Papers by Jonathan Abella
Circulation, 2007
Background— Ventilatory efficiency, commonly assessed by the minute ventilation (V̇ e )–carbon di... more Background— Ventilatory efficiency, commonly assessed by the minute ventilation (V̇ e )–carbon dioxide production (V̇ co 2 ) slope, is a powerful prognostic marker in the heart failure population. The purpose of the present study is to refine the prognostic power of the V̇ e /V̇ co 2 slope by developing a ventilatory class system that correlates V̇ e /V̇ co 2 cut points to cardiac-related events. Methods and Results— Four hundred forty-eight subjects diagnosed with heart failure were included in this analysis. The V̇ e /V̇ co 2 slope was determined via cardiopulmonary exercise testing. Subjects were tracked for major cardiac events (mortality, transplantation, or left ventricular assist device implantation) for 2 years after cardiopulmonary exercise testing. There were 81 cardiac-related events (64 deaths, 10 heart transplants, and 7 left ventricular assist device implantations) during the 2-year tracking period. Receiver operating characteristic curve analysis revealed the overall ...
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Papers by Jonathan Abella