SummaryPublication of the SHEP study (Systolic Hypertension in the Elderly Programme) leaves no d... more SummaryPublication of the SHEP study (Systolic Hypertension in the Elderly Programme) leaves no doubt that isolated systolic hypertension in the elderly should be treated. There are, however, a number of important outstanding questions: (a) the mechanism of reduction of morbidity, (b) because antihypertensive therapy appears to be more effective in elderly patients than in the young, when should treatment be started in relation to progression of age?, (c) besides the blood pressure elevation, what are the exact mechanical factors responsible for degeneration of the arterial wall?, and (d) what in 1993 is the definition of hypertension? These are questions that now need to be answered.
Hypertension is a common problem in the elderly. Its prevalence is currently 60%-80%, but it is e... more Hypertension is a common problem in the elderly. Its prevalence is currently 60%-80%, but it is estimated that it will increase with the projected population growth of older people aged more than 65 years. Hypertension is a major cardiovascular risk factor due to the well-known continuous relationship between high blood pressure, stroke and cardiovascular (CV) mortality in all age groups. Because of the expected increasing proportion of older people, a further increase in CV and renal complications of hypertension in the next few decades can be predicted. In the elderly, systolic blood pressure increases because of arterial stiffness produced by structural alterations of arterial wall occurring with aging. On the other hand, in people aged 60 years and over, diastolic blood pressure remains unchanged or decreases. Isolated systolic hypertension and high pulse pressure are thus prevalent, and are important risk factors for stroke, coronary heart disease and all-cause mortality in the...
Hypertension is a common problem in the elderly. Its prevalence is currently 60%-80%, but it is e... more Hypertension is a common problem in the elderly. Its prevalence is currently 60%-80%, but it is estimated that it will increase with the projected population growth of older people aged more than 65 years. Hypertension is a major cardiovascular risk factor due to the well-known continuous relationship between high blood pressure, stroke and cardiovascular (CV) mortality in all age groups. Because of the expected increasing proportion of older people, a further increase in CV and renal complications of hypertension in the next few decades can be predicted. In the elderly, systolic blood pressure increases because of arterial stiffness produced by structural alterations of arterial wall occurring with aging. On the other hand, in people aged 60 years and over, diastolic blood pressure remains unchanged or decreases. Isolated systolic hypertension and high pulse pressure are thus prevalent, and are important risk factors for stroke, coronary heart disease and all-cause mortality in the...
SummaryPublication of the SHEP study (Systolic Hypertension in the Elderly Programme) leaves no d... more SummaryPublication of the SHEP study (Systolic Hypertension in the Elderly Programme) leaves no doubt that isolated systolic hypertension in the elderly should be treated. There are, however, a number of important outstanding questions: (a) the mechanism of reduction of morbidity, (b) because antihypertensive therapy appears to be more effective in elderly patients than in the young, when should treatment be started in relation to progression of age?, (c) besides the blood pressure elevation, what are the exact mechanical factors responsible for degeneration of the arterial wall?, and (d) what in 1993 is the definition of hypertension? These are questions that now need to be answered.
Hypertension is a common problem in the elderly. Its prevalence is currently 60%-80%, but it is e... more Hypertension is a common problem in the elderly. Its prevalence is currently 60%-80%, but it is estimated that it will increase with the projected population growth of older people aged more than 65 years. Hypertension is a major cardiovascular risk factor due to the well-known continuous relationship between high blood pressure, stroke and cardiovascular (CV) mortality in all age groups. Because of the expected increasing proportion of older people, a further increase in CV and renal complications of hypertension in the next few decades can be predicted. In the elderly, systolic blood pressure increases because of arterial stiffness produced by structural alterations of arterial wall occurring with aging. On the other hand, in people aged 60 years and over, diastolic blood pressure remains unchanged or decreases. Isolated systolic hypertension and high pulse pressure are thus prevalent, and are important risk factors for stroke, coronary heart disease and all-cause mortality in the...
Hypertension is a common problem in the elderly. Its prevalence is currently 60%-80%, but it is e... more Hypertension is a common problem in the elderly. Its prevalence is currently 60%-80%, but it is estimated that it will increase with the projected population growth of older people aged more than 65 years. Hypertension is a major cardiovascular risk factor due to the well-known continuous relationship between high blood pressure, stroke and cardiovascular (CV) mortality in all age groups. Because of the expected increasing proportion of older people, a further increase in CV and renal complications of hypertension in the next few decades can be predicted. In the elderly, systolic blood pressure increases because of arterial stiffness produced by structural alterations of arterial wall occurring with aging. On the other hand, in people aged 60 years and over, diastolic blood pressure remains unchanged or decreases. Isolated systolic hypertension and high pulse pressure are thus prevalent, and are important risk factors for stroke, coronary heart disease and all-cause mortality in the...
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Papers by Giovanni Pompa