Papers by Leonard Berliner
International journal of computer assisted radiology and surgery, Apr 12, 2024
Der virtuelle Patient, 2014
Radiology Case Reports, 2021
Atypical or unilateral polycystic kidney disease is a rare entity that is found incidentally and ... more Atypical or unilateral polycystic kidney disease is a rare entity that is found incidentally and is characterized on imaging as asymmetric or unilateral distribution of cysts confined to the kidneys. We present a case of an incidental finding of atypical polycystic kidney disease in a 72-year-old male. Computed tomography imaging showed asymmetric distribution of cysts only in the kidneys and the patient had no genitourinary symptoms, had normal renal function, and did not have a family history of renal disease. Although considered to be benign, rare cases of progression of atypical polycystic kidney disease to bilateral polycystic kidney disease has been documented in the literature, which portends a worse prognosis. It is important for clinicians to be aware of this entity so that patients can be monitored periodically for progression of disease.
Medical Journal of Australia, 1981
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2005
The goal of this research project is to develop a fast, accurate, and patient-friendly computer-a... more The goal of this research project is to develop a fast, accurate, and patient-friendly computer-aided diagnosis (CAD) component of CT colonography, that improves the robustness and accuracy of current colon wall segmentation and achieves earlier colorectal cancer diagnoses through an improved polyp detection method. Many advanced image processing techniques are applied to clearly outline the colon wall in the CT data set of human abdomen, and subtract the colon portion from the entire data set. After the subtraction, the detailed information and the surface curvature information on the colon wall is analyzed. The active contour model is assisted by presegmentation steps including mathematical morphology filtering, edge detection and other image processing techniques.
Urologic radiology, 1982
Abstract A case of renal infarction accompanying bacterial endocarditis, which was diagnosed by c... more Abstract A case of renal infarction accompanying bacterial endocarditis, which was diagnosed by computed tomography (CT), is presented. The pathophysiology of renal infarction, which accounts for the CT findings observed in this case, is reviewed. In the ...
International Congress Series, 2005
CT Colonography (CTC) has been developed as an alternative method to conventional colonoscopy for... more CT Colonography (CTC) has been developed as an alternative method to conventional colonoscopy for the early detection of colonic polyps. However, there still remain limitations which preclude its widespread use. This research provides an enhanced computer-processing methodology for the CAD component of CT Colonography, which will improve upon the current methods of CT Colonography. The techniques developed in this research include: (1) development of a segmentation process employing Active Contour Modeling and Gray Scale Analysis, and (2) development of a unique 3-Component Viewing System.
IEEE Transactions on Robotics, 2018
A ppbv-level quartz-enhanced photoacoustic spectroscopy (QEPAS)-based ethane (C 2 H 6) sensor was... more A ppbv-level quartz-enhanced photoacoustic spectroscopy (QEPAS)-based ethane (C 2 H 6) sensor was demonstrated by using a 3.3 µm continuous-wave (CW), distributed feedback (DFB) interband cascade laser (ICL). The ICL was employed for targeting a strong C 2 H 6 absorption line located at 2996.88 cm −1 in its fundamental absorption band. Wavelength modulation spectroscopy (WMS) combined with the second harmonic (2f) detection technique was utilized to increase the signal-to-noise ratio (SNR) and simplify data acquisition and processing. Gas pressure and laser frequency modulation depth were optimized to be 100 Torr and 0.106 cm −1 , respectively, for maximizing the 2f signal amplitude. Performance of the QEPAS sensor was evaluated using specially prepared C 2 H 6 samples. A detection limit of 11 parts per billion in volume (ppbv) was obtained with a 1-s integration time based on an Allan-Werle variance analysis, and the detection precision can be further improved to~1.5 ppbv by increasing the integration time up to 230 s.
Dynamic Systems and Control, Volumes 1 and 2, 2003
This paper addresses methods for determining the motion of an elastically suspended rigid body in... more This paper addresses methods for determining the motion of an elastically suspended rigid body interacting with frictional surfaces at multiple locations. The methods developed assume: 1) that the motion of the base from which the body is suspended and the elastic behavior of the suspension are known, 2) that inertial forces are negligible (motion is quasi-static), and 3) that the interaction is characterized by Coulomb friction. The derived coupled sets of spatial rigid body equations are used to determine both the unknown direction of the friction force (at each point of contact) and the unknown motion of the rigid body.Copyright © 2003 by ASME
International Journal of Computer Assisted Radiology and Surgery, 2022
Purpose For over three decades, the Computer-Assisted Radiology and Surgery (CARS) International ... more Purpose For over three decades, the Computer-Assisted Radiology and Surgery (CARS) International Congress and Exhibition has provided a forum for the presentation of innovations in computer applications in radiology, medicine, and surgery. A unique feature of the CARS meetings is the interplay between scientists, engineers, and physicians. Since 2007, a Clinical Day program was introduced to the Congress highlighting the practical applications of new technology within the context of clinical medical and surgical practice. Methods The Clinical Day of the CARS Congress allows cross-fertilization of ideas between technologically oriented engineers and clinically oriented physicians; two groups who typically have little interaction. Activities of the Clinical Day include presentations by invited speakers, presentations of Innovative Clinical Investigations, a Panel Discussion and Open Forum, and, most recently, real-time clinical presentations with professionally prepared scholarly videos. Special consideration is given to young researchers and students. There has been an explosion of interest in the Clinical Day with continued and growing interest in Artificial Intelligence, Computer-Assisted Surgery, and new scientific breakthroughs as they become linked to clinical applications. Results Success of the Clinical Day is emphasized by increased participation and efforts to expand the scope and depth of Clinical Day activities. The Open Forum has proven to be highly effective in identifying important new technologic challenges in medicine and promoting discussion among those whose expertise likely can lead to solutions. Conclusions The original goal of the Clinical Day, to provide an effective means to "bridge the gap" between the engineering community and practicing physicians and surgeons, has been realized through the presentation and discussion of real-life, clinical material that utilizes advanced technology. The program has served to inspire young researchers by allowing them to see the end results of their laboratory investigations, thereby gaining a greater appreciation of the importance of their work.
Advances in Predictive, Preventive and Personalised Medicine, 2015
The use of general descriptive names, registered names, trademarks, service marks, etc. in this p... more The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
Annals of Emergency Medicine
International Journal of Computer Assisted Radiology and Surgery
This editorial provides some initial concepts on how the content of IJCARS publications, specific... more This editorial provides some initial concepts on how the content of IJCARS publications, specifically those that have been accepted for the CARS Congress and CARS Academy, may be reflected in high-quality video presentations with a focus on Facts, Figures and Thoughts (FFT). The overarching purpose of the scholarly publication and communication process of IJCARS in the context of CARS (Computer Assisted Radiology and Surgery) as a scientific/ medical domain could be defined as: "To enable the exchange/communication of R&D ideas by means of verbal and written statements made by responsible authors, scrutinized by informed reviewers and utilized by an open-minded audience, with the aim to stimulate complimentary thoughts and actions within the given domain of discourse by all parties involved in the scientific/medical communication process". With this definition in mind, author-machine-audience communication by means of video presentations is in the process of becoming part of a new communication culture for CARS Congresses and the CARS Academy. It implies a
International journal of computer assisted radiology and surgery, Jan 15, 2017
Oncological treatment is being increasingly complex, and therefore, decision making in multidisci... more Oncological treatment is being increasingly complex, and therefore, decision making in multidisciplinary teams is becoming the key activity in the clinical pathways. The increased complexity is related to the number and variability of possible treatment decisions that may be relevant to a patient. In this paper, we describe validation of a multidisciplinary cancer treatment decision in the clinical domain of head and neck oncology. Probabilistic graphical models and corresponding inference algorithms, in the form of Bayesian networks, can support complex decision-making processes by providing a mathematically reproducible and transparent advice. The quality of BN-based advice depends on the quality of the model. Therefore, it is vital to validate the model before it is applied in practice. For an example BN subnetwork of laryngeal cancer with 303 variables, we evaluated 66 patient records. To validate the model on this dataset, a validation workflow was applied in combination with q...
BMC Cancer, 2016
Background: Patients with primary and metastatic liver malignancies represent a highly heterogene... more Background: Patients with primary and metastatic liver malignancies represent a highly heterogeneous patient pool characterised by some of the shortest life expectancies amongst oncology patients. Investigation and better understanding of liver malignancies is an emerging field which requires high-quality multidisciplinary research and collaboration. Methods: A study of 158 patients with primary hepatic carcinomas and secondary liver metastases, altogether 15 cancer types of different origin, who underwent selective internal radiation therapy (SIRT) with Yttrium 90 or transarterial chemoembolisation, was undertaken in an effort to detect distinguishing features with respect to activity profiles of both blood matrix metalloproteinase (MMP-2 and MMP-9). Results: Noteworthy, stratification of all hepatic cancer groups with respect to MMP-2 and MMP-9 activities revealed characteristic patterns specifically in patients with hepatic breast cancer metastases who had undergone SIRT. In contrast to all other groups, these patients demonstrated well-consolidated profiles of both MMPs, reflecting a common feature, namely an immediate and durable increase of their activity after the SIRT treatment. Although the total number of patients in the breast cancer group is relatively small (15 patients), since increased activities of MMP-2 and MMP-9 are well known prognostic factors for poor outcomes of oncologic patients, the significance and clear group-specificity (from 15 ones investigated here) of this previously unanticipated finding requires particular attention and further investigations. Particularly important is to determine, whether this increase of the metalloproteinase activity was provoked by SIRT, as well as whether special selection criteria are required for patients with breast cancer metastases to the liver who are being considered for SIRT. Conclusions: It is recommended that a more focused, multidisciplinary and large-scaled investigations of the possible adverse effects of SIRT in patients with advanced metastatic disease of breast cancer be undertaken, with an appropriate patients' stratification, setup of the relevant patient profiles and disease modelling.
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Papers by Leonard Berliner