Lichen Sclerosis is a chronic, progressive, atrophic, sclerosing process involving glans and prep... more Lichen Sclerosis is a chronic, progressive, atrophic, sclerosing process involving glans and prepuce. Cause of the disease is unknown. It occurs between 20 - 65 years of age. It manifests usually as atrophic patches, plaques. In severe cases waisting, effacement or muzzling are seen. It can lead tocomplications like meatal stenosis, urethral stricture and rarely carcinoma. Case one presented with lichen sclerosis complicated by squamous cell carcinoma and second case presented with urethral stricture. These two cases are being presented because of it’s rarity and these are likely to be missed. The patients were referred to surgery and urology depts respectively for further management.
International Journal of Health Sciences and Research, 2016
Background: Chronic idiopathic urticaria can pose a therapeutic challenge for the physician and c... more Background: Chronic idiopathic urticaria can pose a therapeutic challenge for the physician and can also be distressing for the patient. ASST helps in identification of auto immune urticaria and may stimulate the use of immunotherapy in severe disease that is unresponsive to conventional antihistamines. Aim: To determine the incidence of positive Autologous Serum Skin Test (ASST) in Chronic idiopathic urticaria and comparison of clinical and laboratory parameters of patients with positive and negative autologous serum skin test. Methods: In the present prospective observational study, 60 clinically diagnosed cases of chronic idiopathic urticaria attending the Department of Dermatology, Venereology, Leprology at Chalmeda Ananda Rao hospital were enrolled and ASST was done & results were compared with clinical & other lab parameters. Results: out of 60 enrolled patients ASST was positive in 21(35%) patients and ASST was negative in 39 (65%) patients. Conclusion: ASST was a simple and ...
International Journal of Environmental Monitoring and Analysis, 2017
This study was carried out for determination of Aerosol particulate matter (PM 10), trace gases (... more This study was carried out for determination of Aerosol particulate matter (PM 10), trace gases (SO 2 , NO 2 , CO) and heavy metals (Zn, Pb, Mn, Cu, Ni and Cd) in the atmospheric air of Karachi city. Sampling has been done at thirteen locations between during the year of 2014. The total average concentrations of SO 2 , NO 2 , CO and PM 10 were 65.9, 98.7, 1.49 and 202.14µg m-3 , respectively. An atomic absorption spectrophotometer (AAS) was used to determine the trace metal concentrations in the PM 10 size fraction. The total average concentrations of Cd, Zn, Pb, Mn, Cu and Ni in PM 10 were 0.09, 2.55, 2.23, 1.92, 2.15 and 1.44µg m-3 respectively. The Pb concentration in Karachi shows a decreasing tendency, presumably due to the ban on the use of leaded fuel. The overall trace metal concentrations in Karachi are higher than those in European (e.g., Spain, Norway) and East Asian (e.g., Taiwan) locations, but lower than those measured in Southeast Asian (Kanpur,
Lichen Sclerosis is a chronic, progressive, atrophic, sclerosing process involving glans and prep... more Lichen Sclerosis is a chronic, progressive, atrophic, sclerosing process involving glans and prepuce. Cause of the disease is unknown. It occurs between 20 - 65 years of age. It manifests usually as atrophic patches, plaques. In severe cases waisting, effacement or muzzling are seen. It can lead tocomplications like meatal stenosis, urethral stricture and rarely carcinoma. Case one presented with lichen sclerosis complicated by squamous cell carcinoma and second case presented with urethral stricture. These two cases are being presented because of it’s rarity and these are likely to be missed. The patients were referred to surgery and urology depts respectively for further management.
International Journal of Health Sciences and Research, 2016
Background: Chronic idiopathic urticaria can pose a therapeutic challenge for the physician and c... more Background: Chronic idiopathic urticaria can pose a therapeutic challenge for the physician and can also be distressing for the patient. ASST helps in identification of auto immune urticaria and may stimulate the use of immunotherapy in severe disease that is unresponsive to conventional antihistamines. Aim: To determine the incidence of positive Autologous Serum Skin Test (ASST) in Chronic idiopathic urticaria and comparison of clinical and laboratory parameters of patients with positive and negative autologous serum skin test. Methods: In the present prospective observational study, 60 clinically diagnosed cases of chronic idiopathic urticaria attending the Department of Dermatology, Venereology, Leprology at Chalmeda Ananda Rao hospital were enrolled and ASST was done & results were compared with clinical & other lab parameters. Results: out of 60 enrolled patients ASST was positive in 21(35%) patients and ASST was negative in 39 (65%) patients. Conclusion: ASST was a simple and ...
International Journal of Environmental Monitoring and Analysis, 2017
This study was carried out for determination of Aerosol particulate matter (PM 10), trace gases (... more This study was carried out for determination of Aerosol particulate matter (PM 10), trace gases (SO 2 , NO 2 , CO) and heavy metals (Zn, Pb, Mn, Cu, Ni and Cd) in the atmospheric air of Karachi city. Sampling has been done at thirteen locations between during the year of 2014. The total average concentrations of SO 2 , NO 2 , CO and PM 10 were 65.9, 98.7, 1.49 and 202.14µg m-3 , respectively. An atomic absorption spectrophotometer (AAS) was used to determine the trace metal concentrations in the PM 10 size fraction. The total average concentrations of Cd, Zn, Pb, Mn, Cu and Ni in PM 10 were 0.09, 2.55, 2.23, 1.92, 2.15 and 1.44µg m-3 respectively. The Pb concentration in Karachi shows a decreasing tendency, presumably due to the ban on the use of leaded fuel. The overall trace metal concentrations in Karachi are higher than those in European (e.g., Spain, Norway) and East Asian (e.g., Taiwan) locations, but lower than those measured in Southeast Asian (Kanpur,
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