Upper respiratory tract infections (URTI) are the most common acute illnesses that are often of v... more Upper respiratory tract infections (URTI) are the most common acute illnesses that are often of viral origin. Cough and chest congestion are the common symptoms of this disease. Children are prescribed with drugs that are considered to relive the symptoms of this disease. The topical medications contain vegetable camphor for more than a century that relieve chest congestion and cough caused by URTI. The use of camphor in such products remains questionable especially in children who are more sensitive to its side effects. Herbion "Chest Rub" for children is a camphor-free formulation that contains eucalyptus oil mixture, menthol,turpentine and clove oils and is used to relieve symptoms of URTI.The objective of the present investigationwas to determine the effectiveness of the chest rub inchildren suffering with congestion and cough caused by URTI. The study compared the results of the chest rub applied to a group of infected children with a placebo group. Patients were sele...
Importance: Atrial fibrillation (AF) is the most common rhythm abnormality of the heart and is pr... more Importance: Atrial fibrillation (AF) is the most common rhythm abnormality of the heart and is projected to double between 2010 and 2030. Many patients with AF remain symptomatic after rate control with medications and hence need anti-arrhythmic medications to maintain sinus rhythm. Among the multiple medications to prevent AF recurrence, amiodarone (AM) is the most effective. AM and dofetilide are the only 2 medications approved to prevent recurrence of AF in patients with left ventricular dysfunction. Most papers considered “low dose” AM to be between 200 and 300 mg daily. Even a recent review in a major journal recommended maintaining sinus rhythm (SR) with AM 200 to 300 mg daily. Two very small studies from China showed AM 100 mg to be effective. A recent unpublished report by McGrew demonstrated the impressive effectiveness of 100 mg or less of AM to prevent recurrence of AF. Objective: To determine the known AF free interval after first identification of receiving 100 mg AM or...
Abstract: The present study was conducted at Livestock Research and Development Station Surezai, ... more Abstract: The present study was conducted at Livestock Research and Development Station Surezai, Peshawar during June to August 2011. The objectives of this study were to determine the effect of Cotton Seed Cake (CSC) on milk yield, milk composition, feed intake, Body Condition Score (BCS) and live weight of Holstein Friesian (HF) crossbred cows. A total of nine mid-lactation crossbred cows were randomly distributed to three groups and allocated to diets containing zero (control), 20 and 35 percent CSC. All the three rations were Isocaloric and Isonitrogeniuos. Each cow was given a daily feed ration according to NRC standards. Mean daily milk yield differed (P<0.05) among all treatment groups. However, highest milk yield 5.68±0.096 kg/day was recorded for cows feed 35 % CSC while the control group (0 % CSC) produced the least yield 4.473±0.184 kg/day. Cows on 35 % CSC produced higher milk fat 4.46±0.22 percent and have significant (P<0.05) effect on milk fat content while the ...
The present cross sectional study was conducted on 350 Achai cattle (81male, 269 female) from Jan... more The present cross sectional study was conducted on 350 Achai cattle (81male, 269 female) from January, 2013 to May, 2013 at Livestock Research and Development Station Surezai, Peshawar, Peshawar Main Abattoir and 10 butcher shops in different regions (Swat, Malakand, Dir, Bajaur and Shangla) of the whole province to document the prevalence of rumen and reticulum foreign bodies and associated risk factors for the occurrence of foreign bodies in Achai Cattle which is known as local breed of the region, because many animals that have swallowed foreign bodies are asymptomatic, veterinarian must maintain a high index of suspicion in conducting post mortem examination. The study animals were selected by using stratified random sampling method from the study population. From the total of 350 animals examined, 207 (59.14%) were found positive for the occurrence of indigestible foreign bodies in rumen and reticulum. From each 81 male examined 30 (37.03%) and 269 female examined 177 (65.8%) w...
Abstract: Wheat crop is one of the most important cereal crops in all over the world, so, many ef... more Abstract: Wheat crop is one of the most important cereal crops in all over the world, so, many efforts have been taken to increase its yield from last many years, but higher yield requires modern innovations. This theoretical idea was existing among the some students of Sindh Agriculture University, Tandojam (Pkaistan)
Introduction: Human sexuality is generally described as the sum total of manner through which peo... more Introduction: Human sexuality is generally described as the sum total of manner through which people experience and articulate their sexual sensations. Female sexual dysfunction (FSD) is a continuum of psychosexual disorders centered on sexual desire with interrelated problems of arousal, orgasm and sexual pain that impairs quality of life for many women. Female sexual dysfunctions (FSDs) range from short-term aggravations to major emotional disturbances adversely affecting family and workplace. This research article is focus on the herbal treatment of psychosexual disorders of females. Objective: The purpose of this study is to find out the herbal treatment of the psychosexual disorders of females. Method: The duration of the study is 1 year, from July 2013 to June 2014. Total 40 patients randomly collected and divided into 2 groups. One is control group (CG) which received traditional therapy and one is Main group (MG) which received study drug Femion capsule for the 60 days. Pati...
Muhammad Rizwan,1, 2, ∗ Muhammad Zubair Ali,3, † and Ali Övgün4, 5, ‡ 1Department of Computer Sci... more Muhammad Rizwan,1, 2, ∗ Muhammad Zubair Ali,3, † and Ali Övgün4, 5, ‡ 1Department of Computer Science, Faculty of Engineering & Computer Sciences, National University of Modern Languages, H-9, Islamabad, Pakistan 2 School of Natural Sciences, National University of Sciences and Technology, H-12, Islamabad, Pakistan. 3Department of Mathematics and Statics, Faculty of Computational and Mathematical Sciences, University of Waikato Hamilton, 3216, New Zealand 4Instituto de Fı́sica, Pontificia Universidad Católica de Valparaı́so, Casilla 4950, Valparaı́so, Chile. 5Physics Department, Arts and Sciences Faculty, Eastern Mediterranean University, Famagusta, North Cyprus via Mersin 10, Turkey. (Dated: May 7, 2019)
Circulation-cardiovascular Quality and Outcomes, 2018
Importance: Atrial fibrillation (AF) is the most common rhythm abnormality of the heart and is pr... more Importance: Atrial fibrillation (AF) is the most common rhythm abnormality of the heart and is projected to double between 2010 and 2030. Many patients with AF remain symptomatic after rate control...
To evaluate safety and efficacy of Anti-pyretic granules in patients with upper respiratory tract... more To evaluate safety and efficacy of Anti-pyretic granules in patients with upper respiratory tract infection (URTI) with cough, cold, and flu symptoms along with pyrexia. Introduction: Herbs had been used by all cultures throughout history. Many drugs commonly used today are of herbal origin. The modern day scientific techniques have proven benefits of herbal drugs. The present study was designed to scrutinize the antipyretic activity of Herbion Anti-pyretic granules in patients with upper respiratory tract infection (URTI) including cough, cold, and flu along with mild to moderate fever. Method: Randomized open clinical study in 50 patients including Children, Adult Male and Female patients with pyrexia associated with cough, cold or flu. Herbion Anti-pyretic granules were given at a dose of 2-3 sachets/day to 50 patients and response of drug is recorded on the scheduled follow-up after 2days and 5days. Results: The overall results shows that out of 50 patients, 39 patients were rec...
Introduction: Erectile dysfunction (ED)is highly prevalent affecting almost 50% of men in the 40-... more Introduction: Erectile dysfunction (ED)is highly prevalent affecting almost 50% of men in the 40-70 year age range especially in those who have co-morbidities like diabetes, atherosclerosis, hypertension etc. Over recent years, the use of complementary and alternative medicines has become increasingly popular, and ED is one condition for which herbal supplements are heavily promoted and easily accessible. Traditional herbs have been a revolutionary breakthrough in the management of ED and have become known worldwide as ‘instant’ treatment. Major progress has been made in this field and at present a number of herbs are identified as a sexual stimulator. This knowledge has led to the discovery of several new therapeutic targets and multiple medical approaches for the treatment of erectile dysfunction (ED). This research focuses on the combination of selected herb in the treatment of ED. Aim: To examine the effects of Verona X tablet therapy on ED using the five-item version of the Int...
The present cross sectional study was conducted on 350 Achai cattle (81male, 269 female) from Jan... more The present cross sectional study was conducted on 350 Achai cattle (81male, 269 female) from January, 2013 to May, 2013 at Livestock Research and Development Station Surezai, Peshawar, Peshawar Main Abattoir and 10 butcher shops in different regions (Swat, Malakand, Dir, Bajaur and Shangla) of the whole province to document the prevalence of rumen and reticulum foreign bodies and associated risk factors for the occurrence of foreign bodies in Achai Cattle which is known as local breed of the region, because many animals that have swallowed foreign bodies are asymptomatic, veterinarian must maintain a high index of suspicion in conducting post mortem examination. The study animals were selected by using stratified random sampling method from the study population. From the total of 350 animals examined, 207 (59.14%) were found positive for the occurrence of indigestible foreign bodies in rumen and reticulum. From each 81 male examined 30 (37.03%) and 269 female examined 177 (65.8%) w...
This work examines the effect of co-doping the Si and Ge on the structure of graphene in terms of... more This work examines the effect of co-doping the Si and Ge on the structure of graphene in terms of the structural, electronic and optical properties based on First-principles (FPS) density functional theory calculations. The immersion of impurity atoms was increased from 8.33% to 12.5% and their causes on pure graphene characteristics were investigated. It is observed that, co-doping of Si and Ge atoms in graphene leads to broadening of band gap at the Dirac K-point. We also found that, co-doping of silicon and germanium atoms in graphene lattice significantly changes its optical parameters in the visible range of spectrum. These results suggest a unique method to tailor the optoelectronic properties of graphene layer which can be realized on experimental basis as well.
Objective: To investigate the therapeutic effects of the herbal medicated anti-lice shampoo a pro... more Objective: To investigate the therapeutic effects of the herbal medicated anti-lice shampoo a product of Herbion pharmaceutical on the head lice infiltration.Method: we collect the patients from government hospital Sharafigoth using the questionnaire and seeing the inclusion and exclusion criteria. Patients were advice to take bath with shampoo twice weekly. The instruction of using shampoo was explained to the patients briefly. After 4 week’s treatment we take the follow up and record the data.Result: Anti-lice shampoo is very effective in treatment of lice. Total 43 patients were treated with the anti-lice shampoo. Out of 100% (n=43)88.4% (n=38) shows marked improvement, 7% (n=3) shows moderate improvement and 4.7% (n=2) shows mild improvement.Conclusion: Herbion anti-lice shampoo is very effective in treating the lice infestation.
Results: Result shown that the total body weight of Cobb-500 and Ross-308 on 1 week was 207.40±14... more Results: Result shown that the total body weight of Cobb-500 and Ross-308 on 1 week was 207.40±14 gram and 196.00±16 gram respectively and these result represented significant difference of weight gain (P<0.05) on 1 week of experiment among both the strains. From 2 week of experiment till the last week (5 week) the results shown the total body weight of Cob-500 and Ross-308 as 2180.4±38 gram and 2103.7±36 gram respectively which was non-significantly different (P>0.05) among the strains. Furthermore, significant difference of feed conversion ratio (FCR) was observed (P<0.05) among both the strains but from day 7 till the market age weekly FCR of Cob-500 was significantly higher (P<0.05) than Ross-308. Comparatively high mortality (4.8±0.4%) was noticed in Ross broiler strain than Cobb broiler strain (3.7±0.4%).
Abstract Graphene oxide (GO) based membranes have been widely explored for water purification and... more Abstract Graphene oxide (GO) based membranes have been widely explored for water purification and desalination applications, however, it shows less rejection for small ions and molecules, due to lack of pristine graphitic sp2 domains and smaller interlayer spacing. In this work, we fabricate a unique class of GO based composite (cGO) membranes with large interlayer spacing from GO by serine amino acid (SAA) as a cross-linker and reducing agent using simple strategy. The cGO/SAA membrane (~280 ± 20 nm) showed an outstanding separation efficiency for several organic dyes with ultrafast permeability i.e. rhodamine B (Rejection 99 ± 1% and permeance 930 ± 10 Lm−2h−1bar−1), methyl blue (98 ± 1% and permeance 980 ± 10 Lm−2h−1bar−1) and DI water (1050 ± 10 Lm−2h−1bar−1). In addition, these membranes were also used for the separation of different salts such as NaCl, MgCl2, Ni(NO3)2 and Pb(NO3)2 and show good rejection for Pb(NO3)2 up to 92 ± 2%. Beside this, these membranes found to be very stable in aqueous environment for ~65 days. We believe with the help of this strategy, various 2D materials based membranes can be developed and used in water filtration and desalination.
Genetic defects in cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene cause CF.... more Genetic defects in cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene cause CF. Infants with CFTR mutations show a peribronchial neutrophil infiltration prior to the establishment of infection in their lung. The inflammatory response progressively increases in children that include both upper and lower airways. Infectious and inflammatory response leads to an increase in mucus viscosity and mucus plugging of small and medium-size bronchioles. Eventually, neutrophils chronically infiltrate the airways with biofilm or chronic bacterial infection. Perpetual infection and airway inflammation destroy the lungs, which leads to increased morbidity and eventual mortality in most of the patients with CF. Studies have now established that neutrophil cytotoxins, extracellular DNA, and neutrophil extracellular traps (NETs) are associated with increased mucus clogging and lung injury in CF. In addition to opportunistic pathogens, various aspects of the CF airway milieux (e.g., ...
New procedures are required to optimize the use of blood samples to study different cell types. T... more New procedures are required to optimize the use of blood samples to study different cell types. The purification of neutrophils and T cells from the same blood sample is not commonly described. We have previously used PolymorphPrep™ (P) or LymphoPrep™ (L) for purifying neutrophils or T cells, respectively. In this study, we describe a new method for purifying both of these cells using P and L from the same sample, and methodological considerations required to obtain consistent Th17 differentiation results. For T cell studies, we first isolated mononuclear cells from peripheral blood of healthy humans using either P alone, L alone or sequential isolation with P and then L (P + L). CD3+ lymphocytes comprise up to 73% of peripheral blood mononuclear cells (PBMCs) obtained by sequential isolation, with 29% and 36% for P and L, respectively. T lymphocyte subsets, Th1, Th17 or double-positive (Th17/1), were then amplified. Four days of amplification culture after isolation by P alone led to over-expression of Th17/1 cells and of Th17 cells in comparison to cells isolated by L or by sequential P + L. Th17/1 cells comprised 11.0 ± 6.8% (P alone) vs 1.2 ± 0.28% (L alone) vs 0.45 ± 0.11% (P + L) and Th17 cells comprised 2.8 ± 0.4% (P alone) 0.88 ± 0.15% (L alone) vs 0.86 ± 0.14% (P + L). As the second step, we examined T cell purification and differentiation. A higher purity of 97.1 ± 0.44% naïve CD4+ T cell was reached after P + L followed by immunomagnetic bead sorting in comparison to 70 ± 9.3% (L) vs 21.0 ± 8.5% (P). These cells grew well in the density range of 25, 000 to 100, 000 cells per well in 96-well plates during Th17 cell differentiation; higher or lower cell density did not support Th17 cell differentiation. Lastly, to investigate the effect of estrogen on Th17 cell differentiation, serum-free AIM V medium without phenol red was chosen to minimize the hormonal effects of the medium. We found that exogenous estrogen (1 nM) inhibited Th17 cell differentiation in this medium. Taken together, we devised a method to isolate both neutrophils and T cells from the same blood sample and show that high PBMC purity, selected culture medium and an optimal cell density of the initial cell culture produced the most robust and consistent results for Th17 differentiation.
… Background: It is mandatory to distinguish between primary ovarian tumors and metastases, as th... more … Background: It is mandatory to distinguish between primary ovarian tumors and metastases, as the treatment and prognoses are wide apart. Immunohistochemistry is most frequently method being used to distinct these. Multiple studies showed that CDX2 is hallmark of the gut epithelium and is highly sensitive and specific immunohistochemical marker for neoplasms of gastrointestinal origin. Objectives: In this case series study we have clinically and radiologically evaluated the cases of ovarian tumors referred to our institute, which are reported metastatic from colon based on expression of CDX2 marker. Study Design: Cross sectional observational study.
Upper respiratory tract infections (URTI) are the most common acute illnesses that are often of v... more Upper respiratory tract infections (URTI) are the most common acute illnesses that are often of viral origin. Cough and chest congestion are the common symptoms of this disease. Children are prescribed with drugs that are considered to relive the symptoms of this disease. The topical medications contain vegetable camphor for more than a century that relieve chest congestion and cough caused by URTI. The use of camphor in such products remains questionable especially in children who are more sensitive to its side effects. Herbion "Chest Rub" for children is a camphor-free formulation that contains eucalyptus oil mixture, menthol,turpentine and clove oils and is used to relieve symptoms of URTI.The objective of the present investigationwas to determine the effectiveness of the chest rub inchildren suffering with congestion and cough caused by URTI. The study compared the results of the chest rub applied to a group of infected children with a placebo group. Patients were sele...
Importance: Atrial fibrillation (AF) is the most common rhythm abnormality of the heart and is pr... more Importance: Atrial fibrillation (AF) is the most common rhythm abnormality of the heart and is projected to double between 2010 and 2030. Many patients with AF remain symptomatic after rate control with medications and hence need anti-arrhythmic medications to maintain sinus rhythm. Among the multiple medications to prevent AF recurrence, amiodarone (AM) is the most effective. AM and dofetilide are the only 2 medications approved to prevent recurrence of AF in patients with left ventricular dysfunction. Most papers considered “low dose” AM to be between 200 and 300 mg daily. Even a recent review in a major journal recommended maintaining sinus rhythm (SR) with AM 200 to 300 mg daily. Two very small studies from China showed AM 100 mg to be effective. A recent unpublished report by McGrew demonstrated the impressive effectiveness of 100 mg or less of AM to prevent recurrence of AF. Objective: To determine the known AF free interval after first identification of receiving 100 mg AM or...
Abstract: The present study was conducted at Livestock Research and Development Station Surezai, ... more Abstract: The present study was conducted at Livestock Research and Development Station Surezai, Peshawar during June to August 2011. The objectives of this study were to determine the effect of Cotton Seed Cake (CSC) on milk yield, milk composition, feed intake, Body Condition Score (BCS) and live weight of Holstein Friesian (HF) crossbred cows. A total of nine mid-lactation crossbred cows were randomly distributed to three groups and allocated to diets containing zero (control), 20 and 35 percent CSC. All the three rations were Isocaloric and Isonitrogeniuos. Each cow was given a daily feed ration according to NRC standards. Mean daily milk yield differed (P<0.05) among all treatment groups. However, highest milk yield 5.68±0.096 kg/day was recorded for cows feed 35 % CSC while the control group (0 % CSC) produced the least yield 4.473±0.184 kg/day. Cows on 35 % CSC produced higher milk fat 4.46±0.22 percent and have significant (P<0.05) effect on milk fat content while the ...
The present cross sectional study was conducted on 350 Achai cattle (81male, 269 female) from Jan... more The present cross sectional study was conducted on 350 Achai cattle (81male, 269 female) from January, 2013 to May, 2013 at Livestock Research and Development Station Surezai, Peshawar, Peshawar Main Abattoir and 10 butcher shops in different regions (Swat, Malakand, Dir, Bajaur and Shangla) of the whole province to document the prevalence of rumen and reticulum foreign bodies and associated risk factors for the occurrence of foreign bodies in Achai Cattle which is known as local breed of the region, because many animals that have swallowed foreign bodies are asymptomatic, veterinarian must maintain a high index of suspicion in conducting post mortem examination. The study animals were selected by using stratified random sampling method from the study population. From the total of 350 animals examined, 207 (59.14%) were found positive for the occurrence of indigestible foreign bodies in rumen and reticulum. From each 81 male examined 30 (37.03%) and 269 female examined 177 (65.8%) w...
Abstract: Wheat crop is one of the most important cereal crops in all over the world, so, many ef... more Abstract: Wheat crop is one of the most important cereal crops in all over the world, so, many efforts have been taken to increase its yield from last many years, but higher yield requires modern innovations. This theoretical idea was existing among the some students of Sindh Agriculture University, Tandojam (Pkaistan)
Introduction: Human sexuality is generally described as the sum total of manner through which peo... more Introduction: Human sexuality is generally described as the sum total of manner through which people experience and articulate their sexual sensations. Female sexual dysfunction (FSD) is a continuum of psychosexual disorders centered on sexual desire with interrelated problems of arousal, orgasm and sexual pain that impairs quality of life for many women. Female sexual dysfunctions (FSDs) range from short-term aggravations to major emotional disturbances adversely affecting family and workplace. This research article is focus on the herbal treatment of psychosexual disorders of females. Objective: The purpose of this study is to find out the herbal treatment of the psychosexual disorders of females. Method: The duration of the study is 1 year, from July 2013 to June 2014. Total 40 patients randomly collected and divided into 2 groups. One is control group (CG) which received traditional therapy and one is Main group (MG) which received study drug Femion capsule for the 60 days. Pati...
Muhammad Rizwan,1, 2, ∗ Muhammad Zubair Ali,3, † and Ali Övgün4, 5, ‡ 1Department of Computer Sci... more Muhammad Rizwan,1, 2, ∗ Muhammad Zubair Ali,3, † and Ali Övgün4, 5, ‡ 1Department of Computer Science, Faculty of Engineering & Computer Sciences, National University of Modern Languages, H-9, Islamabad, Pakistan 2 School of Natural Sciences, National University of Sciences and Technology, H-12, Islamabad, Pakistan. 3Department of Mathematics and Statics, Faculty of Computational and Mathematical Sciences, University of Waikato Hamilton, 3216, New Zealand 4Instituto de Fı́sica, Pontificia Universidad Católica de Valparaı́so, Casilla 4950, Valparaı́so, Chile. 5Physics Department, Arts and Sciences Faculty, Eastern Mediterranean University, Famagusta, North Cyprus via Mersin 10, Turkey. (Dated: May 7, 2019)
Circulation-cardiovascular Quality and Outcomes, 2018
Importance: Atrial fibrillation (AF) is the most common rhythm abnormality of the heart and is pr... more Importance: Atrial fibrillation (AF) is the most common rhythm abnormality of the heart and is projected to double between 2010 and 2030. Many patients with AF remain symptomatic after rate control...
To evaluate safety and efficacy of Anti-pyretic granules in patients with upper respiratory tract... more To evaluate safety and efficacy of Anti-pyretic granules in patients with upper respiratory tract infection (URTI) with cough, cold, and flu symptoms along with pyrexia. Introduction: Herbs had been used by all cultures throughout history. Many drugs commonly used today are of herbal origin. The modern day scientific techniques have proven benefits of herbal drugs. The present study was designed to scrutinize the antipyretic activity of Herbion Anti-pyretic granules in patients with upper respiratory tract infection (URTI) including cough, cold, and flu along with mild to moderate fever. Method: Randomized open clinical study in 50 patients including Children, Adult Male and Female patients with pyrexia associated with cough, cold or flu. Herbion Anti-pyretic granules were given at a dose of 2-3 sachets/day to 50 patients and response of drug is recorded on the scheduled follow-up after 2days and 5days. Results: The overall results shows that out of 50 patients, 39 patients were rec...
Introduction: Erectile dysfunction (ED)is highly prevalent affecting almost 50% of men in the 40-... more Introduction: Erectile dysfunction (ED)is highly prevalent affecting almost 50% of men in the 40-70 year age range especially in those who have co-morbidities like diabetes, atherosclerosis, hypertension etc. Over recent years, the use of complementary and alternative medicines has become increasingly popular, and ED is one condition for which herbal supplements are heavily promoted and easily accessible. Traditional herbs have been a revolutionary breakthrough in the management of ED and have become known worldwide as ‘instant’ treatment. Major progress has been made in this field and at present a number of herbs are identified as a sexual stimulator. This knowledge has led to the discovery of several new therapeutic targets and multiple medical approaches for the treatment of erectile dysfunction (ED). This research focuses on the combination of selected herb in the treatment of ED. Aim: To examine the effects of Verona X tablet therapy on ED using the five-item version of the Int...
The present cross sectional study was conducted on 350 Achai cattle (81male, 269 female) from Jan... more The present cross sectional study was conducted on 350 Achai cattle (81male, 269 female) from January, 2013 to May, 2013 at Livestock Research and Development Station Surezai, Peshawar, Peshawar Main Abattoir and 10 butcher shops in different regions (Swat, Malakand, Dir, Bajaur and Shangla) of the whole province to document the prevalence of rumen and reticulum foreign bodies and associated risk factors for the occurrence of foreign bodies in Achai Cattle which is known as local breed of the region, because many animals that have swallowed foreign bodies are asymptomatic, veterinarian must maintain a high index of suspicion in conducting post mortem examination. The study animals were selected by using stratified random sampling method from the study population. From the total of 350 animals examined, 207 (59.14%) were found positive for the occurrence of indigestible foreign bodies in rumen and reticulum. From each 81 male examined 30 (37.03%) and 269 female examined 177 (65.8%) w...
This work examines the effect of co-doping the Si and Ge on the structure of graphene in terms of... more This work examines the effect of co-doping the Si and Ge on the structure of graphene in terms of the structural, electronic and optical properties based on First-principles (FPS) density functional theory calculations. The immersion of impurity atoms was increased from 8.33% to 12.5% and their causes on pure graphene characteristics were investigated. It is observed that, co-doping of Si and Ge atoms in graphene leads to broadening of band gap at the Dirac K-point. We also found that, co-doping of silicon and germanium atoms in graphene lattice significantly changes its optical parameters in the visible range of spectrum. These results suggest a unique method to tailor the optoelectronic properties of graphene layer which can be realized on experimental basis as well.
Objective: To investigate the therapeutic effects of the herbal medicated anti-lice shampoo a pro... more Objective: To investigate the therapeutic effects of the herbal medicated anti-lice shampoo a product of Herbion pharmaceutical on the head lice infiltration.Method: we collect the patients from government hospital Sharafigoth using the questionnaire and seeing the inclusion and exclusion criteria. Patients were advice to take bath with shampoo twice weekly. The instruction of using shampoo was explained to the patients briefly. After 4 week’s treatment we take the follow up and record the data.Result: Anti-lice shampoo is very effective in treatment of lice. Total 43 patients were treated with the anti-lice shampoo. Out of 100% (n=43)88.4% (n=38) shows marked improvement, 7% (n=3) shows moderate improvement and 4.7% (n=2) shows mild improvement.Conclusion: Herbion anti-lice shampoo is very effective in treating the lice infestation.
Results: Result shown that the total body weight of Cobb-500 and Ross-308 on 1 week was 207.40±14... more Results: Result shown that the total body weight of Cobb-500 and Ross-308 on 1 week was 207.40±14 gram and 196.00±16 gram respectively and these result represented significant difference of weight gain (P<0.05) on 1 week of experiment among both the strains. From 2 week of experiment till the last week (5 week) the results shown the total body weight of Cob-500 and Ross-308 as 2180.4±38 gram and 2103.7±36 gram respectively which was non-significantly different (P>0.05) among the strains. Furthermore, significant difference of feed conversion ratio (FCR) was observed (P<0.05) among both the strains but from day 7 till the market age weekly FCR of Cob-500 was significantly higher (P<0.05) than Ross-308. Comparatively high mortality (4.8±0.4%) was noticed in Ross broiler strain than Cobb broiler strain (3.7±0.4%).
Abstract Graphene oxide (GO) based membranes have been widely explored for water purification and... more Abstract Graphene oxide (GO) based membranes have been widely explored for water purification and desalination applications, however, it shows less rejection for small ions and molecules, due to lack of pristine graphitic sp2 domains and smaller interlayer spacing. In this work, we fabricate a unique class of GO based composite (cGO) membranes with large interlayer spacing from GO by serine amino acid (SAA) as a cross-linker and reducing agent using simple strategy. The cGO/SAA membrane (~280 ± 20 nm) showed an outstanding separation efficiency for several organic dyes with ultrafast permeability i.e. rhodamine B (Rejection 99 ± 1% and permeance 930 ± 10 Lm−2h−1bar−1), methyl blue (98 ± 1% and permeance 980 ± 10 Lm−2h−1bar−1) and DI water (1050 ± 10 Lm−2h−1bar−1). In addition, these membranes were also used for the separation of different salts such as NaCl, MgCl2, Ni(NO3)2 and Pb(NO3)2 and show good rejection for Pb(NO3)2 up to 92 ± 2%. Beside this, these membranes found to be very stable in aqueous environment for ~65 days. We believe with the help of this strategy, various 2D materials based membranes can be developed and used in water filtration and desalination.
Genetic defects in cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene cause CF.... more Genetic defects in cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene cause CF. Infants with CFTR mutations show a peribronchial neutrophil infiltration prior to the establishment of infection in their lung. The inflammatory response progressively increases in children that include both upper and lower airways. Infectious and inflammatory response leads to an increase in mucus viscosity and mucus plugging of small and medium-size bronchioles. Eventually, neutrophils chronically infiltrate the airways with biofilm or chronic bacterial infection. Perpetual infection and airway inflammation destroy the lungs, which leads to increased morbidity and eventual mortality in most of the patients with CF. Studies have now established that neutrophil cytotoxins, extracellular DNA, and neutrophil extracellular traps (NETs) are associated with increased mucus clogging and lung injury in CF. In addition to opportunistic pathogens, various aspects of the CF airway milieux (e.g., ...
New procedures are required to optimize the use of blood samples to study different cell types. T... more New procedures are required to optimize the use of blood samples to study different cell types. The purification of neutrophils and T cells from the same blood sample is not commonly described. We have previously used PolymorphPrep™ (P) or LymphoPrep™ (L) for purifying neutrophils or T cells, respectively. In this study, we describe a new method for purifying both of these cells using P and L from the same sample, and methodological considerations required to obtain consistent Th17 differentiation results. For T cell studies, we first isolated mononuclear cells from peripheral blood of healthy humans using either P alone, L alone or sequential isolation with P and then L (P + L). CD3+ lymphocytes comprise up to 73% of peripheral blood mononuclear cells (PBMCs) obtained by sequential isolation, with 29% and 36% for P and L, respectively. T lymphocyte subsets, Th1, Th17 or double-positive (Th17/1), were then amplified. Four days of amplification culture after isolation by P alone led to over-expression of Th17/1 cells and of Th17 cells in comparison to cells isolated by L or by sequential P + L. Th17/1 cells comprised 11.0 ± 6.8% (P alone) vs 1.2 ± 0.28% (L alone) vs 0.45 ± 0.11% (P + L) and Th17 cells comprised 2.8 ± 0.4% (P alone) 0.88 ± 0.15% (L alone) vs 0.86 ± 0.14% (P + L). As the second step, we examined T cell purification and differentiation. A higher purity of 97.1 ± 0.44% naïve CD4+ T cell was reached after P + L followed by immunomagnetic bead sorting in comparison to 70 ± 9.3% (L) vs 21.0 ± 8.5% (P). These cells grew well in the density range of 25, 000 to 100, 000 cells per well in 96-well plates during Th17 cell differentiation; higher or lower cell density did not support Th17 cell differentiation. Lastly, to investigate the effect of estrogen on Th17 cell differentiation, serum-free AIM V medium without phenol red was chosen to minimize the hormonal effects of the medium. We found that exogenous estrogen (1 nM) inhibited Th17 cell differentiation in this medium. Taken together, we devised a method to isolate both neutrophils and T cells from the same blood sample and show that high PBMC purity, selected culture medium and an optimal cell density of the initial cell culture produced the most robust and consistent results for Th17 differentiation.
… Background: It is mandatory to distinguish between primary ovarian tumors and metastases, as th... more … Background: It is mandatory to distinguish between primary ovarian tumors and metastases, as the treatment and prognoses are wide apart. Immunohistochemistry is most frequently method being used to distinct these. Multiple studies showed that CDX2 is hallmark of the gut epithelium and is highly sensitive and specific immunohistochemical marker for neoplasms of gastrointestinal origin. Objectives: In this case series study we have clinically and radiologically evaluated the cases of ovarian tumors referred to our institute, which are reported metastatic from colon based on expression of CDX2 marker. Study Design: Cross sectional observational study.
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Papers by Zubair Ali