Papers by Ravindra Gaikwad
Asian Journal of Pharmaceutical Research
Introduction: Psoriasis (Ps) is a well-known chronic non-infectious, inflammatory skin disease af... more Introduction: Psoriasis (Ps) is a well-known chronic non-infectious, inflammatory skin disease affecting about 2–3% of the worldwide Population. Pathogenesis includes the environmental trigger factors with other factors like genetic factors, trauma, chemicals, bacterial infection etc. Currently there is no drug which can permanently cure the skin lesions as well as completely eradicate this dermatosis. The purpose of this research is to investigate the anti-psoriatic activity of phytoconstituents of Tribulus terrestris by predicting the ligand-receptor binding and by predicting the ADMET parameters using Lipinski's rule. Methodology: The process of research work starts with protein and ligand structure preparation. Further docking was done using PyRxAutodock Vina. Afterward, analysis and visualisation of the interaction between protein-ligands was done, and ADMET profiling was carried out according to lipinski's rules using Swiss ADME. Result: we selected four phytoconstitue...
Bangladesh Journal of Pharmacology
Bangladesh Journal of Pharmacology
Novel Approaches Towards Wastewater Treatment and Resource Recovery Technologies
Sustainable Water Treatment
Agricultural development is unique sign for development of agricultural base country. Multi-crite... more Agricultural development is unique sign for development of agricultural base country. Multi-criteria, AHP and influence based analysis is suitable for agricultural development. Six criterions (Crops) sugarcane, vegetables, pulses, fruits, rice and grains were selected for development indicators of Upper Mula basin in Ahmednagar district, Maharashtra (India). Expert opinions for ranking the criterion selected for influence. Sugarcane, vegetables and fruits show higher influences on development of watershed arrangement in the study area. Further, crops grains and pluses were show significant influence in kharip season. Using AHP techniques for influences were calculated based on weights estimated. Normalized and distribution of specific crops using the values of influences within the sub-watersheds. Agriculture developments influence are classified into very low (< Mean-1STD), low (Mean-1STD to Mean), moderate (Mean to Mean + 1STD), high (Mean + 1STD to Mean + 2STD), and very high ...
2017 International Conference on Trends in Electronics and Informatics (ICEI), 2017
This paper represents the development of flexible sensor which works under the principle of paral... more This paper represents the development of flexible sensor which works under the principle of parallel plate capacitor. Conventional screen printing technique is used for the fabrication of printed pressure sensor. The sensor was printed on PET substrate. Ag and dielectric materials were used to analyze the performance of sensor. Thermal and UV curing was performed with respect to the material property. Samples were printed with respect to different layer thickness to achieve better sensitivity. By using same principle, various sensor design was implemented for musical and bio-medical applications. Electrical and mechanical characterization showed the sensor output of 0.2 F under compressive force of <5 N/cm2.
The general purpose of the experimental investigations described here has to study the hydrodynam... more The general purpose of the experimental investigations described here has to study the hydrodynamic properties of gas-liquid fluidized beds. Gas –liquid fluidization of or three-phase fluidization is a chemical engineering operation where all the three phases are brought into contact with each other. This contact is brought about by passing the gas and liquid trough the bed of solids. The solids are said to be in a fluidized state when they are suspended in the continuous phase.Hydrodynamic properties such as gas hold-up, liquid hold-up and bed porosity have been studied. These properties depend upon certain independent variables such as gas flow rates, liquid flow rate, particle size, static bed heights, gas density, liquid density, solid density, liquid surface tension, liquid viscosity, gas viscosity and particle shape. During the course of this experimental investigation only four of these parameters have been varied, viz, gas flow rates, liquid flow rates, static bed height and...
Chemical engineering students and chemical engineers are being asked to solve problems that are c... more Chemical engineering students and chemical engineers are being asked to solve problems that are complex, whether the applications are in refineries, chemical or pharmaceutical plants. The aim of this book is to demonstrate the problems in chemical engineering which have to solve by Finite Difference Methods. This book is a thorough presentation of Finite Difference Methods used in Chemical Engineering. The goal of this book is to help you practice better chemical engineering. It also contains case studies with worked out examples to demonstrate the Finite Difference Method. This book is for the Chemical Engineer lays down a foundation for numerical problem solving and sets up a basis for more in-depth theory and applications. This text addresses the needs of senior undergraduates in chemical engineering, and students in applied chemistry and biochemical process engineering/food process engineering also.
Anaerobic treatment of municipal solid waste leachate is the treatment process of leachate genera... more Anaerobic treatment of municipal solid waste leachate is the treatment process of leachate generated in solid waste disposal site. Biological treatment removes the most contaminants, by converting it into less harmful substances. This process is natural process which use the naturally available organisms in the environment. In this paper the process of anaerobic treatment of municipal solid waste leachate and recovering the methane gas produced is presented. The UASB bioreactor was operated at 3 different processes i.e. batch process, semi-continuous process and continuous process. The results of these three processes are compared and semi-continuous process gives the best results. The results of semi-continuous process at 3 day HRT are 96.6% COD reduction, TVA reduced from 954 mg/L, alkalinity increased from 160 mg/L to 1180 mg/L. Total solids reduction was 68.14%, suspended solids reduction was 86%, volatile solids reduction was 86.7% and biogas production was 2650 ml.
Scientific Reports, 2021
The levels of hydrogen peroxide ($${\mathrm{H}}_{2}{\mathrm{O}}_{2}$$ H 2 O 2 ) in human blood is... more The levels of hydrogen peroxide ($${\mathrm{H}}_{2}{\mathrm{O}}_{2}$$ H 2 O 2 ) in human blood is of great relevance as it has emerged as an important signalling molecule in a variety of disease states. Fast and reliable measurement of $${\mathrm{H}}_{2}{\mathrm{O}}_{2}$$ H 2 O 2 levels in the blood, however, continues to remain a challenge. Herein we report an automated method employing a microfluidic device for direct and rapid measurement of $${\mathrm{H}}_{2}{\mathrm{O}}_{2}$$ H 2 O 2 in human blood based on laser-induced fluorescence measurement. Our study delineates the critical factors that affect measurement accuracy—we found blood cells and soluble proteins significantly alter the native $${\mathrm{H}}_{2}{\mathrm{O}}_{2}$$ H 2 O 2 levels in the time interval between sample withdrawal and detection. We show that separation of blood cells and subsequent dilution of the plasma with a buffer at a ratio of 1:6 inhibits the above effect, leading to reliable measurements. We demo...
The Analyst, 2021
We present novel technology for the optofluidic detection and electro-coalescence-based sorting (... more We present novel technology for the optofluidic detection and electro-coalescence-based sorting (selective isolation) of target cells in single-cell format from background cells, utilizing microdroplet encapsulation.
Hydrospatial Analysis, 2018
Watershed is unique bio-physical unit of the Earth surface and source of resources to the human, ... more Watershed is unique bio-physical unit of the Earth surface and source of resources to the human, animal and plants. AHP based multi-criteria analysis is suitable for prioritization of sub-watersheds in medium river basin for planning, management and development. Twenty five criterion i.e. area, morphimery, geology, slope, soil, rainfall and population density were selected for prioritization of medium watersheds of Upper Mula basin in Maharashtra (India). Correlation analysis is suitable for ranking the criterion selected for prioritization. Texture Ratio (25.94%), drainage texture (12.97%), stream order (8.65%), total stream length (6.49%) and ruggedness number (5.19%) show higher influences on development of watershed structure in the study area. Further, criterion like geology, rainfall, soil and population were show considerable influence in prioritization of sub-watersheds in medium river basin. Influences were estimated based on weights calculated using AHP technique. Values ...
Hydrospatial Analysis, 2018
Watershed is unique bio-physical unit of the Earth’s surface and source of resources to the peopl... more Watershed is unique bio-physical unit of the Earth’s surface and source of resources to the people. These resources are being exploited for various purposes. AHP based multi-criteria analysis is useful for prioritization of watersheds for planning, management and development. Nineteen criterion i.e. Rb, Lb, A, Lb, P, Dd, P, Fs, Rf, Re, CC, Dt, T, Di, If, Rh1, Rn , slope and soils were selected for prioritization of sub-watersheds of Kas basin in Maharashtra (India). Correlation analysis suitable for robust judgment for ranking the criterion was used for prioritization of selected watersheds. Drainage intensity (27.80%), texture ratio (13.90%), bifurcation ratio (9.27%), geology (6.95%) and basin length (5.56%) show higher influence on formation of watershed structure in the region. Influences of criterion were estimated based on weights calculated using AHP techniques. Values of influences were normalized using distribution of selected criterion within the sub-watersheds. Watersheds...
Liquid-Liquid Extraction is one of the most significant unit operations used widely in the chemic... more Liquid-Liquid Extraction is one of the most significant unit operations used widely in the chemical industry for the separation of liquid-liquid mixture with the aid of an extracting solvent. There are different contacting patterns for the said purpose viz. co-current, counter current and crosscurrent and also a variety of equipments are encountered. This paper deals with the simulation of counter current liquid-liquid extraction operation for the special case of immiscible solvent using MATLAB. In this paper seven case studies have been studied and the results obtained are compared with the literature and it was found that results are in good agreement with the literature available.
The removal of nickel from acid mine drainage waste by ion exchange resins, such as Indion 820 an... more The removal of nickel from acid mine drainage waste by ion exchange resins, such as Indion 820 and Indion 850, was investigated. Effect of initial metal ion concentration, resin dose and pH on exchange capacities of ion exchange resins was studied in a batch method. The adsorption process, which is pH dependent, shows maximum removal of nickel in the pH range 2-6 for an initial nickel concentration of 50-250 mg/L and with resin dose 25-700 mg/L. The experimental data have been analyzed by using the Freundlich, Langmuir, Redlich-Peterson, Temkin and Dubinin-Radushkevich isotherm models. The isotherm constants for all these isotherm models have been calculated. The uptake of nickel by the ion exchange resins was reversible and thus has good potential for the removal/recovery of nickel from acid mine drainage wastewater. Ion exchange resins, such as Indion 820 and Indion 850 can be used for the efficient removal of nickel from mine wastewater.
Journal of Water Resource and Protection, 2010
A factorial experimental design method was used to examine the "Cu 2+ " removal from acid mine dr... more A factorial experimental design method was used to examine the "Cu 2+ " removal from acid mine drainage wastewater by ion exchange technique. Ion Exchange technique is preferred because of reduced sludge generation compared to conventional treatment techniques and better decontamination efficiency from highly diluted solutions. Factorial design of experiments is employed to study the effect of four factors pH (3, 5, and 6), flow rate (5, 10, 15 L/hr), resin bed height (20, 40 and 60 cm) and initial concentration of the metal (100, 150 and 200 mgl-1) at three levels. The efficiency of metal removal was determined after 100 min of treatment. Main effects and interaction effects of the four factors were analyzed using statistical techniques. A regression model was recommended and it was found to fit the experimental data very well. The results were analyzed statistically using the Student's t-test, analysis of variance, F-test and lack of fit to define most important process variables affecting the percentage "Cu 2+ " removal. In this study, pH was thus found to be the most important variable.
International Journal of Chemical Engineering and Applications, 2011
Sugar cane bagasse ash, an agricultural byproduct, acts as an effective adsorbent for the removal... more Sugar cane bagasse ash, an agricultural byproduct, acts as an effective adsorbent for the removal of dyes from aqueous solution. Batch adsorption study was investigated for the removal of Acid Orange-II from aqueous solution. Adsorbents are very efficient in decolorized diluted solution. The effects of bed depth on breakthrough curve, effects of flow rate on breakthrough curve were investigated. The removal of dyes at different flow rate (contact time), bed height, initial dye concentration, column diameter, pH & temperature by Sugarcane Bagasse Ash as an adsorbent has been studied. It is found that percent adsorption of dyes increases by decreasing flow rate from 2 lit/hr to 1 lit/hr, by increasing bed height from 15cm to 45cm, by decreasing initial conc.150mg/lit to 100mg/lit, by increasing column diameter from 2.54cm to 3.5cm,by maintaining neutral pH & at temperature 45ºc than 25ºc & 35ºc.The result shows that, bagasse ash is a good adsorbent for dye effluent treatment.
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Papers by Ravindra Gaikwad