Papers by Stephanie Zamora
Journal of osteopathic medicine, Jul 1, 2017
patients with CTS. These findings create several avenues for future research. Specifically, the e... more patients with CTS. These findings create several avenues for future research. Specifically, the effect of osteopathic manipulative treatment on patients with CTS should be studied and compared with the effects of surgical procedures and multimodal manual therapy.
Journal of osteopathic medicine, May 1, 2018
One of these 2 studies noted that this finding was only observed in the group that received manip... more One of these 2 studies noted that this finding was only observed in the group that received manipulation followed by an exercise regimen, while no significant change was noted in the manipulation-only group. The study that evaluated pain catastrophizing found a significant association between pain sensitivity in patients who received spinal manual therapy (P<.02). Among the 7 studies assessing health-related quality of life, 5 found significant postintervention improvements (P<.001 to P<.043). Among the 4 trials reporting quality of life, 3 found significant improvements among the intervention groups (P<.001 to P<.05). The study was limited by the heterogeneous patient populations and overall poor quality of data reviewed. The pain conditions varied (ie, back pain, neck pain, shoulder pain), as did the age and sex of participants sampled. For example, among the UK BEAM, 1 Moustafa et al, 2 and Castro-Sanchez et al 3 trials, the mean age differed from 43 to 52.5 years, and the percentage of male participants ranged from 4.6% to 57%. Nevertheless, the results suggest that osteopathic interventions may positively affect the biopsychosocial factors related to patients with chronic pain. More work is needed to appraise outcomes, and standardized tools for biopsychosocial assessment should be integrated into all studies of osteopathic interventions and pain.
Journal of Humanistic Psychology, Jan 30, 2023
The COVID-19 pandemic has disproportionately impacted communities that are medically underserved ... more The COVID-19 pandemic has disproportionately impacted communities that are medically underserved across the United States, including the 6,700 Hispanic and Pascua Yaqui residents of Guadalupe, Arizona. In May 2020, Guadalupe experienced new COVID-19 cases at a rate 13.9 times as high as its surrounding county, urging town leadership to establish the Guadalupe Community Response Team (GCRT), a multisectoral network of community, academic, and public health partners. The objectives of the GCRT were to: (a) increase access to health and support services; (b) develop novel and intensive outreach efforts; and (c) build partnerships to strengthen public health capacity. From June 2020 to December 2021, the GCRT provided door-to-door case investigation and resource provision, coordinated testing and vaccination events, created public health communications, and developed COVID-19 guidance for cultural gatherings. These interventions were implemented in an effort to reduce community transmission of SARS-CoV-2 and increase equitable access to testing, vaccination, and social support resources. Cultural leaders, such as promotores de salud and Yaqui Cultural Specialists, were integral in building trust among community members. The GCRT provides valuable lessons learned on the importance of implementing a culturally grounded approach to COVID-19 mitigation to increase equitable access to health services during a public health emergency.
Journal of Humanistic Psychology
The COVID-19 pandemic has disproportionately impacted communities that are medically underserved ... more The COVID-19 pandemic has disproportionately impacted communities that are medically underserved across the United States, including the 6,700 Hispanic and Pascua Yaqui residents of Guadalupe, Arizona. In May 2020, Guadalupe experienced new COVID-19 cases at a rate 13.9 times as high as its surrounding county, urging town leadership to establish the Guadalupe Community Response Team (GCRT), a multisectoral network of community, academic, and public health partners. The objectives of the GCRT were to: (a) increase access to health and support services; (b) develop novel and intensive outreach efforts; and (c) build partnerships to strengthen public health capacity. From June 2020 to December 2021, the GCRT provided door-to-door case investigation and resource provision, coordinated testing and vaccination events, created public health communications, and developed COVID-19 guidance for cultural gatherings. These interventions were implemented in an effort to reduce community transmis...
International Journal of the Sociology of Language
Drawing on branded tweets that linguistically appropriate slang, African American Language, and h... more Drawing on branded tweets that linguistically appropriate slang, African American Language, and hip hop lyrics, this article examines how corporations rework black culture to create “corporate cool” as part of their advertising strategy on social media. We examine three processes that corporations engage in to associate themselves with “coolness” while managing levels of racial contact and proximity for their audience: 1) racially ambiguous voicing, 2) “bleaching” black bodies out of images, and 3) the forging of “racially tinged” intertextual connections. While previous scholarship has analyzed how acts of cultural and linguistic appropriation reap profit for white people and continue to stigmatize already racially marginalized groups, we describe how these seemingly innocent cultural and linguistic references harness a corporately constructed black cool to produce a sense of white comfort. We argue that white comfort is generated not only through the avoidance of overt references ...
Journal of Osteopathic Medicine, 2018
One of these 2 studies noted that this finding was only observed in the group that received manip... more One of these 2 studies noted that this finding was only observed in the group that received manipulation followed by an exercise regimen, while no significant change was noted in the manipulation-only group. The study that evaluated pain catastrophizing found a significant association between pain sensitivity in patients who received spinal manual therapy (P<.02). Among the 7 studies assessing health-related quality of life, 5 found significant postintervention improvements (P<.001 to P<.043). Among the 4 trials reporting quality of life, 3 found significant improvements among the intervention groups (P<.001 to P<.05). The study was limited by the heterogeneous patient populations and overall poor quality of data reviewed. The pain conditions varied (ie, back pain, neck pain, shoulder pain), as did the age and sex of participants sampled. For example, among the UK BEAM, 1 Moustafa et al, 2 and Castro-Sanchez et al 3 trials, the mean age differed from 43 to 52.5 years, and the percentage of male participants ranged from 4.6% to 57%. Nevertheless, the results suggest that osteopathic interventions may positively affect the biopsychosocial factors related to patients with chronic pain. More work is needed to appraise outcomes, and standardized tools for biopsychosocial assessment should be integrated into all studies of osteopathic interventions and pain.
Revista Estudios, 2016
The next investigation has the purpose of showing how the Universidad Nacional (UNA) through the ... more The next investigation has the purpose of showing how the Universidad Nacional (UNA) through the proyect called “Una nueva oportunidad” recognize as a human right the social reinsertion of the inmates, therefore it has as a general goal since 2015 and until now that is building mechanisms and techniques to contribute in the process of readaptability of the inmate population of the Centro de Atencion Institucional (CAI) de San Rafael de Alajuela. The final purpose of this document is to systematize the experience lived in the CAI all along the 2015 as the first year of intervention focus in analizing the partial goals gained in the module number one: “Construyendo mi historia de vida” , which pretends to generate , for the knowledge and recognition of the life stories of the prisioners that participate in the curse. Being part of action- participation methodology.
Journal of Osteopathic Medicine, 2017
patients with CTS. These findings create several avenues for future research. Specifically, the e... more patients with CTS. These findings create several avenues for future research. Specifically, the effect of osteopathic manipulative treatment on patients with CTS should be studied and compared with the effects of surgical procedures and multimodal manual therapy.
eLife, 2015
The bacteriophage population is large, dynamic, ancient, and genetically diverse. Limited genomic... more The bacteriophage population is large, dynamic, ancient, and genetically diverse. Limited genomic information shows that phage genomes are mosaic, and the genetic architecture of phage populations remains ill-defined. To understand the population structure of phages infecting a single host strain, we isolated, sequenced, and compared 627 phages of Mycobacterium smegmatis. Their genetic diversity is considerable, and there are 28 distinct genomic types (clusters) with related nucleotide sequences. However, amino acid sequence comparisons show pervasive genomic mosaicism, and quantification of inter-cluster and intra-cluster relatedness reveals a continuum of genetic diversity, albeit with uneven representation of different phages. Furthermore, rarefaction analysis shows that the mycobacteriophage population is not closed, and there is a constant influx of genes from other sources. Phage isolation and analysis was performed by a large consortium of academic institutions, illustrating ...
Cytotechnology, 2005
The development of specific catalytic inhibitors for the serine protease urokinase-type plasminog... more The development of specific catalytic inhibitors for the serine protease urokinase-type plasminogen activator (uPA) has been hindered due to difficulties in producing sufficient amounts of active recombinant uPA that is catalytically equivalent to native uPA. The purpose of this study was to develop an efficient system for the expression of recombinant human uPA that exhibits comparable proteolytic activity to that of the native protein. Since post-translational modifications (e.g. glycosylations) of uPA are necessary for efficient proteolytic activity, we have used a mammalian cell line [Chinese hamster ovary (CHO)-S] to express recombinant human uPA. CHO-S cells were selected to stably express full-length recombinant human uPA containing a hexahistidine tag at its C-terminus to permit purification by nickel-based affinity chromatography. Secretion of recombinant uPA into the culture media was confirmed by immunoblotting and the presence of an N-linked glycosylation was confirmed by PNGase sensitivity. Enzymatic activity of purified recombinant uPA was demonstrated using zymography and quantitatively compared to native uPA by kinetic analysis using an uPA-specific substrate. Native uPA and the recombinant uPA demonstrated comparable K m values (55.7 and 39 lM, respectively). Furthermore, inhibition studies using benzamidine resulted in a K i of 195 lM for native uPA, while recombinant uPA had a K i of 112 lM. These data indicate that recombinant human uPA expressed by CHO-S cells is functionally comparable to native uPA.
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Papers by Stephanie Zamora