185 couples),and its association with depressive symp-toms using the Actor-Partner Interdependenc... more 185 couples),and its association with depressive symp-toms using the Actor-Partner InterdependenceModel. Diabetes-related distress reported byboth patients and spouses was associated witheach partner’s own depressive symptoms (actoreffects)butgenerallywasnotassociatedwiththeother’s depressive symptoms (partner effects).Moreover,diabetesdistresswasassociatedwith
Introduction With advances in information and communication technology, it is not possible to avo... more Introduction With advances in information and communication technology, it is not possible to avoid the impact of technology on mathematical problem solving. Among those technologies, there has been a steady increase in interest in using hand-held technologies, in particular graphing calculators, by mathematics educators and curriculum developers and teachers (Kissane, 2000). Using graphing calculators in learning mathematics will allow students to explore and model mathematical problems and create multiple representations of mathematical problems. Technology that supports multiple representations can increase students’ use of visualization in problem solving and enhance understanding (Center for Technology in Learning, 2007).
Visual Representations of Puerto Rico in Destination Marketing Materials. (August 2011) Mary Ann ... more Visual Representations of Puerto Rico in Destination Marketing Materials. (August 2011) Mary Ann Dávila Rodríguez, B.A., Humanities, Universidad de Puerto Rico, Carolina Chair of Advisory Committee: Dr. Ulrike Gretzel In the last thirty years, a large number of studies have researched the destination image that visitors, travel industry representatives, students, and general consumers have of tourist destinations. However, few studies have analyzed the perceptions that local residents have of their own countries as tourist destinations. Local residents can provide valuable information about their countries as tourism destinations and can help tourism marketers determine how to represent local culture in more authentic and sustainable ways. Local residents can also provide valuable information about how to improve tourism development based on their experiences living in the area. Residents can further provide information and services to visitors and are themselves an integral part of...
The following is from the final vows a sister makes when she enters the monastery of St. Hildegar... more The following is from the final vows a sister makes when she enters the monastery of St. Hildegard:(1)The CallingThe deacon says: Sister, the Lord calls you to follow him.Sister replies: Lord, you have called me; here I am.The bishop asks: Sister, what do you ask of God and of his holy Church?Sister answers: I ask for perseverance in following Christ my bridegroom in this monastic community all the days of my life.All respond: Thanks be to God.Christian monasticism is one of the oldest continuous western religious traditions. Monasticism defines the cultures of people who live celibate lives, apart from the world, in religious communities that are bound by vows of obedience to the rules that govern their communities. Christianity has produced many, diverse monastic groups dating from the middle of the third century A.D., primarily in Egypt, the birthplace of Christian monasticism. In the fourth and fifth centuries monastic rules were carried throughout Christendom, and experiments in monastic living became widespread. What was to become the Benedictine order, to which the monastery of St. Hildegard belongs, was founded in Italy around A.D. 525 by a group of monks under the direction of Benedict of Nursia, the author of the Rule of Benedict. This rule is the guide for monastic living by which all Benedictines still profess today.In spite of this cultural distinction, monasticism has long been neglected by anthropologists. The largest body of literature produced on religious vocation in the Uniited States has been written by members of the religious communities themselves. One may question the underlying motives and objectivity of members of a community doing a self-study. However, given the volume of material produced in the last thirty years, the orientation of the different orders involved, and the educational background and social science training of the authors, it is reasonable to take a serious look at this body of information and to search out the common themes and conclusions presented.Among the documents produced by Vatican II was a letter to religious orders instructing them to take a close look at their individual orders and to reform them in areas that were in need of reformation.(2) Across congregations, the sisters in the United States took this mandate from the Vatican quite seriously and began one of the most dramatic change in the history of Catholic religious women's orders. They were now empowered to look at their communities and decide what their mission would be and the methods they would employ to achieve it. During the process of this change many sisters would leave the orders and the ones who came would be not only of a new generation but of a new era.The decision that a Catholic woman makes to enter and to remain in a monastery is a topic which should be of interest to anthropologists. The thesis of my current research is that women who become nuns do so because of a sense of personal calling to love and serve God, contrary to the argument of many anthropologists that the decision is a utilitarian one motivated by political and economic conditions. The findings from this research confirm my thesis.In addition, and with farther reaching implications, however, the findings indicate that, in one aspect, the answer to this question remains constant over time. Over the course of their lives the desire to serve and love God did not change nor did the need to express it through community living. What the findings demonstrate, however, is a complete paradigm shift from an emphasis on a solitary relationship with God to a community orientation in the decision to become a nun. The orientation has changed to place primary emphasis away from a nun's solitary relationship with God and towards community relationships that nurture one's love of God.As one looks at Benedictine monasteries and the literature being produced by monastics, it is apparent that the widespread, steady decline in vocations is a serious and potentially terminal condition. …
Aims: The Early Assessment of Programs and Policies to Prevent Childhood Obesity project identifi... more Aims: The Early Assessment of Programs and Policies to Prevent Childhood Obesity project identified environmental and policy initiatives addressing childhood obesity. Methods: The systematic screening and assessment method, which includes an evaluability assessment, or an on-site pre-evaluation, was utilized to identify environmental and policy after-school and child-care initiatives. This method utilizes semi-structured face-to-face interviews to gather information about an initiative with the purpose of assessing readiness for an outcomes-focused evaluation. This paper synthesizes key findings from these evaluability assessments, qualitatively describes common characteristics of potentially promising initiatives, and identifies initiatives ready for an outcomes-focused evaluation. Results: Many initiatives were successful at leveraging resources and targeting children from economically disadvantaged groups; however, less than half were able to implement established nutrition or physical activity guidelines. Eight of 21 initiatives were deemed ready for an outcomes-focused evaluation. Conclusions: The insights gleaned from the evaluability assessments may inform other after-school and child-care initiatives. In addition, conducting outcomes-focused evaluations on the initiatives deemed ready will help build the evidence base for addressing childhood obesity in after-school and child-care programs.
A typical method of failure for ductile materials is spallation damage, which is caused by the nu... more A typical method of failure for ductile materials is spallation damage, which is caused by the nucleation, growth and coalescence of voids due to the presence of high tensile stress in the material. Spallation damage models, such as TEPLA, are currently implemented in hydrodynamic computer codes used at Los Alamos National Laboratory (LANL). Parameters for such constitutive models are derived from data sets obtained primarily from gas gun and shock-driven experiments, which are designed to allow onedimensional analysis of the evolution of the failure characteristics. However, in a non-planar geometry, advanced failure models predict failure to be a multi-dimensional process. Additionally, a limited amount of data exists for the process of void nucleation, growth and coalescence. Another lightly researched area is the state of the material in the event that the spallation layer is recollected and voids are closed. The experiments described here are being conducted as part of a Campaign-l effort to provide data addressing these issues. The Russian Damage Experimental Series is designed to provide fundamental non-planar (cylindrical) spallation damage data, including early time processes (void nucleation, growth and coalescence) and late time processes (recollection of the spallation layer). Previous experiments produced data addressing some of the early time processes. This presentation will be provided to LANL and VNIIEF colleagues as a means of assessing the status of Task Order #24 at the current time.
Women with high-normal or high blood pressure, as well as those whose blood pressure climbs to th... more Women with high-normal or high blood pressure, as well as those whose blood pressure climbs to those levels over time, are at substantially increased risk of developing type 2 diabetes. Their risk is elevated even if they are not overweight and have no other ...
Energy Efficiency in Communications and Networks, 2012
sampling method can solve the two SFOs problem in the two-branch STBC-OFDM based CTs. Simulations... more sampling method can solve the two SFOs problem in the two-branch STBC-OFDM based CTs. Simulations in the Section 4 will show that this low-cost scheme outperforms the ideal STBC system with no SFOs, and is robust to the mean SFO estimation error. In Section 5, the energy efficiency problem of the proposed schemes is analyzed. The chapter is summarized in Section 6.
Antibody-drug conjugates (ADCs), potent cytotoxic drugs linked to antibodies via specialized chem... more Antibody-drug conjugates (ADCs), potent cytotoxic drugs linked to antibodies via specialized chemical linkers, provide a means to increase the effectiveness of chemotherapy by targeting the drug to neoplastic cells while reducing side effects. Our research has focused on ADCs that contain the maytansinoid DM1, monomethylauristatin E (MMAE), or monomethylauristatin F (MMAF), all of which are potent inhibitors of microtubule polymerization. These drugs are attached to the antibody via several different linker formats (Table 1). Table 1 Linker-drug Linker Mechanism Linked via Drug Cell Permeable PAB-vc-MC-MMAE Cleavage of peptide bond Cysteine Yes MC-MMAF Uncleavable Cysteine No SPP-DM1 Reduction of disulfide bond Lysine Yes MCC-DM1 Uncleavable Lysine Yes We identified seven cell surface proteins expressed in non-Hodgkin lymphoma (NHL) with limited expression patterns in normal tissue (CD19, CD20, CD21, CD22, CD72, CD79, and CD180), as potential therapeutic targets for ADCs. ADCs direc...
185 couples),and its association with depressive symp-toms using the Actor-Partner Interdependenc... more 185 couples),and its association with depressive symp-toms using the Actor-Partner InterdependenceModel. Diabetes-related distress reported byboth patients and spouses was associated witheach partner’s own depressive symptoms (actoreffects)butgenerallywasnotassociatedwiththeother’s depressive symptoms (partner effects).Moreover,diabetesdistresswasassociatedwith
Introduction With advances in information and communication technology, it is not possible to avo... more Introduction With advances in information and communication technology, it is not possible to avoid the impact of technology on mathematical problem solving. Among those technologies, there has been a steady increase in interest in using hand-held technologies, in particular graphing calculators, by mathematics educators and curriculum developers and teachers (Kissane, 2000). Using graphing calculators in learning mathematics will allow students to explore and model mathematical problems and create multiple representations of mathematical problems. Technology that supports multiple representations can increase students’ use of visualization in problem solving and enhance understanding (Center for Technology in Learning, 2007).
Visual Representations of Puerto Rico in Destination Marketing Materials. (August 2011) Mary Ann ... more Visual Representations of Puerto Rico in Destination Marketing Materials. (August 2011) Mary Ann Dávila Rodríguez, B.A., Humanities, Universidad de Puerto Rico, Carolina Chair of Advisory Committee: Dr. Ulrike Gretzel In the last thirty years, a large number of studies have researched the destination image that visitors, travel industry representatives, students, and general consumers have of tourist destinations. However, few studies have analyzed the perceptions that local residents have of their own countries as tourist destinations. Local residents can provide valuable information about their countries as tourism destinations and can help tourism marketers determine how to represent local culture in more authentic and sustainable ways. Local residents can also provide valuable information about how to improve tourism development based on their experiences living in the area. Residents can further provide information and services to visitors and are themselves an integral part of...
The following is from the final vows a sister makes when she enters the monastery of St. Hildegar... more The following is from the final vows a sister makes when she enters the monastery of St. Hildegard:(1)The CallingThe deacon says: Sister, the Lord calls you to follow him.Sister replies: Lord, you have called me; here I am.The bishop asks: Sister, what do you ask of God and of his holy Church?Sister answers: I ask for perseverance in following Christ my bridegroom in this monastic community all the days of my life.All respond: Thanks be to God.Christian monasticism is one of the oldest continuous western religious traditions. Monasticism defines the cultures of people who live celibate lives, apart from the world, in religious communities that are bound by vows of obedience to the rules that govern their communities. Christianity has produced many, diverse monastic groups dating from the middle of the third century A.D., primarily in Egypt, the birthplace of Christian monasticism. In the fourth and fifth centuries monastic rules were carried throughout Christendom, and experiments in monastic living became widespread. What was to become the Benedictine order, to which the monastery of St. Hildegard belongs, was founded in Italy around A.D. 525 by a group of monks under the direction of Benedict of Nursia, the author of the Rule of Benedict. This rule is the guide for monastic living by which all Benedictines still profess today.In spite of this cultural distinction, monasticism has long been neglected by anthropologists. The largest body of literature produced on religious vocation in the Uniited States has been written by members of the religious communities themselves. One may question the underlying motives and objectivity of members of a community doing a self-study. However, given the volume of material produced in the last thirty years, the orientation of the different orders involved, and the educational background and social science training of the authors, it is reasonable to take a serious look at this body of information and to search out the common themes and conclusions presented.Among the documents produced by Vatican II was a letter to religious orders instructing them to take a close look at their individual orders and to reform them in areas that were in need of reformation.(2) Across congregations, the sisters in the United States took this mandate from the Vatican quite seriously and began one of the most dramatic change in the history of Catholic religious women's orders. They were now empowered to look at their communities and decide what their mission would be and the methods they would employ to achieve it. During the process of this change many sisters would leave the orders and the ones who came would be not only of a new generation but of a new era.The decision that a Catholic woman makes to enter and to remain in a monastery is a topic which should be of interest to anthropologists. The thesis of my current research is that women who become nuns do so because of a sense of personal calling to love and serve God, contrary to the argument of many anthropologists that the decision is a utilitarian one motivated by political and economic conditions. The findings from this research confirm my thesis.In addition, and with farther reaching implications, however, the findings indicate that, in one aspect, the answer to this question remains constant over time. Over the course of their lives the desire to serve and love God did not change nor did the need to express it through community living. What the findings demonstrate, however, is a complete paradigm shift from an emphasis on a solitary relationship with God to a community orientation in the decision to become a nun. The orientation has changed to place primary emphasis away from a nun's solitary relationship with God and towards community relationships that nurture one's love of God.As one looks at Benedictine monasteries and the literature being produced by monastics, it is apparent that the widespread, steady decline in vocations is a serious and potentially terminal condition. …
Aims: The Early Assessment of Programs and Policies to Prevent Childhood Obesity project identifi... more Aims: The Early Assessment of Programs and Policies to Prevent Childhood Obesity project identified environmental and policy initiatives addressing childhood obesity. Methods: The systematic screening and assessment method, which includes an evaluability assessment, or an on-site pre-evaluation, was utilized to identify environmental and policy after-school and child-care initiatives. This method utilizes semi-structured face-to-face interviews to gather information about an initiative with the purpose of assessing readiness for an outcomes-focused evaluation. This paper synthesizes key findings from these evaluability assessments, qualitatively describes common characteristics of potentially promising initiatives, and identifies initiatives ready for an outcomes-focused evaluation. Results: Many initiatives were successful at leveraging resources and targeting children from economically disadvantaged groups; however, less than half were able to implement established nutrition or physical activity guidelines. Eight of 21 initiatives were deemed ready for an outcomes-focused evaluation. Conclusions: The insights gleaned from the evaluability assessments may inform other after-school and child-care initiatives. In addition, conducting outcomes-focused evaluations on the initiatives deemed ready will help build the evidence base for addressing childhood obesity in after-school and child-care programs.
A typical method of failure for ductile materials is spallation damage, which is caused by the nu... more A typical method of failure for ductile materials is spallation damage, which is caused by the nucleation, growth and coalescence of voids due to the presence of high tensile stress in the material. Spallation damage models, such as TEPLA, are currently implemented in hydrodynamic computer codes used at Los Alamos National Laboratory (LANL). Parameters for such constitutive models are derived from data sets obtained primarily from gas gun and shock-driven experiments, which are designed to allow onedimensional analysis of the evolution of the failure characteristics. However, in a non-planar geometry, advanced failure models predict failure to be a multi-dimensional process. Additionally, a limited amount of data exists for the process of void nucleation, growth and coalescence. Another lightly researched area is the state of the material in the event that the spallation layer is recollected and voids are closed. The experiments described here are being conducted as part of a Campaign-l effort to provide data addressing these issues. The Russian Damage Experimental Series is designed to provide fundamental non-planar (cylindrical) spallation damage data, including early time processes (void nucleation, growth and coalescence) and late time processes (recollection of the spallation layer). Previous experiments produced data addressing some of the early time processes. This presentation will be provided to LANL and VNIIEF colleagues as a means of assessing the status of Task Order #24 at the current time.
Women with high-normal or high blood pressure, as well as those whose blood pressure climbs to th... more Women with high-normal or high blood pressure, as well as those whose blood pressure climbs to those levels over time, are at substantially increased risk of developing type 2 diabetes. Their risk is elevated even if they are not overweight and have no other ...
Energy Efficiency in Communications and Networks, 2012
sampling method can solve the two SFOs problem in the two-branch STBC-OFDM based CTs. Simulations... more sampling method can solve the two SFOs problem in the two-branch STBC-OFDM based CTs. Simulations in the Section 4 will show that this low-cost scheme outperforms the ideal STBC system with no SFOs, and is robust to the mean SFO estimation error. In Section 5, the energy efficiency problem of the proposed schemes is analyzed. The chapter is summarized in Section 6.
Antibody-drug conjugates (ADCs), potent cytotoxic drugs linked to antibodies via specialized chem... more Antibody-drug conjugates (ADCs), potent cytotoxic drugs linked to antibodies via specialized chemical linkers, provide a means to increase the effectiveness of chemotherapy by targeting the drug to neoplastic cells while reducing side effects. Our research has focused on ADCs that contain the maytansinoid DM1, monomethylauristatin E (MMAE), or monomethylauristatin F (MMAF), all of which are potent inhibitors of microtubule polymerization. These drugs are attached to the antibody via several different linker formats (Table 1). Table 1 Linker-drug Linker Mechanism Linked via Drug Cell Permeable PAB-vc-MC-MMAE Cleavage of peptide bond Cysteine Yes MC-MMAF Uncleavable Cysteine No SPP-DM1 Reduction of disulfide bond Lysine Yes MCC-DM1 Uncleavable Lysine Yes We identified seven cell surface proteins expressed in non-Hodgkin lymphoma (NHL) with limited expression patterns in normal tissue (CD19, CD20, CD21, CD22, CD72, CD79, and CD180), as potential therapeutic targets for ADCs. ADCs direc...
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