International Association for Development of the Information Society, 2015
Living conditions and social environment are changing through time, and recently schooling popula... more Living conditions and social environment are changing through time, and recently schooling population is diminishing in Korea. Thus the number of abandoned schools has increased. In order to utilize unused space a mechanism is required for the exchange of various ideas. However, there is little effort to provide a platform for this purpose. This study aims at developing a process and a systemic method to collect intelligence of utilizing unused space.
Recently, a variety of efforts have been taken to convey sustainable management strategies of spo... more Recently, a variety of efforts have been taken to convey sustainable management strategies of sports apparel brands through single-person media. However, there is a lack of theoretical information on the path that leads these corporate marketing activities to brand reliability and purchase intention of consumers. Therefore, this study aims to analyze the path through which the sustainable management strategy established by a sports apparel brand affects the brand awareness and reliability, as well as the purchase intention of consumers when experiencing this strategy through single-person media. The results are summarized as follows: Firstly, the sustainable management strategies of a sports apparel brand carried out through single-person media had statistically significant positive impacts on the benevolence reliability perceived by single-person media viewers. Secondly, benevolence also had a statistically significant positive impact on the consumers’ purchase intention. It is exp...
2018 IEEE International Conference on Consumer Electronics (ICCE), 2018
Due to the rapid increase in the production of portable digital audio devices and the continuous ... more Due to the rapid increase in the production of portable digital audio devices and the continuous upgrades to internet access speeds, the market for MQS(Mastering Quality Sound) audio is growing rapidly as the format possesses higher audio quality than MP3. Unlike MP3 or CD formats that result in loss of quality and resolution, MQS represents the original audio recording of the singer in the studio with no loss in audio quality, and utilizes lossless audio codecs for compression to maintain the highest quality. While the most commonly used lossless audio codec is FLAC, the compression rate of this codec is not effective, resulting in large file sizes and overhead when conventional DRM is applied. This paper presents a new DRM model that allows for low-quality previews and minimizes battery drain in smartphones. This model has already been implemented on the Android platform, and usability has been evaluated.
Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2017
Cartilage regeneration was found in 39 knees (70.0%) at the second-look arthroscopy. While BSS of... more Cartilage regeneration was found in 39 knees (70.0%) at the second-look arthroscopy. While BSS of the medial compartment was significantly decreased from 3.6 AE 1.5 to 1.4 AE 0.4 (p<0.01) after OWTHO, BSS of the lateral compartment did not change postoperatively. Postoperative BSS of the medial compartment significantly correlated with VAS, KOOS and WBLR. No statistical significant associations between BTU and cartilage regeneration were found. Conclusion: OWHTO led to a significant decrease in BTU of the medial compartment, which correlated well with knee pain and postoperative mechanical alignment. Despite shifting the weight bearing line to the lateral compartment, no increased postoperative BTU was found in the lateral compartment. This observation demonstrated that OWHTO does not cause overloading in the lateral compartment.
Background: The LDL receptor is a cell-surface protein that regulates plasma cholesterol by speci... more Background: The LDL receptor is a cell-surface protein that regulates plasma cholesterol by specific uptake of LDL particles from the blood circulation. Familial hypercholesterolemia (FH) results from defective catabolism of LDL, which is caused by mutations in the LDL-receptor gene.Methods: For the rapid and reliable detection of large rearrangements in the LDL-receptor gene, we established a screening method based on long-distance PCR as an alternative to Southern-blot hybridization. Using long-distance PCR, 45 unrelated Korean subjects heterozygous for FH were screened to assess the frequency and nature of major structural rearrangements in the LDL-receptor gene.Results: Two different deletion mutations, FH6 (same type as FH3 and FH311) and FH 32, were detected in four families by long-distance PCR. Detailed restriction mapping and sequence analysis showed that FH6 was a 5.71-kb deletion extending from intron 8 to intron 12 and that FH32 was a 2-kb deletion extending from intron ...
This research aimed to examine the conceptual map of pedagogical content knowledge(PCK) of prospe... more This research aimed to examine the conceptual map of pedagogical content knowledge(PCK) of prospective and experienced teachers on inclusive education, and conduct a comparative analysis on the difference between the characteristics of the conceptual maps of each groups, in order to observe the knowledge conception and professionalism of the two groups on pedagogical content knowledge. To do so, the research used quota sampling, to extract the total sample of 60, which consisted 30 prospective and 30 experienced physical education teachers, each from the three regions of Seoul, Gyeonggi-do, and Chungcheongnam-do. For data analysis, independent t-test was conducted using the conceptual map method of Novak & Gowin(1984), and SPSS Win version 22.0. The findings are as follows: First, after analyzing the superordinate factors described in the conceptual map, it was found that the categories and the total number of superordinate concepts varied. Second, after analyzing the subordinate concepts identified in the conceptual map of the two groups, the categories and the total number of subordinate concepts differed between the two groups. Third, the characteristics of superordinate concepts encompassing both the depth and the degree of knowledge conception and professionalism, between the two groups, were not found to be significantly different, indicating that the difference of knowledge conception and professionalism of the two groups on inclusive education PCK. These findings are expected to contribute to the training of teachers in achieving a more practical inclusive education.
A direct mechanical nanomachining, tribo-nanolithography (TNL), has been developed to fabricate m... more A direct mechanical nanomachining, tribo-nanolithography (TNL), has been developed to fabricate micro mold on Si substrate in mechanical milling mode. An atomic force microscope (AFM) tip is replaced by a lab-made Si cantilever with a polycrystalline diamond (PCD) tool. Mechanical cutting by PCD tool enables simple fabrication of micro molds with several tens of nanometers depth. Machined cavities of the Si substrate are prepared as a master mold for additional micro molding using polydimethylsiloxane (PDMS). Micro cavities are successfully duplicated in positive patterns similar to soft lithography. Normal loads of cantilever and AFM topographical images are used to discuss micro mold and micro molding characteristics.
The purpose of this study is to evaluate the usefulness of computed tomography (CT) for spiral ti... more The purpose of this study is to evaluate the usefulness of computed tomography (CT) for spiral tibia shaft fracture by analyzing associated distal tibia intra-articular fractures diagnosed by CT only which met the indication of surgical fixation and were fixed. Materials and Methods: Ninety-five spiral tibia shaft fractures with preoperative ankle plain radiographs and CT were analyzed retrospectively. The incidence and type of associated distal tibia articular fractures were evaluated by reviewing ankle plain radiography and CT. The number of fractures diagnosed by CT that correspond with the indication of fixation and that were actually fixed were analyzed. Results: Among 95 spiral tibia shaft fractures, 62 cases (65.3%) were associated with distal tibia intra-articular fracture. There were 37 cases of posterior malleolar fracture, 5 cases of avulsion fracture of the distal anterior tibiofibular ligament, 5 cases of medial malleolar fracture, and 15 cases of complex fracture. Among 52 posterior malleolar fractures including complex fracture, 20 cases were diagnosed by ankle plain radiograph. Of these 20 cases, 16 posterior malleolar fractures (80.0%) met the indication of surgical fixation, and 14 cases were actually fixed with a screw. Among 32 posterior malleolar fractures diagnosed by CT only, 26 cases (81.3%) met the indication of surgical fixation and 18 cases (56.3%) were fixed by screw. Conclusion: Approximately 50% of associated fractures were diagnosed by CT only and more than 80% of associated posterior malleolar fractures met the indication of surgical fixation and among these fractures, 18 cases (56.3%) were actually fixed by screw. This result suggests that CT is useful in diagnosis and treatment of distal tibia intra-articular fracture associated with spiral tibia shaft fracture.
Journal of The Korea Institute of Healthcare Architecture, 2016
According to the trend of the global burden of disease, in the future our society is expected to ... more According to the trend of the global burden of disease, in the future our society is expected to face with gradually increasing problems related to mental health and the demand for the various types of quality mental health facilities. This study investigates whether the accreditation of Mental health facilities serves as a building evaluation tool, and contribute to environmental welfare of the mentally ill. Methods: The facility assessment items related to architectural design are extracted through the analysis about the accreditation program of KOIHA. Extracted items should review if they comply with the relevant regulations, and establish building design standard. Results: This study shows that the accreditation of KOIHA can certify psychiatric hospitals meet the legal requirements, the minimum standard of facilities. But it is not the evaluation of environmental quality. It is difficult to assess the quality of facility in terms of architectural design, because it has no specific standards or the level of assessment. Implications: The accreditation for mental health facilities should be able to provide the right and opportunity to choose a more quality facility for the customer. The introduction of a certification system for the evaluation of environmental quality is required in order to overcome the limitations of the accreditation of KOIHA. Development of design guidelines for mental health facilities that are the basis for certification should be also followed.
Journal of the Korean Society for Surgery of the Hand, 2016
The authors performed an autologous cancellous bone graft from the iliac crest and headless compr... more The authors performed an autologous cancellous bone graft from the iliac crest and headless compression screw fixation for the treatment of Mack-Lichtman type II scaphoid waist nonunion. The purpose of this study was to determine whether this procedure was effective in achieving bony union and restoration of alignment. Methods: We retrospectively reviewed medical records and radiographs of 30 patients who underwent a cancellous bone graft and headless compression screw fixation for scaphoid waist nonunion. There 28 men and 2 women with a mean age of 32.8 year-old (range, 21-63 year-old). The mean time to surgery from initial injury was 10 months (range, 3-25 months) and the average followup duration was 37.5 months (range, 15-52 months). The authors analyzed bony union, lateral intrascaphoid angle (LISA), scapholunate angle (SLA), radiolunate angle (RLA), and scaphoid length in radiographs and evaluated the modified Mayo wrist score (MMWS) as a functional outcome. Results: Bony union was achieved in all cases. In lateral plain X-ray, preoperative anatomic alignment including LISA, SLA, RLA, and scaphoid length was recovered at immediate postoperative measurement. Those alignment restoration was likely to maintain in final follow-up in despite of statistical difference. The wrist motion and the MMWS improved significantly at the last follow-up. Conclusion: A non-structural autologous cancellous bone graft from the iliac crest and headless screw fixation provided reliable results and can be one of the effective treatment options for patients with symptomatic Mack-Lichtman type II nonunion in the middle one-third of the scaphoid.
Melanomas are fast growing high-mortality tumors, and specific treatments for melanomas are neede... more Melanomas are fast growing high-mortality tumors, and specific treatments for melanomas are needed. Melanoma cells overexpress focal adhesion kinase (FAK) compared to normal keratinocytes, and we sought to exploit this difference to create a selectively lethal therapy. We combined gold nanoparticles (GNP) with antibodies targeting phosphorylated FAK (p-FAK). These conjugates (p-FAK-GNP) entered G361 melanoma cells and bound p-FAK. Treatment with p-FAK-GNP decreased the viability of G361 cells in a time dependent manner by inducing apoptosis. To maximize the preferential killing of G361 cells, non-thermal atmospheric pressure plasma was used to stimulate the GNP within p-FAK-GNP. Combined treatment with plasma and p-FAK-GNP showed much higher lethality against G361 cells than HaCaT keratinocyte cells. The p-FAK-GNP induced apoptosis over 48 hours in G361 cells, whereas plasma and p-FAK-GNP killed G361 cells immediately. This study demonstrates that combining plasma with p-FAK-GNP results in selective lethality against human melanoma cells.
The study aim was to evaluate gap healing after medial open-wedge high tibial osteotomy (MOWHTO) ... more The study aim was to evaluate gap healing after medial open-wedge high tibial osteotomy (MOWHTO) using novel injectable beta-tricalcium phosphate (β-TCP) as gap filler. We also aimed to evaluate radiographic and clinical outcome of MOWHTO using injectable β-TCP. Consecutive 28 patients underwent MOWHTO using anatomical locking plate fixation, and β-TCP was injected as gap filler. Serial radiographs and computed tomography were taken at postoperative 3 and 12 months, and gap healing was assessed. Lower extremity alignment was measured on radiographs, and clinical outcome was evaluated by determining International Knee Documentation Committee, Western Ontario and McMaster Universities Arthritis Index, and visual analogue scales for pain scores. Progress of bone union was found on plain radiographs, and the mean ratio (β-TCP/host bone) of computed tomography attenuation values significantly changed from postoperative 3 months to 12 months, which indicates maturation of β-TCP. The avera...
As outdoor activities participation increase, Achilles tendon rupture incidence also tends to inc... more As outdoor activities participation increase, Achilles tendon rupture incidence also tends to increase. There are a number of treatment and rehabilitation options for a ruptured Achilles tendon. However, the optimal rehabilitation protocols are still under debate. The purpose of this study is to determine whether early rehabilitation is more effective than conventional rehabilitation. Medical records of 56 patients who had been treated with open repair after a ruptured Achilles tendon were retrospectively reviewed. 24 patients were treated postoperatively with below knee cast immobilization for four weeks, and they started tolerable weight-bearing rehabilitation at four weeks' follow-up. The remaining 32 patients were managed postoperatively with short leg splint immobilization for two weeks and started the tolerable weight-bearing at two weeks' follow-up. We evaluated the patients several times to identify when the single heel raise was possible and measured the American Or...
Pulse electrochemical nanopatterning (PECN), a non-contact scanning probe lithography (NC-SPL) pr... more Pulse electrochemical nanopatterning (PECN), a non-contact scanning probe lithography (NC-SPL) process using ultrashort voltage pulses, is based primarily on an electrochemical machining (ECM) process using localized electrochemical oxidation between a sharp tool tip and the sample surface. In this study, nanoscale oxide patterns were formed on silicon Si (100) wafer surfaces via electrochemical surface nanopatterning, by supplying external pulsed currents through non-contact atomic force microscopy. Nanoscale oxide width and height were controlled by modulating the applied pulse duration. Additionally, protruding nanoscale oxides were removed completely by simple chemical etching, showing a depressed pattern on the sample substrate surface. Nanoscale two-dimensional oxides, prepared by a localized electrochemical reaction, can be defined easily by controlling physical and electrical variables, before proceeding further to a layer-by-layer nanofabrication process.
International Association for Development of the Information Society, 2015
Living conditions and social environment are changing through time, and recently schooling popula... more Living conditions and social environment are changing through time, and recently schooling population is diminishing in Korea. Thus the number of abandoned schools has increased. In order to utilize unused space a mechanism is required for the exchange of various ideas. However, there is little effort to provide a platform for this purpose. This study aims at developing a process and a systemic method to collect intelligence of utilizing unused space.
Recently, a variety of efforts have been taken to convey sustainable management strategies of spo... more Recently, a variety of efforts have been taken to convey sustainable management strategies of sports apparel brands through single-person media. However, there is a lack of theoretical information on the path that leads these corporate marketing activities to brand reliability and purchase intention of consumers. Therefore, this study aims to analyze the path through which the sustainable management strategy established by a sports apparel brand affects the brand awareness and reliability, as well as the purchase intention of consumers when experiencing this strategy through single-person media. The results are summarized as follows: Firstly, the sustainable management strategies of a sports apparel brand carried out through single-person media had statistically significant positive impacts on the benevolence reliability perceived by single-person media viewers. Secondly, benevolence also had a statistically significant positive impact on the consumers’ purchase intention. It is exp...
2018 IEEE International Conference on Consumer Electronics (ICCE), 2018
Due to the rapid increase in the production of portable digital audio devices and the continuous ... more Due to the rapid increase in the production of portable digital audio devices and the continuous upgrades to internet access speeds, the market for MQS(Mastering Quality Sound) audio is growing rapidly as the format possesses higher audio quality than MP3. Unlike MP3 or CD formats that result in loss of quality and resolution, MQS represents the original audio recording of the singer in the studio with no loss in audio quality, and utilizes lossless audio codecs for compression to maintain the highest quality. While the most commonly used lossless audio codec is FLAC, the compression rate of this codec is not effective, resulting in large file sizes and overhead when conventional DRM is applied. This paper presents a new DRM model that allows for low-quality previews and minimizes battery drain in smartphones. This model has already been implemented on the Android platform, and usability has been evaluated.
Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2017
Cartilage regeneration was found in 39 knees (70.0%) at the second-look arthroscopy. While BSS of... more Cartilage regeneration was found in 39 knees (70.0%) at the second-look arthroscopy. While BSS of the medial compartment was significantly decreased from 3.6 AE 1.5 to 1.4 AE 0.4 (p<0.01) after OWTHO, BSS of the lateral compartment did not change postoperatively. Postoperative BSS of the medial compartment significantly correlated with VAS, KOOS and WBLR. No statistical significant associations between BTU and cartilage regeneration were found. Conclusion: OWHTO led to a significant decrease in BTU of the medial compartment, which correlated well with knee pain and postoperative mechanical alignment. Despite shifting the weight bearing line to the lateral compartment, no increased postoperative BTU was found in the lateral compartment. This observation demonstrated that OWHTO does not cause overloading in the lateral compartment.
Background: The LDL receptor is a cell-surface protein that regulates plasma cholesterol by speci... more Background: The LDL receptor is a cell-surface protein that regulates plasma cholesterol by specific uptake of LDL particles from the blood circulation. Familial hypercholesterolemia (FH) results from defective catabolism of LDL, which is caused by mutations in the LDL-receptor gene.Methods: For the rapid and reliable detection of large rearrangements in the LDL-receptor gene, we established a screening method based on long-distance PCR as an alternative to Southern-blot hybridization. Using long-distance PCR, 45 unrelated Korean subjects heterozygous for FH were screened to assess the frequency and nature of major structural rearrangements in the LDL-receptor gene.Results: Two different deletion mutations, FH6 (same type as FH3 and FH311) and FH 32, were detected in four families by long-distance PCR. Detailed restriction mapping and sequence analysis showed that FH6 was a 5.71-kb deletion extending from intron 8 to intron 12 and that FH32 was a 2-kb deletion extending from intron ...
This research aimed to examine the conceptual map of pedagogical content knowledge(PCK) of prospe... more This research aimed to examine the conceptual map of pedagogical content knowledge(PCK) of prospective and experienced teachers on inclusive education, and conduct a comparative analysis on the difference between the characteristics of the conceptual maps of each groups, in order to observe the knowledge conception and professionalism of the two groups on pedagogical content knowledge. To do so, the research used quota sampling, to extract the total sample of 60, which consisted 30 prospective and 30 experienced physical education teachers, each from the three regions of Seoul, Gyeonggi-do, and Chungcheongnam-do. For data analysis, independent t-test was conducted using the conceptual map method of Novak & Gowin(1984), and SPSS Win version 22.0. The findings are as follows: First, after analyzing the superordinate factors described in the conceptual map, it was found that the categories and the total number of superordinate concepts varied. Second, after analyzing the subordinate concepts identified in the conceptual map of the two groups, the categories and the total number of subordinate concepts differed between the two groups. Third, the characteristics of superordinate concepts encompassing both the depth and the degree of knowledge conception and professionalism, between the two groups, were not found to be significantly different, indicating that the difference of knowledge conception and professionalism of the two groups on inclusive education PCK. These findings are expected to contribute to the training of teachers in achieving a more practical inclusive education.
A direct mechanical nanomachining, tribo-nanolithography (TNL), has been developed to fabricate m... more A direct mechanical nanomachining, tribo-nanolithography (TNL), has been developed to fabricate micro mold on Si substrate in mechanical milling mode. An atomic force microscope (AFM) tip is replaced by a lab-made Si cantilever with a polycrystalline diamond (PCD) tool. Mechanical cutting by PCD tool enables simple fabrication of micro molds with several tens of nanometers depth. Machined cavities of the Si substrate are prepared as a master mold for additional micro molding using polydimethylsiloxane (PDMS). Micro cavities are successfully duplicated in positive patterns similar to soft lithography. Normal loads of cantilever and AFM topographical images are used to discuss micro mold and micro molding characteristics.
The purpose of this study is to evaluate the usefulness of computed tomography (CT) for spiral ti... more The purpose of this study is to evaluate the usefulness of computed tomography (CT) for spiral tibia shaft fracture by analyzing associated distal tibia intra-articular fractures diagnosed by CT only which met the indication of surgical fixation and were fixed. Materials and Methods: Ninety-five spiral tibia shaft fractures with preoperative ankle plain radiographs and CT were analyzed retrospectively. The incidence and type of associated distal tibia articular fractures were evaluated by reviewing ankle plain radiography and CT. The number of fractures diagnosed by CT that correspond with the indication of fixation and that were actually fixed were analyzed. Results: Among 95 spiral tibia shaft fractures, 62 cases (65.3%) were associated with distal tibia intra-articular fracture. There were 37 cases of posterior malleolar fracture, 5 cases of avulsion fracture of the distal anterior tibiofibular ligament, 5 cases of medial malleolar fracture, and 15 cases of complex fracture. Among 52 posterior malleolar fractures including complex fracture, 20 cases were diagnosed by ankle plain radiograph. Of these 20 cases, 16 posterior malleolar fractures (80.0%) met the indication of surgical fixation, and 14 cases were actually fixed with a screw. Among 32 posterior malleolar fractures diagnosed by CT only, 26 cases (81.3%) met the indication of surgical fixation and 18 cases (56.3%) were fixed by screw. Conclusion: Approximately 50% of associated fractures were diagnosed by CT only and more than 80% of associated posterior malleolar fractures met the indication of surgical fixation and among these fractures, 18 cases (56.3%) were actually fixed by screw. This result suggests that CT is useful in diagnosis and treatment of distal tibia intra-articular fracture associated with spiral tibia shaft fracture.
Journal of The Korea Institute of Healthcare Architecture, 2016
According to the trend of the global burden of disease, in the future our society is expected to ... more According to the trend of the global burden of disease, in the future our society is expected to face with gradually increasing problems related to mental health and the demand for the various types of quality mental health facilities. This study investigates whether the accreditation of Mental health facilities serves as a building evaluation tool, and contribute to environmental welfare of the mentally ill. Methods: The facility assessment items related to architectural design are extracted through the analysis about the accreditation program of KOIHA. Extracted items should review if they comply with the relevant regulations, and establish building design standard. Results: This study shows that the accreditation of KOIHA can certify psychiatric hospitals meet the legal requirements, the minimum standard of facilities. But it is not the evaluation of environmental quality. It is difficult to assess the quality of facility in terms of architectural design, because it has no specific standards or the level of assessment. Implications: The accreditation for mental health facilities should be able to provide the right and opportunity to choose a more quality facility for the customer. The introduction of a certification system for the evaluation of environmental quality is required in order to overcome the limitations of the accreditation of KOIHA. Development of design guidelines for mental health facilities that are the basis for certification should be also followed.
Journal of the Korean Society for Surgery of the Hand, 2016
The authors performed an autologous cancellous bone graft from the iliac crest and headless compr... more The authors performed an autologous cancellous bone graft from the iliac crest and headless compression screw fixation for the treatment of Mack-Lichtman type II scaphoid waist nonunion. The purpose of this study was to determine whether this procedure was effective in achieving bony union and restoration of alignment. Methods: We retrospectively reviewed medical records and radiographs of 30 patients who underwent a cancellous bone graft and headless compression screw fixation for scaphoid waist nonunion. There 28 men and 2 women with a mean age of 32.8 year-old (range, 21-63 year-old). The mean time to surgery from initial injury was 10 months (range, 3-25 months) and the average followup duration was 37.5 months (range, 15-52 months). The authors analyzed bony union, lateral intrascaphoid angle (LISA), scapholunate angle (SLA), radiolunate angle (RLA), and scaphoid length in radiographs and evaluated the modified Mayo wrist score (MMWS) as a functional outcome. Results: Bony union was achieved in all cases. In lateral plain X-ray, preoperative anatomic alignment including LISA, SLA, RLA, and scaphoid length was recovered at immediate postoperative measurement. Those alignment restoration was likely to maintain in final follow-up in despite of statistical difference. The wrist motion and the MMWS improved significantly at the last follow-up. Conclusion: A non-structural autologous cancellous bone graft from the iliac crest and headless screw fixation provided reliable results and can be one of the effective treatment options for patients with symptomatic Mack-Lichtman type II nonunion in the middle one-third of the scaphoid.
Melanomas are fast growing high-mortality tumors, and specific treatments for melanomas are neede... more Melanomas are fast growing high-mortality tumors, and specific treatments for melanomas are needed. Melanoma cells overexpress focal adhesion kinase (FAK) compared to normal keratinocytes, and we sought to exploit this difference to create a selectively lethal therapy. We combined gold nanoparticles (GNP) with antibodies targeting phosphorylated FAK (p-FAK). These conjugates (p-FAK-GNP) entered G361 melanoma cells and bound p-FAK. Treatment with p-FAK-GNP decreased the viability of G361 cells in a time dependent manner by inducing apoptosis. To maximize the preferential killing of G361 cells, non-thermal atmospheric pressure plasma was used to stimulate the GNP within p-FAK-GNP. Combined treatment with plasma and p-FAK-GNP showed much higher lethality against G361 cells than HaCaT keratinocyte cells. The p-FAK-GNP induced apoptosis over 48 hours in G361 cells, whereas plasma and p-FAK-GNP killed G361 cells immediately. This study demonstrates that combining plasma with p-FAK-GNP results in selective lethality against human melanoma cells.
The study aim was to evaluate gap healing after medial open-wedge high tibial osteotomy (MOWHTO) ... more The study aim was to evaluate gap healing after medial open-wedge high tibial osteotomy (MOWHTO) using novel injectable beta-tricalcium phosphate (β-TCP) as gap filler. We also aimed to evaluate radiographic and clinical outcome of MOWHTO using injectable β-TCP. Consecutive 28 patients underwent MOWHTO using anatomical locking plate fixation, and β-TCP was injected as gap filler. Serial radiographs and computed tomography were taken at postoperative 3 and 12 months, and gap healing was assessed. Lower extremity alignment was measured on radiographs, and clinical outcome was evaluated by determining International Knee Documentation Committee, Western Ontario and McMaster Universities Arthritis Index, and visual analogue scales for pain scores. Progress of bone union was found on plain radiographs, and the mean ratio (β-TCP/host bone) of computed tomography attenuation values significantly changed from postoperative 3 months to 12 months, which indicates maturation of β-TCP. The avera...
As outdoor activities participation increase, Achilles tendon rupture incidence also tends to inc... more As outdoor activities participation increase, Achilles tendon rupture incidence also tends to increase. There are a number of treatment and rehabilitation options for a ruptured Achilles tendon. However, the optimal rehabilitation protocols are still under debate. The purpose of this study is to determine whether early rehabilitation is more effective than conventional rehabilitation. Medical records of 56 patients who had been treated with open repair after a ruptured Achilles tendon were retrospectively reviewed. 24 patients were treated postoperatively with below knee cast immobilization for four weeks, and they started tolerable weight-bearing rehabilitation at four weeks' follow-up. The remaining 32 patients were managed postoperatively with short leg splint immobilization for two weeks and started the tolerable weight-bearing at two weeks' follow-up. We evaluated the patients several times to identify when the single heel raise was possible and measured the American Or...
Pulse electrochemical nanopatterning (PECN), a non-contact scanning probe lithography (NC-SPL) pr... more Pulse electrochemical nanopatterning (PECN), a non-contact scanning probe lithography (NC-SPL) process using ultrashort voltage pulses, is based primarily on an electrochemical machining (ECM) process using localized electrochemical oxidation between a sharp tool tip and the sample surface. In this study, nanoscale oxide patterns were formed on silicon Si (100) wafer surfaces via electrochemical surface nanopatterning, by supplying external pulsed currents through non-contact atomic force microscopy. Nanoscale oxide width and height were controlled by modulating the applied pulse duration. Additionally, protruding nanoscale oxides were removed completely by simple chemical etching, showing a depressed pattern on the sample substrate surface. Nanoscale two-dimensional oxides, prepared by a localized electrochemical reaction, can be defined easily by controlling physical and electrical variables, before proceeding further to a layer-by-layer nanofabrication process.
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