Papers by Sree Pailot chanddra Roy
Bangabandhu Sheikh Mujib Medical University Journal, 2011
Choriocarcinoma is a malignant proliferation of syncytial trophoblast cells that do not form plac... more Choriocarcinoma is a malignant proliferation of syncytial trophoblast cells that do not form placental villi. Gestational choriocarcinoma may occur as a sequel to any type of human pregnancy. Choriocarcinoma is a rare trophoblastic tumor occured approximately 50% after term pregnancy, 25% after molar pregnancy and the remainder after other gestational events 1,2,3. Choriocarcinoma following a live term birth occurs in 1 per 50,000 births and it is associated with an unfavorable out come. In the majority of cases the choriocarcinoma present either as a growth in the uterus that fills up the uterine cavity or may perforate the uterine serosa. In some cases the primary foci may disappear and patient present with secondaries mainly in the vagina, lungs, brain or liver 4. If untreated, it is often swiftly fatal with distant metastasis. Post term gestational choriocarcinoma has a propensity for more extensive metastatic spread particularly in liver and brain and remission rate in patients to conventional chemotherapy is lower than other forms of Gestational Trophoblastic Disease (GTD) (Remision rate-61.5%) 2 .
Uploads
Papers by Sree Pailot chanddra Roy