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Asma Nigar

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Papers by Asma Nigar

Morphological, Morphometric, and Histological Evaluation of the Placenta in Cases of Intrauterine Fetal Death

Curēus, Jun 21, 2024

Background The human placenta is a remarkable organ that develops during pregnancy and is crucial... more Background The human placenta is a remarkable organ that develops during pregnancy and is crucial in supporting fetal growth and development. The placenta supplies oxygen and nutrients to the fetus and removes waste products from the fetal bloodstream. It also produces hormones that support pregnancy, such as human chorionic gonadotropin, progesterone, and estrogen. Placental insufficiency occurs when the placenta cannot deliver adequate nutrients and oxygen to the fetus. This can result in intrauterine fetal death (IUFD), stillbirth, intrauterine growth restriction, low birth weight, and premature birth. It can also be associated with developmental delays or long-term health issues for the baby. This study aimed to assess the morphologic, morphometric, and histologic changes in the placenta associated with IUFD and compare it with the placenta of live births.

A study on awareness, knowledge and attitude towards cervical cancer and its prevention among women having cervical abnormalities in Lucknow, India

International Journal of Chemical and Biochemical Sciences, 2024

Étude de l’utilisation de l’inhalateur connecté Connect’inh en vie réelle et de sa pertinence pour répondre aux besoins des patients asthmatiques et atteints de bronchopneumopathie chronique obstructive

Revue D Epidemiologie Et De Sante Publique, Jun 1, 2019

Objectifs Connect’inh est un dispositif connecte developpe par la start-up Kap Code et destine au... more Objectifs Connect’inh est un dispositif connecte developpe par la start-up Kap Code et destine aux patients atteints de pathologies respiratoires chroniques comme l’asthme ou la bronchopneumopathie chronique obstructive (BPCO). Cette etude a ete realisee en condition reelle d’utilisation afin de s’assurer de la pertinence de l’objet pour repondre aux besoins des patients mais aussi pour evaluer au cours du temps le degre d’appropriation de l’objet par les utilisateurs finaux de Connect’inh. Methode L’etude a ete menee avec des patients atteints de pathologies respiratoires (asthme et BPCO) recrutes via les reseaux sociaux (Twitter, Facebook, LinkedIn, Google). Les patients ont ete suivis pendant trois mois. Au total, 42 personnes (18 hommes et 24 femmes) ont participe a l’etude : 14 % avaient entre 18 et 25 ans, 43 % entre 25 et 34 ans, 26 % entre 35 et 49 ans et 17 % plus de 50 ans. Trois questionnaires ont ete administres en ligne : le premier questionnaire avait pour but d’explorer le profil des malades et leurs attentes concernant un objet connecte, avant la prise en main de l’objet Connect’inh. Un deuxieme questionnaire a ete administre une semaine apres la prise en main de l’objet puis, un troisieme apres trois mois d’utilisation. Une analyse statistique a ensuite permis de classifier et mettre en regard les attentes des patients et la reponse aux besoins en vie reelle grâce a l’objet Connect’inh. Resultats L’analyse des questionnaires prealables a pu montrer que 63 % des patients estimaient que le suivi de leur pathologie chronique respiratoire n’etait pas suffisant, et qu’ils souhaitaient un outil adaptable permettant un suivi personnalise (suivi des crises, information sur les traitements de fond ou de crise) couple a des informations sur l’environnement (notification sur la qualite de l’air) ; 100 % des patients ont estime qu’un inhalateur connecte comme Connect’inh pouvait repondre a leurs besoins. Les patients n’ont pas ete reticent a l’utilisation d’un objet connecte ou a l’utilisation de la geolocalisation via l’application, et ce, quel que soit l’âge des participants aux questionnaires. Au final, apres une semaine d’utilisation, 63 % des patients beta-testeurs estimaient que Connect’inh repondait a leurs besoins, et 78 % recommanderaient le produit a une autre personne souffrant d’une pathologie respiratoire chronique. Conclusion Cette etude a permis de s’assurer de la bonne appropriation d’un objet connecte et sa pertinence en condition reelle d’utilisation par des patients atteints de pathologies respiratoires. L’analyse des donnees met en evidence que les patients asthmatiques et/ou atteints de BPCO sont aujourd’hui en majorite demandeurs de davantage de suivi pour leur pathologie respiratoire, et qu’un objet connecte pourrait etre un moyen d’y parvenir. Dans les conditions reelles d’utilisation, les patients ont estime que Connect’inh pouvait repondre a leurs besoins. Un suivi a plus long terme sera necessaire pour s’assurer de l’appropriation de l’inhalateur connecte dans la duree et s’interesser a l’impact d’un tel dispositif sur la frequence et la gravite des crises.

Contraceptive awareness, and practices among rural women in Lucknow

Indian Journal of Obstetrics and Gynecology Research, Dec 15, 2020

Objective: This cross sectional observational study was done to asses awareness regarding family ... more Objective: This cross sectional observational study was done to asses awareness regarding family planning methods and the practice of contraceptives among rural women in Lucknow. Materials and Methods: Five hundred women between the ages of 15-45 years, living with their husbands and coming from rural area, attending gynecology OPD of integral institute of medical sciences and research, Dasauli, Lucknow were included in this study. Women who were pregnant, had a child younger than 2 years, or had any medical disorder were excluded. Their knowledge, source of knowledge and practice of contraceptives were evaluated with the help of a predesigned questionnaire. The other variables used were the age of women, parity, religion and educational status. Results were expressed as percentages. Results: Out of 500 interviewed majority of women (49.2%) were between 22-25 years of age. 61% were illiterate belonging to low socioeconomic status, 63.3% belonged to Hindu religion. In the present study, it was observed that, 94.4% had some knowledge about family planning methods, and almost all (94.4%) of them were aware about Cu T and oral pills. The media and social circle were provided information of contraceptives in 46.6% women. Regarding the usage of contraceptive methods, 41.2% of the respondents were using some sort of contraception. Barrier method (condoms) was in practice by 26.8%, pills in 5.6%. Cu T users were 3.2% and 1.2% were using DMPA for contraception. 4.4% of women had already undergone tubal ligation. It was noted that awareness about pills and Copper was good, but their practices were very low. There were multiple reasons for non use like fear of side effects, no support from the husbands, low fertility, inhibition to ask about the contraceptives. Conclusion: There is need for strong motivation of couples through media and health personnel to achieve effective use of contraceptives, specially for Cu T and oral pills.

Awareness of cervical cancer risk factors and screening methods among women attending a tertiary hospital in Lucknow, India

International journal of reproduction, contraception, obstetrics and gynecology, Nov 23, 2017

Cancer cervix is the second most common cancer among women after breast cancer worldwide. Accordi... more Cancer cervix is the second most common cancer among women after breast cancer worldwide. According to WHO, cancer cervix comprises 12% of all cancers in women and is the leading gynaecological malignancy in the world. In contrast to developed countries, cancer cervix is a major public health problem in developing countries like India. India alone accounts for one-quarter of the worldwide burden of cervical cancers. 1,2 It is one of the leading cause of cancer related deaths, accounting for 17% of all cancer deaths among women aged between 30 and 69 years. It is estimated that cancer cervix will occur in approximately 1 in 53 Indian women during their lifetime compared with 1 in 100 women in more developed regions of the world.

Seroprevalence of Hepatitis B virus surface antigen among pregnant females attending antenatal clinic at a tertiary care hospital in North India

International Journal of Research in Medical Sciences, Dec 25, 2019

Background: Hepatitis B infection is one of the most common public health problems worldwide. Hep... more Background: Hepatitis B infection is one of the most common public health problems worldwide. Hepatitis B virus Surface Antigen (HBsAg) positive mothers may transmit the virus vertically to neonates transplacentally during pregnancy, perinatally during delivery or postnatally through breast milk. Such neonates being carriers of virus are at a very high risk of developing chronic liver diseases at a younger age and also, they act as reservoirs of infection in the community. Objective of the study is to evaluate the seroprevalence of HBsAg in pregnant females attending Antenatal Clinic. Methods: A hospital based cross-sectional study was done from January to June 2019. A total of 840 pregnant females were included in the study who attended Antenatal Clinic for routine checkup whose blood samples were sent to Microbiology Laboratory for screening of HBsAg by Enzyme Linked Immunosorbent Assay (ELISA). Results: Out of 840 pregnant females included in the study, 8 were reactive to HBsAg, hence, prevalence was found to be 0.95%. The seroprevalence of HBsAg was found to be more (1.40%) in 26-35 year females. Maximum seropositivity was seen in females from urban areas (1.0%), those attending OPD of ANC (1.03%) and those who belonged to lower socioeconomic class (1.02%). Conclusions: Routine free screening for HBV infection should be offered to all antenatal females to reduce the risk of vertical transmission to the neonates born to infected mothers, thereby, preventing them from becoming carriers and developing chronic hepatitis and hepatocellular carcinoma later in life.

Role of 17 α Hydroxy Progesterone Caproate (17OHPC) in the Prevention of Preterm Labor

The Journal of Obstetrics and Gynecology of India, Aug 1, 2012

Objective To evaluate the role of 17 a hydroxyprogesterone caproate (17OHPC) in the prevention of... more Objective To evaluate the role of 17 a hydroxyprogesterone caproate (17OHPC) in the prevention of preterm labor in high risk asymptomatic patients with a history of preterm delivery. Methods The study included 96 patients with a singleton pregnancy and having a prior preterm birth. They were divided in 2 groups, group I (treatment group) included 46 asymptomatic patients who were given 17OHPC injections starting from 16-20 weeks till 36 weeks and group II (control group) included 50 patients who did not receive any treatment. Results The incidence of preterm delivery was found to be 6.9 %. The median gestational age at delivery was 36 weeks in group I and 33 W5D in controls. 50 % cases in group I and 80 % of controls delivered prematurely in the group with a prior preterm birth between 20-28 weeks. Conclusion In patients who had a prior history of a preterm delivery the recurrence of a preterm birth was less in the treated group as compared to controls. The median gestational age at delivery was significantly higher in 17OHPC treated patients with history of earliest prior preterm delivery at 20-28 weeks.

A Rare Cause of Postpartum Back Ache: Osteitis Condensans Ilii

The Journal of Obstetrics and Gynecology of India

Prevalence of Hepatitis B Infection among Female Patients Attending Integral IMS & Research Hospital, Lucknow

Hepatitis B infection is caused by hepatitis B virus (HBV), an enveloped DNA virus belonging to f... more Hepatitis B infection is caused by hepatitis B virus (HBV), an enveloped DNA virus belonging to family Hepadnaviridae that infects the liver and causes hepatocellular necrosis and inflammation which are serious public health problem worldwide. The Present study was conducted in the department of microbiology on 456 female patients. The serums were obtained by centrifugation & test was done. The Hepatitis B surface Ag was detected by using HEPACARDS kit. In our current study on 456 female patients were screened for HBsAg and we found that 5.3% female patients were reactive with HBsAg in serum and 94.7% were Non reactive with HBsAg out of 456 female patients. Higher prevalence of HBsAg was reported in most sexually active age group.i.e.21-40 years (57.5%) and least in age group 81-100 (0.4%). In the light of current study, it can be concluded that the Hepatitis B contributes significantly to chronic liver diseases in India and being transmitted through parenteral, sexual or perinatal ...

To Evaluate the Effect of 17 Alpha Hydroxyprogesterone Caproate (17OHPC) As a Maintenance Tocolytic in Preterm Labor

Aims & ObjectiveTo evaluate the efficacy of of 17 alpha hyroxyprogesterone caproate after acute t... more Aims & ObjectiveTo evaluate the efficacy of of 17 alpha hyroxyprogesterone caproate after acute tocolysis with nifedipine in preventing preterm delivery. Material & MethodsIt was a prospective clinical trial that was carried out on 100 pregnant females between 2834 weeks of gestation diagnosed with preterm labor pains All patients in pretrm labor were given nifedipine for acute tocolysis and antenatal corticosteroid was given to all patient for lung maturity. After tocolysis undelivered patients were randomly allocated to progesterone(n=50) and control group(n=50).Patients in Progesterone were given 17 alpha hyroxyprogesterone caproate, 250 mg, weekly and continued till 36 weeks of gestation or delivery, which ever occurred earlier. Control group were given nifedipine as a maintanencetocolysis as and when required. Results were analysed in terms of gestational age at delivery and neonatal outcome in both groups. Results-Mean gestational age at delivery was 35.2±2.3 weeks in progeste...

Contraceptive awareness, and practices among rural women in Lucknow

Indian Journal of Obstetrics and Gynecology Research

Objective: This cross sectional observational study was done to asses awareness regarding family ... more Objective: This cross sectional observational study was done to asses awareness regarding family planning methods and the practice of contraceptives among rural women in Lucknow. Materials and Methods: Five hundred women between the ages of 15-45 years, living with their husbands and coming from rural area, attending gynecology OPD of integral institute of medical sciences and research, Dasauli, Lucknow were included in this study. Women who were pregnant, had a child younger than 2 years, or had any medical disorder were excluded. Their knowledge, source of knowledge and practice of contraceptives were evaluated with the help of a predesigned questionnaire. The other variables used were the age of women, parity, religion and educational status. Results were expressed as percentages. Results: Out of 500 interviewed majority of women (49.2%) were between 22-25 years of age. 61% were illiterate belonging to low socioeconomic status, 63.3% belonged to Hindu religion. In the present study, it was observed that, 94.4% had some knowledge about family planning methods, and almost all (94.4%) of them were aware about Cu T and oral pills. The media and social circle were provided information of contraceptives in 46.6% women. Regarding the usage of contraceptive methods, 41.2% of the respondents were using some sort of contraception. Barrier method (condoms) was in practice by 26.8%, pills in 5.6%. Cu T users were 3.2% and 1.2% were using DMPA for contraception. 4.4% of women had already undergone tubal ligation. It was noted that awareness about pills and Copper was good, but their practices were very low. There were multiple reasons for non use like fear of side effects, no support from the husbands, low fertility, inhibition to ask about the contraceptives. Conclusion: There is need for strong motivation of couples through media and health personnel to achieve effective use of contraceptives, specially for Cu T and oral pills.

Awareness of cervical cancer risk factors and screening methods among women attending a tertiary hospital in Lucknow, India

International Journal of Reproduction, Contraception, Obstetrics and Gynecology

Background: Cervical cancer is the second most common cancers among women worldwide after breast ... more Background: Cervical cancer is the second most common cancers among women worldwide after breast cancer. It is the only cancer in which early diagnosis of precancerous lesions can be done by a very simple and sensitive test that is, paps test. Knowledge of the women about cervical cancer risk factors and awareness about its screening are the key factors that may decrease the mortality and morbidity caused by cancer cervix. Most of the cases of cervical cancer in India are diagnosed very late, because of lack of awareness about risk factors and screening methods, resulting in fatal outcome. So, this study was done to assess the knowledge of risk factors for cervical cancer, and paps smear test for its screening.Methods: This cross-sectional study was conducted among 200 women aged 18-55 years, attending Gynaecology Out-Patient Department (OPD) in a tertiary care hospital in Lucknow. Information about their knowledge of cervical cancer, awareness of its prevention and their socio demo...

Prevalence of anemia in pregnancy at booking: a retrospective study at a tertiary care centre in Lucknow India

International Journal of Reproduction, Contraception, Obstetrics and Gynecology

Background: Anemia in pregnancy is one of the most common nutritional deficiency disorders affect... more Background: Anemia in pregnancy is one of the most common nutritional deficiency disorders affecting the pregnant women in the developing countries. The aim of our study was to understand the prevalence of anemia among pregnant women, and factors associated with anemia.Methods: It was a retrospective record based study conducted in pregnant women, attending antenatal clinic and emergency in the Department of Obstetrics and Gynecology at Integral Institute of Medical Sciences and Research, Luck now, Uttar Pradesh, India. Data from 422 pregnant women regarding pregnancy were collected from 1st January 2018 to 30th June 2018 by referring the records.Results: Present study included 422 pregnant females in first, second and third trimester. In the present study, majority of the pregnant women belonged to the age group of 20-25 years (49.5%) followed by age group of 26-30 years (35.5%). The prevalence rate of anemia was found to be 57.6%, with moderate anemia being the most common (44.8%)...

Body Dissatisfaction, Perfectionism, and Media Exposure Among Adolescents

Pakistan Journal of Psychological Research

The present study was planned to explore the relationship between body dissatisfaction, perfectio... more The present study was planned to explore the relationship between body dissatisfaction, perfectionism, and media exposure among adolescents. Sample of young adults (N = 376) students including boys (n = 174) and girls (n = 202) of age range from 16 to 21 years (M = 18.2; SD = 1.24) took part in the research. Multidimensional Self-Relations Questionnaire Appearance Scale (Cash, 2000), Perfectionism Inventory (Hill et al., 2004) and Media Exposure list (Hayee, 2012) were used to assess study variables. The outcomes demonstrated that body areas satisfaction has negative connection while appearance orientation has positive association with perfectionism. Young ladies scored high on appearance orientation, overweight preoccupation, self-classified weight, and perfectionism while scored low on appearance evaluation and body areas satisfaction when contrasted with young men. Media exposure moderates the relationship between body areas satisfaction and perfectionism. These results have esse...

Prevalence of hepatitis C among pregnant females attending antenatal clinic at a tertiary care hospital in Lucknow, Uttar Pradesh, India

International Journal of Advances in Medicine

Background: Hepatitis C virus (HCV) is a major causative agent of parenterally acquired hepatitis... more Background: Hepatitis C virus (HCV) is a major causative agent of parenterally acquired hepatitis. Vertical transmission of HCV occurs from mother to infant during pregnancy, delivery, or neonatal period. Hepatitis C infection among pregnant females can adversely affect both mother and fetus, leading to chronic infection in infants who later develop liver cirrhosis and hepatocellular carcinoma. Objective of the study was to evaluate the prevalence of hepatitis C among pregnant females attending antenatal clinic.Methods: A hospital based cross-sectional study was done over a period of six months from January to June 2019. A total of 550 pregnant females were included in the study who attended Antenatal Clinic for routine check-up and whose blood samples were sent to Microbiology Laboratory for screening of anti-HCV antibodies by Enzyme linked Immunosorbent Assay (ELISA) method.Results: Out of 550 pregnant females tested, 3 were found to be reactive to anti-HCV antibodies by ELISA; he...

A study of rate, indications and maternal morbidity associated with cesarean delivery in a tertiary care hospital

International Journal of Reproduction, Contraception, Obstetrics and Gynecology

Background: Cesarean section is one of the most commonly performed surgical procedures in obstetr... more Background: Cesarean section is one of the most commonly performed surgical procedures in obstetrics worldwide. Over the last three decades, a tremendous increase in cesarean section rates has been observed globally, which is a cause for concern as procedure is associated with higher morbidity and mortality compared to vaginal delivery. This study was done to analyze the rate and indications for cesarean section and associated maternal morbidity and mortality.Methods: This retrospective study was conducted over a period of 6 months from 1st October 2017 to 31st March 2018 in the department of Obstetrics and Gynecology, Integral Institute of Medical Sciences and Research, Lucknow, India. Data of patients who were admitted for delivery in department of Obstetrics and Gynecology in OPD or emergency were recorded. Statistical analysis of various parameters namely, the cesarean section rates, its indications, the patient’s morbidity and mortality was done.Results: The total numbers of w...

Seroprevalence of hepatitis B virus surface antigen (HBsAg) among clients visiting ‘Tefera Hailu’ memorial hospital, Sekota, Northern Ethiopia

BMC Infectious Diseases, 2016

Background: Hepatitis B virus is one of the most causative agents of human liver disease, includi... more Background: Hepatitis B virus is one of the most causative agents of human liver disease, including acute and chronic hepatitis, cirrhosis and hepatocellular carcinoma. The disease is a great health problem worldwide, with estimated of 350 million chronically infected people. Objective: The aim of this study was to determine the prevalence of hepatitis B virus in Tefera Hailu Memorial Hospital (THMH) for the last three years (2013, 2014, 2015) by using secondary data. Method: A three year retrospective record review was conducted from March 01/2015-July 30/2015. All registered data for hepatitis B virus serological screening of the specified period were included. The data were collected by predesigned data collection sheet. The sample size was calculated by simple statistical estimation to be 149 for each year. Result: Of 482 subjects, 215 (44.60 %) were females and 267 (55.40 %) were males. The overall prevalence of HBV was 102 (21.16 %). The positivity rate was 69 (14.31 %) in the age group between 15 and 45. There was a decrease in the prevalence of HBV from 2012 up to 2014. Conclusion: The seroprevalence of HBsAg was higher in males than in females and the yearly prevalence decreases from 2012-2014. But HBV infection is still a public health problem in Ethiopia. Therefore intensification of health education concerning modes of transmission and prevention of HBV, early case finding and treatment is recommended to reduce the spread of the disease.

Endometrial Osseous Metaplasia—A Rare Presentation of Polymenorrhagia: A Case Report

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2015

A 41-year-old female presented to the gynecology outpatient department with a history of continuo... more A 41-year-old female presented to the gynecology outpatient department with a history of continuous, excessive bleeding, lower abdominal pain and vaginal discharge for the past two years. She was multiparous and had delivered two children, both vaginally. The last delivery was 14 years back. The patient gave history of dilatation and curettage at 6 weeks of gestation for incomplete abortion, approximately three and a half years back. Despite conventional hormone therapy, the patient was not relieved. She had no other relevant history suggestive of any systemic disorder. On general examination, she appeared normal except mild pallor was observed. Bimanual examination revealed bulky uterus with mild bilateral tenderness. Ultrasound of pelvis revealed presence of hyper echoic foci measuring 9mm and 15×10mm in the uterine cavity [Table/Fig-1]. So, dilatation and curettage was done. During curettage gritty sensation was felt and only scanty tissue was removed and it was subjected to histopathological examination. The report revealed chronic endometritis. The decision for hysterectomy was taken since there was no response to the previous treatment and she had no desire of having more children.

Role of 17 α Hydroxy Progesterone Caproate (17OHPC) in the Prevention of Preterm Labor

The Journal of Obstetrics and Gynecology of India, 2012

Objective To evaluate the role of 17 a hydroxyprogesterone caproate (17OHPC) in the prevention of... more Objective To evaluate the role of 17 a hydroxyprogesterone caproate (17OHPC) in the prevention of preterm labor in high risk asymptomatic patients with a history of preterm delivery. Methods The study included 96 patients with a singleton pregnancy and having a prior preterm birth. They were divided in 2 groups, group I (treatment group) included 46 asymptomatic patients who were given 17OHPC injections starting from 16-20 weeks till 36 weeks and group II (control group) included 50 patients who did not receive any treatment. Results The incidence of preterm delivery was found to be 6.9 %. The median gestational age at delivery was 36 weeks in group I and 33 W5D in controls. 50 % cases in group I and 80 % of controls delivered prematurely in the group with a prior preterm birth between 20-28 weeks. Conclusion In patients who had a prior history of a preterm delivery the recurrence of a preterm birth was less in the treated group as compared to controls. The median gestational age at delivery was significantly higher in 17OHPC treated patients with history of earliest prior preterm delivery at 20-28 weeks.

Morphological, Morphometric, and Histological Evaluation of the Placenta in Cases of Intrauterine Fetal Death

Curēus, Jun 21, 2024

Background The human placenta is a remarkable organ that develops during pregnancy and is crucial... more Background The human placenta is a remarkable organ that develops during pregnancy and is crucial in supporting fetal growth and development. The placenta supplies oxygen and nutrients to the fetus and removes waste products from the fetal bloodstream. It also produces hormones that support pregnancy, such as human chorionic gonadotropin, progesterone, and estrogen. Placental insufficiency occurs when the placenta cannot deliver adequate nutrients and oxygen to the fetus. This can result in intrauterine fetal death (IUFD), stillbirth, intrauterine growth restriction, low birth weight, and premature birth. It can also be associated with developmental delays or long-term health issues for the baby. This study aimed to assess the morphologic, morphometric, and histologic changes in the placenta associated with IUFD and compare it with the placenta of live births.

A study on awareness, knowledge and attitude towards cervical cancer and its prevention among women having cervical abnormalities in Lucknow, India

International Journal of Chemical and Biochemical Sciences, 2024

Étude de l’utilisation de l’inhalateur connecté Connect’inh en vie réelle et de sa pertinence pour répondre aux besoins des patients asthmatiques et atteints de bronchopneumopathie chronique obstructive

Revue D Epidemiologie Et De Sante Publique, Jun 1, 2019

Objectifs Connect’inh est un dispositif connecte developpe par la start-up Kap Code et destine au... more Objectifs Connect’inh est un dispositif connecte developpe par la start-up Kap Code et destine aux patients atteints de pathologies respiratoires chroniques comme l’asthme ou la bronchopneumopathie chronique obstructive (BPCO). Cette etude a ete realisee en condition reelle d’utilisation afin de s’assurer de la pertinence de l’objet pour repondre aux besoins des patients mais aussi pour evaluer au cours du temps le degre d’appropriation de l’objet par les utilisateurs finaux de Connect’inh. Methode L’etude a ete menee avec des patients atteints de pathologies respiratoires (asthme et BPCO) recrutes via les reseaux sociaux (Twitter, Facebook, LinkedIn, Google). Les patients ont ete suivis pendant trois mois. Au total, 42 personnes (18 hommes et 24 femmes) ont participe a l’etude : 14 % avaient entre 18 et 25 ans, 43 % entre 25 et 34 ans, 26 % entre 35 et 49 ans et 17 % plus de 50 ans. Trois questionnaires ont ete administres en ligne : le premier questionnaire avait pour but d’explorer le profil des malades et leurs attentes concernant un objet connecte, avant la prise en main de l’objet Connect’inh. Un deuxieme questionnaire a ete administre une semaine apres la prise en main de l’objet puis, un troisieme apres trois mois d’utilisation. Une analyse statistique a ensuite permis de classifier et mettre en regard les attentes des patients et la reponse aux besoins en vie reelle grâce a l’objet Connect’inh. Resultats L’analyse des questionnaires prealables a pu montrer que 63 % des patients estimaient que le suivi de leur pathologie chronique respiratoire n’etait pas suffisant, et qu’ils souhaitaient un outil adaptable permettant un suivi personnalise (suivi des crises, information sur les traitements de fond ou de crise) couple a des informations sur l’environnement (notification sur la qualite de l’air) ; 100 % des patients ont estime qu’un inhalateur connecte comme Connect’inh pouvait repondre a leurs besoins. Les patients n’ont pas ete reticent a l’utilisation d’un objet connecte ou a l’utilisation de la geolocalisation via l’application, et ce, quel que soit l’âge des participants aux questionnaires. Au final, apres une semaine d’utilisation, 63 % des patients beta-testeurs estimaient que Connect’inh repondait a leurs besoins, et 78 % recommanderaient le produit a une autre personne souffrant d’une pathologie respiratoire chronique. Conclusion Cette etude a permis de s’assurer de la bonne appropriation d’un objet connecte et sa pertinence en condition reelle d’utilisation par des patients atteints de pathologies respiratoires. L’analyse des donnees met en evidence que les patients asthmatiques et/ou atteints de BPCO sont aujourd’hui en majorite demandeurs de davantage de suivi pour leur pathologie respiratoire, et qu’un objet connecte pourrait etre un moyen d’y parvenir. Dans les conditions reelles d’utilisation, les patients ont estime que Connect’inh pouvait repondre a leurs besoins. Un suivi a plus long terme sera necessaire pour s’assurer de l’appropriation de l’inhalateur connecte dans la duree et s’interesser a l’impact d’un tel dispositif sur la frequence et la gravite des crises.

Contraceptive awareness, and practices among rural women in Lucknow

Indian Journal of Obstetrics and Gynecology Research, Dec 15, 2020

Objective: This cross sectional observational study was done to asses awareness regarding family ... more Objective: This cross sectional observational study was done to asses awareness regarding family planning methods and the practice of contraceptives among rural women in Lucknow. Materials and Methods: Five hundred women between the ages of 15-45 years, living with their husbands and coming from rural area, attending gynecology OPD of integral institute of medical sciences and research, Dasauli, Lucknow were included in this study. Women who were pregnant, had a child younger than 2 years, or had any medical disorder were excluded. Their knowledge, source of knowledge and practice of contraceptives were evaluated with the help of a predesigned questionnaire. The other variables used were the age of women, parity, religion and educational status. Results were expressed as percentages. Results: Out of 500 interviewed majority of women (49.2%) were between 22-25 years of age. 61% were illiterate belonging to low socioeconomic status, 63.3% belonged to Hindu religion. In the present study, it was observed that, 94.4% had some knowledge about family planning methods, and almost all (94.4%) of them were aware about Cu T and oral pills. The media and social circle were provided information of contraceptives in 46.6% women. Regarding the usage of contraceptive methods, 41.2% of the respondents were using some sort of contraception. Barrier method (condoms) was in practice by 26.8%, pills in 5.6%. Cu T users were 3.2% and 1.2% were using DMPA for contraception. 4.4% of women had already undergone tubal ligation. It was noted that awareness about pills and Copper was good, but their practices were very low. There were multiple reasons for non use like fear of side effects, no support from the husbands, low fertility, inhibition to ask about the contraceptives. Conclusion: There is need for strong motivation of couples through media and health personnel to achieve effective use of contraceptives, specially for Cu T and oral pills.

Awareness of cervical cancer risk factors and screening methods among women attending a tertiary hospital in Lucknow, India

International journal of reproduction, contraception, obstetrics and gynecology, Nov 23, 2017

Cancer cervix is the second most common cancer among women after breast cancer worldwide. Accordi... more Cancer cervix is the second most common cancer among women after breast cancer worldwide. According to WHO, cancer cervix comprises 12% of all cancers in women and is the leading gynaecological malignancy in the world. In contrast to developed countries, cancer cervix is a major public health problem in developing countries like India. India alone accounts for one-quarter of the worldwide burden of cervical cancers. 1,2 It is one of the leading cause of cancer related deaths, accounting for 17% of all cancer deaths among women aged between 30 and 69 years. It is estimated that cancer cervix will occur in approximately 1 in 53 Indian women during their lifetime compared with 1 in 100 women in more developed regions of the world.

Seroprevalence of Hepatitis B virus surface antigen among pregnant females attending antenatal clinic at a tertiary care hospital in North India

International Journal of Research in Medical Sciences, Dec 25, 2019

Background: Hepatitis B infection is one of the most common public health problems worldwide. Hep... more Background: Hepatitis B infection is one of the most common public health problems worldwide. Hepatitis B virus Surface Antigen (HBsAg) positive mothers may transmit the virus vertically to neonates transplacentally during pregnancy, perinatally during delivery or postnatally through breast milk. Such neonates being carriers of virus are at a very high risk of developing chronic liver diseases at a younger age and also, they act as reservoirs of infection in the community. Objective of the study is to evaluate the seroprevalence of HBsAg in pregnant females attending Antenatal Clinic. Methods: A hospital based cross-sectional study was done from January to June 2019. A total of 840 pregnant females were included in the study who attended Antenatal Clinic for routine checkup whose blood samples were sent to Microbiology Laboratory for screening of HBsAg by Enzyme Linked Immunosorbent Assay (ELISA). Results: Out of 840 pregnant females included in the study, 8 were reactive to HBsAg, hence, prevalence was found to be 0.95%. The seroprevalence of HBsAg was found to be more (1.40%) in 26-35 year females. Maximum seropositivity was seen in females from urban areas (1.0%), those attending OPD of ANC (1.03%) and those who belonged to lower socioeconomic class (1.02%). Conclusions: Routine free screening for HBV infection should be offered to all antenatal females to reduce the risk of vertical transmission to the neonates born to infected mothers, thereby, preventing them from becoming carriers and developing chronic hepatitis and hepatocellular carcinoma later in life.

Role of 17 α Hydroxy Progesterone Caproate (17OHPC) in the Prevention of Preterm Labor

The Journal of Obstetrics and Gynecology of India, Aug 1, 2012

Objective To evaluate the role of 17 a hydroxyprogesterone caproate (17OHPC) in the prevention of... more Objective To evaluate the role of 17 a hydroxyprogesterone caproate (17OHPC) in the prevention of preterm labor in high risk asymptomatic patients with a history of preterm delivery. Methods The study included 96 patients with a singleton pregnancy and having a prior preterm birth. They were divided in 2 groups, group I (treatment group) included 46 asymptomatic patients who were given 17OHPC injections starting from 16-20 weeks till 36 weeks and group II (control group) included 50 patients who did not receive any treatment. Results The incidence of preterm delivery was found to be 6.9 %. The median gestational age at delivery was 36 weeks in group I and 33 W5D in controls. 50 % cases in group I and 80 % of controls delivered prematurely in the group with a prior preterm birth between 20-28 weeks. Conclusion In patients who had a prior history of a preterm delivery the recurrence of a preterm birth was less in the treated group as compared to controls. The median gestational age at delivery was significantly higher in 17OHPC treated patients with history of earliest prior preterm delivery at 20-28 weeks.

A Rare Cause of Postpartum Back Ache: Osteitis Condensans Ilii

The Journal of Obstetrics and Gynecology of India

Prevalence of Hepatitis B Infection among Female Patients Attending Integral IMS & Research Hospital, Lucknow

Hepatitis B infection is caused by hepatitis B virus (HBV), an enveloped DNA virus belonging to f... more Hepatitis B infection is caused by hepatitis B virus (HBV), an enveloped DNA virus belonging to family Hepadnaviridae that infects the liver and causes hepatocellular necrosis and inflammation which are serious public health problem worldwide. The Present study was conducted in the department of microbiology on 456 female patients. The serums were obtained by centrifugation & test was done. The Hepatitis B surface Ag was detected by using HEPACARDS kit. In our current study on 456 female patients were screened for HBsAg and we found that 5.3% female patients were reactive with HBsAg in serum and 94.7% were Non reactive with HBsAg out of 456 female patients. Higher prevalence of HBsAg was reported in most sexually active age group.i.e.21-40 years (57.5%) and least in age group 81-100 (0.4%). In the light of current study, it can be concluded that the Hepatitis B contributes significantly to chronic liver diseases in India and being transmitted through parenteral, sexual or perinatal ...

To Evaluate the Effect of 17 Alpha Hydroxyprogesterone Caproate (17OHPC) As a Maintenance Tocolytic in Preterm Labor

Aims & ObjectiveTo evaluate the efficacy of of 17 alpha hyroxyprogesterone caproate after acute t... more Aims & ObjectiveTo evaluate the efficacy of of 17 alpha hyroxyprogesterone caproate after acute tocolysis with nifedipine in preventing preterm delivery. Material & MethodsIt was a prospective clinical trial that was carried out on 100 pregnant females between 2834 weeks of gestation diagnosed with preterm labor pains All patients in pretrm labor were given nifedipine for acute tocolysis and antenatal corticosteroid was given to all patient for lung maturity. After tocolysis undelivered patients were randomly allocated to progesterone(n=50) and control group(n=50).Patients in Progesterone were given 17 alpha hyroxyprogesterone caproate, 250 mg, weekly and continued till 36 weeks of gestation or delivery, which ever occurred earlier. Control group were given nifedipine as a maintanencetocolysis as and when required. Results were analysed in terms of gestational age at delivery and neonatal outcome in both groups. Results-Mean gestational age at delivery was 35.2±2.3 weeks in progeste...

Contraceptive awareness, and practices among rural women in Lucknow

Indian Journal of Obstetrics and Gynecology Research

Objective: This cross sectional observational study was done to asses awareness regarding family ... more Objective: This cross sectional observational study was done to asses awareness regarding family planning methods and the practice of contraceptives among rural women in Lucknow. Materials and Methods: Five hundred women between the ages of 15-45 years, living with their husbands and coming from rural area, attending gynecology OPD of integral institute of medical sciences and research, Dasauli, Lucknow were included in this study. Women who were pregnant, had a child younger than 2 years, or had any medical disorder were excluded. Their knowledge, source of knowledge and practice of contraceptives were evaluated with the help of a predesigned questionnaire. The other variables used were the age of women, parity, religion and educational status. Results were expressed as percentages. Results: Out of 500 interviewed majority of women (49.2%) were between 22-25 years of age. 61% were illiterate belonging to low socioeconomic status, 63.3% belonged to Hindu religion. In the present study, it was observed that, 94.4% had some knowledge about family planning methods, and almost all (94.4%) of them were aware about Cu T and oral pills. The media and social circle were provided information of contraceptives in 46.6% women. Regarding the usage of contraceptive methods, 41.2% of the respondents were using some sort of contraception. Barrier method (condoms) was in practice by 26.8%, pills in 5.6%. Cu T users were 3.2% and 1.2% were using DMPA for contraception. 4.4% of women had already undergone tubal ligation. It was noted that awareness about pills and Copper was good, but their practices were very low. There were multiple reasons for non use like fear of side effects, no support from the husbands, low fertility, inhibition to ask about the contraceptives. Conclusion: There is need for strong motivation of couples through media and health personnel to achieve effective use of contraceptives, specially for Cu T and oral pills.

Awareness of cervical cancer risk factors and screening methods among women attending a tertiary hospital in Lucknow, India

International Journal of Reproduction, Contraception, Obstetrics and Gynecology

Background: Cervical cancer is the second most common cancers among women worldwide after breast ... more Background: Cervical cancer is the second most common cancers among women worldwide after breast cancer. It is the only cancer in which early diagnosis of precancerous lesions can be done by a very simple and sensitive test that is, paps test. Knowledge of the women about cervical cancer risk factors and awareness about its screening are the key factors that may decrease the mortality and morbidity caused by cancer cervix. Most of the cases of cervical cancer in India are diagnosed very late, because of lack of awareness about risk factors and screening methods, resulting in fatal outcome. So, this study was done to assess the knowledge of risk factors for cervical cancer, and paps smear test for its screening.Methods: This cross-sectional study was conducted among 200 women aged 18-55 years, attending Gynaecology Out-Patient Department (OPD) in a tertiary care hospital in Lucknow. Information about their knowledge of cervical cancer, awareness of its prevention and their socio demo...

Prevalence of anemia in pregnancy at booking: a retrospective study at a tertiary care centre in Lucknow India

International Journal of Reproduction, Contraception, Obstetrics and Gynecology

Background: Anemia in pregnancy is one of the most common nutritional deficiency disorders affect... more Background: Anemia in pregnancy is one of the most common nutritional deficiency disorders affecting the pregnant women in the developing countries. The aim of our study was to understand the prevalence of anemia among pregnant women, and factors associated with anemia.Methods: It was a retrospective record based study conducted in pregnant women, attending antenatal clinic and emergency in the Department of Obstetrics and Gynecology at Integral Institute of Medical Sciences and Research, Luck now, Uttar Pradesh, India. Data from 422 pregnant women regarding pregnancy were collected from 1st January 2018 to 30th June 2018 by referring the records.Results: Present study included 422 pregnant females in first, second and third trimester. In the present study, majority of the pregnant women belonged to the age group of 20-25 years (49.5%) followed by age group of 26-30 years (35.5%). The prevalence rate of anemia was found to be 57.6%, with moderate anemia being the most common (44.8%)...

Body Dissatisfaction, Perfectionism, and Media Exposure Among Adolescents

Pakistan Journal of Psychological Research

The present study was planned to explore the relationship between body dissatisfaction, perfectio... more The present study was planned to explore the relationship between body dissatisfaction, perfectionism, and media exposure among adolescents. Sample of young adults (N = 376) students including boys (n = 174) and girls (n = 202) of age range from 16 to 21 years (M = 18.2; SD = 1.24) took part in the research. Multidimensional Self-Relations Questionnaire Appearance Scale (Cash, 2000), Perfectionism Inventory (Hill et al., 2004) and Media Exposure list (Hayee, 2012) were used to assess study variables. The outcomes demonstrated that body areas satisfaction has negative connection while appearance orientation has positive association with perfectionism. Young ladies scored high on appearance orientation, overweight preoccupation, self-classified weight, and perfectionism while scored low on appearance evaluation and body areas satisfaction when contrasted with young men. Media exposure moderates the relationship between body areas satisfaction and perfectionism. These results have esse...

Prevalence of hepatitis C among pregnant females attending antenatal clinic at a tertiary care hospital in Lucknow, Uttar Pradesh, India

International Journal of Advances in Medicine

Background: Hepatitis C virus (HCV) is a major causative agent of parenterally acquired hepatitis... more Background: Hepatitis C virus (HCV) is a major causative agent of parenterally acquired hepatitis. Vertical transmission of HCV occurs from mother to infant during pregnancy, delivery, or neonatal period. Hepatitis C infection among pregnant females can adversely affect both mother and fetus, leading to chronic infection in infants who later develop liver cirrhosis and hepatocellular carcinoma. Objective of the study was to evaluate the prevalence of hepatitis C among pregnant females attending antenatal clinic.Methods: A hospital based cross-sectional study was done over a period of six months from January to June 2019. A total of 550 pregnant females were included in the study who attended Antenatal Clinic for routine check-up and whose blood samples were sent to Microbiology Laboratory for screening of anti-HCV antibodies by Enzyme linked Immunosorbent Assay (ELISA) method.Results: Out of 550 pregnant females tested, 3 were found to be reactive to anti-HCV antibodies by ELISA; he...

A study of rate, indications and maternal morbidity associated with cesarean delivery in a tertiary care hospital

International Journal of Reproduction, Contraception, Obstetrics and Gynecology

Background: Cesarean section is one of the most commonly performed surgical procedures in obstetr... more Background: Cesarean section is one of the most commonly performed surgical procedures in obstetrics worldwide. Over the last three decades, a tremendous increase in cesarean section rates has been observed globally, which is a cause for concern as procedure is associated with higher morbidity and mortality compared to vaginal delivery. This study was done to analyze the rate and indications for cesarean section and associated maternal morbidity and mortality.Methods: This retrospective study was conducted over a period of 6 months from 1st October 2017 to 31st March 2018 in the department of Obstetrics and Gynecology, Integral Institute of Medical Sciences and Research, Lucknow, India. Data of patients who were admitted for delivery in department of Obstetrics and Gynecology in OPD or emergency were recorded. Statistical analysis of various parameters namely, the cesarean section rates, its indications, the patient’s morbidity and mortality was done.Results: The total numbers of w...

Seroprevalence of hepatitis B virus surface antigen (HBsAg) among clients visiting ‘Tefera Hailu’ memorial hospital, Sekota, Northern Ethiopia

BMC Infectious Diseases, 2016

Background: Hepatitis B virus is one of the most causative agents of human liver disease, includi... more Background: Hepatitis B virus is one of the most causative agents of human liver disease, including acute and chronic hepatitis, cirrhosis and hepatocellular carcinoma. The disease is a great health problem worldwide, with estimated of 350 million chronically infected people. Objective: The aim of this study was to determine the prevalence of hepatitis B virus in Tefera Hailu Memorial Hospital (THMH) for the last three years (2013, 2014, 2015) by using secondary data. Method: A three year retrospective record review was conducted from March 01/2015-July 30/2015. All registered data for hepatitis B virus serological screening of the specified period were included. The data were collected by predesigned data collection sheet. The sample size was calculated by simple statistical estimation to be 149 for each year. Result: Of 482 subjects, 215 (44.60 %) were females and 267 (55.40 %) were males. The overall prevalence of HBV was 102 (21.16 %). The positivity rate was 69 (14.31 %) in the age group between 15 and 45. There was a decrease in the prevalence of HBV from 2012 up to 2014. Conclusion: The seroprevalence of HBsAg was higher in males than in females and the yearly prevalence decreases from 2012-2014. But HBV infection is still a public health problem in Ethiopia. Therefore intensification of health education concerning modes of transmission and prevention of HBV, early case finding and treatment is recommended to reduce the spread of the disease.

Endometrial Osseous Metaplasia—A Rare Presentation of Polymenorrhagia: A Case Report

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2015

A 41-year-old female presented to the gynecology outpatient department with a history of continuo... more A 41-year-old female presented to the gynecology outpatient department with a history of continuous, excessive bleeding, lower abdominal pain and vaginal discharge for the past two years. She was multiparous and had delivered two children, both vaginally. The last delivery was 14 years back. The patient gave history of dilatation and curettage at 6 weeks of gestation for incomplete abortion, approximately three and a half years back. Despite conventional hormone therapy, the patient was not relieved. She had no other relevant history suggestive of any systemic disorder. On general examination, she appeared normal except mild pallor was observed. Bimanual examination revealed bulky uterus with mild bilateral tenderness. Ultrasound of pelvis revealed presence of hyper echoic foci measuring 9mm and 15×10mm in the uterine cavity [Table/Fig-1]. So, dilatation and curettage was done. During curettage gritty sensation was felt and only scanty tissue was removed and it was subjected to histopathological examination. The report revealed chronic endometritis. The decision for hysterectomy was taken since there was no response to the previous treatment and she had no desire of having more children.

Role of 17 α Hydroxy Progesterone Caproate (17OHPC) in the Prevention of Preterm Labor

The Journal of Obstetrics and Gynecology of India, 2012

Objective To evaluate the role of 17 a hydroxyprogesterone caproate (17OHPC) in the prevention of... more Objective To evaluate the role of 17 a hydroxyprogesterone caproate (17OHPC) in the prevention of preterm labor in high risk asymptomatic patients with a history of preterm delivery. Methods The study included 96 patients with a singleton pregnancy and having a prior preterm birth. They were divided in 2 groups, group I (treatment group) included 46 asymptomatic patients who were given 17OHPC injections starting from 16-20 weeks till 36 weeks and group II (control group) included 50 patients who did not receive any treatment. Results The incidence of preterm delivery was found to be 6.9 %. The median gestational age at delivery was 36 weeks in group I and 33 W5D in controls. 50 % cases in group I and 80 % of controls delivered prematurely in the group with a prior preterm birth between 20-28 weeks. Conclusion In patients who had a prior history of a preterm delivery the recurrence of a preterm birth was less in the treated group as compared to controls. The median gestational age at delivery was significantly higher in 17OHPC treated patients with history of earliest prior preterm delivery at 20-28 weeks.