Papers by Lesmana Lesmana
International hepatology …, 1996
Of 153 patients with chronic liver disease in Jakarta, Indonesia, who were positive for antibody ... more Of 153 patients with chronic liver disease in Jakarta, Indonesia, who were positive for antibody to hepatitis C virus (HCV), 129 (84%) had HCV RNA in serum. HCV genotypes were II/lb in 55 (43%), 111/2a in 33 (26%) and lc in 15 (12%) patients; genotypes were not classifiable into the common five (I/la, II/lb, 111/2a, IVj2b and V/3a) or lc in the remaining 25 (19%) patients. RNA of a putative non-A-E hepatitis virus, designated GB virus C (GBV-C), was tested for by reverse-transcription polymerase chain reaction with nested primers deduced from the 5'-noncoding region, and detected in 18 (12%) patients of whom 14 (78%) possessed serum HCV RNA. These results indicate that lc and the other indigenous genotypes of HCV, as well as the co-infection with GBV-C, would be common among Indonesian patients with HCV-associated chronic liver disease.
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Papers by Lesmana Lesmana