Papers by Marta Rodríguez-belvís
Archivos De Bronconeumologia, Sep 1, 2014
Background: Respiratory tract infections are one of the most frequent problems in pediatric clini... more Background: Respiratory tract infections are one of the most frequent problems in pediatric clinics and generate an elevated prescription of antibiotics. The aim of this study was to find out the standard of care practice about antibiotic use in these infections in a pediatric emergency department and to evaluate compliance with clinical guidelines. Methods: A pediatric emergency department database was reviewed from July 2005 to October 2007 under the category "respiratory infection", including variables such as age, antibiotic prescription and compliance with current clinical recommendations. Results: Out of the 23 114 reviewed reports, 32.7% (7567) were upper respiratory tract infections (URTI) (cold, acute otitis media [AOM], sinusitis and tonsillopharyngitis) or lower respiratory tract infections (LRTI) (laryngitis, bronchitis, bronchiolitis and pneumonia). Children under the age of 2 were the most represented age group. Amongst URTI, rhinopharyngitis was the most frequent infection, while bronchitis was the most frequent among LRTI. Antibiotic therapy (mainly amoxicillin) was prescribed in 30.8% of URTI (5.7% rhinopharyngitis, 96.5% AOM, and 36.7% tonsillopharyngitis) and in 12.4% of LRTI. Conclusions: The percentage of respiratory tract infections was similar to previous studies and the antibiotic prescriptions followed current guidelines, except for cases diagnosed with AOM. Prescription compliance and clinical course of the cases should be monitored.
Nutricion Hospitalaria, Oct 15, 2017
Proper nutrition during childhood is necessary to: allow adequate growth and development, achieve... more Proper nutrition during childhood is necessary to: allow adequate growth and development, achieve optimal physical and psychic performance, maintain and improve health and recover more easily in disease processes. The first months of life (the infant stage) are a stage in which many rapid changes take place (anthropometric, body composition, maturation of organs and systems...), which suppose a high demand from nutritional point of view, in the quantitative aspect and especially in the qualitative aspect. After infant stage, preschool children feeding is an opportunity to acquire healthy habits and introduce new foods, textures, flavors, colors, etc., which will favor the autonomy and development of the individual, as well as being essential to maintain growth and development. De lactante a niño. Alimentación en diferentes etapas From infant to child. Feeding in different stages
Nutricion Hospitalaria, Oct 15, 2017
Proper nutrition during childhood is necessary to: allow adequate growth and development, achieve... more Proper nutrition during childhood is necessary to: allow adequate growth and development, achieve optimal physical and psychic performance, maintain and improve health and recover more easily in disease processes. The first months of life (the infant stage) are a stage in which many rapid changes take place (anthropometric, body composition, maturation of organs and systems...), which suppose a high demand from nutritional point of view, in the quantitative aspect and especially in the qualitative aspect. After infant stage, preschool children feeding is an opportunity to acquire healthy habits and introduce new foods, textures, flavors, colors, etc., which will favor the autonomy and development of the individual, as well as being essential to maintain growth and development. De lactante a niño. Alimentación en diferentes etapas From infant to child. Feeding in different stages
Nutricion Hospitalaria, 2020
Journal of Crohn's and Colitis, May 1, 2021
was changed to 86 (84%) CD, 8 (8%) UC and 7 (7%) IBD-U. The two patients whose diagnosis was chan... more was changed to 86 (84%) CD, 8 (8%) UC and 7 (7%) IBD-U. The two patients whose diagnosis was changed from IBD-U to CD satisfied the items of Class 1, so the diagnosis was changed. All 7 patients whose diagnosis changed from UC to IBD-U did not satisfy all the items of Class 1, but most of the items 'Focal active colitis on histology in more than one biopsy' (6/7) and 'Focal enhanced gastritis on histology' (7/7) of class 3 criteria were satisfied, and the diagnosis has changed. Conclusion: As a result of applying the PIBD class criteria, there was no significant change in the diagnosis of CD, but the diagnosis of UC decreased by 73% and the diagnosis of IBD-U increased by 5 times. In this study group, the positive rates of items 'Fistulising disease', ''Thickened jejunal or ileal bowel loops on radiology or other evidence of significant small bowel inflammation on capsule endoscopy', 'Focal active colitis on histology in more than one biopsy' and 'Focal enhanced gastritis on histology' tended to be significantly higher than those of the previous study. So, Further validation and confirmation are needed.
Journal of Crohn's and Colitis, May 1, 2021
Conclusion: In older adults, steroid failure, the need for colectomy during the same admission an... more Conclusion: In older adults, steroid failure, the need for colectomy during the same admission and colectomy at 12 months is similar to a population <60 years of age. Mortality (at 3 and 12 months) is significantly higher.
Nutricion Hospitalaria, Sep 7, 2018
asistencia editorial. Cabe señalar que Baxter S.L. no participó en la preparación del documento n... more asistencia editorial. Cabe señalar que Baxter S.L. no participó en la preparación del documento ni la empresa influyó de ninguna manera en las conclusiones alcanzadas. Soporte nutricional y nutrición parenteral en el paciente oncológico: informe de consenso de un grupo de expertos Nutritional support and parenteral nutrition in the oncological patient: an expert group consensus report
European Journal of Pediatrics
The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus ... more The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly worldwide, seriously endangering human health. Although SARS‐CoV‐2 had a lower impact on paediatric population, children with COVID-19 have been reported as suffering from gastrointestinal (GI) symptoms at a higher rate than adults. The aim of this work was to evaluate faeces as a source of potential biomarkers of severity in the paediatric population, with an emphasis on intestinal microbiota and faecal immune mediators, trying to identify possible dysbiosis and immune intestinal dysfunction associated with the risk of hospitalization. This study involved 19 patients with COVID-19 under 24 months of age hospitalized during the pandemic at 6 different hospitals in Spain, and it included a comparable age-matched healthy control group (n = 18). Patients and controls were stratified according to their age in two groups: newborns or young infants (from 0 to ...
Journal of Crohn's and Colitis, 2021
Background To determine the nutritional status in patients with inflammatory bowel disease (IBD) ... more Background To determine the nutritional status in patients with inflammatory bowel disease (IBD) and its possible relationship with the activity of the disease. Methods A cross-sectional and descriptive study of paediatric patients with previously diagnosed or suspected IBD who underwent upper endoscopy (EGD) and colonoscopy, blood tests, stool analysis and MR Enterography (MRE), from October 2018 to February 2020. Results We recruited 21 patients and 12 of them were males (57%). A total of 12 patients had Crohn ́s disease (CD) (57%), 3 had ulcerative colitis (UC) (14%), 6 had IBD unclassified (IBDu) (28%). The age at the time of the evaluation was 14.2 ± 0.7 years and the progression time of the disease was 3.9 ± 0.6 years. A total of 16 patients showed clinical remission (76%), and 6 of them (28%) also had endoscopic and histological remission. Eight patients were receiving biological treatment (38%). Rotavirus, adenovirus, Clostridium difficile toxin analysis and stool culture we...
Nutrición Hospitalaria, 2019
Introduction Although the benefits of breastfeeding are clear and well documented, for both newbo... more Introduction Although the benefits of breastfeeding are clear and well documented, for both newborns and nursing mothers, breastfeeding rates worldwide are not optimal in many cases. There are multiple myths and errors related to breastfeeding: that certain foods cannot be consumed during breastfeeding, that, however, certain foods must be consumed to increase milk production, that composition of breast milk is not adequate in some cases, that breastfeeding is associated with more risk of suffering caries… Therefore, the objective of this article is to clarify the reality about these aspects of breastfeeding.
Background/Objectives: The paediatric reference range of fecal calprotectin (FC) has not been dec... more Background/Objectives: The paediatric reference range of fecal calprotectin (FC) has not been decisively established and previous studies show a wide within-age variability, suggesting that other factors like anthropometric data or type of feeding can influence FC. Our aims were to establish the normal levels of FC in healthy children grouped by age and analyze whether sex, gestational age, birth weight, type of delivery, type of feeding, or anthropometric data influence FC values. Methods: This multicentre, cross-sectional, and observational study enrolled healthy donors under 18 years of age who attended their Primary Health Care Centre for their routine Healthy Child Program visits. The exclusion criteria were: (i) immunodeficiency, (ii) autoimmune or (iii) gastrointestinal disease; (iv) medication usage; (v) gastrointestinal symptoms; or (vi) positive finding in the microbiological study. Results: We enrolled 395 subjects, mean age was 4.2 years (range 3 days to 16.9 years), and 204 were male. The median FC was 77.0 mcg/g (interquartile range 246). A negative correlation between age and FC was observed (Spearman's rho = −0.603, P<0.01), and none of the other factors analyzed were found to influence FC levels. Conclusions: Normal FC values in healthy children (particularly in infants) are higher than those considered to be altered in adults and show a negative correlation with age. It is necessary to reconsider the upper limits of FC levels for paediatric patients according to age, with further studies required to determine other factors that influence FC during infancy.
Nutricion Hospitalaria, 2019
Nutricion Hospitalaria, 2017
Archivos de Bronconeumología, 2014
Background: Respiratory tract infections are one of the most frequent problems in pediatric clini... more Background: Respiratory tract infections are one of the most frequent problems in pediatric clinics and generate an elevated prescription of antibiotics. The aim of this study was to find out the standard of care practice about antibiotic use in these infections in a pediatric emergency department and to evaluate compliance with clinical guidelines. Methods: A pediatric emergency department database was reviewed from July 2005 to October 2007 under the category "respiratory infection", including variables such as age, antibiotic prescription and compliance with current clinical recommendations. Results: Out of the 23 114 reviewed reports, 32.7% (7567) were upper respiratory tract infections (URTI) (cold, acute otitis media [AOM], sinusitis and tonsillopharyngitis) or lower respiratory tract infections (LRTI) (laryngitis, bronchitis, bronchiolitis and pneumonia). Children under the age of 2 were the most represented age group. Amongst URTI, rhinopharyngitis was the most frequent infection, while bronchitis was the most frequent among LRTI. Antibiotic therapy (mainly amoxicillin) was prescribed in 30.8% of URTI (5.7% rhinopharyngitis, 96.5% AOM, and 36.7% tonsillopharyngitis) and in 12.4% of LRTI. Conclusions: The percentage of respiratory tract infections was similar to previous studies and the antibiotic prescriptions followed current guidelines, except for cases diagnosed with AOM. Prescription compliance and clinical course of the cases should be monitored.
Anales de Pediatría, 2014
Journal of Clinical Medicine
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Journal of Crohn's and Colitis
Background In the recent decades, the incidence of Clostridioides difficile (Cd) infection in chi... more Background In the recent decades, the incidence of Clostridioides difficile (Cd) infection in children with inflammatory bowel disease (IBD) has increased, possibly due to underlying dysbiosis. The main objective of this study is to compare the prevalence of this infection in patients with IBD and without it, as well as secondarily to describe risk factors for Cd and its impact on the evolution of IBD. Methods Unicentric, observational and retrospective study of paediatric patients (<18 years old) undergoing Cd screening at the Hospital Infantil Universitario Niño Jesús in the last 5 years. Patients with IBD were those who met the Porto criteria. Statistical analysis was performed using SPSS. Results 3,360 paediatric patients were included. Of the 150 patients whose screening was requested by the Digestive Section, 87 had IBD. There were no statistically significant differences in the prevalence of infection in patients with IBD compared to other patients (p=0,061). According to ...
Gastroenterología y Hepatología
Journal of Crohn's and Colitis
Background Inflammatory bowel disease causes increased granulocyte and monocyte activation. Leuko... more Background Inflammatory bowel disease causes increased granulocyte and monocyte activation. Leukocytapheresis (LCA) is a safe technique that has shown efficacy in ulcerative colitis wich replaces activated leukocytes decreasing the cytokines involved in inflammatory response. The objective of this report is to describe the main characteristics of patients in whom LCA was made and evaluate the response to different types of LCA. Methods A descriptive and retrospective study that analyses clinical and analytical data of patients diagnosed with IBD who underwent LCA a cause of refractory to conventional treatment, in a tertiary paediatric hospital between 2006 and 2022. The following variables were studied: Demographic data, treatments before and during LCA, reason for the onset of LCA, clinical and analytical situation, characteristics of the sessions, beneficial and side effects. Results 10 patients (3 women and 7 men) diagnosed with ulcerative colitis (E4S1) were included. The mean ...
Journal of Pediatric Gastroenterology & Nutrition
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Papers by Marta Rodríguez-belvís