ABSTRACT. The production of Casein hydrolysate with an extracellular proteinase from Lactobacillu... more ABSTRACT. The production of Casein hydrolysate with an extracellular proteinase from Lactobacillus helveticus CP790, was fractionated by two-step reverse phase heigh performance liquid chromatography. Only 1 fraction showed antihypertensive activity as measured by systolic blood pressure in spontaneously hypertensive rats after oral adsministration. Ten peptides in the fraction were further purified and identified by analisys of amino acid sequences. Each identified peptide was chemically synthesized, and the ant.ihypertensive activity of each peptide was evaluated in spontaneously hypertensive rats. The synthetic peptide with a sequence of Lys-Val-Leu-Pro-Val-Pro-Gln, found in β-casein, indicated strong antihypertensive activity from 2 to 10 h after oral adsministration of 2 mg of peptide/kg of BW, and the effect was maximal at 6 h after oral adsministration. Moreover, the antihypertensive effect of the peptide was dependent on the dosage of peptide from 0.5 to 2 mg o peptide/kg of...
Pertama kali kami memanjatkan rasa syukur ke hadirat Allah Subhanahu Wata'la bahwasanya penyusuna... more Pertama kali kami memanjatkan rasa syukur ke hadirat Allah Subhanahu Wata'la bahwasanya penyusunan buku dengan judul "Bahasa Pemrograman " ini dapat diselesaikan. Kerja keras yang telah dilakukan dalam penulisan ini telah membuahkan hasil dengan baik. Buku ini sangat berarti bagi para siswa Sekolah Menengah Kejuruan (SMK) terutama mereka yang mempelajari bidang teknologi informatika dan komunikasi atau bidang lain yang sejenis.
ABSTRACT. The production of Casein hydrolysate with an extracellular proteinase from Lactobacillu... more ABSTRACT. The production of Casein hydrolysate with an extracellular proteinase from Lactobacillus helveticus CP790, was fractionated by two-step reverse phase heigh performance liquid chromatography. Only 1 fraction showed antihypertensive activity as measured by systolic blood pressure in spontaneously hypertensive rats after oral adsministration. Ten peptides in the fraction were further purified and identified by analisys of amino acid sequences. Each identified peptide was chemically synthesized, and the ant.ihypertensive activity of each peptide was evaluated in spontaneously hypertensive rats. The synthetic peptide with a sequence of Lys-Val-Leu-Pro-Val-Pro-Gln, found in β-casein, indicated strong antihypertensive activity from 2 to 10 h after oral adsministration of 2 mg of peptide/kg of BW, and the effect was maximal at 6 h after oral adsministration. Moreover, the antihypertensive effect of the peptide was dependent on the dosage of peptide from 0.5 to 2 mg o peptide/kg of...
Pertama kali kami memanjatkan rasa syukur ke hadirat Allah Subhanahu Wata'la bahwasanya penyusuna... more Pertama kali kami memanjatkan rasa syukur ke hadirat Allah Subhanahu Wata'la bahwasanya penyusunan buku dengan judul "Bahasa Pemrograman " ini dapat diselesaikan. Kerja keras yang telah dilakukan dalam penulisan ini telah membuahkan hasil dengan baik. Buku ini sangat berarti bagi para siswa Sekolah Menengah Kejuruan (SMK) terutama mereka yang mempelajari bidang teknologi informatika dan komunikasi atau bidang lain yang sejenis.
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