Papers by Tiong Peng Yap
Vision research, Sep 1, 2024
Ophthalmic and physiological optics/Ophthalmic & physiological optics, Jun 16, 2024
BMJ Open, Sep 30, 2023
Introduction Ocular motor function is susceptible to neurological injury because it requires a la... more Introduction Ocular motor function is susceptible to neurological injury because it requires a large portion of brain circuitry including every lobe of the brain, brainstem, thalamus, basal ganglia, cerebellum, cranial nerves and visual tracts. While reports of a high frequency of ocular motor dysfunctions after mild traumatic brain injury (mTBI) span multidisciplinary journals, there is no scoping review of the signs, diagnostic assessments and criteria, and appropriate management of ocular motor disorders post-mTBI. Post-mTBI ocular motor dysfunction has been reported to respond to active treatment. The objective of this scoping review is to map the available evidence on the diagnostic assessment and treatment modalities currently used in the management of mTBI-related ocular motor disorders in children and adults. This scoping review also aims to identify gaps in the current literature and provide suggestions for future research. Methods and analysis This review will include populations with reported concussion and/or mTBI without restrictions on age, race, sex or time since injury. The review will evaluate the reported symptoms related to ocular motor dysfunction, types of assessments and diagnostic criteria used, reported treatments, and the level of evidence supporting the reported treatments. This review will exclude literature on brain injury of non-traumatic aetiology and moderate/severe traumatic brain injury. Ocular motor dysfunction after mTBI appears in journals across multiple disciplines. Thus, multiple databases will be evaluated including Pubmed, Embase, PEDro, OVID, Clinical Key, Google Scholar and REHABDATA. Literature will be searched from inception to present day. Evidence sources will include experimental study designs including randomised controlled trials, non-randomised controlled trials and interrupted time-series. Additionally, analytical observational studies including prospective and retrospective cohort studies, case series, crosssectional studies and clinical practice guidelines will be considered for inclusion. Data will be extracted on clinical presentation, frequency, assessment, diagnostic criteria management strategies and outcomes of concussion and mTBI-related ocular motor disorders. Ethics and dissemination This scoping review will use data from existing publications and does not require ethical approval by an institutional review board. Results will be disseminated through publication in a peerreviewed scientific journal and presented at relevant conferences and as part of future workshops with professionals involved with diagnosis and management of patients with mTBI.
Forensic Science International, 2019
Highlights New psychedelic phenethylamines emerged in illicit drugs market in recent years GC... more Highlights New psychedelic phenethylamines emerged in illicit drugs market in recent years GC-MS is not a suitable technique for analysis of thermally labile 25-NBOH drugs Alternative non-thermal technique has to be used to prevent mis-identification Simultaneous analysis of twelve phenethylamines and LSD using LC-MS/MS in 9 min
Optical treatment is the primary treatment of all types of amblyopia that has a refractive compon... more Optical treatment is the primary treatment of all types of amblyopia that has a refractive component. However, it is unclear how optical treatment impacts cortical processing in amblyopic children as some of them may readily improve letter recognition visual acuity (treatment responders) but others may not (treatment non-responders). The main aim was to investigate the electrophysiological and psychophysical effects of optical treatment in children who have been newly-diagnosed with amblyopia in comparison with normal maturation in non-amblyopic children. The secondary aim was to explore whether pattern onset-offset visual evoked potentials (POVEPs) and psychophysical grating acuities (GA) may be predictive of clinically significant improvements in letter recognition visual acuity (VA) after four months of optical treatment.The primary outcome measures were POVEP C3 amplitude and C3 latency and GA which were assessed in response to orientation-specific stimuli. The testing protocol ...
Advances in Ophthalmology and Optometry, 2020
Investigative Opthalmology & Visual Science, 2019
Investigative Ophthalmology & Visual Science, 2018
Investigative Ophthalmology & Visual Science, 2013
Investigative Ophthalmology & Visual Science, 2020
Investigative Ophthalmology & Visual Science, 2018
Documenta Ophthalmologica
Investigative Opthalmology & Visual Science
PURPOSE. We investigated and characterized the patterns of meridional anisotropies in newly diagn... more PURPOSE. We investigated and characterized the patterns of meridional anisotropies in newly diagnosed refractive amblyopes using pattern onset-offset visual evoked potentials (POVEPs) and psychophysical grating acuity (GA).
Yap et al Investigative Ophthalmology and Visual Science, 2020
PURPOSE. We investigated and characterized the patterns of meridional anisotropies in newly diagn... more PURPOSE. We investigated and characterized the patterns of meridional anisotropies in newly diagnosed refractive amblyopes using pattern onset-offset visual evoked potentials (POVEPs) and psychophysical grating acuity (GA).
American journal of …, 2011
• PURPOSE: To ascertain the health-related quality of life associated with symptomatic degenerati... more • PURPOSE: To ascertain the health-related quality of life associated with symptomatic degenerative vitreous floaters.
Conference Presentations by Tiong Peng Yap
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Papers by Tiong Peng Yap
Conference Presentations by Tiong Peng Yap