Papers by Jitendra Sharan
PubMed, May 8, 2023
Various systemic diseases can manifest oral signs and symptoms early, which may be crucial for di... more Various systemic diseases can manifest oral signs and symptoms early, which may be crucial for diagnosis and outlining the treatment plan. This case report highlights the presentation of acute leukemia (a malignancy of white blood cells) in a young female. An 11-year-old girl presented with gingival overgrowth and bleeding from the gingiva, weakness, and recent history of weight loss. A detailed workup consisting of complete blood count, bone marrow examination, flow cytometric immunophenotyping, cytogenetics, and molecular studies were carried out. The investigations confirmed the infiltration of blast cells of myelomonocytic origin, and a confirmatory diagnosis of acute myeloid leukemia (French-American-British classification M5) was made. The patient was put on induction chemotherapy and responded well. She developed febrile neutropenia following chemotherapy, which was managed conservatively. Gingival overgrowth subsided after the chemotherapy, and at the time of discharge, she was asymptomatic and hemodynamically stable. The oral health-care professionals must recognize that gingival overgrowth/enlargement may represent an initial manifestation of an underlying systematic disease.
Research Square (Research Square), Feb 1, 2023
Objectives: To assess the outcome of L-PRF on the rate of maxillary canine retraction and its cor... more Objectives: To assess the outcome of L-PRF on the rate of maxillary canine retraction and its correlation with the levels of RANKL and OPG in the GCF. Subjects and Methods: Eighteen females who required all 1 st premolars extraction for the correction of their Class-I bimaxillary protrusion malocclusions were included. The L-PRF plugs were placed in the experimental side 1 st premolar extraction sockets. Canine retraction was performed by sliding mechanics. Canine retraction was assessed from the maxillary study models prepared just before the extraction (T 0), then at 1-week (T 1
American Journal of Orthodontics and Dentofacial Orthopedics, Jul 1, 2022
Trends in biomaterials & artificial organs, Jul 15, 2021
Oral Diagnostics Tools and Techniques
International Journal of Dentistry
Objective. The aim of the study is to identify the normal vertical positions of sella (S) and nas... more Objective. The aim of the study is to identify the normal vertical positions of sella (S) and nasion (N) points in subjects with a normal inclination of anterior cranial bases. Materials and Methods. Lateral cephalograms of 117 subjects who had a normal ∠SN-FH plane (7° ± 1°), ∠SN-palatal plane (9° ± 2°), ∠FH-palatal plane (1° ± 1°), and cranial base angles (131° ± 4°) were included in the study. Various linear and angular parameters and ratios were evaluated to determine the normal vertical positions of S and N points. An unpaired t-test was used to identify any significant differences between males and females. The P value of 0.05 was considered as the level of significance. Results. Among subjects with the normal inclinations of SN, FH, and palatal planes and cranial base angle, the mean values of ∠Ar-S-Ptm, ∠S-Ptm-Ar, and ∠S-Ar-Ptm were 59.38° ± 3.52°, 59.70° ± 3.21°, and 60.84° ± 3.56°, respectively, forming an almost equilateral triangle between S, Ar, and Ptm points. The mean...
International Orthodontics
The specialty of orthodontia has evolved over the years in terms of material science, technology,... more The specialty of orthodontia has evolved over the years in terms of material science, technology, treatment efficient, precision engineering and other related aspects. Conventional wisdom in business world says that to grow, you have to first sustain, explore the options and then expand. The same notion holds true for orthodontic clinical practice as well. Nevertheless, practice governance and management are the least explored entities amongst the orthodontists with basic knowledge in information technology, behavioral management, finance & taxation, law & litigation and professional ethics, it is conceivable to manage and maintain an orthodontic practice that is self-sustainable and can be seen as professional model for other specialties.
This case report describes the unusual location of the distobuccal root canal in a maxillary seco... more This case report describes the unusual location of the distobuccal root canal in a maxillary second molar with root fusion. On access opening, three distinct root canal orifices, the mesiobuccal canal, palatal canal, and a third orifice closer to the palatal canal, were seen, giving an illusion of an additional palatal canal. An attempt was made to search for the distobuccal canal in its usual position, leading to the gouging of the pulp chamber floor. An intra-operative limited field of view cone-beam computed tomography (CBCT) revealed the root orifice adjacent to the palatal canal was the distobuccal canal. CBCT also revealed fusion of both the buccal and palatal roots in the root's coronal and middle third region, but they were not fused apically.
Clinical Oral Investigations
Objectives To assess the outcome of leukocyte-platelet-rich fibrin (L-PRF) on the rate of maxilla... more Objectives To assess the outcome of leukocyte-platelet-rich fibrin (L-PRF) on the rate of maxillary canine retraction and its correlation with the levels of Receptor activator of nuclear factor kappa-B ligand (RANKL), osteoprotegerin (OPG), and RANKL:OPG in the gingival crevicular fluid (GCF) during comprehensive orthodontic treatment. Subjects and methods Eighteen females who required all 1st premolars extraction for the correction of their class I bimaxillary protrusion malocclusions were included. The L-PRF plugs were placed in the experimental side 1st premolar extraction sockets. Canine retraction was performed by sliding mechanics. Canine retraction was assessed from the maxillary study models prepared just before the extraction (T 0) and then at 1 week (T 1), 2 weeks (T 2), 4 weeks (T 3), and 8 weeks (T 4
Turkish Journal of Orthodontics
Main Points • The retraction of incisors does not affect the sagittal dimensions of the upper air... more Main Points • The retraction of incisors does not affect the sagittal dimensions of the upper airway. • The sagittal thickness of the posterior pharyngeal wall decreases significantly as an adaptation to maintain the patency of the upper airway following the retraction of incisors. • The adaptive changes in the posterior pharyngeal wall occur mainly at the retropalatal and retroglossal regions. • The adaptive change in the posterior pharyngeal wall can be considered as a risk factor for future sleep-disordered breathing development.
Journal of Oral Biology and Craniofacial Research
American Journal of Orthodontics and Dentofacial Orthopedics
Journal of Indian Orthodontic Society
Objective To have an understanding of the fact how the popularity of “do it yourself” (DIY) video... more Objective To have an understanding of the fact how the popularity of “do it yourself” (DIY) videos available on YouTube correlate with authorship, content, quality, reliability, and how they appeal to and influence the customers. Materials and Methods A new YouTube account was created, this was followed by a determination of the most commonly used keywords regarding DIY aligners by using “Google Trends.” The keywords were used to search the YouTube website. A total of 112 videos were assessed for various parameters, such as completeness of the content, reliability using a modified version of the DISCERN tool, and quality using a Global Quality Score (GQS). Out of 112 videos, 26 were rejected based on their relevance, duplication, videos without audio, and video language. Pearson’s correlation coefficient was used to study the relationship between the variables, authorship, popularity, and recommendations. Results The majority of the videos were uploaded by the laypeople (43%), follo...
International Journal of Orthodontic Rehabilitation
An 11-year-old female patient presented with a chief complaint of labially blocked out maxillary ... more An 11-year-old female patient presented with a chief complaint of labially blocked out maxillary canines and irregular teeth in the upper arch. Clinical examination and evaluation revealed an Angle's Class II malocclusion on an underlying Class II skeletal base with a crowded maxillary arch, blocked out maxillary canines, mild crowding in the mandibular arch, convex profile, and obtuse nasolabial angle. Her skeletal maturity status was Stage III of the cervical vertebrae maturity index (CVMI). A nonextraction treatment plan was considered for this case, which involves bilateral permanent first molar distalization of the maxillary arch using Jones jig distalizer followed by fixed orthodontic mechanotherapy using 022 MBT prescription. The posttreatment outcome shows an appreciable improvement in facial esthetics and occlusion. Further postorthodontic phase has retained a stable occlusion and pleasing facial profile.
Trends in biomaterials & artificial organs, Jul 15, 2021
International Journal of Applied Dental Sciences, 2022
The coronavirus disease (COVID-19) has imposed severe restrictions where all healthcare facilitie... more The coronavirus disease (COVID-19) has imposed severe restrictions where all healthcare facilities except emergency services were either curtailed or suspended. Teleconsultation at that point time was the only mode to get in touch with the consultant for health care needs. Further teledentistry can enhance access to oral health care, increase the provision of oral health care, and reduce cost. This paper gives an insight into teledentistry practice at the
Orthodontic Journal of Nepal, 2021
Introduction: Sleep-disordered breathing (SDB) is one of the poorly diagnosed disorders which aff... more Introduction: Sleep-disordered breathing (SDB) is one of the poorly diagnosed disorders which affects the quality of life of patients. The SDB is a spectrum of problems ranging from simple snoring to obstructive sleep apnoea (OSA) which involves complete collapse of the pharyngeal airway passage during sleep resulting in airflow cessation and consequent arousals. A noteworthy etiological factor of OSA is mandibular retrognathism. Imaging studies on craniofacial structures in OSA patients have shown decreased oropharyngeal and hypopharyngeal depth, elongated soft palate, altered tongue posture, and increased hyoid bone-to-mandible distance. The management modalities of OSA are positive airway pressure (PAP) and oral appliance therapy. The modus operandi of mandibular advancement devices (MADs) is the same as of myofunctional therapy instituted by orthodontists for the treatment of skeletal Class II malocclusions with mandibular retrusion in growing patients. By virtue of the increase...
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Papers by Jitendra Sharan