Ozet Amac. Bu arastirma tip 2 diabetes mellitus (DM) olgularinda odyometri ve isitsel beyin sapi ... more Ozet Amac. Bu arastirma tip 2 diabetes mellitus (DM) olgularinda odyometri ve isitsel beyin sapi yaniti testlerinin klinik onemini incelemek amaciyla yapildi. Yontem. Tip 2 DM tanisi konan 33’u kadin, 17’si erkek olmak uzere toplam 50 hasta ile ayni yas ve cinsiyetle eslestirilmis 50 kontrol grubu bireye kulak burun bogaz muayenesi yapildi; saf ses odyometri, yuksek frekans odyometrisi ve isitsel beyin sapi yanitlari testleri uygulandi. Calismada elde edilen verilerin istatiksel degerlendirmesi Fisher kesin ki-kare, ki-kare ve iki ortalama arasindaki farkin onemlilik testleri ile yapildi. Bulgular. Diabetik olgular ile kontrol grubunun isitsel beyin sapi yanitlari karsilastirildiginda I. dalga, III. dalga mutlak latanslarinda ve I-III interpeak latansta anlamli bir fark yok iken V. dalga mutlak latansinda ve III-V ile I-V interpeak latanslarda anlamli uzama saptandi. Sonuclar. Periferik iletim zamanini gosteren I. dalga mutlak latansinin normal, santral iletim zamanini gosteren V. d...
ABSTRACT Angiogenesis is a very essential process in tumor biology. Vascular endothelial growth f... more ABSTRACT Angiogenesis is a very essential process in tumor biology. Vascular endothelial growth factor (VEGF), angiopoietin and its receptor (TIE-2) are very important mediators for angiogenesis. In this trial, we aimed to analyze the role of these mediators on chemotherapy response and survival. Forty four cancer patients and 22 healthy controls were included in the study. Baseline serum samples were obtained from all participants and post-chemotherapy serum samples were obtained from the cancer patients. Serum vascular endothelial growth factor and TIE-2 levels were measured with quantitative enzyme-linked immunosorbent assay techniques. The baseline serum vascular endothelial growth factor level was 187.5 and 120.2 pg/ml in cancer patients and the control group (p = 0.006). The baseline serum TIE-2 level was 615.9 and 242.5 pg/ml in the patients and control group (p < 0.001). There was a significant difference between patients' baseline and post-chemotherapy VEGF levels (111.9 pg/ml; p < 0.001) and patients' baseline and post-chemotherapy TIE-2 levels (344.5 pg/ml; p < 0.001). The overall survival rate was better in patients who had lower baseline VEGF and TIE-2 levels and whose TIE-2 level had decreased with chemotherapy. Higher baseline TIE-2 and VEGF levels are related and worsen survival. Decreasing levels of TIE-2, but not VEGF, which, with chemotherapy, may be predictive for survival.
The aim of this study was to evaluate the morphological nasal changes associated with rapid maxil... more The aim of this study was to evaluate the morphological nasal changes associated with rapid maxillary expansion (RME) which is used in the treatment of skeletal maxillary narrowness. The study was performed with 20 patients 12 girls and 8 boys between the ages of 10 and 15 (13.4±0.99) and compared with a control group consisting of 16 subjects 10 girls and 6 boys between the ages of 10 and 15 (13.25±1.18). Lateral and anteroposterior radiographs were taken before RME (T1), after RME (T2) , and after retention (T3). Greater alar cartilage width, nasal cavity width, vertical and sagittal movement of the tip of nose, SNA° and nasolabial angle measurements were evaluated to understand the morphological and positional changes of the nose associated with RME. The results showed that the greater alar cartilage width returned to its original position, the nasal cavity width increased, and the tip of the nose moved downward and minimally forward; as well, SNA° returned to its original value and a small increase occurred in the nasolabial angle due to RME. Soft tissue changes may be considered clinically non-significant compared with the controls. RME did not affect the patients' frontal nasal appearance and mid-face soft tissue profile.
Epidermoid ve dermoid kistler vücudun çeşitli bölgelerinde görülebilen benign karakterli lezyonla... more Epidermoid ve dermoid kistler vücudun çeşitli bölgelerinde görülebilen benign karakterli lezyonlardır. Bu kistler oral kavitede %1,6 oranında görülürler ve oral kavite kistleri arasında oldukça nadir bir yer tutarlar. Ender görülen bu patolojilerden, sublingual yerleşimli dev epidermoid kist tanılı bir olgumuzu literatür bilgileri eşliğinde sunduk.
To evaluate the changes in nasal mucociliary clearance in orthodontic patients after rapid maxi... more To evaluate the changes in nasal mucociliary clearance in orthodontic patients after rapid maxillary expansion (RME) therapy. Forty-two children (25 boys and 17 girls) participated in this study. The RME group consisted of 21 patients (mean age, 13.8 years), who had undergone RME at the initiation of orthodontic treatment. The control group consisted of 21 subjects (mean age, 13.6 years), who were attending the department of orthodontics for active orthodontic treatment. The nasal mucociliary clearance was assessed by the saccharin test. Saccharin transit times (STTs) were measured for each treated subject before expansion (T1), after RME (T2), and after a 3-month retention period (T3). Records were obtained at the same time intervals for each group. The STT decreased significantly in the RME group after expansion and retention (P < .05). A statistically significant difference was found when the STTs of the control and RME groups were compared after expansion and retention ...
Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 2015
This study aims to investigate whether the time from the onset of symptoms to the start of treatm... more This study aims to investigate whether the time from the onset of symptoms to the start of treatment is a prognostic indicator in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). In this study, 96 patients (58 males, 38 females; mean age 37.8±2.5 years; range 16 to 67 years) who were diagnosed with ISSNHL in our clinic between January 1992 and April 2010 were retrospectively analyzed. All patients were treated with dextran 40 (rheomacrodex), pentoxifyllin, vitamin B complex and vitamin C regimen over 10 days with hospitalization and bed rest. The patients were tested by pure-tone audiometry. Audiograms were obtained on alternate days and at the end of the treatment. There was a complete recovery in 45 (60%) of 75 patients whose treatment was started in the first seven days, while a partial recovery was observed in 17 (22.66%) and no recovery was observed in 13 (17.33%). There was a complete recovery in two (9.52%) of 21 patients whose treatment was started after ...
Background/aim: Oxaliplatin is an effective and widely used chemotherapeutic agent in the treatme... more Background/aim: Oxaliplatin is an effective and widely used chemotherapeutic agent in the treatment of many solid tumors. The most common side effects are peripheral neuropathy, gastrointestinal toxicity, and neutropenia. There have been some case reports about ototoxicity with oxaliplatin, but no clinical trials. In this trial, we explored whether or not oxaliplatin has ototoxic effects. Materials and methods: A total of 18 patients, 14 with colorectal cancer and 4 with pancreatic cancer, were included in this study. Four patients (22%) were treated with a capecitabine and oxaliplatin (CapeOx) regimen, and 14 patients (78%) were treated with fluorouracil, leucovorin, and oxaliplatin (FOLFOX-6). Patients' pretreatment and posttreatment hearing levels were assessed with high-frequency audiometry and otoacoustic emission tests. Results: The median time between the first and the last oxaliplatin doses was 3.2 months (range: 2-7 months). There was no hearing loss in tests conducted for both ears of patients at frequencies
Archives of Otolaryngology–Head & Neck Surgery, 2004
From 1977 to 2001, 5 patients were seen with giant angiofibromas that had intracranial penetratio... more From 1977 to 2001, 5 patients were seen with giant angiofibromas that had intracranial penetration. Three of these had involvement of the cavernous sinus with angiographic evidence of significant blood supply to the tumor. We attempted complete tumor removal in all patients via a skull-base procedure. The infratemporal fossa/middle fossa approach was used in 3 patients, an anterior craniofacial approach in 1, and an anterior subcranial approach in 1. Complete tumor removal was achieved in 4 patients and incomplete excision in 1. The latter was attempted with an anterior subcranial approach but required an infratemporal fossa/middle fossa approach for completion because of unanticipated cavernous sinus involvement. The patient declined further surgery. This was the only patient who had persistent disease. Preoperative and intraoperative management, blood loss, complications, and residual effects are described.
Konjenital aural atrezi (KAA) kulak kepcesi, dis kulak yolu ve orta kulak deformitelerini icine a... more Konjenital aural atrezi (KAA) kulak kepcesi, dis kulak yolu ve orta kulak deformitelerini icine alan gelisimsel bir anomalidir. Dis kulak yolunda darlik veya atrezi olan olgularda otoskopik muayene de mumkun degildir. Bu yuzden bu olgularin degerlendirilmesinde yuksek rezolusyonlu bilgisayarli tomografi (YRBT) tetkiki onemli bir secenektir. Bu tetkik cerrahiyi planlamada ve operasyon icin uygun adaylarin belirlenmesinde de yol gosterici olabilir. Sunulan membranoz aural atrezili bu olguda YRBT'nin onemini vurgulamak istedik.
In this study, we have investigated the effect of nasal septal deviation (NSD) on nasal mucocilia... more In this study, we have investigated the effect of nasal septal deviation (NSD) on nasal mucociliary activity and how does a septoplasty operation affecs the nasal mucociliary transport rate in the first and third months during the post-operative period. Twenty-two patients who were diagnosed with NSD and 22 healthy controls were studied using rhinoscintigraphy with Tc-99m-macroaggregated albumin (Tc-99m-MAA). On each case, the nasal mucociliary transport rate (NMTR) was measured preoperatively only on five cases, on the first and third months of post-operative period. The NMTRs of patients with a deviated septum were significantly lower than the NMTRs of the healthy controls on both the convex and concave sides. Significant improvement was observed in the first post-operative month. On the concave and convex sides, the average postop third month post-operative NMTR value was higher than the first month post-operative NMTR values. It was concluded that the septoplasty operation improves reduced NMTRs after surgery. The effect of nasal surgery on nasal mucociliary activity may be more accurately evaluated in the third month than the first month of post-operative period.
The purpose of this study was to quantify peripheral eosinophil count and percentage of eosinophi... more The purpose of this study was to quantify peripheral eosinophil count and percentage of eosinophils in white blood cell (WBC) count of the patients with chronic rhinosinusitis (CRS) and look for the correlation between the CT scores and peripheral eosinophilia. Peripheral eosinophil counts and the percentages of eosinophils in white blood cell count (WBC) were statistically compared with CT scores in chronic rhinosinusitis (CRS) patients. We also statistically analyzed the peripheral eosinophil counts and the percentages of eosinophils in WBC counts between CRS patients and healthy ones. We found significant difference between CRS group and control group for peripheral eosinophil count, and percentage of eosinophils in WBC count (p=0.001 and p<0.001) respectively. We observed no correlation between CT scores and both peripheral eosinophil counts, or percentages of eosinophils in WBC counts (p=0.067and p=0.051) respectively. Although eosinophil seems as the dominator cell of CRS patients in the periphery, peripheral eosinophilia does not correlate with CT scores.
İnferior konka bülloza, alt konkanın pnömatizasyonu olup seyrek görülen bir klinik durumdur. Bu y... more İnferior konka bülloza, alt konkanın pnömatizasyonu olup seyrek görülen bir klinik durumdur. Bu yazıda burun tıkanıklığı ve aralıklı baş ağrısı yakınmasıyla başvuran 37 yaşındaki kadın inferior konka bülloza olgusu sunulmuştur. İnferior konka büllozanın semptomatolojisi, tanı ve tedavi stratejileri tartışılmıştır. Alt konka hipertrofisi ayırıcı tanısında inferior konka bülloza akılda tutulmalıdır.
ABSTRACT Pleomorphic adenoma is the most common neoplasm of the parotid gland This study was carr... more ABSTRACT Pleomorphic adenoma is the most common neoplasm of the parotid gland This study was carried out to evaluate tumor recurrence following extracapsular dissection of pleomorphic adenomas of the parotid gland. Previous studies have shown that extracapsular dissection (ECD) is an alternative approach to superficial parotidectomy (SP) for pleomorphic adenoma parotid tumours, associated with low recurrence rates equal to those following SP, but with significantly reduced morbidity. We conducted a retrospective evaluation and clinical follow-up of the patients who underwent extracapsular dissection of a pleomorphic adenoma as primary surgery in the otolaryngologic department of the Cumhuriyet University Clinics during the period from 2004 to 2012. 25 (89.3%) of 28 patients in the study were applied SP technique and 3 (10.7%) of them were applied ECD technique and no recurrence was detected. This study demonstrates that Extracapsular dissection is a viable alternative to superficial parotidectomy for the majority of parotid pleomorphic adenomas, associated with reduced morbidity. INTRODUCTİON Parotid neoplasia are relatively frequent, representing approximately 2 % of all tumors in the neck/facial area (De Campora, 1996). The pleomorphic adenoma shows a varying incidence of between 60.6% to 76.2% with respect to other parotid neoformations3 and in general occurs between the second and fourth decades of life, more often in the female sex (M / F ratio = 1 / 1.4) (Laccourreye et al., 1994). It is a benign tumor composed of epithelial and
Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 2008
Rhinophyma is a benign disease of the nasal skin causing cosmetic and functional disturbances. It... more Rhinophyma is a benign disease of the nasal skin causing cosmetic and functional disturbances. Its etiology remains uncertain. Surgery is the most common treatment of choice. A 55-year-old man with severe rhinophyma was treated with total excision of the involved tissue and sebaceous glands, and the defect was reconstructed with full-thickness skin graft. No recurrence was seen during a two-year follow-up period, and cosmetic and functional outcome was satisfactory.
Chronic otitis media (COM) is defined as persistent infection or inflammation of the middle ear a... more Chronic otitis media (COM) is defined as persistent infection or inflammation of the middle ear and mastoid air cells. The proximity of the middle ear cleft and mastoid air cells to the intratemporal and intracranial compartments places structures located in these areas at increased risk of infectious complications. The complications of COM are divided into intracranial and extracranial complications. The development and appropriate use of antibiotics have led to a decrease in these potentially devastating complications. However, they continue to occur, and clinical vigilance is required for early detection and treatment. We reported a case with multiple complications, both intracranial and extracranial secondary to COM.
Parapharyngeal space tumors are rare, accounting for 0.5% of head and neck neoplasms. Most of the... more Parapharyngeal space tumors are rare, accounting for 0.5% of head and neck neoplasms. Most of them are benign and originate in the salivary glands, especially the pleomorphic adenoma. We presented a 47-year-old male with parotid tail pleomorphic adenoma extending to the parapharyngeal space. The patient applied to our clinic with the complaints of a painless mass on his neck and in his mouth for three months. After fine needle aspiration biopsy the mass was diagnosed as pleomorphic adenoma. The patient hospitalized and operated in our clinic. As we see in literature review parapharyngeal space tumors are rare and most of them are pleomorphic adenomas arising from deep lobe of the parotid gland and extend into the PPS.
Ozet Amac. Bu arastirma tip 2 diabetes mellitus (DM) olgularinda odyometri ve isitsel beyin sapi ... more Ozet Amac. Bu arastirma tip 2 diabetes mellitus (DM) olgularinda odyometri ve isitsel beyin sapi yaniti testlerinin klinik onemini incelemek amaciyla yapildi. Yontem. Tip 2 DM tanisi konan 33’u kadin, 17’si erkek olmak uzere toplam 50 hasta ile ayni yas ve cinsiyetle eslestirilmis 50 kontrol grubu bireye kulak burun bogaz muayenesi yapildi; saf ses odyometri, yuksek frekans odyometrisi ve isitsel beyin sapi yanitlari testleri uygulandi. Calismada elde edilen verilerin istatiksel degerlendirmesi Fisher kesin ki-kare, ki-kare ve iki ortalama arasindaki farkin onemlilik testleri ile yapildi. Bulgular. Diabetik olgular ile kontrol grubunun isitsel beyin sapi yanitlari karsilastirildiginda I. dalga, III. dalga mutlak latanslarinda ve I-III interpeak latansta anlamli bir fark yok iken V. dalga mutlak latansinda ve III-V ile I-V interpeak latanslarda anlamli uzama saptandi. Sonuclar. Periferik iletim zamanini gosteren I. dalga mutlak latansinin normal, santral iletim zamanini gosteren V. d...
ABSTRACT Angiogenesis is a very essential process in tumor biology. Vascular endothelial growth f... more ABSTRACT Angiogenesis is a very essential process in tumor biology. Vascular endothelial growth factor (VEGF), angiopoietin and its receptor (TIE-2) are very important mediators for angiogenesis. In this trial, we aimed to analyze the role of these mediators on chemotherapy response and survival. Forty four cancer patients and 22 healthy controls were included in the study. Baseline serum samples were obtained from all participants and post-chemotherapy serum samples were obtained from the cancer patients. Serum vascular endothelial growth factor and TIE-2 levels were measured with quantitative enzyme-linked immunosorbent assay techniques. The baseline serum vascular endothelial growth factor level was 187.5 and 120.2 pg/ml in cancer patients and the control group (p = 0.006). The baseline serum TIE-2 level was 615.9 and 242.5 pg/ml in the patients and control group (p &amp;lt; 0.001). There was a significant difference between patients&amp;#39; baseline and post-chemotherapy VEGF levels (111.9 pg/ml; p &amp;lt; 0.001) and patients&amp;#39; baseline and post-chemotherapy TIE-2 levels (344.5 pg/ml; p &amp;lt; 0.001). The overall survival rate was better in patients who had lower baseline VEGF and TIE-2 levels and whose TIE-2 level had decreased with chemotherapy. Higher baseline TIE-2 and VEGF levels are related and worsen survival. Decreasing levels of TIE-2, but not VEGF, which, with chemotherapy, may be predictive for survival.
The aim of this study was to evaluate the morphological nasal changes associated with rapid maxil... more The aim of this study was to evaluate the morphological nasal changes associated with rapid maxillary expansion (RME) which is used in the treatment of skeletal maxillary narrowness. The study was performed with 20 patients 12 girls and 8 boys between the ages of 10 and 15 (13.4±0.99) and compared with a control group consisting of 16 subjects 10 girls and 6 boys between the ages of 10 and 15 (13.25±1.18). Lateral and anteroposterior radiographs were taken before RME (T1), after RME (T2) , and after retention (T3). Greater alar cartilage width, nasal cavity width, vertical and sagittal movement of the tip of nose, SNA° and nasolabial angle measurements were evaluated to understand the morphological and positional changes of the nose associated with RME. The results showed that the greater alar cartilage width returned to its original position, the nasal cavity width increased, and the tip of the nose moved downward and minimally forward; as well, SNA° returned to its original value and a small increase occurred in the nasolabial angle due to RME. Soft tissue changes may be considered clinically non-significant compared with the controls. RME did not affect the patients' frontal nasal appearance and mid-face soft tissue profile.
Epidermoid ve dermoid kistler vücudun çeşitli bölgelerinde görülebilen benign karakterli lezyonla... more Epidermoid ve dermoid kistler vücudun çeşitli bölgelerinde görülebilen benign karakterli lezyonlardır. Bu kistler oral kavitede %1,6 oranında görülürler ve oral kavite kistleri arasında oldukça nadir bir yer tutarlar. Ender görülen bu patolojilerden, sublingual yerleşimli dev epidermoid kist tanılı bir olgumuzu literatür bilgileri eşliğinde sunduk.
To evaluate the changes in nasal mucociliary clearance in orthodontic patients after rapid maxi... more To evaluate the changes in nasal mucociliary clearance in orthodontic patients after rapid maxillary expansion (RME) therapy. Forty-two children (25 boys and 17 girls) participated in this study. The RME group consisted of 21 patients (mean age, 13.8 years), who had undergone RME at the initiation of orthodontic treatment. The control group consisted of 21 subjects (mean age, 13.6 years), who were attending the department of orthodontics for active orthodontic treatment. The nasal mucociliary clearance was assessed by the saccharin test. Saccharin transit times (STTs) were measured for each treated subject before expansion (T1), after RME (T2), and after a 3-month retention period (T3). Records were obtained at the same time intervals for each group. The STT decreased significantly in the RME group after expansion and retention (P < .05). A statistically significant difference was found when the STTs of the control and RME groups were compared after expansion and retention ...
Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 2015
This study aims to investigate whether the time from the onset of symptoms to the start of treatm... more This study aims to investigate whether the time from the onset of symptoms to the start of treatment is a prognostic indicator in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). In this study, 96 patients (58 males, 38 females; mean age 37.8±2.5 years; range 16 to 67 years) who were diagnosed with ISSNHL in our clinic between January 1992 and April 2010 were retrospectively analyzed. All patients were treated with dextran 40 (rheomacrodex), pentoxifyllin, vitamin B complex and vitamin C regimen over 10 days with hospitalization and bed rest. The patients were tested by pure-tone audiometry. Audiograms were obtained on alternate days and at the end of the treatment. There was a complete recovery in 45 (60%) of 75 patients whose treatment was started in the first seven days, while a partial recovery was observed in 17 (22.66%) and no recovery was observed in 13 (17.33%). There was a complete recovery in two (9.52%) of 21 patients whose treatment was started after ...
Background/aim: Oxaliplatin is an effective and widely used chemotherapeutic agent in the treatme... more Background/aim: Oxaliplatin is an effective and widely used chemotherapeutic agent in the treatment of many solid tumors. The most common side effects are peripheral neuropathy, gastrointestinal toxicity, and neutropenia. There have been some case reports about ototoxicity with oxaliplatin, but no clinical trials. In this trial, we explored whether or not oxaliplatin has ototoxic effects. Materials and methods: A total of 18 patients, 14 with colorectal cancer and 4 with pancreatic cancer, were included in this study. Four patients (22%) were treated with a capecitabine and oxaliplatin (CapeOx) regimen, and 14 patients (78%) were treated with fluorouracil, leucovorin, and oxaliplatin (FOLFOX-6). Patients' pretreatment and posttreatment hearing levels were assessed with high-frequency audiometry and otoacoustic emission tests. Results: The median time between the first and the last oxaliplatin doses was 3.2 months (range: 2-7 months). There was no hearing loss in tests conducted for both ears of patients at frequencies
Archives of Otolaryngology–Head & Neck Surgery, 2004
From 1977 to 2001, 5 patients were seen with giant angiofibromas that had intracranial penetratio... more From 1977 to 2001, 5 patients were seen with giant angiofibromas that had intracranial penetration. Three of these had involvement of the cavernous sinus with angiographic evidence of significant blood supply to the tumor. We attempted complete tumor removal in all patients via a skull-base procedure. The infratemporal fossa/middle fossa approach was used in 3 patients, an anterior craniofacial approach in 1, and an anterior subcranial approach in 1. Complete tumor removal was achieved in 4 patients and incomplete excision in 1. The latter was attempted with an anterior subcranial approach but required an infratemporal fossa/middle fossa approach for completion because of unanticipated cavernous sinus involvement. The patient declined further surgery. This was the only patient who had persistent disease. Preoperative and intraoperative management, blood loss, complications, and residual effects are described.
Konjenital aural atrezi (KAA) kulak kepcesi, dis kulak yolu ve orta kulak deformitelerini icine a... more Konjenital aural atrezi (KAA) kulak kepcesi, dis kulak yolu ve orta kulak deformitelerini icine alan gelisimsel bir anomalidir. Dis kulak yolunda darlik veya atrezi olan olgularda otoskopik muayene de mumkun degildir. Bu yuzden bu olgularin degerlendirilmesinde yuksek rezolusyonlu bilgisayarli tomografi (YRBT) tetkiki onemli bir secenektir. Bu tetkik cerrahiyi planlamada ve operasyon icin uygun adaylarin belirlenmesinde de yol gosterici olabilir. Sunulan membranoz aural atrezili bu olguda YRBT'nin onemini vurgulamak istedik.
In this study, we have investigated the effect of nasal septal deviation (NSD) on nasal mucocilia... more In this study, we have investigated the effect of nasal septal deviation (NSD) on nasal mucociliary activity and how does a septoplasty operation affecs the nasal mucociliary transport rate in the first and third months during the post-operative period. Twenty-two patients who were diagnosed with NSD and 22 healthy controls were studied using rhinoscintigraphy with Tc-99m-macroaggregated albumin (Tc-99m-MAA). On each case, the nasal mucociliary transport rate (NMTR) was measured preoperatively only on five cases, on the first and third months of post-operative period. The NMTRs of patients with a deviated septum were significantly lower than the NMTRs of the healthy controls on both the convex and concave sides. Significant improvement was observed in the first post-operative month. On the concave and convex sides, the average postop third month post-operative NMTR value was higher than the first month post-operative NMTR values. It was concluded that the septoplasty operation improves reduced NMTRs after surgery. The effect of nasal surgery on nasal mucociliary activity may be more accurately evaluated in the third month than the first month of post-operative period.
The purpose of this study was to quantify peripheral eosinophil count and percentage of eosinophi... more The purpose of this study was to quantify peripheral eosinophil count and percentage of eosinophils in white blood cell (WBC) count of the patients with chronic rhinosinusitis (CRS) and look for the correlation between the CT scores and peripheral eosinophilia. Peripheral eosinophil counts and the percentages of eosinophils in white blood cell count (WBC) were statistically compared with CT scores in chronic rhinosinusitis (CRS) patients. We also statistically analyzed the peripheral eosinophil counts and the percentages of eosinophils in WBC counts between CRS patients and healthy ones. We found significant difference between CRS group and control group for peripheral eosinophil count, and percentage of eosinophils in WBC count (p=0.001 and p<0.001) respectively. We observed no correlation between CT scores and both peripheral eosinophil counts, or percentages of eosinophils in WBC counts (p=0.067and p=0.051) respectively. Although eosinophil seems as the dominator cell of CRS patients in the periphery, peripheral eosinophilia does not correlate with CT scores.
İnferior konka bülloza, alt konkanın pnömatizasyonu olup seyrek görülen bir klinik durumdur. Bu y... more İnferior konka bülloza, alt konkanın pnömatizasyonu olup seyrek görülen bir klinik durumdur. Bu yazıda burun tıkanıklığı ve aralıklı baş ağrısı yakınmasıyla başvuran 37 yaşındaki kadın inferior konka bülloza olgusu sunulmuştur. İnferior konka büllozanın semptomatolojisi, tanı ve tedavi stratejileri tartışılmıştır. Alt konka hipertrofisi ayırıcı tanısında inferior konka bülloza akılda tutulmalıdır.
ABSTRACT Pleomorphic adenoma is the most common neoplasm of the parotid gland This study was carr... more ABSTRACT Pleomorphic adenoma is the most common neoplasm of the parotid gland This study was carried out to evaluate tumor recurrence following extracapsular dissection of pleomorphic adenomas of the parotid gland. Previous studies have shown that extracapsular dissection (ECD) is an alternative approach to superficial parotidectomy (SP) for pleomorphic adenoma parotid tumours, associated with low recurrence rates equal to those following SP, but with significantly reduced morbidity. We conducted a retrospective evaluation and clinical follow-up of the patients who underwent extracapsular dissection of a pleomorphic adenoma as primary surgery in the otolaryngologic department of the Cumhuriyet University Clinics during the period from 2004 to 2012. 25 (89.3%) of 28 patients in the study were applied SP technique and 3 (10.7%) of them were applied ECD technique and no recurrence was detected. This study demonstrates that Extracapsular dissection is a viable alternative to superficial parotidectomy for the majority of parotid pleomorphic adenomas, associated with reduced morbidity. INTRODUCTİON Parotid neoplasia are relatively frequent, representing approximately 2 % of all tumors in the neck/facial area (De Campora, 1996). The pleomorphic adenoma shows a varying incidence of between 60.6% to 76.2% with respect to other parotid neoformations3 and in general occurs between the second and fourth decades of life, more often in the female sex (M / F ratio = 1 / 1.4) (Laccourreye et al., 1994). It is a benign tumor composed of epithelial and
Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 2008
Rhinophyma is a benign disease of the nasal skin causing cosmetic and functional disturbances. It... more Rhinophyma is a benign disease of the nasal skin causing cosmetic and functional disturbances. Its etiology remains uncertain. Surgery is the most common treatment of choice. A 55-year-old man with severe rhinophyma was treated with total excision of the involved tissue and sebaceous glands, and the defect was reconstructed with full-thickness skin graft. No recurrence was seen during a two-year follow-up period, and cosmetic and functional outcome was satisfactory.
Chronic otitis media (COM) is defined as persistent infection or inflammation of the middle ear a... more Chronic otitis media (COM) is defined as persistent infection or inflammation of the middle ear and mastoid air cells. The proximity of the middle ear cleft and mastoid air cells to the intratemporal and intracranial compartments places structures located in these areas at increased risk of infectious complications. The complications of COM are divided into intracranial and extracranial complications. The development and appropriate use of antibiotics have led to a decrease in these potentially devastating complications. However, they continue to occur, and clinical vigilance is required for early detection and treatment. We reported a case with multiple complications, both intracranial and extracranial secondary to COM.
Parapharyngeal space tumors are rare, accounting for 0.5% of head and neck neoplasms. Most of the... more Parapharyngeal space tumors are rare, accounting for 0.5% of head and neck neoplasms. Most of them are benign and originate in the salivary glands, especially the pleomorphic adenoma. We presented a 47-year-old male with parotid tail pleomorphic adenoma extending to the parapharyngeal space. The patient applied to our clinic with the complaints of a painless mass on his neck and in his mouth for three months. After fine needle aspiration biopsy the mass was diagnosed as pleomorphic adenoma. The patient hospitalized and operated in our clinic. As we see in literature review parapharyngeal space tumors are rare and most of them are pleomorphic adenomas arising from deep lobe of the parotid gland and extend into the PPS.
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