Papers by Zoza Travels India Immigration Services
International Journal of Health Sciences (IJHS), Jul 20, 2022
In the present society, the energy drinks (EDs) are used by general public and mainly by the spor... more In the present society, the energy drinks (EDs) are used by general public and mainly by the sports persons. Though the caffeine content of EDs is creating health consequences on excess consumption, the present study targets their health benefits on central nervous system (CNS) focusing antidepressant and cognitive 5440 potentiality. The most typically used EDs have been selected for the study such as Red Bull, Monster and Enerzal for the present research. Methodology: The study started with in-silico studies to get information about the neurological receptor binding of the major and common chemical components of the EDs. The antidepressant study of energy drinks was carried out following FST (Forced Swim Test) and TST (Tail suspension test) methods. Their cognition effect was assessed by using Y-maze apparatus. Further, their mechanism of action was evaluated by estimating their effect on brain dopamine and serotonin level. Results: In-silico study revealed the enhanced agonistic binding of the major common components of the EDs to D2 and serotonin receptors. Further their significant (p<0.001) antidepressant property was estimated both in tail suspension and forced swim tests along with significant cognitive property. The mechanism behind these effects were confirmed by their potentiation in the brain dopamine and serotonin concentration significantly (p<0.001) in mice. Conclusion: The present study may be beneficial to utilise the EDs in a better prospective for the management of CNS depression and improving the cognition, where Red bull was considered to be the superior one to others after their further confirmatory studies in clinical trials.
World Journal of Stem Cells
The art of constructing an insightful literature review manuscript has witnessed an exemplar in t... more The art of constructing an insightful literature review manuscript has witnessed an exemplar in the work of Oz et al (2023), wherein concept progression harmoniously merges with figures and tables. Reflecting on retrospective data science, it is evident that well-cited articles can wield a transformative influence on the Journal Citation Reports Impact Factor score, as exemplified by Robert Weinberg’s landmark on cancer (Hanahan and Weinberg, 2011). Here, we aim to spotlight a commendable contribution by Tuba Oz, Ajeet Kaushik, and Małgorzata Kujawska in this issue while pivoting towards identifying the hallmarks of a subpar literature review-elements that hinder rather than promote advancement. The hurdles and roadblocks encountered within subpar literature reviews are multifold. Anticipation of emerging trends, identification of challenges, and exploration of solutions remain conspicuously absent. Original Contributions fail to surface amidst the vast sea of pre-existing literatur...
Journal of Virus Eradication
Electronics
Multilevel inverters, known for their low switching loss and suitability for medium- to high-powe... more Multilevel inverters, known for their low switching loss and suitability for medium- to high-power applications, often create a heavy computational overhead for the controller. This paper addresses the aforementioned limitation by presenting a novel approach to Direct Model Predictive Control (DMPC) for a grid-tied 289-level ladder multilevel inverter (LMLI). The primary objective is to achieve perfect inverter current control without enumeration. The proposed control method provides a single best solution without complete exploration of the search space. This generalized method can be applied to any multilevel inverter (MLI), enabling them to be used in the grid-tied mode without the computational burden due to a large number of switching states. The DMPC of LMLI with 289-level output and corresponding 289 control inputs, utilizes a discrete model to predict the future state of the state variable. In order to alleviate the enumeration burden, virtual sectors on a linear scale are i...
Regenerative Engineering and Translational Medicine
Stem Cell Reviews and Reports
World Journal of Stem Cells
Acute pancreatitis (AP) often leads to a high incidence of cardiac injury, posing significant cha... more Acute pancreatitis (AP) often leads to a high incidence of cardiac injury, posing significant challenges in the treatment of severe AP and contributing to increased mortality rates. Mesenchymal stem cells (MSCs) release bioactive molecules that participate in various inflammatory diseases. Similarly, extracellular vesicles (EVs) secreted by MSCs have garnered extensive attention due to their comparable anti-inflammatory effects to MSCs and their potential to avoid risks associated with cell transplantation. Recently, the therapeutic potential of MSCs-EVs in various inflammatory diseases, including sepsis and AP, has gained increasing recognition. Although preclinical research on the utilization of MSCs-EVs in AP-induced cardiac injury is limited, several studies have demonstrated the positive effects of MSCs-EVs in regulating inflammation and immunity in sepsis-induced cardiac injury and cardiovascular diseases. Furthermore, clinical studies have been conducted on the therapeutic ap...
The Journal of Arthroplasty
Sustainability
Recently, different metaheuristic techniques, their variants, and hybrid forms have been extensiv... more Recently, different metaheuristic techniques, their variants, and hybrid forms have been extensively used to solve economic load dispatch (ELD) problems with and without valve point loading (VPL) effects. Due to the randomization involved in these metaheuristic techniques, one has to perform extensive runs for each experiment to get an optimal solution. The process may sometimes become laborious and time-consuming to converge to an optimal solution. On the other hand, advanced calculus-based techniques, being deterministic, perform iteration systematically and come up with the same solution on each run of the experiment. Since ELD problems are constrained optimization problems, we are proposing the constrained (deterministic) optimization algorithm for their solutions. Various 13-unit, 38-unit, and 40-unit thermal test systems are considered. Valve point loading (VPL) effects are also considered in some cases. Computer-based numerical results depict that the constrained optimization...
The Journal of Arthroplasty
Current Issues in Molecular Biology
Background: Demyelinating diseases represent a broad spectrum of disorders and are characterized ... more Background: Demyelinating diseases represent a broad spectrum of disorders and are characterized by the loss of specialized glial cells (oligodendrocytes), which eventually leads to neuronal degeneration. Stem cell-based regenerative approaches provide therapeutic options to regenerate demyelination-induced neurodegeneration. Objectives: The current study aims to explore the role of oligodendrocyte-specific transcription factors (OLIG2 and MYT1L) under suitable media composition to facilitate human umbilical-cord-derived mesenchymal stem cells (hUC-MSCs) differentiation toward oligodendrocyte for their potential use to treat demyelinating disorders. Methodology: hUC-MSCs were isolated, cultured, and characterized based on their morphological and phenotypic characteristics. hUC-MSCs were transfected with OLIG2 and MYT1L transcription factors individually and in synergistic (OLIG2 + MYT1L) groups using a lipofectamine-based transfection method and incubated under two different media c...
Energies
Plug-in hybrid electric vehicles (PHEVs) and plug-in electric vehicles (PEVs) have gained enormou... more Plug-in hybrid electric vehicles (PHEVs) and plug-in electric vehicles (PEVs) have gained enormous attention for their ability to reduce fuel consumption in transportation and are, thus, helpful in the reduction of the greenhouse effect and pollution. However, they bring up some technical problems that should be resolved. Due to the ever-increasing demand for these PHEVs, the simultaneous connection of large PEVs and PHEVs to the electric grid can cause overloading, which results in disturbance to overall power system stability and quality and can cause a blackout. Such situations can be avoided by adequately manipulating power available from the grid and vehicle power demand. State of charge (SoC) is the leading performance parameter that should be optimized using computational techniques to charge vehicles efficiently. In this research, an efficient metaheuristic algorithm, accelerated particle swarm optimization (APSO), and its five variants were applied to allocate power to vehi...
Journal of Bone and Joint Surgery
Background: Hyponatremia is a common electrolyte abnormality in arthroplasty patients. This issue... more Background: Hyponatremia is a common electrolyte abnormality in arthroplasty patients. This issue, underrecognized by surgeons, can impact the postoperative course of patients. There are, however, little data on the implications of sodium disturbances following total joint arthroplasty (TJA). The primary aims of this study were to (1) report the rate of hyponatremia following TJA, and (2) examine the impact of hyponatremia on the perioperative course of TJA patients. Methods: This was a retrospective analysis of 3,071 primary and revision TJAs performed between 2015 and 2017. Based on preoperative and postoperative sodium values (pre-post), patients were classified into 4 groups: normonatremic-normonatremic (Group 1), normonatremic-hyponatremic (Group 2), hyponatremic-normonatremic (Group 3), and hyponatremic-hyponatremic (Group 4). Primary end points were length of stay (LOS), postoperative discharge, in-hospital complications, and 90-day readmissions. Results: The distribution of ...
2023 IEEE Texas Power and Energy Conference (TPEC)
Frontiers in Medicine
BackgroundIntervertebral disc (IVD) shows aging and degenerative changes earlier than any other b... more BackgroundIntervertebral disc (IVD) shows aging and degenerative changes earlier than any other body connective tissue. Its repair and regeneration provide a considerable challenge in regenerative medicine due to its high degree of infrastructure and mechanical complexity. Mesenchymal stem cells, due to their tissue resurfacing potential, represent many explanatory pathways to regenerate a tissue breakdown.MethodsThis study was undertaken to evaluate the co-regulation of Sox9 and TGFβ1 in differentiating human umbilical cord mesenchymal stem cells (hUC-MSC) into chondrocytes. The combinatorial impact of Sox9 and TGFβ1 on hUC-MSCs was examined in vitro by gene expression and immunocytochemical staining. In in vivo, an animal model of IVD degeneration was established under a fluoroscopic guided system through needle puncture of the caudal disc. Normal and transfected MSCs were transplanted. Oxidative stress, pain, and inflammatory markers were evaluated by qPCR. Disc height index (DHI...
Sustainability
The Cascaded Short-Term Hydrothermal Scheduling (CSTHTS) problem is a highly non-linear, multi-mo... more The Cascaded Short-Term Hydrothermal Scheduling (CSTHTS) problem is a highly non-linear, multi-modal, non-convex, and NP-hard optimization problem that has been solved by conventional and metaheuristic algorithms in the past. As the CSTHTS problem falls under the category of applied operational research, therefore, the work is still on-going to find new algorithms and variants of the existing algorithms that would better approximate the optimal global solution in a shorter computational time. This article proposes a novel deterministic thermal economic dispatch method embedded with the improved Accelerated Particle Swarm Optimization (APSO) algorithm to infinitesimally reduce the Big O time complexity for the standard benchmark test case of the CSTHTS optimization problem. Then, it discusses and presents the importance of performing standard statistical tests to establish the supremacy of one metaheuristic algorithm over the other one in solving the CSTHTS problem. The results obtai...
The Journal of Arthroplasty
Animal Nutrition and Feed Technology
Energies
In developing countries, many areas are deprived of electrical energy. Access to cleaner, more af... more In developing countries, many areas are deprived of electrical energy. Access to cleaner, more affordable energy is critical for improving the poor’s living conditions in developing countries. With the advent of smart grid technology, the integration and coordination of small grids, known as nanogrids, has become very easy. The purpose of this research is to propose a nanogrid model that will serve the purpose of providing the facility of electrical power to the poor rural community in Pakistan using hybrid renewable energy sources. This paper targets the electrification of a poor rural community of Akora Khatak, a small district located in Pakistan. The mathematical modeling of solar and wind energy, neural network-based forecasting of solar irradiance and wind velocity, and the social analysis to calculate the payback period for the community have been discussed in this paper.
Mathematics
The objective of the present paper is to study the optimum installation of Non-dispatchable Distr... more The objective of the present paper is to study the optimum installation of Non-dispatchable Distributed Generations (NDG) in the distribution network of given sizes under the given scheme. The uncertainty of various random (uncertain) parameters like load, wind and solar operated DG besides uncertainty of fuel prices has been investigated by the three-point estimate method (3-PEM) and Monte Carlo Simulation (MCS) based methods. Nearly twenty percent of the total number of buses are selected as candidate buses for NDG placement on the basis of system voltage profile to limit the search space. Weibull probability density function (PDF) is considered to address uncertain characteristics of solar radiation and wind speed under different scenarios. Load uncertainty is described by Standard Normal Distribution Function (SNDF). To investigate the solution of optimal probabilistic load flow (OPLF) three-point PEM-based technique was applied. For optimization, Genetic Algorithm (GA), Particl...
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Papers by Zoza Travels India Immigration Services