Papers by Mahbubur Rahman
The Journal of Clinical Endocrinology & Metabolism, 2008
Introduction: Depot medroxyprogesterone acetate (DMPA; Depo-Provera, Tadworth, UK) contraception ... more Introduction: Depot medroxyprogesterone acetate (DMPA; Depo-Provera, Tadworth, UK) contraception is used by more than 9 million women worldwide and has a high usage among teenagers in the United Kingdom and the United States. Previous studies have found that DMPA use is associated with a bone density deficit. Objectives: This case-control matched study aims to eliminate potential confounding factors, identify whether the effect of DMPA on the skeleton is age specific, and determine the effects of DMPA on hormones and bone turnover. Design/Participants: We measured bone density, bone turnover, and hormones in individually matched case-control pairs of women: 50 pairs aged 18-25 yr and 50 pairs aged 35-45 yr. Results: DMPA use was associated with a 5% bone density deficit at the lumbar spine and hip in women who started DMPA use before age 20 yr but not after age 34 yr. Bone turnover was increased in DMPA users in both age groups. DMPA users had lower estradiol and higher IGF-I than controls, and younger DMPA users had higher dehydroepiandrosterone sulfate than controls. In a multiple regression model, estradiol and IGF-I were associated with bone turnover, but addition of DMPA to the model made the association with estradiol nonsignificant. Conclusions: DMPA use is associated with a bone density deficit at the spine and hip when used before peak bone mass. DMPA acts on the skeleton mainly through estrogen deficiency.
Journal of women's health (2002), 2015
Hyperpalatable foods (i.e., high in salt, sugar, or fat) have been shown to have addictive proper... more Hyperpalatable foods (i.e., high in salt, sugar, or fat) have been shown to have addictive properties that may contribute to overeating. Prior studies conducted on food addiction behaviors are mostly based on white and middle-aged women. Data are not available, however, on reproductive-aged women from other races/ethnicities or low-income women. The purpose of this study was to examine the prevalence and correlates of food addiction among multiethnic women of low socioeconomic status. We conducted a cross-sectional survey of health behaviors, including food addiction according to the Yale Food Addiction Scale (YFAS) between July 2010 and February 2011 among 18- to 40-year-old low-income women attending reproductive-health clinics (N = 1,067). Overall, 2.8% of women surveyed met the diagnosis of food addiction. The prevalence of food addiction did not differ by age group, race/ethnicity, education, income, or body mass index categories, tobacco and alcohol use, or physical activity. ...
Osteoporosis International, 2009
Racial/ethnic differences were observed in age at peak bone density and their correlates, with wh... more Racial/ethnic differences were observed in age at peak bone density and their correlates, with whites peaking at least 5 years earlier at the femoral neck than black and Hispanic women. Race-specific standards generated in this study could be useful when interpreting bone densitometry data in young women. Introduction The influence of race/ethnicity on bone measurements has not been widely examined. This study identifies age and amount of bone accumulated at peak density and their correlates by race/ethnicity. Methods Bone mineral content (BMC) and bone mineral density (BMD) of the spine and femoral neck were measured by dual X-ray absorptiometry in 708 white, black, and Hispanic reproductive-aged women. Racespecific nonlinear models were used to describe the relationship between age and bone measurements, after adjusting for body weight and height. Log-transformed bone measurements were used to determine predictors based on multiple linear regression. Results Predictors, which were race and site specific, included age, age at menarche, body weight, height, months of depot medroxyprogesterone acetate use, weight-bearing exercise, and alcohol use. Women of all races gained BMC and BMD at the spine up to 30-33 years of age. BMC and BMD of the femoral neck peaked among white women earlier (≤16 years) than among blacks (BMC 22 years; BMD 21 years) and Hispanics (BMC 29 years; BMD 20 years). Conclusion Age at peak bone mass and its correlates differ by race/ethnicity. Race-specific standards generated in this study could be useful when interpreting bone densitometry data in young women.
International journal of …, 2000
Methods We conducted a hospital-based case-control study in Rajshahi, Bangladesh, to examine the ... more Methods We conducted a hospital-based case-control study in Rajshahi, Bangladesh, to examine the relationship of type of smoking materials (cigarette versus bidi) with TAO on 103 pairs of cases and controls matched by age and sex during the period 1995 to 1996. The inclusion ...
Materials
A high number of technical elastomer products contain plasticizers for tailoring material propert... more A high number of technical elastomer products contain plasticizers for tailoring material properties. Some additives used as plasticizers pose a health risk or have inadequate material properties. Therefore, research is going on in this field to find sustainable alternatives for conventional plasticizers. In this paper, two modified bio-based plasticizers (epoxidized esters of glycerol formal from soybean and canola oil) are of main interest. The study aimed to determine the influence of these sustainable plasticizers on the properties of acrylonitrile–butadiene rubber (NBR). For comparison, the influence of conventional plasticizers, e.g., treated distillate aromatic extract (TDAE) and Mesamoll® were additionally investigated. Two types of NBR with different ratios of monomers formed the polymeric basis of the prepared elastomers. The variation of the monomer ratio results in different polarities, and therefore, compatibility between the NBR and plasticizers should be influenced. T...
Journal of Bangladesh College of Physicians and Surgeons
Loop gastro-Jejunostomy and Roux-en-Y gastro- Jejunostomy, the commonest reconstructions in gastr... more Loop gastro-Jejunostomy and Roux-en-Y gastro- Jejunostomy, the commonest reconstructions in gastric surgery, are significantly associated with alkaline reflux gastritis and Roux stasis syndrome (RSS) respectively. The Modified Uncut Roux-en-Y (MUREY) technique could be an effective technique in preventing both the conditions. This prospective observational study was designed to evaluate the effectiveness of Modified UREY reconstruction to prevent RSS and Alkaline reflux gastro-esophagitis while avoiding “Staple- line dehiscence”. A total of 47 patients of gastric outlet obstruction, both benign and malignant, undergoing Modified Uncut Roux-en-Y reconstruction with/ without Gastrectomy at BMCH over the span of July 2014 to July 2016, were incorporated in this study. Patients were followed up from the immediate post-operative periods till discharge and postoperatively for 2 months. There was no incidence of bile reflux or bilious vomiting in the follow-up period. There were two (4.3%)...
International journal of hygiene and environmental health, Jan 8, 2018
Environmental enteropathy (EE) is characterised by subclinical inflammation and hyperpermeability... more Environmental enteropathy (EE) is characterised by subclinical inflammation and hyperpermeability of the small intestine, hypothesised to be caused by recurrent ingestion of faecal bacteria. It has been suggested that EE may be a contributor to malnutrition and growth delays seen in children living in unsanitary conditions. We measured putative faecal EE markers myeloperoxidase (MPO) (ng/mL) and alpha-1-antitrypsin (AAT) (mg/g) in stool samples collected from 133 children aged 1-5 years in 16 communities enrolled in the WASH for WORMS randomised controlled trial in Timor-Leste. Samples were collected two years after a community-wide water, sanitation and hygiene (WASH) intervention that was integrated with regular deworming. Mixed effects multivariable linear regression models were used to examine the impact of the study intervention and of various WASH and infection-related factors on EE biomarkers. Children who lived in communities that received both the WASH intervention and dewo...
Zeitschrift fur Naturforschung. C, Journal of biosciences, Jan 25, 2018
Plant growth-promoting bacteria that are also capable of suppressing plant pathogenic fungi play ... more Plant growth-promoting bacteria that are also capable of suppressing plant pathogenic fungi play an important role in sustainable agriculture. There is a critical need for conducting research to discover, characterize and evaluate the efficacy of new strains of such bacteria in controlling highly aggressive plant pathogens. In this study, we isolated endophytic bacteria from medicinal plants of Bangladesh and evaluated their antagonistic capacity against an important phytopathogenic fungus Sclerotinia sclerotiorum. Growth-promoting effects of those isolates on cucumber and rice seedlings were also assessed. Among 16 morphologically distinct isolates, BDR-2, BRtL-2 and BCL-1 significantly inhibited the growth of S. sclerotiorum through induction of characteristic morphological alterations in hyphae and reduction of mycelial dry weight. When cucumber and rice seeds were treated with these endophytic bacteria, seven isolates (BCL-1, BDL-1, BRtL-2, BRtL-3, BDR-1, BDR-2 and BBoS-1) enhan...
American journal of epidemiology, Jan 27, 2018
Water, sanitation, and handwashing interventions may confer spillover effects on neighbors of int... more Water, sanitation, and handwashing interventions may confer spillover effects on neighbors of intervention recipients by interrupting pathogen transmission. We measured geographically local spillovers in WASH Benefits, a cluster-randomized trial in rural Bangladesh, by comparing outcomes among neighbors of intervention vs. control participants. WASH Benefits randomly allocated geographically-defined clusters to a compound-level intervention (chlorinated drinking water, upgraded sanitation, and handwashing promotion) or control. From January to August 2015, in 180 clusters, we enrolled 1,799 neighboring children age-matched to trial participants that would have been eligible for WASH Benefits had they been conceived slightly earlier or later. After 28 months of intervention, we quantified fecal indicator bacteria in toy rinse and drinking water samples, measured soil-transmitted helminth infections, and recorded caregiver-reported diarrhea and respiratory illness. Neighbors' char...
PloS one, 2018
Young children frequently defecate in the living environment in low-income countries. Unsafe chil... more Young children frequently defecate in the living environment in low-income countries. Unsafe child feces disposal has been associated with risk of diarrhea. Additionally, reported practices can underestimate socially undesirable unhygienic behaviors. This analysis aimed to assess (1) the sensitivity of reported child feces disposal practices as an indicator for observed presence of human feces in the domestic environment, (2) household characteristics associated with reported unsafe feces disposal and (3) whether unsafe feces disposal is associated with fly presence and diarrhea among children <3 years. We recorded caregiver-reported feces disposal practices for children <3 years; unsafe disposal was defined as feces put/rinsed into a drain, ditch, bush or garbage heap or left on the ground and safe disposal as feces put/rinsed into latrine or specific pit or buried. We conducted spot checks for human feces, counted flies in the compound and recorded caregiver-reported child d...
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Jan 13, 2018
Enteric protozoan infections are associated with morbidity and mortality worldwide. We evaluated ... more Enteric protozoan infections are associated with morbidity and mortality worldwide. We evaluated effects of individual and combined water, sanitation, handwashing (WSH), and nutritional interventions on protozoan infections in children. We randomized geographical clusters of pregnant women in rural Bangladesh into chlorinated drinking water, hygienic sanitation, handwashing, nutrition, combined WSH, combined nutrition plus WSH (N+WSH), or control arms. Participants were not masked. After ~2.5 years of intervention, we measured Giardia, Cryptosporidium, and Entamoeba histolytica prevalence and infection intensity by multiplex real-time PCR of child stool. Analysis was intention-to-treat. Between May 2012 and July 2013, we randomized 5551 pregnant women. At follow-up (May 2015-2016), among 4102 available women, we enrolled 6694 children into the protozoan assessment. We analyzed stool from 5933 children (aged ~31 months) for protozoan infections. Compared with 35.5% prevalence among c...
The American journal of tropical medicine and hygiene, Jan 12, 2018
We assessed the ability of sodium dichloroisocyanurate (NaDCC) to provide adequate chlorine resid... more We assessed the ability of sodium dichloroisocyanurate (NaDCC) to provide adequate chlorine residual when used to treat groundwater with variable iron concentration. We randomly selected 654 tube wells from nine subdistricts in central Bangladesh to measure groundwater iron concentration and corresponding residual-free chlorine after treating 10 L of groundwater with a 33-mg-NaDCC tablet. We assessed geographical variations of iron concentration using the Kruskal-Wallis test and examined the relationships between the iron concentrations and chlorine residual by quantile regression. We also assessed whether user-reported iron taste in water and staining of storage vessels can capture the presence of iron greater than 3 mg/L (the World Health Organization threshold). The median iron concentration among measured wells was 0.91 (interquartile range [IQR]: 0.36-2.01) mg/L and free residual chlorine was 1.3 (IQR: 0.6-1.7) mg/L. The groundwater iron content varied even within small geograp...
Computers and Electronics in Agriculture, 2015
ABSTRACT
Journal of health, population, and nutrition, 2001
Infections due to non-typhoid Salmonella, resistant to antibiotics, have recently emerged as an i... more Infections due to non-typhoid Salmonella, resistant to antibiotics, have recently emerged as an important health problem worldwide. Antibiotic resistance was studied by the disc-diffusion method among 3,876 (2.78%) non-typhoid Salmonella isolates cultured from 139,279 faecal samples in a diarrhoea treatment centre in Dhaka, Bangladesh, during 1989-1996. Of 499 salmonellae isolated in 1989, serogroup C (1.12%) was the most common, followed by Salmonella Typhi (0.72%) and serogroup B (0.71%). Isolation rate of serogroup B increased significantly to 2.18% (p < 0.01) in 1992 compared to 0.56% in 1991, 2.86% in 1995, and 2.48% in 1996. Serotyping of 194 serogroup B isolates revealed Salmonella Typhimurium (52%) and Salmonella Gloucester (45%) as predominant serotypes. Resistance to ampicillin (A), chloramphenicol (C), and trimethoprim-sulphamethoxazole (Sxt) (R type-ACSxt) increased to 89-100% during 1992-1996 from 20-28% during 1989-1991 (p < 0.01) among S. Typhimurium and S. Glou...
Molecular medicine (Cambridge, Mass.), 2000
Pregnancy is characterized by an inflammatory-like process and this may be exacerbated in preecla... more Pregnancy is characterized by an inflammatory-like process and this may be exacerbated in preeclampsia. The heme oxygenase (HO) enzymes generate carbon monoxide (CO) that induces blood vessel relaxation and biliverdin that acts as an endogenous antioxidant. We examined the expression and localization of HO-1 and HO-2 in normal and preeclamptic placenta using reverse transcription polymerase chain reaction (RT-PCR), RNase protection assay, immunoblotting and immunohistochemistry. In addition, the effect of HO activation on tumor necrosis factor-alpha (TNFalpha) induced placental damage and on feto-placental circulation was studied. We provide the first evidence for the role of HO as an endogenous placental factor involved with cytoprotection and placental blood vessel relaxation. HO-1 was significantly higher at term, compared with first trimester placentae indicating its role in placental vascular development and regulation. HO-1 predominantly localized in the extravascular connecti...
Advances in Integrated Design and Manufacturing in Mechanical Engineering, 2005
ABSTRACT Machine tools’ accuracy level is an important factor for producing accurate dimensions i... more ABSTRACT Machine tools’ accuracy level is an important factor for producing accurate dimensions in workpieces. To be sure about the suitable accuracy level, machine tool users use different kinds of measuring methods. There are two kind of measuring systems for machine tool measurements: static and dynamic measurement systems. There is a clear relationship between these measurements. In this work, a theoretical and practical relation has been established between static and dynamic measuring systems. These relations are important whenever machine tools are measured using different measuring devices to validate the measurement results. In this work the tool-tip trace obtained by one measuring system has been compared and simulated with the trace obtained by other methods. A number of systematic mathematical models have been developed and compared with the results obtained by alternative measuring methods.
Public Health, 2003
The objectives of this study were to describe the global profile of biomedical research productiv... more The objectives of this study were to describe the global profile of biomedical research productivity and to examine any improvement seen in it in the developing world during the period 1990-2000. Biomedical research articles published during 1990-2000 were accessed through the Medline database. The number of (journal) articles originating from each of the countries of the world, normalized to number of publications per million population (PPMP) per year, was elicited. In addition, the time trends of the number of publications in terms of each of the countries, continents, and economic groups were investigated. In terms of continents, North America had the highest number of biomedical PPMP per year (341.33); this was followed by Australia and Oceania (288.35), Europe (136.88), Asia (12.81), South America and Caribbean region (10.80), and Africa (3.50). In total, 52.7% of the countries showed a positive trend over time: 23.3% in South America, 28.9% in Africa, 40.0% in Australia and Oceania, 61.0% in Asia, 84.6% in Europe, and 100% in North America. All the continents except Africa showed a significantly positive trend. The share of the total number of publications went down for Africa (from 1.2 to 0.8%) and up slightly for Asia (from 14.3 to 15.6%) and South America (from 1.3 to 1.8%) during 2000 compared with 1990. The better the economic ranking of a country, the higher the number of biomedical PPMP. The total share of publications coming from low-income countries also fell, from 2% in 1990 to 1.7% in 2000. The imbalance between developed and developing countries in terms of biomedical research is significant. Pragmatic policies should be adopted by the World Bank, World Health Organization, other United Nations bodies, and respective governments to encourage biomedical research in the less-developed parts of the world.
Plant Tissue Culture and Biotechnology, 2010
Key words: Medicinal plant, Holarrhena antidysenterica, Wedelia chinensis, Woodfordia fruticos... more Key words: Medicinal plant, Holarrhena antidysenterica, Wedelia chinensis, Woodfordia fruticosa, In vitro cloning, Multiple shoot D.O.I. 10.3329/ptcb.v19i2.5443 Plant Tissue Cult. & Biotech. 19(2): 253-255, 2009 (December) - Short communication
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Papers by Mahbubur Rahman