Papers by Jose Carlos Rivas
El proposito de este estudio fue determinar el inventario tecnologico en explotaciones ovinas lec... more El proposito de este estudio fue determinar el inventario tecnologico en explotaciones ovinas lecheras y su asociacion con las caracteristicas productivas y sociales del sistema. Participaron en este estudio 157 explotaciones. Se empleo estadistica descriptiva y un modelo lineal generalizado para estudiar el efecto de las variables sociales sobre la adopcion de tecnologias y la produccion de leche. Se evaluo la correlacion de Spearman entre el total de tecnologias y la produccion mas el efecto del total de tecnologias sobre la produccion de leche. Se identificaron 38 tecnologias con un rango de adopcion del 5 al 100%. La adopcion de tecnologias depende (P < 0,05) del nivel de educacion, esperanza de continuidad en la actividad, la figura juridica, dimension y la tenencia de tierra; respuesta no observada en produccion de leche. Se comprueba la asociacion ( P <0,01) entre el total de tecnologias y la produccion, donde la produccion de leche se incrementa a mayor numero de tecno...
Nutrients, 2020
In recent years, bacterial probiotic dietary supplementation has emerged as a promising way to im... more In recent years, bacterial probiotic dietary supplementation has emerged as a promising way to improve cognition and to alleviate stress and anxiety; however, yeast probiotics have not been tested. The aim of the present study was to determine whether 30-day supplementation with Saccharomyces boulardii enhances academic performance under stress and affects stress markers. The trial was retrospectively registered at clinicaltrials.gov (NCT03427515). Healthy medical students were randomized to supplement their diet with Saccharomyces boulardii CNCM I-1079 or placebo before sitting for an academic examination, which served as a model of stress. The grades of a final examination adjusted to subject knowledge tested in non-stressful conditions was used as a primary outcome measure. Psychometrically evaluated state anxiety, cortisol and metanephrine salivary levels, and pulse rate were tested at a non-stressful time point before the intervention as well as just before the stressor. Fifty ...
Journal of Microbiology & Experimentation, 2019
Introduction: Urinary tract infections (UTI) are one of the most frequent infectious processes wo... more Introduction: Urinary tract infections (UTI) are one of the most frequent infectious processes worldwide. The estimated incidence of UTI in our country is currently unknown. The treatment will depend on the age, the sex, the isolated germ, among others. Fluoroquinolones have been considered as the ideal treatment in this infection. The most empirically used is ciprofloxacin; however, its resistance makes a marked decrease in the effectiveness of the treatment with this agent. Objective: To describe the microbial resistance to ciprofloxacin in UTI as first-line treatment. Methods: Descriptive, cross-sectional and retrospective study, through the review of clinical records of 217 patients, who had the diagnosis of UTI, with reported cultures, during the period January 2013 to December 2017. Results: 82 patients were included (37.76%). The main germs that reported resistance were Escherichia coli (54.23%), Pseudomonas aeruginosa (11.86%). The most frequent comorbidity was Diabetes Mellitus. And the bacterial resistance reported in this study is 79.66%. Discussion: Resistance to ciprofloxacin constitutes a serious public health problem due to its frequent use. E coli were the bacterium with the greatest resistance to this antibiotic, superior to the reviewed studies. The proportion of resistance exceeds that reported in other works. Conclusion: Resistance to ciprofloxacin in urinary tract infection caused by common uropathogens is increasing. The use of this antibiotic agent as empirical therapy for UTI should be reconsidered and efforts should be made to limit its use to clinical conditions that warrant it.
ACS Applied Materials & Interfaces, 2019
A tricatalytic compartmentalized system that immobilizes metallic species to perform one-pot sequ... more A tricatalytic compartmentalized system that immobilizes metallic species to perform one-pot sequential functionalization is described: a three-dimensional (3D)-printed palladium monolith, ferritic copper(I) magnetic nanoparticles, and a 3D-printed polypropylene capsule-containing copper(II) loaded onto polystyrene-supported 1,5,7-triazabicyclo[4.4.0]dec-5-ene (PS-TBD) allowed the rapid synthesis of diverse substituted 1-([1,1'-biphenyl]-4-yl)-1 H-1,2,3-triazoles. The procedure is based on the Chan-Lam azidation/copper alkyne-azide cycloaddition/Suzuki reaction strategy in the solution phase. This catalytic system enabled the efficient assembly of the final compounds in high yields without the need for special additives or intermediate isolation. The monolithic catalyst-containing immobilized palladium species was synthesized by surface chemical modification of a 3D-printed silica monolith using a soluble polyimide resin as a key reagent, thus creating an extremely robust composite. All three immobilized catalysts described here were easily recovered and reused in numerous cycles. This work exemplifies the role of 3D printing in the design and manufacture of devices for compartmented multicatalytic systems to carry out complex one-pot transformations.
Circulation, Jan 11, 2018
BACKGROUND: Switching between different classes of P2Y 12 inhibitors, including de-escalation fro... more BACKGROUND: Switching between different classes of P2Y 12 inhibitors, including de-escalation from ticagrelor to clopidogrel, commonly occurs in clinical practice. However, the pharmacodynamic profiles of this strategy have been poorly explored. METHODS: This was a prospective, randomized, open-label study conducted in patients on maintenance dosing (MD) of aspirin (81 mg/d) and clopidogrel (75 mg/d). After a 7-day run-in with ticagrelor (180 mg loading dose [LD] followed by 90 mg twice daily MD), patients (n=80) were randomized into 1 of 4 groups: group A, clopidogrel 600 mg LD 24 hours after the last MD of ticagrelor (C-600 mg-24h); group B, clopidogrel 600 mg LD 12 hours after the last MD of ticagrelor (C-600 mg-12h); group C, clopidogrel 75 mg/d MD 24 hours after the last MD of ticagrelor (C-75 mg-24h); and group D, ticagrelor 90 mg twice daily MD (T-90 mg twice daily). MD of the randomized treatment was maintained for 10±3 days. Pharmacodynamic assessments were performed at baseline, after run-in, and at 2, 24, 48, and 72 hours and 10 days with P2Y 12 reaction units by VerifyNow; platelet reactivity index was assessed by vasodilator-stimulated phosphoprotein; and maximal platelet aggregation was determined by light transmittance aggregometry. RESULTS: T-90 mg twice daily led to lower platelet reactivity than any clopidogrel regimen using all assays at all time points. P2Y 12 reaction unit levels were similar between the C-600 mg-24h (group A) and the C-75 mg-24h (group C) (P=0.29), including at 48 hours (primary end point; least mean difference, −6.9; 95% confidence interval, −38.1 to 24.3; P=0.66). P2Y 12 reaction unit levels were lower with C-600 mg-12h (group B) than with C-75 mg-24h (group C; P=0.024). Maximal platelet aggregation over time was lower with both C-600 mg-24h (group A; P=0.041) and C-600 mg-12h (group B; P=0.028) compared with C-75 mg-24h (group C). Platelet reactivity index profiles paralleled those observed with P2Y 12 reaction units. There were no pharmacodynamic differences for all tests between C-600 mg-24h (group A) and C-600 mg-12h (group B). In group C (C-75 mg-24h), platelet reactivity increased compared with baseline as early as 24 hours, reaching statistical significance at 48 and 72 hours and up to 10 days. These pharmacodynamic findings were delayed and blunted in magnitude with the administration of an LD, regardless of the timing of administration. CONCLUSIONS: De-escalation from ticagrelor to clopidogrel therapy is associated with an increase in platelet reactivity. The use of an LD before the initiation of an MD regimen of clopidogrel mitigates these observations, although this is not affected by the timing of its administration after ticagrelor discontinuation.
Revista Mexicana de Ciencias Pecuarias, 2015
Las explotaciones de ovino de raza Manchega vinculadas a la enominación de origen protegido “Ques... more Las explotaciones de ovino de raza Manchega vinculadas a la enominación de origen protegido “Queso Manchego” son caracterizadas por aspectos técnicos, sociales y comerciales. A partir de una muestra aleatoria, estratificada y proporcional de 157 explotaciones, la información se obtuvo mediante encuesta directa al productor. La caracterización se realizó mediante análisis descriptivos. La muestra se estratificó en base al número de ovejas y uso de tecnología. Los grupos se compararon mediante un ANOVAC multifactorial. La explotación media responde a un sistema extensivo mixto agricultura-ganadería, de tipo pastoril (85 %), con 888 ovejas y 1,124 ha de superficie total (ST), el 18 % de la ST se usa en agricultura, el resto es pasto natural. El productor tiene 48 años en promedio, existe esperanza de continuidad en la actividad (91 %), y de relevo generacional (74 %). La comercialización se realiza en un 91 % por los canales comerciales tradicionales, y sólo en un 9 % por los canales...
PloS one, 2016
Circulating tumour cells (CTCs) play a key role in the metastasis process, as they are responsibl... more Circulating tumour cells (CTCs) play a key role in the metastasis process, as they are responsible for micrometastasis and are a valuable tool for monitoring patients in real-time. Moreover, efforts to develop new strategies for CTCs isolation and characterisation, and the translation of CTCs into clinical practice needs to overcome the limitation associated with the sole use of Epithelial Cell Adhesion Molecule (EpCAM) expression to purify this tumour cell subpopulation. CTCs are rare events in the blood of patients and are believed to represent the epithelial population from a primary tumour of epithelial origin, thus EpCAM immunoisolation is considered an appropriate strategy. The controversy stems from the impact that the more aggressive mesenchymal tumour phenotypes might have on the whole CTC population. In this work, we first characterised a panel of cell lines representative of tumour heterogeneity, confirming the existence of tumour cell subpopulations with restricted epith...
Analecta Malacitana, 2014
desde la crisis esteticista anterior a La via del rifugio (1907), hasta la elaboración y publicac... more desde la crisis esteticista anterior a La via del rifugio (1907), hasta la elaboración y publicación de I Colloqui (1911), y el sucesivo final de la actividad literaria de Gozzano. Se pone de manifiesto la tendencia de su poética hacia una poesía anticlasicista y antirromántica, aunque siempre a la sombra de la literatura clasicista y romántica italiana y europea contemporáneas.
Avances En El Metabolismo Del Nitrogeno De La Fisiologia a La Biologia Molecular Iv Reunion Nacional Marbella 1997 1998 Isbn 84 472 0402 2 Pags 355 360, 1998
Teoria Y Practica Para Una Ordenacion Racional Del Territorio 2010 Isbn 978 84 975668 8 9 Pags 301 320, 2010
El comercio electrónico, también conocido como e-commerce, consiste en la compra y venta de produ... more El comercio electrónico, también conocido como e-commerce, consiste en la compra y venta de productos o de servicios entre personas y empresas a través de medios electrónicos, principalmente Internet. El interés por el ecommerce en la actualidad es bastante elevado, las alternativas encontradas hasta ahora han permitido negociar desde el Ecuador hasta extremos insospechados, aunque siempre con la relativa inseguridad jurídica y económica que puede traer el negociar productos y servicios desde lugares físicos o con proveedores de servicios de Internet fuera de las fronteras nacionales. Con este antecedente, se propuso, mediante el uso de tecnología web, desarrollar un sitio que permita al público ecuatoriano gestionar los repuesto de vehículos en línea los 365 días del año, las 24 horas del día; brindando seguridad y agilitando el proceso del mismo. Para el desarrollo del mismo, se utilizó Joomla, un CMS o Gestor de Contenidos, que facilita que una persona sin conocimientos avanzados de lenguajes de programación pueda contar con herramientas para definir: creación y gestión de contenido, publicación y presentación de la información.
Academy of Management Proceedings, 2009
Drawing on the Upper Echelons perspective, we find that international experience and the average ... more Drawing on the Upper Echelons perspective, we find that international experience and the average tenure of the board are positively related and the average age of the directors is negatively related to internationalization. We find no relationship between the functional background and former government experience of the board and internationalization. Williamson OE. 1984. "The theory of trade in middle products: an extension". American Economic Review.Vol. 74 Issue 3, p485, 3p.
IEEE Communications Magazine, 2015
ABSTRACT The advent of spectrally flexible (a.k.a. elastic) optical networking is widely identifi... more ABSTRACT The advent of spectrally flexible (a.k.a. elastic) optical networking is widely identified as the next generation optical network solution that permits varying bandwidth demands to be dynamically assigned over flexible spectral containers, targeting optimum use of the available network resources. Additionally, the adoption of the space dimension is identified as a promising solution for the capacity expansion of future networks, while novel spatial-spectral switching solutions show that the flexible networking concept can be further expanded over both the spatial and spectral dimensions. This article provides an overview of the latest developments and possible approaches with respect to flexible optical networking and the emerging benefits that spatially flexible networking approaches can offer. The focus is on the network planning and resource optimization functions, the main network operations related to fragmentation and IP/optical layer integration, and the control plane solutions.
Italian Journal of Animal Science, 2015
Castilla La Mancha is a Spanish region where sheep farming system is traditionally pasture-based.... more Castilla La Mancha is a Spanish region where sheep farming system is traditionally pasture-based. Recently, this territory has undergone a recession of dairy sheep activity, which changed the type and intensity of land utilization and led to environmental and landscape degradation. The present study analyzed the diversity and viability of dairy sheep of mixed systems. Multivariate analysis was conducted on 157 dairy sheep farms, factor analysis selected 3 productivity factors (level of intensification, land use, size and family labour), and cluster analysis classified farms into three groups. Group 1, smallholders-with the smallest size (405.5 ewes and 564.7 ha), lowest area in ownership (1.5%), and agriculture activity (6.5% crops area): family farms (90.8%) highly dependent on external inputs. Group 2, large-scale farms (1058.7 ewes and 1755.1 ha)-with the lowest stocking rate (0.14 livestock unit/ha) and productivity: nonfamily farms (39.1%) with low area in ownership (4.1%) and agriculture activity (7.6%). Group 3, mixed-technified-with the highest levels of technology and least use of family labour (27.0%): large-scale farms (1387.4 ewes and 955.8 ha), combining milk production with agricultural activities (55.7% crops area), with the highest area in ownership (63.1%) and the best productivity performance. In conclusion, the dry land mixed system of Castilla La Mancha showed diversity of farms. Improving viability requires a systemic approach where the key tool is grazing, allowing the mixed system to be consolidated as a model that enhances the positive impact of livestock on the environment in the Mediterranean basin.
The international journal of cardiovascular imaging, 2014
The journal is listed 60/125 within the Cardiac & Cardiovascular Systems category and 40/121 with... more The journal is listed 60/125 within the Cardiac & Cardiovascular Systems category and 40/121 within the Radiology, Nuclear Medicine & Medical Imaging category. That means that we are in a respectable range and rank within the second quartile of both ISI categories. The 2013 IFcalculation was based on the following data:
Lecture Notes in Computer Science, 2013
User interaction experience has been lately the main focus of the industry of entertainment. High... more User interaction experience has been lately the main focus of the industry of entertainment. High rendered graphics and huge computing process have been lagging behind for paving the way to the user experience interaction in which the way the user gets involved with the system is a key point. For this reason, we present along with this paper an enhancement for video games and museum applications that is able to increase user experience by separating the display from the controller side, using mobile phones as tracking devices. For this purpose, we have implemented a system architecture based on a Bluetooth peer-to-peer model that establishes a strong connection between mobile phones and desktop applications. The utilization of mobile phones has been revealed as a fundamental element in user experience due to its ease of use and its widespread adoption among society, which makes possible to enter the competitive market of entertainment.
Uploads
Papers by Jose Carlos Rivas