Papers by Mozaffar Hosseininezhad
Iranian Journal of Neurosurgery, 2021
Background and Aim: Chronic low Back Pain (CLBP) is one of the most common musculoskeletal disord... more Background and Aim: Chronic low Back Pain (CLBP) is one of the most common musculoskeletal disorders with possible psychological consequences for the patients. This study aimed to review all evidence on the effectiveness of psychological interventions in improving the mental status of people with CLBP and providing recommendations for future therapeutic interventions. Methods and Materials/Patients: This systematic review was conducted on the articles published from January 2010 to December 2020. The keywords included “psychology”, “intervention”, “low back pain”, “chronic disease”, “quality of life”, “empowerment”, “psychotherapy”, “psychological interventions”, “clinical trials”, and “randomized clinical trials” in the indexing databases of Magiran, PubMed, Scopus, and Google Scholar. Of the total 1740 articles found, 14 articles were selected for review. Results: The results showed that Cognitive-Behavioral Therapy (CBT) and its combination therapies with mindfulness techniques p...
Background: Intracerebral hemorrhage (ICH) is the most fatal subtype of stroke. Despite limited e... more Background: Intracerebral hemorrhage (ICH) is the most fatal subtype of stroke. Despite limited effective therapy, there is no accepted clinical grading scale to predict in-hospital mortality, especially in developing nations. The purpose of this study was to assess the predictors of in-hospital mortality among a sample of Iranian patients with spontaneous ICH for use at the time of the first evaluation. Methods: This prospective study was carried from January 2010 to the end of January 2011. Demographic, clinical, and laboratory data of ICH patients were collected. Hematoma volume and perihematoma edema (PHE) were measured on brain computed tomography scan using ABC/2 formula. Logistic regression analysis was performed to determine independent variables contributing to in-hospital mortality. Results: Of a total 167 consecutive ICH patients, 98 patients met inclusion criteria. Mean ± standard deviation age of patients was 70.16 ± 12.52. After multivariate analysis, five variables re...
Journal of Advances in Medical and Biomedical Research, 2021
10.30699/jambs.29.136.286 Background & Objective: Both duloxetine (DLX) and transcutaneous electr... more 10.30699/jambs.29.136.286 Background & Objective: Both duloxetine (DLX) and transcutaneous electrical nerve stimulation (TENS) are recommended as safe and effective treatments for diabetic peripheral neuropathic pain. However, these methods have not been compared. This study aimed to compare the efficacy of treatment by DLX and TENS in diabetic neuropathy pain relief. Materials & Methods: This survey was performed on 60 eligible diabetic patients randomly divided into two groups of DLX (20, 40, and 60 mg/day for weeks 1, 2, and 3-12, respectively), and TENS (20 min,80 HZ, 50 Amp, 0.2 ms Square pulses 2-3 times sensory threshold). The participants were evaluated according to the numerical rating scale (NRS) after four and twelve weeks of treatment. Moreover, adverse drug reactions were documented during the study period. Results: Baseline demographic data had no significant difference between the two groups (P≥0.05). The average NRS scores were significantly lower in the DLX group in both measurement times. At the end of weeks four (P=0.01) and 12 (P=0.001), the trend of changes was significant from baseline to the third month (P=0.0001). No patient in the TENS group reported any side effects, while 18% did in the DLX group. Conclusion: We found that both DLX and TENS were effective and safe for the management of painful diabetic neuropathy. The DLX seemed to be better, compared to TENS. However, in some conditions, such as drug intolerance or contraindication for medications, TENS could be a proper intervention.
Journal of Guilan University of Medical Sciences, 2020
Background: Stroke is one of the most important causes of disability-adjusted life years lost. Lo... more Background: Stroke is one of the most important causes of disability-adjusted life years lost. Low socioeconomic status is associated with increased stroke-related morbidity and mortality. Objective: This study aimed to investigate in-hospital mortality rate caused by severe cases of ischemic and hemorrhagic stroke and its relationship with patients’ socioeconomic status. Materials and Methods: This comparative analytical study with a cross-sectional design was conducted from April 2018 to March 2019 on 384 patients diagnosed with severe stroke admitted to the neurology department of Poursina Hospital in Rasht, Iran, who were selected using a purposive sampling method. They completed a demographic checklist and the Socio-Economic Status Questionnaire. Data analysis was carried out in SPSS V. 21 software. Results: It was reported a stroke death rate of 59.9%, of which 75.7% occurred in the hospital. Stroke-related mortality rate had a significant relationship with age (P=0.021), gend...
Razi Journal of Medical Sciences, 2019
Background: MS disease has a chronic and progressive nature and affects various aspects of a pers... more Background: MS disease has a chronic and progressive nature and affects various aspects of a person's life, and results in psychological problems and poor quality of life in patients. Considering the importance of this issue, this study aimed to investigate the psychological symptoms in MS patients compared with the control group. Methods: This is a causal-comparative study in patients with MS and healthy individuals in Guilan province. In this study, 120 MS patients and 120 healthy people participated in this study. To collect the data, the Symptom CheckList-90-Revised (SCL-90-R) was used. Data were analyzed by using SPSS v.22 software and Mann-Whitney U test. Results: A survey of cutoff points for GSI showed that 68 (56.66%) of MS patients and 23 (19.16%) of healthy people were suspected of psychological disorders. The results of psychological disorder symptoms indicate that the mean score of the
Razi Journal of Medical Sciences, 2019
Background: Self-management is an important factor in the management of chronic diseases and symp... more Background: Self-management is an important factor in the management of chronic diseases and symptom control. This study aimed to investigate the effect of a psychological training program to improve self-management in MS patients in Guilan province regarding the importance of selfmanagement in multiple sclerosis (MS) patients. Methods: In this non-randomized clinical trial, 50 women with MS in Guilan province in 2018 were participated in two groups of intervention (25 people) in a voluntary manner and control (25 people) in matching. The trial was conducted in Rasht. The self-management measured by Bishop& Frain (2011) Multiple Sclerosis Self-Management Scale-Revised (MSSM-R). After receiving the pre-test, the experimental group was trained with Psychological Training Program for five weeks and that were eight sessions, but the control group did not receive any training; after five weeks, both groups received a post-test and finally, again after two months, the follow-up test recei...
Journal of Guilan University of Medical Sciences, 2014
Introduction: Cervicogenic headache is a kind of chronic headache that originates from the bony s... more Introduction: Cervicogenic headache is a kind of chronic headache that originates from the bony structures or soft tissues of the neck and is characterized by unilateral headache and lasts from hours to weeks, which can spread to the fronto-temporal and preorbital areas. So far, there has been no exact statistics of prevalence of the cervicogenic headache in Guilan Province. Objective: To determination the relative frequency of cervicogenic headache and its relative factors among patients with chronic headache Materials and Methods: In this descriptive study, the patients’ files, referred to Neurology clinic of Guilan University of Medical Sciences from March 2010 until September 2012 with complaints of chronic headache, were assessed. We used cervicogenic headache international study group diagnostic criteria for diagnosis of cervicogenic headache. The data were recorded in the special form of information and the relative frequency of cervicogenic headache was determined among them...
Iranian Journal of Neurology, 2017
Background: Stroke is the leading cause of death and functional disability. While there have been... more Background: Stroke is the leading cause of death and functional disability. While there have been major advances regarding the management of stroke, a significant proportion of people are still unaware of stroke-related symptoms and risk factors. This study was performed to assess the awareness of stroke’s warning signs and risk factors among a sample of Iranian population. Methods: A total of 649 participants were randomly selected using systematic randomization from the list of telephone numbers obtained from the telephone directory. Demographic characteristics were recorded. Participants were asked to answer questions regarding the awareness about stroke, its warning signs and risk factors. Results: Patients’ mean age was 32.0 ± 12.2 years old, and 56.4% were women. Hypertension and history of stroke were major risk factors, and loss of consciousness, vertigo and ataxia were major warning signs of stroke correctly identified by respondents. Multiple linear regressions showed that...
International Clinical Neuroscience Journal, 2015
Background and Purpose: Disc herniation leading to radiculopathy is one of the important differen... more Background and Purpose: Disc herniation leading to radiculopathy is one of the important differential diagnosis of low back pain which needs specific medical care. Radiculopathies can be initially diagnosed by history taking and physical examination. However role of other diagnostic methods like Magnetic resonance imaging (MRI) and Electromyography (EMG) in narrowing differential diagnosis is warranted when clinical data are inconsistent or inadequate. In this study we evaluated level of agreements among three methods of radiculopathy diagnosis including EMG, MRI and physical exam. Methods: This study is a comparative cross sectional study on 384 patients which was performed among patients who were referred to electrodiagnosis center for their back pain . Results from 3 questionnaires that filled by neurosurgeon for clinical results, radiologist for MRI findings and neurologist for electrodiagnosis findings were psychometrically analyzed using Kappa index for agreement among three m...
Journal of Shahid Sadoughi University of Medical Sciences, 2021
Introduction: The aim of this study was to compare eating behaviors in the patients with multiple... more Introduction: The aim of this study was to compare eating behaviors in the patients with multiple sclerosis (MS) with recurrence of the disease in the past year and the control group. Methods: This analytical cross-sectional study was a comparison that was performed in the statistical population of two groups of people with MS in Guilan Province in the second half of 2018. The first group consisted of people with MS with a recurrence of the disease in the past year and the second group of people with MS without a history of recurrence of the disease in the past year that were selected by matching the variables of age, sex and duration of the disease. In each of these groups, 104 people were employed as a sample in a targeted method from medical centers in Rasht. In order to collect data demographic information form and Dutch Eating Behaviour Questionnaire were used. Research data were analyzed by independent t-test using SPSS software version 16. Results: The results showed that amo...
Iranian Journal of Neurosurgery, 2021
Background and Aim: The present study aimed to use the median nerve Compound Muscle Action Potent... more Background and Aim: The present study aimed to use the median nerve Compound Muscle Action Potential (CMAP) amplitude by stimulation at the palm instead of Abductor Pollicis Brevis (APB) needle Electromyography (EMG) for determining axonal loss in patients with Carpal Tunnel Syndrome (CTS). Methods and Materials/Patients: This study was performed on 180 patients with CTS referred to the Electrodiagnostic (EDX) Center, Poursina Hospital, Guilan Province, Iran, in 2018-19. In this study, the APB needle EMG diagnostic test was used as the gold standard, and median nerve CMAP amplitude with stimulation at the palm and wrist were used to compare the two nerve stimulation tests. Results: All of the cases with abnormal amplitude loss detected by median nerve stimulation at the palm also had an axonal loss in the needle EMG of APB. So this test could be a good indicator of axonal loss if there is an abnormality (sensitivity: 73%, specificity: 100%). The results with wrist stimulation were n...
Caspian Journal of Health Research, 2020
Background: The aim of this study was to investigate the direct and indirect effects of selfmanag... more Background: The aim of this study was to investigate the direct and indirect effects of selfmanagement on Nutrition Behavior (NB) with the mediating role of Psychological Capital (PC) in People with Multiple Sclerosis (PwMS) in Gilan province. Methods: We studied PwMS in Guilan MS Society (GMSS) in a cross-sectional design research in 2019. We invited 275 PwMS to participate in the study either through convenience sampling method. Data collection tool consisted of questions about demographic characteristics of participants, a revised form of Multiple Sclerosis Self-Management Scale (MSSM-R), Psychological Capital Questionnaire (PCQ), and Health-Promoting Lifestyle Profile II (HPLP-II). Data were analyzed using Pearson correlation coefficient and Structural Equation Modeling (SEM) in SPSS 19.0 and Amos 18.0 statistical software. Results: The results showed that nutrition has a significant positive correlation with selfmanagement (r = 0.342), self-efficacy (r = 0.211), optimism (r =0.208), hope (r = 0.316), resiliency (r = 0.237), and PC (r = 0.287) (P-value < 0.001). Additionally, the results showed that the direct and indirect effect of self-management on nutrition was significant and the proposed model had a good data fitting. The VAF index showed that 18% of the total effect of selfmanagement on nutrition behavior is indirectly explained by the mediating variable of psychological capital. Conclusion: Self-management and PC were associated with NB in PwMS. The results of this study support the importance of these factors in health-promoting behaviors with regard to NB and the proposed model can be a suitable option in health care and nursing provided that, the fit of this model is investigated in future research and other provinces.
Neurological Sciences, 2021
Background Guillain-Barré syndrome (GBS) is the main cause of acute and subacute flaccid paralysi... more Background Guillain-Barré syndrome (GBS) is the main cause of acute and subacute flaccid paralysis in western nations since the eradication of poliomyelitis. Objective The aim of this study is to investigate epidemiology and mortality characteristics of GBS in the north of Iran. Material and methods In this study, the hospital information system (HIS) was used to access each patient's information. The final 174 cases were examined in terms of age, sex, place of residence, the year of referral, the month of referral, the season of referral, client city, accompanying background disease, and the type of GBS. Results The mean incidence rate in Guilan province was about 0.69 in 100,000 persons, and the case fatality rate was 10.34%. The most reported type of GBS was AIDP (33.90%), and the most common symptom was upper and lower limbs paresis in 65 cases (37%). Respiratory distress (P = < 0.001), complications during hospitalization (P = 0.0001), and ICU requirement (P = 0.001) were significantly higher in dead patients. Conclusion In this study, the incidence of GBS was higher in men than women and the highest number of cases was in the age group of 60 to 75 years. The significant point was the high-case fatality rate in Guilan province compared to the previous studies. The complications during hospitalization such as respiratory distress, ICU requirement, and underlying disease had a significant relation with the fatality of GBS.
Caspian Journal of Neurological Sciences, 2020
Background: Intravenous (IV) recombinant tissue Plasminogen Activator (rtPA) (IV-rtPA) is the onl... more Background: Intravenous (IV) recombinant tissue Plasminogen Activator (rtPA) (IV-rtPA) is the only FDA-approved pharmacological therapy for treatment in acute ischemic stroke and the administration of IV-rtPA is crucially time-dependent. Objectives: This study aimed to evaluate symptom-to-needle time and factors associated with the prehospital delay in patients with acute ischemic stroke referred to Poursina Hospital, a referral hospital in the north of Iran. Materials & Methods: In this cross-sectional study, all patients with acute stroke referred to Poursina Hospital from June to December 2016 were evaluated. The study data were extracted from the patients’ records. SPSS v. 21 was used to analyze the obtained data. The independent samples t-test and the Chi-square test were used to explore the appropriate relation of variables. Results: A total of 322 patients were included. Their mean age was 74.4 years and 55.6% were male. According to findings, only 74 patients (22.98%) were t...
Caspian Journal of Neurological Sciences, 2020
Background: During the COVID-19 pandemic, besides the most prevalent respiratory and systemic sym... more Background: During the COVID-19 pandemic, besides the most prevalent respiratory and systemic symptoms, some neurological symptoms such as acute hemorrhagic necrotizing encephalopathy and myelitis associated with COVID-19 have been reported. It is suspected that COVID-19 involves different body systems via interaction with the ACE-2 (angiotensin-converting enzyme 2) receptor. As ACE2 is expressed on the surface of central nervous system cells, including the brain and spine, these kinds of manifestations are inevitable. Clinical Presentation and Intervention: Here we report a case of COVID-19 associated with acute myelitis in an infected patient in the north of Iran during the pandemic of COVID-19. He presented with paraparesis and urinary incontinence. Unfortunately, he did not respond to anti-inflammatory treatment. Conclusion: Para/Post Infectious myelitis could be a complication of COVID-19 infection.
Basic and Clinical Neuroscience Journal, 2018
Introduction: Bacterial meningitis is an acute infectious inflammation of the protective membrane... more Introduction: Bacterial meningitis is an acute infectious inflammation of the protective membranes covering the brain. Its early diagnosis is vital because of its high morbidity and mortality. It is mostly diagnosed by a gold standard diagnostic tool i.e. Cerebrospinal Fluid (CSF) analysis. However, it is sometimes difficult and or impossible to do this procedure and an alternative diagnostic tool is needed. Contrast enhanced magnetic resonance imaging can detect the pus or other changes in subarachnoid space. But our optimal aim is to use an imaging method without using contrast to be useable and available in more specific condition. Methods: This study aimed to survey the role of non-contrast Magnetic Resonance Imaging (MRI) in the diagnosis of the bacterial meningitis. MEDLINE/PubMed Central, Web of Science and Scopus were searched without time period and language limitation until March 2017. We found 6410 papers in our initial search. After assessing the content of the papers based on Cochrane library guidelines and inclusion/exclusion criteria, 6 relevant studies were included in the systematic review. All of included studies were observational studies. Results: MRI studies demonstrated that Fluid Attenuation Inversion Recovery (FLAIR) and Diffusion-Weighted Image (DWI) MR imaging among all MRI modalities can detect some abnormalities compatible with bacterial meningitis. FLAIR and DWI-MR imaging are potentially useful to diagnose bacterial meningitis and can be used in emergent condition in which bacterial meningitis is highly suspicious and the other diagnostic tools are not available or feasible.
Journal of Shahid Sadoughi University of Medical Sciences, 2019
Introdution: Multiple sclerosis is a chronic disease in the nervous system; It has many problems ... more Introdution: Multiple sclerosis is a chronic disease in the nervous system; It has many problems due to its chronic and promising nature. The treatment of this disease includes medical care and empowerment interventions for symptom management. The purpose of this study was to review the empowerment interventions in these patients. Methods: This study was conducted in a Systematic Reviewperiod from January 2000 to June 2018. On indexing sites “Magiran, PubMed, Google Scholar and Science Direct” searched the key words of Multiple Sclerosis, Chronic Disease, Quality of Life, Self-care, Self-management, Rehabilitation, Empowerment, Psychotherapy, Psychological interventions, Clinical Trials, and Randomized Clinical Trial. Out of 1855 articles found, 33 articles were selected for review. Results: The results of this study showed that empowerment interventions in people with MS can be divided into four categories of self-care, self-management, rehabilitation and psychotherapy intervention...
Caspian Journal of Neurological Sciences, 2015
Background: Temporal variation of stroke onset is suggested in some studies contained somewhat va... more Background: Temporal variation of stroke onset is suggested in some studies contained somewhat varieties. It is proposed that some predisposing changes occur in some ascertained times consequently resulted in stroke occurrence in some special times. Objective: To determine the circadian and circaseptan variation of stroke onset. Materials and Methods: This cross sectional study was conducted from March 2012 to February 2013 in an academic hospital in the North of Iran. All patients with acute onset of neurological symptoms were enrolled in the study after being diagnosed as a stroke patient. The diagnosis was made by a neurologist using brain imaging. Age, gender, history of diabetes and hypertension, time and date of stroke onset were recorded for all patients. The data were analysed using Chi-square test in SPSS software version19. Results: A total of eight hundred sixty-nine patients with mean age of 67.5±12.4 years (55.6% women 44.4% men) were admitted during one year study. Eighty-five percent of stroke cases were ischemic in nature and the others were hemorrhagic type. Distribution of cases during a day was not uniform (p < 0.0001). The peak of stroke onset occurred in the mornings (7-9 a.m.) followed by a second peak in the evenings (7-9 p.m.). In addition, the distribution of cases during the week was also not uniform (p < 0.016). Conclusion: Stroke occurrence has a diurnal variation probably resulted from circadian physiologic changes. Although there is a circaseptan variation in the times of stroke record, it seemingly isn't related to physiologic changes.
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Papers by Mozaffar Hosseininezhad