Papers by Hadianti Adlani
The Journal of Hospital Accreditation, 2019
Latar Belakang: Standar Nasional Akreditasi Rumah Sakit (SNARS) edisi 1 (2018) menetapkan pengkaj... more Latar Belakang: Standar Nasional Akreditasi Rumah Sakit (SNARS) edisi 1 (2018) menetapkan pengkajian pengendalian resistensi antibiotik di setiap rumah sakit di seluruh Indonesia sebagai salah satu syarat akreditasi rumah sakit. Namun, dalam pelaksanaannya, kerapkali pengendalian resistensi antibiotik mengalami banyak kendala. Tujuan: Menilai persepsi anggota Panitia Pengendalian Resistensi Antimikroba (PPRA) terhadap hambatan dan kebutuhan rumah sakit dalam menjalankan peran PPRA. Metode: Dilakukan survei potong lintang dengan membagikan kuesioner kepada responden 156 rumah sakit. Responden mengisi kuesioner berupa pertanyaan tertutup pilihan berganda dan memilih satu jawaban yang paling tepat. Analisa dilakuakn secara deskriptif. Hasil: Pada survei ini diperoleh 26.92% dari 156 rumah sakit yang telah menjalankan program PPRA di rumah sakit. 65.38% menyatakan hanya sebagian dokter yang duduk sebagai anggota PPRA mampu melakukan tugasnya. 40.48% dari responden rumah sakit yang telah...
Tropical Doctor, 2017
Blood cultures for a definitive diagnosis of typhoid fever takes time and are not routinely avail... more Blood cultures for a definitive diagnosis of typhoid fever takes time and are not routinely available. We thus investigated laboratory parameters to predict Salmonella bacteraemia. We conducted a prospective cohort study in Jakarta, Indonesia. Patients with suspected typhoid fever admitted to hospital from October 2014 to December 2016 were included. Out of 187 individuals, 27 had Salmonella typhi and 12 had S. paratyphi in blood cultures. Absolute eosinopenia, elevated aspartate aminotransferase and elevated C-reactive protein > 40 mg/L were positive predictors.
Journal of Medical Case Reports
Background Patients with severe acute respiratory syndrome coronavirus 2 infection show various c... more Background Patients with severe acute respiratory syndrome coronavirus 2 infection show various clinical manifestations, including neurological . Altered consciousness due to severe acute respiratory syndrome coronavirus 2 encephalitis is a very threatening condition if not treated immediately. Case presentation We present the case of a 34-year-old Asian female who tested positive for severe acute respiratory syndrome coronavirus 2 infection using a nasopharyngeal swab sample and presented with acute changes in consciousness without typical respiratory symptoms. Empiric therapy was immediately and simultaneously given with cerebrospinal fluid analysis using polymerase chain reaction, which later also showed positive results for severe acute respiratory syndrome coronavirus 2 infection. Conclusions It is important to consider the diagnosis of severe acute respiratory syndrome coronavirus 2 encephalitis when a patient presents with acute altered consciousness and no typical respirator...
International Journal of Infection Control, 2021
Methods: A pre–post-descriptive study was conducted in 2019 for 3 months at a private hospital in... more Methods: A pre–post-descriptive study was conducted in 2019 for 3 months at a private hospital in Central Java, Indonesia, to evaluate the implementation of the Regulation on Indonesian Antimicrobial Stewardship Program (ASP), namely, the Prospective Antimicrobial System/Regulasi Antimikroba Sistem Prospektif Indonesia (RASPRO). Outcomes were measured before and after the implementation of the RASPRO in the ward including: 1) intravenous antibiotic defined daily dose (DDD) per 100 patient-days, 2) antibiotic expenditure, and 3) antibiotic expenditure per inpatient. Result: The total antibiotic consumption was expressed in DDD/100 patient-days. For the levofloxacin category, the number increased intensely from 2.38 to 15.29; carbapenem escalated from 0.51 to 2.31, ceftriaxone from 32.10 to 38.03, and ampicillin sulbactam from 1.14 to 1.18. In contrast, cefuroxime significantly reduced from 17.25 to 1.38, cefotaxime decreased from 10.33 to 6.83, gentamicin decreased from 3.18 to 1.91,...
Masalah Mutu: Standar 4 Kajian SNARS 2018 menyatakan bahwa rumah sakit wajib memiliki surveilens ... more Masalah Mutu: Standar 4 Kajian SNARS 2018 menyatakan bahwa rumah sakit wajib memiliki surveilens kepekaan kuman terhadap antibiotik. Hal ini harus menjadi dasar pertimbangan pembuatan Panduan Penggunaan Antibiotik (PPAB). Di sisi lain, timbulnya kuman Multi Drug Resistance (MDR) juga dipengaruhi oleh berbagai faktor. Pemberian antibiotik empirik, selain berdasar pada pola kuman, juga sebaiknya mempertimbangkan berbagai faktor risiko timbulnya kuman MDR. Pilihan Solusi: Regulasi Antimikroba Sistem Prospektif (RASPRO) adalah sebuah model tataguna antimikroba yang disintesis dari berbagai kepustakaan dengan mempertimbangkan berbagai faktor yang dapat menyebabkan timbulnya kuman-kuman MDR pada surveilans kepekaan kuman, sehingga dapat mengarahkan klinisi pada peresepan antibiotik bijak. Implementasi: Kajian risiko yang dibuat dalam RASPRO menentukan bahwa immunocompromised dan/ atau dengan komorbid Diabetes Melitus yang tidak terkontrol atau dengan riwayat konsumsi antibiotik kurang dar...
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Papers by Hadianti Adlani