Supplementary Table from Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinas... more Supplementary Table from Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinase Signaling Pathways and Inhibitors Define Its Role in Cell Migration
2021 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW), 2021
A face-swap deep fake replaces a person's face-from eyebrows to chin-with another face. A lip-syn... more A face-swap deep fake replaces a person's face-from eyebrows to chin-with another face. A lip-sync deep fake replaces a person's mouth region to be consistent with an impersonated or synthesized audio track. An overlooked aspect in the creation of these deep-fake videos is the human ear. Statically, the shape of the human ear has been shown to provide a biometric signal. Dynamically, movement of the mandible (lower jaw) causes changes in the shape of the ear and ear canal. While the facial identity in a faceswap deep fake may accurately depict the co-opted identity, the ears belong to the original identity. While the mouth in a lip-sync deep fake may be well synchronized with the audio, the dynamics of the ear motion will be de-coupled from the mouth and jaw motion. We describe a forensic technique that exploits these static and dynamic aural properties.
Aging is associated with increased production of reactive oxygen species (ROS) and oxidation-indu... more Aging is associated with increased production of reactive oxygen species (ROS) and oxidation-induced damage to intracellular structures and membranes. Caloric restriction (CR) has been demonstrated to delay aging in a variety of species. Although the mechanisms of CR remain to be clearly elucidated, reductions in oxidative damage have been shown to increase lifespan in several model systems. Contrary to the general belief that ROS production is reduced in CR, this article provides evidence that not only oxygen consumption but ROS production is enhanced in the calorie restricted condition. To understand the biological mechanism underlying the anti aging action of CR, the role of scavenging enzymes was studied. It was found that super oxide dismutase (SOD1 and SOD2), catalase and glutathione peroxidase (GPx) all are over expressed in CR. We further investigated the role of Sir2, a potential effector of CR response in the activation of scavenging enzymes. No marked difference was found in CR mediated activation of SOD and catalase in the absence of Sir2. Our results suggest that in CR scavenging enzymes are activated by a Sir2 independent manner.
To differentiate romantic disillusionment from similar constructs of dissatisfaction and regret, ... more To differentiate romantic disillusionment from similar constructs of dissatisfaction and regret, functional Magnetic Resonance Imaging (fMRI) data obtained when romantically involved individuals (N = 39) were reminded of relationship events representing these emotions were analyzed. Whole-brain activations suggested disillusionment-linked processes not observed for dissatisfaction or regret. Compared to dissatisfying events, disillusioning ones showed greater activity in regions pertaining to evaluation, reflection, and reconciling conflicting information (e.g., anterior cingulate cortex). No regions showed significantly more activation for dissatisfying than disillusioning events. Compared to regret-inducing events, disillusioning events showed greater activation in areas thought pertinent to detail processing and decision making (occipital fusiform and lingual gyrus). Regret-inducing events activated regions suggesting the planning and thoughts of how one could have acted differently (e.g., prefrontal cortex).
Supplementary Table from Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinas... more Supplementary Table from Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinase Signaling Pathways and Inhibitors Define Its Role in Cell Migration
2021 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW), 2021
A face-swap deep fake replaces a person's face-from eyebrows to chin-with another face. A lip-syn... more A face-swap deep fake replaces a person's face-from eyebrows to chin-with another face. A lip-sync deep fake replaces a person's mouth region to be consistent with an impersonated or synthesized audio track. An overlooked aspect in the creation of these deep-fake videos is the human ear. Statically, the shape of the human ear has been shown to provide a biometric signal. Dynamically, movement of the mandible (lower jaw) causes changes in the shape of the ear and ear canal. While the facial identity in a faceswap deep fake may accurately depict the co-opted identity, the ears belong to the original identity. While the mouth in a lip-sync deep fake may be well synchronized with the audio, the dynamics of the ear motion will be de-coupled from the mouth and jaw motion. We describe a forensic technique that exploits these static and dynamic aural properties.
Aging is associated with increased production of reactive oxygen species (ROS) and oxidation-indu... more Aging is associated with increased production of reactive oxygen species (ROS) and oxidation-induced damage to intracellular structures and membranes. Caloric restriction (CR) has been demonstrated to delay aging in a variety of species. Although the mechanisms of CR remain to be clearly elucidated, reductions in oxidative damage have been shown to increase lifespan in several model systems. Contrary to the general belief that ROS production is reduced in CR, this article provides evidence that not only oxygen consumption but ROS production is enhanced in the calorie restricted condition. To understand the biological mechanism underlying the anti aging action of CR, the role of scavenging enzymes was studied. It was found that super oxide dismutase (SOD1 and SOD2), catalase and glutathione peroxidase (GPx) all are over expressed in CR. We further investigated the role of Sir2, a potential effector of CR response in the activation of scavenging enzymes. No marked difference was found in CR mediated activation of SOD and catalase in the absence of Sir2. Our results suggest that in CR scavenging enzymes are activated by a Sir2 independent manner.
To differentiate romantic disillusionment from similar constructs of dissatisfaction and regret, ... more To differentiate romantic disillusionment from similar constructs of dissatisfaction and regret, functional Magnetic Resonance Imaging (fMRI) data obtained when romantically involved individuals (N = 39) were reminded of relationship events representing these emotions were analyzed. Whole-brain activations suggested disillusionment-linked processes not observed for dissatisfaction or regret. Compared to dissatisfying events, disillusioning ones showed greater activity in regions pertaining to evaluation, reflection, and reconciling conflicting information (e.g., anterior cingulate cortex). No regions showed significantly more activation for dissatisfying than disillusioning events. Compared to regret-inducing events, disillusioning events showed greater activation in areas thought pertinent to detail processing and decision making (occipital fusiform and lingual gyrus). Regret-inducing events activated regions suggesting the planning and thoughts of how one could have acted differently (e.g., prefrontal cortex).
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Papers by Shruti Agarwal