Papers by Nur Hafidha Hikmayani
Background. Numbers of new cases of type 2 diabetes (T2D) are increasing rapidly. Early and conti... more Background. Numbers of new cases of type 2 diabetes (T2D) are increasing rapidly. Early and continuing intervention after T2D presentation is crucial for best possible outcomes, ensuring that the existing high burden of T2D will not be aggravated. Identification of patterns of continuous care and predictors for meeting key targets for T2D management can improve quality of care. Glycaemic control is particularly important for primary prevention of vascular complications but its relationship with contemporary cardiovascular diseases (CVDs) has been less explored. More importantly, long-term glycaemic control can be assessed from routine monitoring, potentially providing new insight into T2D management to prevent vascular complications. Linked electronic health records are invaluable data resources for investigating these issues. Objective. To examine the quality of care in an incident T2D cohort through assessment of temporal trends of care, predictors of glycaemic, blood pressure and...
Value in Health, 2012
OBJECTIVES: Bipolar disorder (BD) is associated with a high burden on healthcare resources. A sec... more OBJECTIVES: Bipolar disorder (BD) is associated with a high burden on healthcare resources. A secondary objective of the Wide AmbispectiVE study of the clinical management and burden of bipolar disorder (WAVE-bd) was to assess healthcare resource utilization among BD patients. METHODS: Multinational, multicenter, non-interventional, cohort study of patients diagnosed with BD-I/BD-II with Ն1 mood episode in the preceding 12 months (retrospective data collection) followed by a minimum 9 months' prospective follow-up. Study population was representative of BD populations from 8 European and 2 Latin American countries. Multivariate analyses determined factors associated with higher incidence of resource use (number of visits per year), measured by parameter estimates (ParEst [95% CI]) Ͼ0. RESULTS: Multivariate analyses included 2,896 patients. Factors associated with a higher incidence of hospitalizations included: psychotic symptoms during the study index episode (0.08 [0.02; 0.14]); a higher number of previous hospitalizations (0.04 [0.03; 0.04]); receiving anxiolytics during the study index episode (0.12 [0.06; 0.17]); enrolment in hospital settings (0.13 [0.03; 0.23]). The incidence of emergency room visits was increased in patients with: rapid cycling (0.13 [0.06; 0.19]); a history of suicide attempts (0.08 [0.02; 0.14]); a higher number of previous hospitalizations (0.01 [0.01; 0.02]). The incidence of programmed psychiatrist visits was increased in patients: with rapid cycling (0.90 [0.36; 1.44]); with a higher number of previous hospitalizations (0.11 [0.06; 0.16]); enrolled in private practices (1.31 [0.07; 2.55]); receiving antipsychotics during study index event (0.81 [0.37; 1.25]). Overall, clinical factors associated with higher incidence of resource use included: rapid cycling (2.22 [0.84; 3.61]); co-morbidity of thyroid disease (2.21 [0.49; 3.92]); a higher number of previous hospitalizations (0.25 [0.12; 0.38]); receiving antipsychotics during the study index episode (1.63 [0.50; 2.76]). CONCLUSIONS: Several clinical factors are associated with higher resource utilization in BD patients. These factors could aid in identification of high-risk patients.
Value in Health, 2010
duration of known diabetes was 6.80 ± 6.67 years. A substantial negative impact of diabetes on th... more duration of known diabetes was 6.80 ± 6.67 years. A substantial negative impact of diabetes on the participants' HRQoL was observed as assessed by the ADDQoL (mean ± SD average weighted impact (AWI) score: −3.76 ± 2.03 from the possible range −9 to +3), although the level of their TS was rather high as assessed by the DTSQs (mean ± SD TS scale total: 28.60 ± 5.53 out of 36). The participants' EQ-5D scores (mean ± SD EQ-utility score: 0.74 ± 0.20; EQ-VAS score: 65.22 ± 17.54) were only slightly lower than the norm values for the general population (0.80 ± 0.26 and 79.74 ± 18.23 for the two scores, respectively). Higher income was signifi cantly associated with better health status while lower education and unemployment status were signifi cantly associated with poorer HRQoL. Female gender and older age were associated with higher TS. CONCLUSIONS: Diabetes had major impact on the participants' HRQoL but little impact on health status despite a high level of TS. Patient characteristics associated with these outcomes were also different.
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Papers by Nur Hafidha Hikmayani