Papers by Natalie Antinoff
Advancing and Promoting Avian Medicine and Stewardship
Advances in Small Animal Medicine and Surgery, 2004
Journal of Avian Medicine and Surgery
Current Therapy in Avian Medicine and Surgery
Osteomyelitis is a frequently recognized syndrome in reptiles. There are many contributing factor... more Osteomyelitis is a frequently recognized syndrome in reptiles. There are many contributing factors, and treatment in most cases will vary based on the inciting cause, areas affected, organisms involved, and patient and owner compliance. Rapid diagnosis and aggressive treatment are essential to affect a cure.
Journal of Avian Medicine and Surgery, 2020
Abstract: A 17-year-old, female cockatiel (Nymphicus hollandicus) was presented for a 1-week hist... more Abstract: A 17-year-old, female cockatiel (Nymphicus hollandicus) was presented for a 1-week history of respiratory distress. The clinical signs were consistent with tracheal obstruction; therefore, an air sac cannula was placed to reduce respiratory compromise. Radiographic images of the patient revealed a round, intraluminal, soft tissue opacity in the trachea. The obstruction could be visualized via transtracheal illumination, but tracheoscopy was not feasible because of the size of the patient. Attempts to manually extirpate the obstruction were unsuccessful, and the trachea subsequently avulsed in the midcervical region. Tracheal resection and anastomosis was performed, and the obstruction was removed with the associated tracheal ring. The patient recovered uneventfully and was doing well at follow-up evaluations at 9 days, 24 days, and 10 months after the surgical procedure. The histologic diagnosis was ossifying myelolipoma arising from bone marrow within the tracheal ring.
Journal of Clinical Microbiology, 1996
Mycobacterium genavense, a recently reported cause of a wasting illness in patients with AIDS, wa... more Mycobacterium genavense, a recently reported cause of a wasting illness in patients with AIDS, was isolated from a cervical lymph mode from a dog with severe hind limb weakness and from trachael tissue from a parrot with acute onset respiratory distress. Physicians caring for immunocompromised patients should consider birds and dogs potential sources of M. genavense infection and submit appropriate specimens for culture.
Journal of Exotic Pet Medicine, 2019
Presentation and survival time of domestic ferrets (Mustela putorius furo) with lymphoma treated ... more Presentation and survival time of domestic ferrets (Mustela putorius furo) with lymphoma treated with single-and multi-agent protocols: 44 cases (1998-2016).
Journal of Exotic Pet Medicine, 2019
A 4.5-year-old female spayed Rex rabbit (Oryctolagus cuniculus) was presented as an emergency cas... more A 4.5-year-old female spayed Rex rabbit (Oryctolagus cuniculus) was presented as an emergency case for hyporexia, pigmenturia, and abnormal feces. The rabbit had been treated for intermittent hyporexia with outpatient medical management and over the next two months demonstrated intermittent signs of gastrointestinal stasis, which were only partially responsive to aggressive medical management. Serial radiographs demonstrated persistent gas within the cecum as well as left-sided, cranial displacement of the cecum. A partial cecal obstruction or volvulus was suspected but could not be confirmed, as advanced imaging and exploratory laparotomy were declined. Two months following it's initial presentation, the rabbit developed acute signs of shock and colic, but arrested prior to emergency evaluation. Postmortem radiographs showed marked generalized gas dilation of the small intestines and cecum. Necropsy revealed a 360° mesenteric root torsion with devitalization of much of the small intestines, with an additional 180° rotation of the cecum. This case demonstrates that mesenteric root torsion occurs in rabbits and is an important consideration in rabbits presenting with acute shock or chronic, intractable gastrointestinal signs.
Journal of Exotic Pet Medicine, 2017
A 4-month-old female bearded dragon (Pogona vitticeps) was presented with unilateral conjunctivit... more A 4-month-old female bearded dragon (Pogona vitticeps) was presented with unilateral conjunctivitis. The conjunctivitis was not responsive to topical antibiotic or anti-inflammatory therapy and continued to progress in severity. Conjunctival tissue was sampled and microsporidial conjunctivitis was diagnosed on histopathological evaluation of submitted samples. Medical therapy was initiated and included topical itraconazole, systemic itraconazole, and systemic fenbendazole. Serial serum chemistry panels and complete blood counts were monitored for potential side effects associated with the medications. Despite treatment, the conjunctivitis progressed and enucleation was performed. Histopathology on the enucleated globe confirmed the diagnosis of microsporidial keratoconjunctivitis. Systemic itraconazole was administered at 5 mg/kg orally for approximately 3 months. No abnormalities were detected on hematologic diagnostic testing during the treatment period. A computed tomographic scan was performed to monitor for systemic lesions, but no abnormalities were detected. About 12 months after initial presentation, the bearded dragon is healthy and there are no overt signs of disease.
Veterinary Clinics of North America: Exotic Animal Practice, 1998
Veterinary Clinics of North America: Exotic Animal Practice, 1999
Veterinary Clinics of North America: Exotic Animal Practice, 2000
Ferrets, Rabbits, and Rodents, 2004
The veterinary clinics of North America. Exotic animal practice, 2009
Ferrets, Rabbits, and Rodents, 2012
Journal of Exotic Pet Medicine, 2013
A 4-year-old, castrated, male domestic ferret (Mustela putorius furo) was evaluated for a possibl... more A 4-year-old, castrated, male domestic ferret (Mustela putorius furo) was evaluated for a possible upper respiratory tract infection and wheezing for approximately 3 weeks. Supportive care for a suspected upper respiratory tract infection was initiated; however, the patient became progressively more dyspneic over the next 48 hours. A possible tracheal mass was identified upon thoracic radiographic imaging of the ferret. Tracheoscopy and a computed tomography scan of the neck and thorax confirmed the presence of a tracheal mass approximately 3 cm from the larynx obstructing 80% of the tracheal lumen. Rather than pursuing surgical resection, the owners elected humane euthanasia. An adenosquamous carcinoma of the trachea was diagnosed after histologic analysis. This tumor type has been diagnosed in the lungs of ferrets that were experimentally exposed to carcinogens found in cigarette smoke; however, there are no previous reports of this or any other tumor type associated with the ferret trachea. A tracheal mass causing a partial upper airway obstruction should be considered within the differential disease diagnosis list when a ferret is presented with dyspnea.
Ferrets, Rabbits, and Rodents, 2012
Ferrets with neurologic, musculoskeletal, or systemic disease may present with rear limb weakness... more Ferrets with neurologic, musculoskeletal, or systemic disease may present with rear limb weakness, ataxia/incoordination, or both. Primary neurologic and musculoskeletal disorders are not common in pet ferrets. Clinical signs that appear to be caused by primary neurologic disease, particularly posterior paresis, are frequently manifestations of systemic illness. Therefore a thorough and accurate history and physical examination supported by diagnostic imaging and laboratory testing are essential to establishing a diagnosis, treatment plan, and prognosis. Fracture management is covered in Chapter 33. Neurologic signs in ferrets are often a result of generalized disease, such as heart failure or hypoglycemia. Thus a general health evaluation is important for all neurologic patients. A common cause of posterior paresis is hypoglycemia secondary to a pancreatic beta-cell tumor, or insulinoma (see Chapter 8). Hypoglycemia can also result from food deprivation or anorexia, vomiting, sepsis, neoplasia, severe hepatic disease, or any metabolic disorder. Cardiac disease, hypoxia, anemia, and toxin ingestion can result in weakness, ataxia, or central nervous system (CNS) depression. 5,42 Toxicosis from ibuprofen ingestion has been reported to cause neurologic signs including ataxia, depression, coma, and tremors. 41 Clostridium botulinum type C endotoxin causes signs that include dysphagia, ataxia, salivation, and paresis 12 to 96 hours after ingestion of contaminated food; signs can progress to death if the ferret is untreated. 11 Proliferative bowel disease has been associated with paresis and ataxia. 14 This may also occur secondary to discomfort and physical obstruction of limb movement from diseases such as splenomegaly, a caudal abdominal mass, inguinal or sublumbar lymphadenopathy, cystic calculi, peritonitis, prostatic enlargement, or urinary obstruction. Urinary and fecal incontinence may accompany posterior paresis if the underlying problem affects the caudal lumbar innervation of these structures.
Veterinary Clinics of North America: Exotic Animal Practice, 2004
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Papers by Natalie Antinoff