Journal of the American College of Cardiology, 2016
Scar homogenization improves long-term ventricular arrhythmia-free survival compared with standar... more Scar homogenization improves long-term ventricular arrhythmia-free survival compared with standard limited-substrate ablation in patients with post-infarction ventricular tachycardia (VT). Whether such benefit extends to patients with nonischemic cardiomyopathy and scar-related VT is unclear. The aim of this study was to assess the long-term efficacy of an endoepicardial scar homogenization approach compared with standard ablation in this population. Consecutive patients with dilated nonischemic cardiomyopathy (n = 93), scar-related VTs, and evidence of low-voltage regions on the basis of pre-defined criteria on electroanatomic mapping (i.e., bipolar voltage <1.5 mV) underwent either standard VT ablation (group 1 [n = 57]) or endoepicardial ablation of all abnormal potentials within the electroanatomic scar (group 2 [n = 36]). Acute procedural success was defined as noninducibility of any VT at the end of the procedure; long-term success was defined as freedom from any ventricula...
Significant differences have been described between women and men regarding presentation, mechani... more Significant differences have been described between women and men regarding presentation, mechanism, and treatment outcome of certain arrhythmias. Previous studies of ventricular tachycardia (VT) ablation have not included sufficient women for meaningful comparison. To compare outcomes between women and men with structural heart disease undergoing VT ablation. Investigator-initiated, multicenter, observational study performed between 2002 and 2013, conducted by the International VT Ablation Center Collaborative Group, consisting of 12 high-volume ablation centers. Consecutive patients with structural heart disease undergoing VT ablation were studied. Structural heart disease was defined as left ventricular ejection fraction less than 55%, hypertrophic cardiomyopathy, or right ventricular cardiomyopathy, with scar confirmed during electroanatomic mapping. Catheter ablation. Ventricular tachycardia-free survival and transplant-free survival were compared between women and men. Cox pro...
OBJECTIVES The goal of this study was to evaluate the impact of hypertension on the outcome of at... more OBJECTIVES The goal of this study was to evaluate the impact of hypertension on the outcome of atrial fibrillation (AF) ablation.
Background: Limited data is available regarding the safety of performing electrophysiology study ... more Background: Limited data is available regarding the safety of performing electrophysiology study (EPS) on the same day of implantable cardioverter-defibrillator (ICD) implantation.
This paper presents the results of an ongoing study into the potential role of mobile or wireless... more This paper presents the results of an ongoing study into the potential role of mobile or wireless health applications for targeting the prevention of excessive gestational weight gain in pregnant lower-income American women. Informed by a qualitative study of pregnant women's experiences, we develop a set of design requirements for designing mobile health (mHealth) interventions related to healthy pregnancies. We identify a disconnection between physical activity and food tracking application design paradigms, and the reality of pregnant women's lives and capacities. We introduce the concept of an individualized pregnancy ecology, which provides an alternative paradigm for design of health and wellness management tools for lower-income pregnant women.
Journal of the American College of Cardiology, 2016
Scar homogenization improves long-term ventricular arrhythmia-free survival compared with standar... more Scar homogenization improves long-term ventricular arrhythmia-free survival compared with standard limited-substrate ablation in patients with post-infarction ventricular tachycardia (VT). Whether such benefit extends to patients with nonischemic cardiomyopathy and scar-related VT is unclear. The aim of this study was to assess the long-term efficacy of an endoepicardial scar homogenization approach compared with standard ablation in this population. Consecutive patients with dilated nonischemic cardiomyopathy (n = 93), scar-related VTs, and evidence of low-voltage regions on the basis of pre-defined criteria on electroanatomic mapping (i.e., bipolar voltage <1.5 mV) underwent either standard VT ablation (group 1 [n = 57]) or endoepicardial ablation of all abnormal potentials within the electroanatomic scar (group 2 [n = 36]). Acute procedural success was defined as noninducibility of any VT at the end of the procedure; long-term success was defined as freedom from any ventricula...
Significant differences have been described between women and men regarding presentation, mechani... more Significant differences have been described between women and men regarding presentation, mechanism, and treatment outcome of certain arrhythmias. Previous studies of ventricular tachycardia (VT) ablation have not included sufficient women for meaningful comparison. To compare outcomes between women and men with structural heart disease undergoing VT ablation. Investigator-initiated, multicenter, observational study performed between 2002 and 2013, conducted by the International VT Ablation Center Collaborative Group, consisting of 12 high-volume ablation centers. Consecutive patients with structural heart disease undergoing VT ablation were studied. Structural heart disease was defined as left ventricular ejection fraction less than 55%, hypertrophic cardiomyopathy, or right ventricular cardiomyopathy, with scar confirmed during electroanatomic mapping. Catheter ablation. Ventricular tachycardia-free survival and transplant-free survival were compared between women and men. Cox pro...
OBJECTIVES The goal of this study was to evaluate the impact of hypertension on the outcome of at... more OBJECTIVES The goal of this study was to evaluate the impact of hypertension on the outcome of atrial fibrillation (AF) ablation.
Background: Limited data is available regarding the safety of performing electrophysiology study ... more Background: Limited data is available regarding the safety of performing electrophysiology study (EPS) on the same day of implantable cardioverter-defibrillator (ICD) implantation.
This paper presents the results of an ongoing study into the potential role of mobile or wireless... more This paper presents the results of an ongoing study into the potential role of mobile or wireless health applications for targeting the prevention of excessive gestational weight gain in pregnant lower-income American women. Informed by a qualitative study of pregnant women's experiences, we develop a set of design requirements for designing mobile health (mHealth) interventions related to healthy pregnancies. We identify a disconnection between physical activity and food tracking application design paradigms, and the reality of pregnant women's lives and capacities. We introduce the concept of an individualized pregnancy ecology, which provides an alternative paradigm for design of health and wellness management tools for lower-income pregnant women.
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