Papers by Jawahar Ganapathy
The present study revealed that the value added products developed from Calocybe indica (C.indica... more The present study revealed that the value added products developed from Calocybe indica (C.indica) had good storage period, nutritive value. As months progressed, the biochemical composition of C. indica chutney powder was found to be decreased when compared to the initial levels. A gradual increase in total plate count was observed for the product during storage period. No remarkable changes were observed for organoleptic characteristics of chutney powder prepared from C.indica. The sensory scores of chutney powder remained within the acceptable limit throughout the storage period. The overall acceptability of products ranged from 8.5±0.21 to 7.1±0.31 during the storage period. No spoilage occurred during the storage period. This could be the preservative action of ingredients on food products till the 6 month of storage period. Based on observations, it was found that the value added products would be included as a regular diet, since it possess rich nutritive value. Thus the pres...
Asian Journal of Pharmaceutical and Clinical Research, 2018
Objective: The present study deals with dietary supplementation of Pleurotus ostreatus and Calocy... more Objective: The present study deals with dietary supplementation of Pleurotus ostreatus and Calocybe indica in Swiss male albino mice in comparison with casein control diet.Methods: The Swiss albino male mice were divided into four groups. Group 1 served as normal, Group II served as control mice, and Groups III and IV mice were fed with food supplement P. ostreatus and C. indica for 28 days. After 28 days, the animals were euthanized by cervical dislocation, and liver samples were used to analyze the following parameters such as superoxide dismutase (SOD), catalase, glutathione peroxidase, reduced glutathione (GSH), Vitamin C, and Vitamin E.Results: The results of the present study indicated that dietary supplementation of P. ostreatus and C. indica significantly…
Bioinformation, 2007
Gene function annotation remains a key challenge in modern biology. This is especially true for h... more Gene function annotation remains a key challenge in modern biology. This is especially true for high-throughput techniques such as gene expression experiments. Vital information about genes is available electronically from biomedical literature in the form of full texts and abstracts. In addition, various publicly available databases (such as GenBank, Gene Ontology and Entrez) provide access to gene-related information at different levels of biological organization, granularity and data format. This information is being used to assess and interpret the results from highthroughput experiments. To improve keyword extraction for annotational clustering and other types of analyses, we have developed a novel text mining approach, which is based on keywords identified at the level of gene annotation sentences (in particular sentences characterizing biological function) instead of entire abstracts. Further, to improve the expressiveness and usefulness of gene annotation terms, we investigated the combination of sentence-level keywords with terms from the Medical Subject Headings (MeSH) and Gene Ontology (GO) resources. We find that sentencelevel keywords combined with MeSH terms outperforms the typical 'baseline' setup (term frequencies at the level of abstracts) by a significant margin, whereas the addition of GO terms improves matters only marginally. We validated our approach on the basis of a manually annotated corpus of 200 abstracts generated on the basis of 2 cancer categories and 10 genes per category. We applied the method in the context of three sets of differentially expressed genes obtained from pediatric brain tumor samples. This analysis suggests novel interpretations of discovered gene expression patterns.
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Papers by Jawahar Ganapathy