The Journal of Middle East and North Africa Sciences, 2018
Beta-carotene (βC), an antioxidant found in fruits and vegetables is responsible for the yellow c... more Beta-carotene (βC), an antioxidant found in fruits and vegetables is responsible for the yellow color of these plants. The aim of the present research was to investigate the morphometric changes on Wistar rats fed high dietary fat and βC. Thirty (30) male Wistar rats were randomly grouped into 6. Group A was the Control and received distilled water, Group B received high-fat diet of 60% fat and 40% rat chow, Group C received 300mg/kg body weight (BW) of βC, Group D received high-fat diet for 12 weeks and was treated with 300mg/kg BW of βC for 2 weeks, Groups E received 300mg/kg BW of βC for 2 weeks and then received high-fat diet for12 weeks while Group F received high-fat diet for 12 weeks and was treated with 150mg/kg BW of βC for 2 weeks. At the end of 16 weeks, the weights, head-tail lengths were measured and the animals humanely sacrificed, the weights of the liver measured. The results showed that increase in high-fat diets did not sequel increase in the body weight and liver weight in the treated groups. When compared to Groups D and F, Group C showed increased body and liver weights but these were lower than that observed in Group A. The liver weight was increased in animals feed dietary fat alone when compared to Group A. The result showed that Lee index was higher in Groups D and F when compared to Groups B and E. The results of the present study suggest that β carotene extract can be very effective in treating weight gain due to high fat diets.
Journal of Advances in Medicine and Medical Research
Background: Beta-carotene (βC), an antioxidant present in fruits and vegetables responsible for t... more Background: Beta-carotene (βC), an antioxidant present in fruits and vegetables responsible for the yellow coloration of these plants has been used for ages as remedies against different ailments. The present study was aimed at investigating tumor necrosis factor (TNF-α) and plasma glucose level changes due to dietary fat and β-carotene in Wistar rats. Methods: Thirty (30) male Wistar rats were grouped into 6. Group A was the Control and received distilled water, Group B received high fat diet of 60% fat and 40% rat chow, Group C received 300 mg/kg body weight (bwt) of βC, Group D received high-fat diet for 12 weeks and was treated with 300 mg/kg bwt of βC for 2 weeks, Group E received 300mg/kg bwt of βC for 2 weeks and then highfat diet for 12 weeks while Group F received high-fat diet for 12 weeks and then treated with 150
The Journal of Middle East and North Africa Sciences, 2018
Beta-carotene (βC), an antioxidant found in fruits and vegetables is responsible for the yellow c... more Beta-carotene (βC), an antioxidant found in fruits and vegetables is responsible for the yellow color of these plants. The aim of the present research was to investigate the morphometric changes on Wistar rats fed high dietary fat and βC. Thirty (30) male Wistar rats were randomly grouped into 6. Group A was the Control and received distilled water, Group B received high-fat diet of 60% fat and 40% rat chow, Group C received 300mg/kg body weight (BW) of βC, Group D received high-fat diet for 12 weeks and was treated with 300mg/kg BW of βC for 2 weeks, Groups E received 300mg/kg BW of βC for 2 weeks and then received high-fat diet for12 weeks while Group F received high-fat diet for 12 weeks and was treated with 150mg/kg BW of βC for 2 weeks. At the end of 16 weeks, the weights, head-tail lengths were measured and the animals humanely sacrificed, the weights of the liver measured. The results showed that increase in high-fat diets did not sequel increase in the body weight and liver weight in the treated groups. When compared to Groups D and F, Group C showed increased body and liver weights but these were lower than that observed in Group A. The liver weight was increased in animals feed dietary fat alone when compared to Group A. The result showed that Lee index was higher in Groups D and F when compared to Groups B and E. The results of the present study suggest that β carotene extract can be very effective in treating weight gain due to high fat diets.
Journal of Advances in Medicine and Medical Research
Background: Beta-carotene (βC), an antioxidant present in fruits and vegetables responsible for t... more Background: Beta-carotene (βC), an antioxidant present in fruits and vegetables responsible for the yellow coloration of these plants has been used for ages as remedies against different ailments. The present study was aimed at investigating tumor necrosis factor (TNF-α) and plasma glucose level changes due to dietary fat and β-carotene in Wistar rats. Methods: Thirty (30) male Wistar rats were grouped into 6. Group A was the Control and received distilled water, Group B received high fat diet of 60% fat and 40% rat chow, Group C received 300 mg/kg body weight (bwt) of βC, Group D received high-fat diet for 12 weeks and was treated with 300 mg/kg bwt of βC for 2 weeks, Group E received 300mg/kg bwt of βC for 2 weeks and then highfat diet for 12 weeks while Group F received high-fat diet for 12 weeks and then treated with 150
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