscule changes in structures from spectral data

The spectral data ie eigenvalues (natural-frequencies) and eigenvectors (mode-shapes), characteri... more

COPD management costs according to the frequency of COPD exacerbations in UK primary care

Background: The economic burden of chronic obstructive pulmonary disease (COPD) exacerbations is ... more Background: The economic burden of chronic obstructive pulmonary disease (COPD) exacerbations is significant, but the impact of other sources on the overall cost of COPD management is largely unknown. We aimed to estimate overall costs for patients experiencing none, one, or two or more exacerbations per year in the UK. Methods: A retrospective cohort of prevalent COPD patients was identified in the Clinical Practice Research Datalink UK database. Patients with information recorded for at least 12 months before and after cohort entry date were included (first prevalent COPD diagnosis confirmed by spirometry on/after April 1, 2009). Patients were categorized as having none, one, or two or more moderate-to-severe COPD exacerbations in the 12 months after cohort entry and further classified by the Global initiative for chronic Obstructive Lung Disease (GOLD) category of airflow obstruction and the Medical Research Council dyspnea scale. Study outcomes included counts of general practitioner interactions, moderate-severe COPD exacerbations, and non-COPD hospitalizations. Estimated resource use costs were calculated using National Health Service reference costs for 2010-2011. Results: The cohort comprised 58,589 patients (mean age 69.5 years, mean dyspnea grade 2.5, females 46.6%, current smokers 33.1%). The average total annual per patient cost of COPD management, excluding medications, was £2,108 for all patients and £1,523, £2,405, and £3,396 for patients experiencing no, one, or two or more moderate-to-severe exacerbations, respectively. General practitioner interactions contributed most to these annual costs, accounting for £1,062 (69.7%), £1,313 (54.6%), and £1,592 (46.9%) in patients with no, one, or two or more moderateto-severe exacerbations, respectively. Conclusion: Disease management strategies focused on reducing costs in primary care may help reduce total COPD costs significantly.

How to Ensure the Availability of Communication Channel for Event Driven Message in VANET

2014 Fourth International Conference on Communication Systems and Network Technologies, 2014

Mobile ad hoc network (MANET) is a collection of mobile computers or devices that cooperatively c... more Mobile ad hoc network (MANET) is a collection of mobile computers or devices that cooperatively communicate with each other without any pre-established infrastructures such as a centralized access point. There are several issues in VANET. One of them is congestion control. In case of increase in the number of beacon messages, broadcasted by many vehicles, the communication channel will easily be congested. So, to overcome this problem we have proposed an algorithm that increases the availability of communication channel for emergency messages over the beacon messages. Keywords: MANET, VANET, Mobility.

Evaluation and development of therapeutic management of subacute toxicity of Jatropha curcas seed oil in goats

Veterinary World, 2013

The present study was designed to evaluate and develop the therapeutic management for toxicity of... more The present study was designed to evaluate and develop the therapeutic management for toxicity of Jatropha curcas seed oil in goats. Materials and Methods: Sub-acute toxicity of J. curcas seed oil was evaluated by using nine healthy goats, weighing 28-32 kg and 16-18 months old, equally and randomly divided in three groups (n = 3 per group). Adequate measures were taken to minimize pain to the animals. Group I served as control; they did not receive any treatment. The study was conducted by daily oral dosing of J. curcas seed oil @ 1ml / kg body weight followed by the treatment with the therapeutic module comprising of sodium thiosulphate (50mg/ kg bodyweight) and glutathione (0.25 mg/ kg body weight) in group II; whereas, goats in group III were given daily oral dosing of J. curcas seed oil only for 28 days. Hematobiochemical and antioxidative parameters as Lipid Peroxidase (LPO) and Reduced Glutathione (GSH) in erythrocytes were estimated at day 0, 14 and 28 days. Results: Mild to moderate diarrhoea, dullness, depression and letharginess were observed in all animals in group III, whereas, mild clinical signs were observed in treatment group II. A significant (P<0.05) decrease in Hb , PCV, TEC ,TLC , total serum protein , albumin and globulin values were observed in group II and III in comparison to the control group I, however, the group II showed increase in the aforesaid parameters in comparison with without group III indicating the therapeutic efficacy of the therapeutic module. A significant (P<0.05) increase in serum creatinine, serum urea, cholesterol, AST, ALT and ALP were observed in all the groups. Antioxidative parameters in erythrocytes as LPO and GSH increased in group III in comparison to the control and group II. Conclusion: It is concluded from the above study that therapeutic module comprising of sodium thiosulphate (50mg/kg IV) and glutathione (0.25 mg/kg IM) in sub-acute study reduces the toxic effects of J. curcas seed oil as indicated by the improved Hematobiochemical values in the with treatment group II than the without treatment group III.

Control of bifurcations in multidimensional parameter space for servo-hydraulic systems

American Control Conference, 2002

Hydraulic systems offer significant advantages in motion and force control systems from the stand... more Hydraulic systems offer significant advantages in motion and force control systems from the standpoint of high force and power capacities. These drives also have significant nonlinear characteristics. These nonlinear servo-hydraulic systems exhibit loss of stability via bifurcations. Multiple parameter bifurcation theory can be used to map the bifurcation behavior of the servo-hydraulic systems in parametric space. The study of servo-hydraulic

Abscisic acid: one of the factors affecting male sterility in Brassica napus

Physiologia Plantarum, 1994

The possible involvement of abscisic acid (ABA) in the expression of male sterility in a genie ma... more The possible involvement of abscisic acid (ABA) in the expression of male sterility in a genie male steriie (GMS) tnutant of rapeseed (Brassica napus) was investigated. Three experimental approaches were used, namely, in vitro culture of young wild type (WT) floral huds, semi-in vivo culture of WT inflorescences, and an analysis of endogenous ABA levels in various tissues of WT and GMS plants. Abscisic acid alone was inhibitory for the growth of WT floral buds in vitro, but low concenU'ations of ABA (10^* to 10"" M) in combination with 10"^ M benzyladenine, induced near-mature flower bud development. With an increase in ABA concentration, the percentage of near-mature floral buds decreased, and petal and stamen development was affected, Abscisic acid (10"* M and higher concentrations) also affected the flower bud length and pollen viability but not ovular viability, of WT inflorescences cultured in semi-in vivo conditions. The varioti.s GMS tissues, including leaves, flowers and stamens had higher endogenous concentration of ABA in comparison to WT tissues. Also, the stamens had the maximum amount of ABA in comparison tO' other tissues in both genotypes. It is proposed that although ABA is important, it is only one of the plant growth substances involved in tbe expression of male sterility in tbe GMS line of B. napus.

Cytokinins in a genic male sterile line of Brassica napus

Physiologia Plantarum, 1992

Endogenous cytokinin levels were analyzed in four different organs viz., root, stem, leaf and mat... more Endogenous cytokinin levels were analyzed in four different organs viz., root, stem, leaf and mature flower, of the wild type (cv. Westar) and a genie male sterile (GMS) line of Brassica napus. Various cytokinins viz,, bases (Z, DZ), ribosides (ZR, DZR), glucosides (CIGZ + OGZR, OGDZ + OGDZR) and nucleotides (ZNT, DZNT) were quantified using Amaranthus betacyanin bioassay and ELISA. The major cytokinin in all the organs was DZ. In general, leaves had the highest levels of cytokioins as compared to the other organs. Root, stem and mature flowers of the wild type plants had higher levels of cytokinins and their metabolites than the GMS line. However, leaves of the GMS line had greater amount of various cytokinins as compared to the wild type. The major cytokinin quantitatively different between the two lines was DZ. The results suggest the possible involvement of cytokinins in the expression of genie male sterility in Brassica napus.

Resistance to ACCase-Inhibitor Herbicides in Wild Oat: Evidence for Target Site-Based Resistance in Two Biotypes from Canada

Pesticide Biochemistry and Physiology, 1997

Previous results indicated that resistance to acetyl-CoA carboxylase-inhibiting herbicides in the... more Previous results indicated that resistance to acetyl-CoA carboxylase-inhibiting herbicides in the wild oat biotype UM1 was not due to an insensitive form of acetyl-CoA carboxylase (ACCase). However, reanalysis of ACCase extracted under a variety of different buffer conditions indicated that resistance in this biotype is due to an altered form of the enzyme with reduced herbicide sensitivity. Under optimal conditions, ACCase from UM1 was very resistant to sethoxydim (I 50 ϭ 398 M; R/S I 50 ratio ϭ 105) and resistant, although to a lesser extent, to fenoxaprop, diclofop, and tralkoxydim (R/S I 50 ratios ca. 10). Use of the optimum extraction buffer for this biotype did not indicate an ACCase-based resistance mechanism for a second resistant wild oat biotype, UM33. Fenoxaprop and diclofop were metabolized at equal rates in UM33 and a susceptible biotype, indicating that enhanced herbicide metabolism was not responsible for resistance in this biotype. Further modification of the ACCase extraction buffer revealed that resistance in UM33 was also conferred by a target site alteration. These results suggest that certain ingredients in the ACCase extraction buffers can result in the apparent loss of resistance to herbicides and that the optimum buffer may vary for biotypes within a given species. The results also suggest that careful analysis of the sensitivity of ACCase to herbicides is required before concluding that resistance is not based on a target site alteration. ᭧1997 Academic Press

Effectivness of an advertising compaign for the 'Dairy Fresh Brand' of ice cream and the phenomenon of cross shopping between multiple brands of icecream marketed by Vadilal Enterprises Limited

Threshold-less mobile-driven handoff method for cellular systems using unlicensed spectrum

Severity of Tip-Out Induced Impacts in Drive Line Systems With Backlash

Journal of Computational and Nonlinear Dynamics, 2010

Numerical simulations are used to study the transient behavior of a four degree-of-freedom, rotat... more Numerical simulations are used to study the transient behavior of a four degree-of-freedom, rotational piecewise linear system. This study focuses on the impact between bodies in a system with backlash as a result of a sudden step input and the associated transient response. The subsequent single sided impacts and double sided impacts are studied as a function of the amplitude of the step input and the size of the backlash. Transitions have been observed between double sided impact regions and single sided impact regions, which agree with earlier findings. However, in this paper a more complete overview of the boundaries is given. The severity of the impacts is quantified with the peak-to-peak acceleration of the impacting bodies. The increase in the size of step input increases the severity of the impacts. However, the increase in backlash size leads to an extremum in impact severity. This is a possible explanation for seeming contradictions in literature.

A study on assessment of symptoms and functionality in DOTS cured patients in two districts of Garhwal, Uttarakhand

Indian Journal of Tuberculosis, 2015

In 2013, an estimated 9.0 million people developed TB and 1.5 million died from the disease. Indi... more In 2013, an estimated 9.0 million people developed TB and 1.5 million died from the disease. India has achieved the target of a case detection rate of 70% and a cure rate of 85% through the nationwide Directly Observed Treatment Short Course (DOTS) strategy. Tuberculosis may generate residual lesions in the course of its pathology, which impair the functionality of the patient even after achieving &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;cure&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot; or &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;treatment completion&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;. To assess the presence of symptoms and functionality of tuberculosis patients who had completed the treatment or had been declared as cured under Revised National Tuberculosis Programme (RNTCP). The present study was a cross sectional study. It was conducted in the two Tuberculosis Units (TUs) of Rudraprayag and Pauri in Garhwal region of Uttarakhand among the people who had completed treatment under DOTS or had been declared as cured under RNTCP in last one year. Even at the completion of the treatment about 37% had cough, 25% had expectoration, 6% had hemoptysis, more than 50% had chest pain and 65% had breathlessness. The mean distance walked by the participants in six minutes was 363.5 ± 58.2 m with a range of 245-490 m. The persistence of symptoms indicate that the functionality of DOTS cured patients remains compromised even after days and months of treatment completion, thereby necessitating measures for the improvement of the overall health of the patients rather than just the microbiological cure.

Classification of Periodic Solutions in a Single-Degree-of-Freedom System With Backlash

Volume 5: 6th International Conference on Multibody Systems, Nonlinear Dynamics, and Control, Parts A, B, and C, 2007

In this paper a single degree-of-freedom system with backlash is studied for its periodic respons... more In this paper a single degree-of-freedom system with backlash is studied for its periodic response. This system is modeled as a piecewise linear system with discontinuity in the net restoring force, caused by additional damping in the contact-zone. The periodic orbits are classified by their number of subspace boundary crossings and Floquet multipliers. For this classification, the known analytical solutions in the different subspaces are used in the multiple shooting algorithm and a continuation method. Some observations are also presented about the qualitative features (such as symmetry, rigid body solutions) exhibited by this class of systems.

Nonlinear Dynamics of Interconnected Structures: An Application to DNA Dynamics

Volume 6: 5th International Conference on Multibody Systems, Nonlinear Dynamics, and Control, Parts A, B, and C, 2005

Nonlinear dynamics of DNA base-pairs is essential in many of the genetic features and functions o... more Nonlinear dynamics of DNA base-pairs is essential in many of the genetic features and functions of the molecule. The motion of the base-pair is influenced by the nonlinear potential between the two nucleotides as well as the adjacent base-pairs. In this paper nonlinear dynamics of the base-pairs is investigated. A single degree-of-freedom model for the base-pair dynamics as proposed by Peyrard-Bishop-Dauxois is analyzed. First a single base-pair dynamics is investigated using perturbation method. Then a three base-pair model is numerically investigated to understand the nonlinear response of the system to a harmonic excitation. Finally, it is also shown that the effect of interconnection can be minimized by selecting the environment surrounding the DNA molecule.Copyright © 2005 by ASME

A relative position based algorithm to find out the longest common subsequence from multiple biological sequences

2010 International Conference on Computer and Communication Technology (ICCCT), 2010

Abstract The LCS problem is to find a subsequence that is common to two or more given sequences a... more

Materialized View Selection for Multi-cube Data Models

Advances in Database Technology — EDBT 2000, 2000

OLAP applications use precomputation of aggregate data to improve query response time. While this... more OLAP applications use precomputation of aggregate data to improve query response time. While this problem has been well-studied in the recent database literature, to our knowledge all previous work has focussed on the special case in which all aggregates are computed from a single cube (in a star schema, this corresponds to there being a single fact table). This is unfortunate, because many real world applications require aggregates over multiple fact tables. In this paper, we attempt to fill this lack of discussion about the issues arising in multi-cube data models by analyzing these issues. Then we examine performance issues by studying the precomputation problem for multi-cube systems. We show that this problem is significantly more complex than the single cube precomputation problem, and that algorithms and cost models developed for single cube precomputation must be extended to deal well with the multi-cube case. Our results from a prototype implementation show that for multi-cube workloads substantial performance improvements can be realized by using the multi-cube algorithms.

<title>Nonlinear dynamics of thin film polyvinylidene fluoride cantilevers</title>

Smart Structures and Materials 2004: Electroactive Polymer Actuators and Devices (EAPAD), 2004

Design and development of electro-active polymeric devices for sensing and actuation requires acc... more Design and development of electro-active polymeric devices for sensing and actuation requires accurate characterization of its nonlinear dynamic behavior and performance characteristics. Thin film cantilevers are being applied for numerous sensor and actuator applications. A nonlinear model of a piezoelectric thin plate cantilever is developed in this work using a two-mode approximation developed by Galerkin's method. This reduced order model is then studied using perturbation method for the nonlinear dynamic response due to a harmonic excitation. The results obtained demonstrate the nonlinear nature of the dynamic behavior of thin plates made of polymer polyvinylidene fluoride. The exhibited nonlinear behavior includes parameter dependent amplitude modulation, nonlinear jump and nonlinear dependence on excitation frequency and excitation amplitude. This study is a step forward in understanding the associated dynamics so as to utilize these geometries in various transducer applications.

Simultaneous optimization and evaluation of multiple dimensional queries

ACM SIGMOD Record, 1998

Database researchers have made significant progress on several research issues related to multidi... more Database researchers have made significant progress on several research issues related to multidimensional data analysis, including the development of fast cubing algorithms, efficient schemes for creating and maintaining precomputed group-bys, and the design of efficient storage structures for multidimensional data. However, to date there has been little or no work on multidimensional query optimization. Recently, Microsoft has proposed “OLE DB for OLAP” as a standard multidimensional interface for databases. OLE DB for OLAP defines Multi-Dimensional Expressions (MDX), which have the interesting and challenging feature of allowing clients to ask several related dimensional queries in a single MDX expression. In this paper, we present three algorithms to optimize multiple related dimensional queries. Two of the algorithms focus on how to generate a global plan from several related local plans. The third algorithm focuses on generating a good global plan without first generating loca...

Classification of Nonlinear Dynamics of Human Posture Using Support Vector Machines

Volume 7A: 9th International Conference on Multibody Systems, Nonlinear Dynamics, and Control, 2013

Human postural control can be modeled as a complex, non-linear multi-sensory and multi actuation ... more Human postural control can be modeled as a complex, non-linear multi-sensory and multi actuation system. Postural control requires a balance between various sensory inputs and the corresponding response in a motor control framework. Various motor control disorders result in a propensity for fall. In this paper, a classification scheme using support vector machines (SVM) is investigated to classify individuals between healthy and those prone to balance disorders including falls. First, a computational model is described to illustrate the proposed approach. It is shown that using SVM, in conjunction with L2 Norm associated with the phase space trajectories, it is possible to classify fallers and non-fallers. This metric can then be utilized for clinical application upon further evaluation. This may benefit clinical evaluation of Parkinson’s subjects by complementing the widely used UPDRS scale.Copyright © 2013 by ASME

Coexistence Empirical Study and Analytical Model for Low-Rate WPAN and IEEE 802.11b

2008 IEEE Wireless Communications and Networking Conference, 2008

Abstract The IEEE 802.11 and Low Rate WPAN (LR-WPAN) wireless networks can provide complimentary... more

Detection of minuscule changes in structures from spectral data

The spectral data ie eigenvalues (natural-frequencies) and eigenvectors (mode-shapes), characteri... more

COPD management costs according to the frequency of COPD exacerbations in UK primary care

Background: The economic burden of chronic obstructive pulmonary disease (COPD) exacerbations is ... more Background: The economic burden of chronic obstructive pulmonary disease (COPD) exacerbations is significant, but the impact of other sources on the overall cost of COPD management is largely unknown. We aimed to estimate overall costs for patients experiencing none, one, or two or more exacerbations per year in the UK. Methods: A retrospective cohort of prevalent COPD patients was identified in the Clinical Practice Research Datalink UK database. Patients with information recorded for at least 12 months before and after cohort entry date were included (first prevalent COPD diagnosis confirmed by spirometry on/after April 1, 2009). Patients were categorized as having none, one, or two or more moderate-to-severe COPD exacerbations in the 12 months after cohort entry and further classified by the Global initiative for chronic Obstructive Lung Disease (GOLD) category of airflow obstruction and the Medical Research Council dyspnea scale. Study outcomes included counts of general practitioner interactions, moderate-severe COPD exacerbations, and non-COPD hospitalizations. Estimated resource use costs were calculated using National Health Service reference costs for 2010-2011. Results: The cohort comprised 58,589 patients (mean age 69.5 years, mean dyspnea grade 2.5, females 46.6%, current smokers 33.1%). The average total annual per patient cost of COPD management, excluding medications, was £2,108 for all patients and £1,523, £2,405, and £3,396 for patients experiencing no, one, or two or more moderate-to-severe exacerbations, respectively. General practitioner interactions contributed most to these annual costs, accounting for £1,062 (69.7%), £1,313 (54.6%), and £1,592 (46.9%) in patients with no, one, or two or more moderateto-severe exacerbations, respectively. Conclusion: Disease management strategies focused on reducing costs in primary care may help reduce total COPD costs significantly.

How to Ensure the Availability of Communication Channel for Event Driven Message in VANET

2014 Fourth International Conference on Communication Systems and Network Technologies, 2014

Mobile ad hoc network (MANET) is a collection of mobile computers or devices that cooperatively c... more Mobile ad hoc network (MANET) is a collection of mobile computers or devices that cooperatively communicate with each other without any pre-established infrastructures such as a centralized access point. There are several issues in VANET. One of them is congestion control. In case of increase in the number of beacon messages, broadcasted by many vehicles, the communication channel will easily be congested. So, to overcome this problem we have proposed an algorithm that increases the availability of communication channel for emergency messages over the beacon messages. Keywords: MANET, VANET, Mobility.

Evaluation and development of therapeutic management of subacute toxicity of Jatropha curcas seed oil in goats

Veterinary World, 2013

The present study was designed to evaluate and develop the therapeutic management for toxicity of... more The present study was designed to evaluate and develop the therapeutic management for toxicity of Jatropha curcas seed oil in goats. Materials and Methods: Sub-acute toxicity of J. curcas seed oil was evaluated by using nine healthy goats, weighing 28-32 kg and 16-18 months old, equally and randomly divided in three groups (n = 3 per group). Adequate measures were taken to minimize pain to the animals. Group I served as control; they did not receive any treatment. The study was conducted by daily oral dosing of J. curcas seed oil @ 1ml / kg body weight followed by the treatment with the therapeutic module comprising of sodium thiosulphate (50mg/ kg bodyweight) and glutathione (0.25 mg/ kg body weight) in group II; whereas, goats in group III were given daily oral dosing of J. curcas seed oil only for 28 days. Hematobiochemical and antioxidative parameters as Lipid Peroxidase (LPO) and Reduced Glutathione (GSH) in erythrocytes were estimated at day 0, 14 and 28 days. Results: Mild to moderate diarrhoea, dullness, depression and letharginess were observed in all animals in group III, whereas, mild clinical signs were observed in treatment group II. A significant (P<0.05) decrease in Hb , PCV, TEC ,TLC , total serum protein , albumin and globulin values were observed in group II and III in comparison to the control group I, however, the group II showed increase in the aforesaid parameters in comparison with without group III indicating the therapeutic efficacy of the therapeutic module. A significant (P<0.05) increase in serum creatinine, serum urea, cholesterol, AST, ALT and ALP were observed in all the groups. Antioxidative parameters in erythrocytes as LPO and GSH increased in group III in comparison to the control and group II. Conclusion: It is concluded from the above study that therapeutic module comprising of sodium thiosulphate (50mg/kg IV) and glutathione (0.25 mg/kg IM) in sub-acute study reduces the toxic effects of J. curcas seed oil as indicated by the improved Hematobiochemical values in the with treatment group II than the without treatment group III.

Control of bifurcations in multidimensional parameter space for servo-hydraulic systems

American Control Conference, 2002

Hydraulic systems offer significant advantages in motion and force control systems from the stand... more Hydraulic systems offer significant advantages in motion and force control systems from the standpoint of high force and power capacities. These drives also have significant nonlinear characteristics. These nonlinear servo-hydraulic systems exhibit loss of stability via bifurcations. Multiple parameter bifurcation theory can be used to map the bifurcation behavior of the servo-hydraulic systems in parametric space. The study of servo-hydraulic

Abscisic acid: one of the factors affecting male sterility in Brassica napus

Physiologia Plantarum, 1994

The possible involvement of abscisic acid (ABA) in the expression of male sterility in a genie ma... more The possible involvement of abscisic acid (ABA) in the expression of male sterility in a genie male steriie (GMS) tnutant of rapeseed (Brassica napus) was investigated. Three experimental approaches were used, namely, in vitro culture of young wild type (WT) floral huds, semi-in vivo culture of WT inflorescences, and an analysis of endogenous ABA levels in various tissues of WT and GMS plants. Abscisic acid alone was inhibitory for the growth of WT floral buds in vitro, but low concenU'ations of ABA (10^* to 10"" M) in combination with 10"^ M benzyladenine, induced near-mature flower bud development. With an increase in ABA concentration, the percentage of near-mature floral buds decreased, and petal and stamen development was affected, Abscisic acid (10"* M and higher concentrations) also affected the flower bud length and pollen viability but not ovular viability, of WT inflorescences cultured in semi-in vivo conditions. The varioti.s GMS tissues, including leaves, flowers and stamens had higher endogenous concentration of ABA in comparison to WT tissues. Also, the stamens had the maximum amount of ABA in comparison tO' other tissues in both genotypes. It is proposed that although ABA is important, it is only one of the plant growth substances involved in tbe expression of male sterility in tbe GMS line of B. napus.

Cytokinins in a genic male sterile line of Brassica napus

Physiologia Plantarum, 1992

Endogenous cytokinin levels were analyzed in four different organs viz., root, stem, leaf and mat... more Endogenous cytokinin levels were analyzed in four different organs viz., root, stem, leaf and mature flower, of the wild type (cv. Westar) and a genie male sterile (GMS) line of Brassica napus. Various cytokinins viz,, bases (Z, DZ), ribosides (ZR, DZR), glucosides (CIGZ + OGZR, OGDZ + OGDZR) and nucleotides (ZNT, DZNT) were quantified using Amaranthus betacyanin bioassay and ELISA. The major cytokinin in all the organs was DZ. In general, leaves had the highest levels of cytokioins as compared to the other organs. Root, stem and mature flowers of the wild type plants had higher levels of cytokinins and their metabolites than the GMS line. However, leaves of the GMS line had greater amount of various cytokinins as compared to the wild type. The major cytokinin quantitatively different between the two lines was DZ. The results suggest the possible involvement of cytokinins in the expression of genie male sterility in Brassica napus.

Resistance to ACCase-Inhibitor Herbicides in Wild Oat: Evidence for Target Site-Based Resistance in Two Biotypes from Canada

Pesticide Biochemistry and Physiology, 1997

Previous results indicated that resistance to acetyl-CoA carboxylase-inhibiting herbicides in the... more Previous results indicated that resistance to acetyl-CoA carboxylase-inhibiting herbicides in the wild oat biotype UM1 was not due to an insensitive form of acetyl-CoA carboxylase (ACCase). However, reanalysis of ACCase extracted under a variety of different buffer conditions indicated that resistance in this biotype is due to an altered form of the enzyme with reduced herbicide sensitivity. Under optimal conditions, ACCase from UM1 was very resistant to sethoxydim (I 50 ϭ 398 M; R/S I 50 ratio ϭ 105) and resistant, although to a lesser extent, to fenoxaprop, diclofop, and tralkoxydim (R/S I 50 ratios ca. 10). Use of the optimum extraction buffer for this biotype did not indicate an ACCase-based resistance mechanism for a second resistant wild oat biotype, UM33. Fenoxaprop and diclofop were metabolized at equal rates in UM33 and a susceptible biotype, indicating that enhanced herbicide metabolism was not responsible for resistance in this biotype. Further modification of the ACCase extraction buffer revealed that resistance in UM33 was also conferred by a target site alteration. These results suggest that certain ingredients in the ACCase extraction buffers can result in the apparent loss of resistance to herbicides and that the optimum buffer may vary for biotypes within a given species. The results also suggest that careful analysis of the sensitivity of ACCase to herbicides is required before concluding that resistance is not based on a target site alteration. ᭧1997 Academic Press