Papers by Erinique Ingraham
PLOS Neglected Tropical Diseases, 2020
Background The 2005-06 chikungunya virus (CHIKV) outbreak in La Ré union suggested that mothers c... more Background The 2005-06 chikungunya virus (CHIKV) outbreak in La Ré union suggested that mothers could transmit CHIKV to their neonates while viremic during the intrapartum period, and more than half of the infected neonates showed impaired neurodevelopment at two years of age. However, data sparsity precluded an overview of the developmental impact of vertical infection within the whole prenatal period. Objective & methods The current study assessed two-year old children born to mothers who were infected during the 2014 CHIKV outbreak in Grenada to determine the neurodevelopmental impact of perinatal CHIKV infection throughout gestation. Mother and child infection status were confirmed by serologic testing (IgG and IgM) for CHIKV. Cognitive, fine motor, gross motor, language and behavioral outcomes were assessed at two years of age on the INTER-GROWTH-21 st Neurodevelopment Assessment (INTER-NDA). Results No differences in neurodevelopmental outcomes were observed between two-year-old children born to mothers infected with CHIKV during gestation (n = 149) and those born to mothers not infected with CHIKV (n = 161). No differences were found in INTER-NDA scores PLOS NEGLECTED TROPICAL DISEASES
Uploads
Papers by Erinique Ingraham