Papers by Md. Ali Hossain
International Journal of Environmental Research and Public Health, 2020
Molecular mechanisms underlying the pathogenesis and progression of malignant thyroid cancers, su... more Molecular mechanisms underlying the pathogenesis and progression of malignant thyroid cancers, such as follicular thyroid carcinomas (FTCs), and how these differ from benign thyroid lesions, are poorly understood. In this study, we employed network-based integrative analyses of FTC and benign follicular thyroid adenoma (FTA) lesion transcriptomes to identify key genes and pathways that differ between them. We first analysed a microarray gene expression dataset (Gene Expression Omnibus GSE82208, n = 52) obtained from FTC and FTA tissues to identify differentially expressed genes (DEGs). Pathway analyses of these DEGs were then performed using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) resources to identify potentially important pathways, and protein-protein interactions (PPIs) were examined to identify pathway hub genes. Our data analysis identified 598 DEGs, 133 genes with higher and 465 genes with lower expression in FTCs. We identified four significant p...
Pathogenic mechanisms that underlie malignant follicular thyroid carcinoma (FTC) development are ... more Pathogenic mechanisms that underlie malignant follicular thyroid carcinoma (FTC) development are poorly understood. To identify key genes and pathways driving malignant behaviour we employed a system biology-based integrative analyses comparing FTC transcriptomes with a similar but benign lesion, follicular thyroid adenoma (FTA). We identified differentially expressed genes (DEGs) in microarray gene expression datasets (n=52) of FTCs and FTA tissues. Pathway analyses of DEGs using gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) resources revealed significant pathways, and pathway hub genes using protein-protein interactions (PPI). We identified 598 DEGs (relative to FTAs) in FTCs and 12 significant pathways with altered expression in FTC. 10 GO groups were significantly connected with FTC-high expression DEGs and 80 with low-FTC expression. PPI analysis identified 12 potential hub genes based on degree and betweenness centrality. Moreover, 10 transcription fact...
International Journal of Information Sciences and Techniques, 2013
This paper is concerned with the development of Back-propagation Neural Network for Bangla Speech... more This paper is concerned with the development of Back-propagation Neural Network for Bangla Speech Recognition. In this paper, ten bangla digits were recorded from ten speakers and have been recognized. The features of these speech digits were extracted by the method of Mel Frequency Cepstral Coefficient (MFCC) analysis. The mfcc features of five speakers were used to train the network with Back propagation algorithm. The mfcc features of ten bangla digit speeches, from 0 to 9, of another five speakers were used to test the system. All the methods and algorithms used in this research were implemented using the features of Turbo C and C++ languages. From our investigation it is seen that the developed system can successfully encode and analyze the mfcc features of the speech signal to recognition. The developed system achieved recognition rate about 96.332% for known speakers (i.e., speaker dependent) and 92% for unknown speakers (i.e., speaker independent).
International Journal of Information Sciences and Techniques, 2012
A back projection method is used to generate a two-dimensional image from one-dimensional project... more A back projection method is used to generate a two-dimensional image from one-dimensional projections. As a back projection method, Inverse Radon Transformation is applied on the calculated conductance and conductivity to reconstruct two dimensional images. These images are compared to the target image. In the time of image reconstruction, different filters are used and these images are compared with each other and target image.
AbstractElectrical Impedance Tomography (EIT) is the technique to visualize spatial distribution... more AbstractElectrical Impedance Tomography (EIT) is the technique to visualize spatial distribution of Electrical resistivity (or conductivity) inside the object, such as human body. Unlike MRI and CT, EIT uses diffusion of current to deduce conductivity distribution. ...
Journal of Biomedical Informatics, 2019
This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
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Papers by Md. Ali Hossain