Papers by Muhammad Nur Habib
ABSTRACTIntroductionRecent advances in G6PD deficiency screening and treatment are rapidly changi... more ABSTRACTIntroductionRecent advances in G6PD deficiency screening and treatment are rapidly changing the landscape of radical cure of vivax malaria available for National Malaria Programs (NMPs). While NMPs await the WHO’s global policy guidance on these advances, they will also need to consider different contextual factors related to the vivax burden, health system capacity, and resources available to support changes to their policies and practices. Therefore, we aim to develop an Options Assessment Toolkit (OAT) that enables NMPs to systematically determine optimal radical cure options for their given environments and potentially reduce decision-making delays. This protocol outlines the OAT development process.MethodsUtilizing participatory research methods, the OAT will be developed in four phases where the NMPs and experts will have active roles in designing the research process and the toolkit. In the first phase, an essential list of epidemiological, health system, and politica...
Empowerment, Apr 8, 2022
Madrasah diniyah is a non formal educational institution that teaches Islamic values.but in reali... more Madrasah diniyah is a non formal educational institution that teaches Islamic values.but in reality the existence of TPQ as a source of learning is still not optima due to the lack of public awareness to become at TPQ which causes a lack of knowlegde of Islamic religion for children in the village of Keling Kalijaga Tengah. So the purpuse of this diniyah program is to increase children's Islamic knowlegde the child in the rivet village. The method used is the method of demonstration and lecture. The result is that after the children are given guidance and practice it immediately, the children easily understand the material presented, and this indirectly has an impact on increasing the Islamic religious ability of children in TPQ, Keling hamlet, Central Kalijaga village.
Currents in Pharmacy Teaching and Learning, 2021
Introduction: The Pharmacy Curriculum Outcomes Assessment (PCOA) is a standardized exam developed... more Introduction: The Pharmacy Curriculum Outcomes Assessment (PCOA) is a standardized exam developed by the National Association of Boards of Pharmacy (NABP) in 2008 to measure the curriculum in relation to student progress. The purpose of the study was to determine the impact of preadmissions and pharmacy school variables on third-year student PCOA performance at a Historically Black College or University (HBCU) College of Pharmacy. Methods: A retrospective analysis was conducted using data from three cohorts of students who took the PCOA in their third professional year from 2015 to 2017. An independent samples t-test, correlation analysis, and multivariate linear regression were conducted to determine the relationship between student characteristics and the PCOA score. Results: The mean PCOA scaled score for the third-year pharmacy students was 349.6 ± 46.20 while the mean Pharmacy College Admission Test (PCAT) percentile was 62.7 ± 14.5. Most students (67%) self-identified as Black and the majority (54.9%) were female. The PCOA scores were correlated with the PCAT percentile (P < .001) and the cumulative grade point average (GPA) through the fall semester of the third professional year (P < .001). After adjusting for other factors, the cumulative GPA through the fall semester of the third professional year (P < .001) and PCAT percentiles (P < .001) remained predictive of students PCOA scores. Conclusions: The cumulative GPA through the third-year fall semester and PCAT percentiles are important factors in helping to predict PCOA scores among third year pharmacy students at a HBCU.
Cogent Medicine, 2019
as soon as possible after acceptance. Copyediting, typesetting, and review of the resulting proof... more as soon as possible after acceptance. Copyediting, typesetting, and review of the resulting proof will be undertaken on this manuscript before final publication of the Version of Record (VoR). Please note that during production and pre-press, errors may be discovered which could affect the content.
Cureus, 2019
Wheat pill and its active ingredient aluminum phosphide is one of the emerging causes of poisonin... more Wheat pill and its active ingredient aluminum phosphide is one of the emerging causes of poisoning. The areas mainly hit are the ones where agriculture is the leading industry. The mechanism of action involves phosphine gas, which is released when the pill comes in contact with moisture or stomach acid; the resulting free radicals damage mitochondria. The cardiovascular system is the most severely hit with various presentations, including cardiac failure, arrhythmias, and eventually shock. We discuss a case of a middle-aged woman who suffered from inhalational poisoning from wheat pill while she was working in unventilated grain storage.
Micromachines, Jan 11, 2018
Despite the fact that two-dimensional layered magnetic materials hold immense potential applicati... more Despite the fact that two-dimensional layered magnetic materials hold immense potential applications in the field of spintronic devices, tunable magnetism is still a challenge due to the lack of controllable synthesis. Herein, high-quality single crystals MPS₃ (M= Mn, Fe) of millimeter size were synthesized through the chemical vapor transport method. After systemic structural characterizations, magnetic properties were studied on the bulk MPS₃ layers through experiments, along with first principle theoretical calculations. The susceptibilities as well as the EPR results evidently revealed unique isotropic and anisotropic behavior in MnPS₃ and FePS₃ crystals, respectively. It is worth noting that both of these materials show antiferromagnetic states at measured temperatures. The estimated antiferromagnetic transition temperature is 78 K for bulk MnPS₃ and 123 K for FePS₃ crystals. The spin polarized density functional theory calculations confirmed that the band gap of the antiferrom...
Value in Health, 2006
The nation's largest single provider of health care to those infected with Human Immunodeficiency... more The nation's largest single provider of health care to those infected with Human Immunodeficiency Virus (HIV) is the Department of Veterans Affairs (VA). The clinical effectiveness of highly active antiretroviral therapy (HAART) depends considerably on an individual's ability to adhere closely to therapy. The objective of this study was to assess the relationship between patient adherence to HAART and the costeffectiveness of HAART in antiretroviral-naïve HIV-infected VA patients. METHODS: The overall design of the study is a hybrid between an observational study and a decision-analytic model. Kaplan-Meier survival estimates, calculated from the VA's laboratory and clinical data, were used to model HIV-disease progression. Pharmacy-based adherence was calculated using refill percent adherence obtained from prescription records; individuals were categorized as adherent if adherence was equal to or greater than 95%. Inpatient and outpatient costs were derived from the VA Health Economics Resource Center estimates. Outpatient prescription costs were obtained from the VA's Pharmacy Benefits Management database. Markov Monte Carlo simulations were conducted to project the cost-effectiveness of adherence to HAART. Costs and quality-adjusted life-years (QALY) were discounted at 3%. RESULTS: For the five-year Markov Monte Carlo simulations, the overall costs of adherent behavior were lower than those of non-adherent behavior. In addition, the
Molecules (Basel, Switzerland), Jan 30, 2016
In this work we directly synthesized molybdenum disulfide (MoS₂) nanosheets on carbon nanotube fi... more In this work we directly synthesized molybdenum disulfide (MoS₂) nanosheets on carbon nanotube film (MoS₂@CNT) via a two-step chemical vapor deposition method (CVD). By etching the obtained MoS₂@CNT into 10% wt HNO₃, the morphology of MoS₂ decorated on CNT bundles was modulated, resulting in more catalytic active MoS₂ edges being exposed for significantly enhanced electrochemical performance. Our results revealed that an 8 h acid etching sample exhibited the best performance for the oxygen evolution reaction, i.e., the current density reached 10 mA/cm² under 375 mV over-potential, and the tafel slope was as low as 94 mV/dec. The enhanced behavior was mainly originated from the more catalytic sites in MoS₂ induced by the acid etching treatment and the higher conductivity from the supporting CNT films. Our study provides a new route to produce two-dimensional layers on CNT films with tunable morphology, and thus may open a window for exploring its promising applications in the fields ...
Transportation Research Record: Journal of the Transportation Research Board, 2015
This paper presents the spatial transferability analysis of a micro-behavioral model from the res... more This paper presents the spatial transferability analysis of a micro-behavioral model from the residential mobility component of the integrated land use, transportation, and environment (ILUTE) modeling system developed and implemented in the Greater Toronto and Hamilton Area, Ontario, Canada. The study examined whether ILUTE could be spatially transferred with the current model components to a different geographic area: Halifax, Nova Scotia, Canada. The residential mobility component within ILUTE is a continuous-time, hazard-based duration model, developed with retrospective survey data from the Residential Mobility Survey 2 in the Greater Toronto and Hamilton Area. This study developed a similar continuous-time, hazard-based duration model for the residential mobility decisions of households in Halifax on the basis of retrospective survey data from a household mobility and travel survey. The model results suggested that households in Halifax and the Greater Toronto and Hamilton Are...
The aim of this paper is to utilize repeated cross-sectional data in a pseudo panel data approach... more The aim of this paper is to utilize repeated cross-sectional data in a pseudo panel data approach to investigate an individual’s daily participation in out-of home discretionary activities. The pseudo panel data approach methodology using repeated cross sectional data of the General Social Survey (GSS) conducted by Statistics Canada over the period of 1992-2010 has been applied to conduct longitudinal activity participation in out-of-home discretionary activities. In this study, participation in out-of-home discretionary activities has been calculated using an individual’s participation in shopping, grocery, social, recreational, entertainment and organizational activities per surveyed year. Based on gender and the birth year of the respondent, cohorts are defined and are traced over time in each of the cross sectional data sets. A random coefficient model has been developed on the basis of the cohort data. The estimation of the random coefficient model of the pseudo panel data suggests that personal and household socio- demographic characteristics of have long run effect on out-of-home discretionary activity participations. Model results also show that there is no significant difference between male and female cohorts over the years in terms of out-of-home discretionary activity participation. Travel behavior characteristics (e.g. number of trips per day, total duration of work) also found to have significant variation between cohorts over the years. As the pseudo panel approach has been increasingly applied in travel demand analysis, thus this paper gives an insight to implement pseudo panel for activity travel participation
The effect of feeding frequency on the growth performance and survival of gold fish Carassius aur... more The effect of feeding frequency on the growth performance and survival of gold fish Carassius auratus fry was investigated in the outdoor rearing condition. A total of 135 gold fish fry of 7 days old (initial weight = 0.17±0.00 g) were stocked at the rate of 15 fry/hapa (90×45×60 cm 3) and reared for 35 days set in a pond adjacent to the Faculty of Fisheries. There were three treatments: T1 (feeding once daily), T2 (feeding twice daily) and T3 (feeding thrice daily) each having three replications with same stocking densities. A commercial diet in powdered form (Mega feed; Spectra Hexa Feeds Ltd) containing 34.11% protein was supplied to the fry in each hapa. Initially, the fry were fed at a rate of 100% of their body weight, then the rate was minimized gradually to 80%, 60%, 40%, and 20% respectively at 7 days interval. At the end of experiment, T3 showed the best performance in case of final body weight, percent body weight, specific growth rate (SGR) and survival of gold fish fry in outdoor nursing condition. The present study suggested that a higher feeding frequency is needed for aquarium suitable gold fish production in large scale basis that will ultimately popularize the ornamental fish keeping among the enthusiastic people.
Transportation Research Record: Journal of the Transportation Research Board, 2013
This paper investigates the frequency and the duration of participation in physical activity by c... more This paper investigates the frequency and the duration of participation in physical activity by children who go to school in the city of Dhaka, Bangladesh. The study uses data from a 2012 activity-based travel diary survey of 245 students in Grades 6 to 10 in the Dhaka metropolitan area. To explore the trade-offs between factors that affect the frequency of out-of-home physical activity, including the use of active transportation, this study used a zero-inflated Poisson (ZIP) regression model. Additionally, parametric hazard models were estimated to examine the duration of physical activities. The results of the ZIP count model suggest that personal and household characteristics, attributes of the built environment, and time commitments for other mandatory and discretionary activities influence the frequency of participation in physical activity. For example, an increase in the number of children in the household and the presence of sidewalks increased the frequency of out-of home, ...
Transportation Research Record: Journal of the Transportation Research Board, 2008
This paper presents housing price models by using multilevel modeling techniques. The key motivat... more This paper presents housing price models by using multilevel modeling techniques. The key motivation of using the multilevel modeling technique is that it clearly identifies and differentiates between-cluster heterogeneity (i.e., intrinsic differences across aggregated units) and heterogeneity between units of analysis that are nested within aggregated clusters. Two different specifications are tested: two-level spatial and mixed two-level spatiotemporal random effects models. Whereas the first specification assumes that dwelling units are nested within spatial clusters (i.e., neighborhoods), the second specification hypothesizes that dwelling units are nested within spatiotemporal clusters (neighborhoods in a given time period). The unique contribution of this paper is that it accounts for temporal heterogeneity simultaneously with spatial heterogeneity in the housing price models. The study uses an extensive sample of more than 250,000 housing property transactions in 1987–1995 in...
Transportation Research Record: Journal of the Transportation Research Board, 2009
This paper presents a reference-dependent model for residential location choice. The key contribu... more This paper presents a reference-dependent model for residential location choice. The key contribution of the model is its incorporation of reference dependence that explicitly recognizes the role of the status quo and captures asymmetric responses toward gains and losses in making location choice decisions. The study uses a retrospective residential search survey and a dwelling supply data set from the Toronto Real Estate Board in Ontario, Canada, to estimate the model at the elemental level of individual dwelling units. The study applies a mixed logit formulation that captures unobserved heterogeneity and avoids imposing independence of irrelevant alternatives restrictions on the choice probabilities. Several types of variables, including dwelling characteristics, land uses and other zonal attributes, accessibility measures, and household socio-demographics, are tested in the model. Although the current dwelling is assumed to be the reference point in framing evaluation of alternat...
Transportation Research Record: Journal of the Transportation Research Board, 2011
This paper presents a comprehensive framework for modeling continuous decisions about changing jo... more This paper presents a comprehensive framework for modeling continuous decisions about changing jobs that individuals make over the course of their lives. The key objective of the research was to develop disaggregate econometric models for decision making about job mobility and location choice to implement longitudinal job mobility behavior of people within a dynamic microsimulation-based integrated urban modeling system. The paper includes two behavioral model components: (a) a job mobility model and (b) a job location choice model. The models were implemented empirically with a retrospective survey of the greater Toronto and Hamilton area in Ontario, Canada. The first component investigated the timing of job mobility with the use of a competing risk duration modeling approach for four event types: a job switch, a return to school, short-term unemployment, and withdrawal from the labor force. The second component, job location choice, was empirically estimated by applying the discre...
Tetrahedron, 1964
Abstract Base catalysed intramolecular cyclization of α-cyano- o -nitroacetanilides (Ia–d) to the... more Abstract Base catalysed intramolecular cyclization of α-cyano- o -nitroacetanilides (Ia–d) to the corresponding 2-cyano-3-hydroxyquinoxaline 1-oxides (IIa-d) is described, and a mechanism proposed. The cyanoquinoxaline N-oxides (IIa-d) on reduction are deoxygenated with simultaneous loss of the nitrile group, and when heated with concentrated aqueous alkali the nitrile group is replaced quantitatively by an hydroxyl group.
Pharmaceutical Development and Technology, 1998
The purpose of this study was to enhance the dissolution of mefenamic acid (MFA) through the form... more The purpose of this study was to enhance the dissolution of mefenamic acid (MFA) through the formation of solid dispersion systems, and to compare the dissolution of the unformulated dispersions with those of formulated dispersions in tablets. Solid dispersions of MFA were prepared in polyethylene glycol 3350 (PEG) as a binary system, and PEG and Tween 20 (TW) as a ternary system by the melt method. The dispersions were characterized by dissolution, scanning electron microscopy, and powder x-ray diffraction studies. A decrease in MFA composition in the binary dispersion systems from 50 to 5% w/w resulted in a 50% increase in the dissolution rate during the period of study, and this was threefold higher than that of pure MFA. Incorporation of TW in the preparation of ternary dispersion systems resulted in a further increase in MFA dissolution. A sevenfold increase in MFA dissolution was observed when the ternary system composition was MFA/PEG/TW 4.7:93:2.3 (% w/w). Scanning electron microscopy and x-ray diffraction pictures showed an increase in size and decrease in crystallinity of the dispersions, respectively. Compression of the dispersions into tablets did not have any effect on the dissolution of the drug from the dispersions. Compression of pure MFA and Avicel PH 101, which was used as a diluent and disintegrant, resulted in a threefold increase in dissolution. However, the dissolution of the uncompressed mixture was identical to that of pure MFA. Thus, further processing of the solid dispersions into tablets did not decrease the rate of dissolution of the drug in the dispersions. This may be very important in the formulation of solid dispersions as tablets, which could lead to a reduction in the dose of practically water-insoluble drugs.
The Journal of Organic Chemistry, 1966
... (14) A. Risaliti, Rtc. Sci., 24, 2361 (1954). (15) E. Hayaahi, 0. Iijima. and Y. Nagaaawa. ..... more ... (14) A. Risaliti, Rtc. Sci., 24, 2361 (1954). (15) E. Hayaahi, 0. Iijima. and Y. Nagaaawa. ... I. Phenanthridizinium Perchlorates&amp;#x27; R. E. DOOLITTLE AND CK BRADSHER Department of Chemistry, Duke University, Durham, North Carolina Received March 1.6, 1966 ...
The Journal of Organic Chemistry, 1968
Quinoxaline 1-oxides, bearing a substituent at (3-2, a carbonyl at C-3, and a free hydrogen a t N... more Quinoxaline 1-oxides, bearing a substituent at (3-2, a carbonyl at C-3, and a free hydrogen a t N-4, when heated with acetic anhydride, are transformed into l-acetyl-3-acyl-2-benzimidazolinones or 1,3-diacetyl-2-benzimidazolinones. In the absence of a carbonyl at C-3, the quinoxaline 1-oxides fail to rearrange. On the other hand, if the hydrogen at N-4 is replaced by a methyl, a different type of rearrangement1*J*4 takes place and an acetoxy group is introduced at C-6 in the quinoxaline molecule with simultaneous loss of the N-oxide function. A mechanism for this novel rearrangement has been proposed and discussed. Derivatives of 3-hydroxyquinoxaline 1-oxide6 bearing a substituent at position 2 possess some special structural features. As in such simple and mild reactions as heating with acetyl chloride or ethanolic hydrogen chloride, these compounds undergo chlorination at C-6 of the molecule. In earlier s t u d i e~'~*~?~ it has been shown that this chlorination takes place through the attack of the reagent on the oxygen function at C-3 and the N-oxide, whereby C-6 becomes electron deficient and hence prone to the attack by the chloride anions. The oxygen function at (2-3 seems to be essential for this nucleophilic chlorine substitution at (3-6, as in its absence no reaction takes place. In the present study it was considered of interest to replace acetyl chloride with acetic anhydride and to see if by the same analogy an acetoxy group could be introduced at C-6. When 3-hydroxy-2-phenylquinoxaline 1-oxide (Ia) was heated under reflux with acetic anhydride for 4 hr, a compound was obtained in good yield, which corresponded in composition to CleH12N203 of 6-acetoxy-3-hydroxy-2-phenylquinoxaline (IX, H for Me). However, after hydrolysis with alkali, the deacetylated compound proved to be quite different from the expected 3,6-dihydroxy-2-phenylquinoxaline (X, H for Me). It finally proved to be identical with 2-benzimidazolinone (VIa), an authentic sample of which was obtained by the condensation of o-phenylenediamine and urea. The formation of VIa suggested that the product obtained by the action of acetic anhydride on I a was l-acetyl-3-benzoyl-2-benzimidazolinone (IIIa), which was isomeric with IX (H for Me) and which on hydrolysis lost both acetyl and benzoyl groups. Benzoic acid was also isolated. Similarly 7-ethoxy-3-hydroxy-2-phenylquinoxaline 1oxide (Ib) and 3-hydroxy-7-methyl-2-phenylquinoxaline 1-oxide (Id) on being heated with acetic anhydride under reflux for 4 hr yielded 5-ethoxy-and 5-methyl-lacetyl-3-benzoyl-2-benzimidazolinone (IIIb and IIId), respectively, which on hydrolysis with aqueous alkali lost their acetyl and benzoyl groups and yielded 5-(1) (a)
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Papers by Muhammad Nur Habib