Papers by Julio Marco Sanchéz Jiménez
International journal of molecular sciences, Jan 24, 2016
Bronchopulmonary dysplasia (BPD) is caused by preterm neonatal lung injury and results in oxygen ... more Bronchopulmonary dysplasia (BPD) is caused by preterm neonatal lung injury and results in oxygen dependency and pulmonary hypertension. Current clinical management fails to reduce the incidence of BPD, which calls for novel therapies. Fetal rabbits have a lung development that mimics humans and can be used as a translational model to test novel treatment options. In preterm rabbits, exposure to hyperoxia leads to parenchymal changes, yet vascular damage has not been studied in this model. In this study we document the early functional and structural changes of the lung vasculature in preterm rabbits that are induced by hyperoxia after birth. Pulmonary artery Doppler measurements, micro-CT barium angiograms and media thickness of peripheral pulmonary arteries were affected after seven days of hyperoxia when compared to controls. The parenchyma was also affected both at the functional and structural level. Lung function testing showed higher tissue resistance and elastance, with a dec...
Technovation, 1999
This paper tries to ascertain the validity of Kalman Filtering in forecasting technological subst... more This paper tries to ascertain the validity of Kalman Filtering in forecasting technological substitution. It is also concerned with this process in the Spanish Telecommunications Sector. With that aim, the ability of this methodology and that of Ordinary Least Square in describing and forecasting the different substitution processes that have taken place in this sector are compared. Some conclusions are drawn from the different speeds of substitution observed between both processes, and it is also stated that Kalman Filtering is superior to Ordinary Least Square, both in estimating and in forecasting in the short term.
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Papers by Julio Marco Sanchéz Jiménez