Papers by Georgios Chalatsis
Introduction: Femoroacetabular impingement syndrome is an important cause of hip pain in young ad... more Introduction: Femoroacetabular impingement syndrome is an important cause of hip pain in young adults. It is characterized by excess contact between the femoral neck and head and the anterior rim of the acetabulum. Purpose: The purpose of this study is to assess the reporting quality of Randomized Controlled Trials (RCTs) for Hip Arthroscopy effectiveness, in Femoroacetabular Impingement, compared to other therapeutic methods. Methods: Electronic databases of MEDLINE (Pub Med), Cohrane Library, Science Direct, Google scholar and United States Clinical trials registration from 2008 until today. From 16 scientific papers, 5 were selected as appropriate for the study. For the assessment of the randomized controlled trials the CONSORT Checklist was used assessing the report of the 37 key terms. Results: One study was not reporting results yet but in the rest of the sections complied with the checklist in 21 out of the 25 items. Two out of five of the trials achieved moderate score (21/37 and 20/37) and two trials achieved high scores (31/37 and 30/37). Conclusions: Although there are limited RCT's, that compare hip arthroscopy to other treatments for FAI, the results based the CONSORT checklist have been more than adequate indicating moderate to high compliancy.
Journal of ISAKOS, Jun 1, 2023
European Journal of Orthopaedic Surgery and Traumatology, Aug 13, 2021
Purpose Hip fractures are associated with functional decline and increased mortality. The aim of ... more Purpose Hip fractures are associated with functional decline and increased mortality. The aim of this study was to investigate the effect of zoledronic acid and high-dose vitamin D on function and mortality after hip fractures. Patients and methods Forty-five patients received zoledronic acid and high dose of vitamin D during hospitalization after fracture management. These patients were compared with a control group of 46 patients. Pre-and postoperative prospectively collected data including ASA score, Charlson comorbidity score, presence of dementia, Vitamin D, and the Barthel index were available. Final follow-up was performed after one year. Primary outcome was patients' function at final follow-up as measured with Barthel index score. Secondary outcomes included mortality, assessment of pain, and complications. Results Barthel index score at final follow-up was decreased in both groups. There was no significant difference in Barthel index between the two groups (15.5 ± 5.0 vs 15.8 ± 5.8, p = 0.850). However, the Barthel index in the control group decreased beyond the smallest detectable change (3 points). Mortality was statistically different between groups (8.8% vs 28.2%, p = 0.047). Complications and pain at final follow-up were not different between groups. Multivariate analysis revealed that preoperative Barthel index and Charlson comorbidity score independently affected function at final follow-up. Logistic regression analysis disclosed that not receiving active treatment and complications were associated with increased mortality. Conclusions Medical treatment after surgical management of hip fractures results in reduced mortality and lessens the functional decline associated with these fractures.
Revue de Chirurgie Orthopédique et Traumatologique
Orthopaedic Journal of Sports Medicine
Background: Long-term studies of patients after anterior cruciate ligament (ACL) reconstruction w... more Background: Long-term studies of patients after anterior cruciate ligament (ACL) reconstruction with or without concomitant meniscal tear treatment are limited. Purposes: To (1) report postoperative outcomes after anatomic ACL reconstruction with a hamstring autograft, (2) investigate how concomitant treatment of meniscal injury could affect these outcomes, and (3) evaluate the association between quality of life and activity levels at a minimum 10-year follow-up. Study Design: Cohort study; Level of evidence, 3. Methods: Patients treated with a unilateral, anatomic ACL reconstruction between 2005 and 2011 were investigated. The following patient-reported outcome measures (PROMs) were reported for the overall sample as well as a subsample of patients with meniscal injury: International Knee Documentation Committee Subjective Knee Form (IKDC-SKF), Knee injury and Osteoarthritis Outcome Score (KOOS), Lysholm knee score, Tegner activity scale, 5-level EQ-5D (EQ-5D-5L), and patient sati...
Journal of ISAKOS
Groin pain is a common symptom in athletes. The complex anatomy of the area and the various terms... more Groin pain is a common symptom in athletes. The complex anatomy of the area and the various terms used to describe the etiology behind groin pain have led to a confusing nomenclature. To solve this problem, three consensus statements have been already published in the literature: the Manchester Position Statement in 2014, the Doha agreement in 2015, and the Italian Consensus in 2016. However, when revisiting recent literature, it is evident that the use of non-anatomic terms remains common, and the diagnoses sports hernia, sportsman's hernia, sportsman's groin, Gilmore's groin, athletic pubalgia, and core muscle injury are still used by many authors. Why are they still in use although rejected? Are they considered synonyms, or they are used to describe different pathology? This current concepts review article aims to clarify the confusing terminology by examining to which anatomical structures authors refer when using each term, revisit the complex anatomy of the area, including the adductors, the flat and vertical abdominal muscles, the inguinal canal, and the adjacent nerve branches, and propose an anatomical approach, which will provide the basis for improved communication between healthcare professionals and evidence-based treatment decisions. Current concepts Groin pain is a common symptom in athletes, accompanied by a very complex nomenclature that makes diagnosis and treatment challenging. Despite the publication of three consensus statements, rejected terms are still widely used in the literature. Healthcare professionals dealing with groin pain should be careful when examining the literature, since the use of various terms in different ways may lead to false conclusions, thus making evidence-based practice difficult. Future perspectives Adopting results of all the available consensus statements is crucial for clarifying the terminology of groin pain. A specific anatomical diagnosis accompanying the classification proposed by the Doha agreement meeting, when possible, is strongly encouraged. A diagnostic approach and a treatment decision based on anatomy will facilitate evidence-based practice.
International Journal of Environmental Research and Public Health, Dec 27, 2022
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Microorganisms
Infection following anterior cruciate ligament (ACL) reconstruction can be one of the most debili... more Infection following anterior cruciate ligament (ACL) reconstruction can be one of the most debilitating complications following ACL reconstruction. Its reported incidence is around 1%. Utilization of vancomycin for presoaking the graft is considered an established method for infection prevention. The role of other agents, such as gentamycin needs further investigation. Staphylococci are the predominant causative pathogens, while particular attention should be paid to fungal infections due to their long-standing, occult process. Recent data demonstrate that hamstrings autograft may be at an elevated risk of being contaminated leading to subsequent septic arthritis. Diagnosis is set by clinical and laboratory findings and is usually confirmed by intraoperative cultures. Treatment varies, mainly depending on the intraoperative assessment. Satisfactory outcomes have been reported with both graft retaining and removal, and the decision is made upon the arthroscopic appearance of the graf...
Knee Surgery, Sports Traumatology, Arthroscopy, 2020
Purpose To evaluate the impact of local soaking of the autografts with vancomycin during anterior... more Purpose To evaluate the impact of local soaking of the autografts with vancomycin during anterior cruciate ligament (ACL) reconstruction on postoperative infection rates. Methods Between 2003 and 2014 (first study period), 1,242 patients underwent ACL reconstruction using autografts, without soaking them in vancomycin solution, while between 2014 and 2019 (second study period) all ACL autografts in 593 patients were soaked in a 5-mg/ml vancomycin solution, in a territory University Hospital. The same standard treatment of perioperative IV antibiotics was applied in both groups. Results Postoperative septic arthritis occurred in seven out of 1,242 patients (0.56%) during the first study period. Bone patellar tendon bone autograft was used in 311 (25%) patients, and hamstring tendon autograft was used in the rest 931 (75%) of the study population during this period. All infected cases were male and had a hamstrings graft implanted. There were no postoperative infections (0%) in 593 ACL reconstructions during the second study period. Bone patellar tendon bone autograft was used in 178 (30%) patients while hamstring tendon autograft was used in the rest 415 (70%) of the study population, during this period. Statistical analysis revealed a significantly reduced postoperative infection rate (p = 0.018) between the two reported periods, with the main impact referring to the use of hamstrings autograft (p = 0.031) for the first study period. Conclusions Septic arthritis following ACL reconstruction can be significantly reduced (or even eliminated) by soaking ACL autografts in a 5 mg/ml vancomycin solution. Of note, this strategy seems to be more effective in the setting of hamstring tendon autograft use, since the risk of postoperative knee infection is significantly higher when this type of graft is used.
European Journal of Orthopaedic Surgery & Traumatology, 2021
Purpose Hip fractures are associated with functional decline and increased mortality. The aim of ... more Purpose Hip fractures are associated with functional decline and increased mortality. The aim of this study was to investigate the effect of zoledronic acid and high-dose vitamin D on function and mortality after hip fractures. Patients and methods Forty-five patients received zoledronic acid and high dose of vitamin D during hospitalization after fracture management. These patients were compared with a control group of 46 patients. Pre-and postoperative prospectively collected data including ASA score, Charlson comorbidity score, presence of dementia, Vitamin D, and the Barthel index were available. Final follow-up was performed after one year. Primary outcome was patients' function at final follow-up as measured with Barthel index score. Secondary outcomes included mortality, assessment of pain, and complications. Results Barthel index score at final follow-up was decreased in both groups. There was no significant difference in Barthel index between the two groups (15.5 ± 5.0 vs 15.8 ± 5.8, p = 0.850). However, the Barthel index in the control group decreased beyond the smallest detectable change (3 points). Mortality was statistically different between groups (8.8% vs 28.2%, p = 0.047). Complications and pain at final follow-up were not different between groups. Multivariate analysis revealed that preoperative Barthel index and Charlson comorbidity score independently affected function at final follow-up. Logistic regression analysis disclosed that not receiving active treatment and complications were associated with increased mortality. Conclusions Medical treatment after surgical management of hip fractures results in reduced mortality and lessens the functional decline associated with these fractures.
2022 13th International Conference on Information, Intelligence, Systems & Applications (IISA)
Scientific Reports
Anterior cruciate ligament (ACL) deficient and reconstructed knees display altered biomechanics d... more Anterior cruciate ligament (ACL) deficient and reconstructed knees display altered biomechanics during gait. Identifying significant gait changes is important for understanding normal and ACL function and is typically performed by statistical approaches. This paper focuses on the development of an explainable machine learning (ML) empowered methodology to: (i) identify important gait kinematic, kinetic parameters and quantify their contribution in the diagnosis of ACL injury and (ii) investigate the differences in sagittal plane kinematics and kinetics of the gait cycle between ACL deficient, ACL reconstructed and healthy individuals. For this aim, an extensive experimental setup was designed in which three-dimensional ground reaction forces and sagittal plane kinematic as well as kinetic parameters were collected from 151 subjects. The effectiveness of the proposed methodology was evaluated using a comparative analysis with eight well-known classifiers. Support Vector Machines were...
Diagnostics, 2022
The improved treatment of knee injuries critically relies on having an accurate and cost-effectiv... more The improved treatment of knee injuries critically relies on having an accurate and cost-effective detection. In recent years, deep-learning-based approaches have monopolized knee injury detection in MRI studies. The aim of this paper is to present the findings of a systematic literature review of knee (anterior cruciate ligament, meniscus, and cartilage) injury detection papers using deep learning. The systematic review was carried out following the PRISMA guidelines on several databases, including PubMed, Cochrane Library, EMBASE, and Google Scholar. Appropriate metrics were chosen to interpret the results. The prediction accuracy of the deep-learning models for the identification of knee injuries ranged from 72.5–100%. Deep learning has the potential to act at par with human-level performance in decision-making tasks related to the MRI-based diagnosis of knee injuries. The limitations of the present deep-learning approaches include data imbalance, model generalizability across di...
Foot & Ankle Surgery: Techniques, Reports & Cases, 2022
Foot & Ankle Surgery: Techniques, Reports & Cases, 2022
MEDICINE AND HEALTHCARE REPORTS, 2020
Surgical Recovery [Working Title], 2019
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Papers by Georgios Chalatsis