Papers by Geofrey Musinguzi
Background: Persons with a systolic blood pressure (BP) of 120 to < 140 or diastolic BP of 80 ... more Background: Persons with a systolic blood pressure (BP) of 120 to < 140 or diastolic BP of 80 to < 90 mm hg are classified as having pre-hypertension. Pre-hypertension is associated with cardiovascular disease (CVD) risk factors, incident CVD and CVD mortality. Understanding determinants of pre-hypertension especially in low income countries is a pre-requisite for improved prevention and control. Methods: Data were analyzed for 4142 persons aged 18 years and older with BP measured in a community cross sectional survey in Uganda. The prevalence of pre-hypertension was estimated and a number of risk factors e.g. smoking, use of alcohol, overweight, obesity, physical activity, sex, age, marital status, place of residence, and consumption of vegetables and fruits were compared among different groups (normotension, pre-hypertension, and hypertension) using bivariate and multivariable logistic regression. Results: The age standardized prevalence of normal blood pressure was 37.6%, p...
International Journal of Environmental Research and Public Health
Background: Although Africa has long borne the brunt of the human immunodeficiency virus (HIV) ep... more Background: Although Africa has long borne the brunt of the human immunodeficiency virus (HIV) epidemic, until recently, the continent has been considered largely free of illicit drug use and injection drug use in particular. In Uganda, the number of people who use or inject drugs (PWUD and PWID, respectively) has increased, and PWID are a key population at high risk for human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection. However, harm reduction practices, including providing clean injection equipment and medication-assisted treatment (MAT), have only recently been piloted in the country. This project aims to integrate buprenorphine into a harm reduction drop-in center (DIC). Methods: The Consolidated Framework for Implementation Research was used to guide our preparations to integrate buprenorphine into existing practices at a harm reduction DIC. We conducted key informant interviews with members of a community advisory board and DIC staff to document this pro...
American Journal of Preventive Cardiology
International Journal of Environmental Research and Public Health, 2020
Background: Evidence is lacking on the effects of binge alcohol consumption on metabolic syndrome... more Background: Evidence is lacking on the effects of binge alcohol consumption on metabolic syndrome in the rural South African population. The purpose of this study was to investigate the association between binge drinking and components of metabolic syndrome (MetS) amongst Ellisras rural young adults aged 21 to 31 years who are part of the Ellisras Longitudinal Study. Methods: Logistic regression analysis was applied to a total of 624 participants (306 males and 318 females) aged 21 to 31 years who took part in the Ellisras Longitudinal Study (ELS). The model was adjusted for covariates, including smoking, age, and gender. Binge alcohol consumption was assessed using a standardised questionnaire that was validated for the Ellisras rural community. A standardised method of determining the components MetS was used after fasting blood samples were collected from all the participants. Results: Binge drinking remained significantly associated with low levels of high-density lipoprotein ch...
PLoS ONE, 2022
Introduction Healthy lifestyle practices including physical activity, healthy diets, non-smoking,... more Introduction Healthy lifestyle practices including physical activity, healthy diets, non-smoking, reduced alcohol consumption and stress reduction are important in the prevention of metabollic CVD risk factors such as hypertension, overweight and obesity, diabetes and hyperlipidaemia. Owing to current lifestyle changes, the increasing burden of CVD and importance of healthy behaviours, the need for strategies to increase uptake of healthy lifestyles among sub-Saharan African populations are apparent. This study explored the factors influencing uptake of healthy lifestyle practices among adults following implementation of a community CVD prevention programme. Methods This was a descriptive qualitative study conducted among purposively selected adults who had engaged in a community CVD prevention programme. Data were collected using in-depth interviews, which were audio recorded and transcribed verbatim. Study transcripts were read into NVIVO 12.6 software for coding and analysis guid...
Additional file 2. Consolidated criteria for reporting qualitative studies (COREQ): 32-item check... more Additional file 2. Consolidated criteria for reporting qualitative studies (COREQ): 32-item checklist.
Additional file 1. FGD Discussion Guide.
Additional file 6: Table S6. Parish and sex-specific prevalence of fruits and vegetables consumpt... more Additional file 6: Table S6. Parish and sex-specific prevalence of fruits and vegetables consumption -- A Cardiovascular Disease Risk Factor Atlas among adults in Mukono and Buikwe districts in Uganda – Analysis of Baseline data: The SPICES Project.
Additional file 2: Table S2. Parish and sex-specific prevalence Overweight/Obesity -- A Cardiovas... more Additional file 2: Table S2. Parish and sex-specific prevalence Overweight/Obesity -- A Cardiovascular Disease Risk Factor Atlas among adults in Mukono and Buikwe districts in Uganda – Analysis of Baseline data: The SPICES Project.
Additional file 7: Figure S1. Map of Muono and Buikwe district showing the distribution of variou... more Additional file 7: Figure S1. Map of Muono and Buikwe district showing the distribution of various Cardivacular Disease Risk Factors.
Additional file 1: Table S1. Parish and sex-specific prevalence hypertension -- A Cardiovascular ... more Additional file 1: Table S1. Parish and sex-specific prevalence hypertension -- A Cardiovascular Disease Risk Factor Atlas among adults in Mukono and Buikwe districts in Uganda – Analysis of Baseline data: The SPICES Project.
Additional file 2. Spices Project Participant's Questionnaire
Additional file 3. Completed COREQ checklist
Additional file 1. Focus group discussion guide for community health workers
Key Informant Interview Guide. This KII guide includes questions that were administered to health... more Key Informant Interview Guide. This KII guide includes questions that were administered to health providers as part of a large mixed-methods study aimed at exploring the barriers and opportunities for improving access to HIV services among MSM and FSWs in Uganda. Only questions that explored health providersâ experiences, perceptions and readiness to provide HIV services to MSM and FSWs were analyzed for this paper. (PDF 193 kb)
Additional file 2. Focus group discussion guide for community members
Africa is at a critical time undergoing demographic, epidemiological, political and socio-economi... more Africa is at a critical time undergoing demographic, epidemiological, political and socio-economic transitions and faced with repeated outbreaks of emerging and remerging diseases amidst other broader challenges of climate change, environmental degradation and pollution testing the resilience of its health systems and hindering progress to achieve health for all. Five years into the journey towards Sustainable Development Goals (SDGs), the continent – similar to the rest of the world – has been gripped with the Corona virus disease pandemic that has caused significant morbidity and mortality as well as severely disrupted health systems and the underlying socioeconomic determinants of health. One of the most significant SDG targets is the achievement of Universal Health Coverage (UHC) where all people have access to quality health services they need without inflicting a financial hardship on them. However, progress towards this target has been slow on the continent and requires rethi...
*<p>P-value generated using X<sup>2</sup> test.</p><p>Info on some ... more *<p>P-value generated using X<sup>2</sup> test.</p><p>Info on some variables was missing or not applicable.</p
JMIR Public Health and Surveillance, 2019
Background Key populations, including people who inject drugs (PWID), men who have sex with men (... more Background Key populations, including people who inject drugs (PWID), men who have sex with men (MSM), and female sex workers (FSW), are disproportionately affected by the HIV epidemic. Understanding the magnitude of, and informing the public health response to, the HIV epidemic among these populations requires accurate size estimates. However, low social visibility poses challenges to these efforts. Objective The objective of this study was to derive population size estimates of PWID, MSM, and FSW in Kampala using capture-recapture. Methods Between June and October 2017, unique objects were distributed to the PWID, MSM, and FSW populations in Kampala. PWID, MSM, and FSW were each sampled during 3 independent captures; unique objects were offered in captures 1 and 2. PWID, MSM, and FSW sampled during captures 2 and 3 were asked if they had received either or both of the distributed objects. All captures were completed 1 week apart. The numbers of PWID, MSM, and FSW receiving one or ...
PLoS ONE, 2014
Introduction: HIV epidemics are sustained and propagated by new cases of infection which result f... more Introduction: HIV epidemics are sustained and propagated by new cases of infection which result from transmission from infected persons to uninfected susceptible individuals. People living with HIV (PLHIV) play a critical role in prevention if they adopt safer sexual behaviors. This study estimated the prevalence of and factors associated with safer sexual behaviors among PLHIV seeking care from civil society organizations (CSOs). Methods: In a cross sectional study PLHIV were interviewed about their sexual practices, use of alcohol, HIV status of their regular sexual partners, desire for more children and about their socio-demographic characteristics. We calculated the proportion of PLHIV who abstained and consistently used condoms in the previous twelve months. Independent associations between safer sex and other variables were estimated using adjusted prevalence ratios (aPR) and their 95% confidence intervals (CI). Results: Of the 939 PLHIV, 54% (508) were either abstaining or using condoms consistently and 291 (31%) desired more children. The prevalence of consistent condom use among the sexually active was 41.3% (300/731). Consistent condom use was higher among PLHIV who: didn't use alcohol (aPR 1.30, CI 1.03-1.63); were educated about re-infection with a new strain of HIV (aPR 1.84, CI 1.08-3.12) and had regular sexual partner who was HIV negative (aPR 1.29, CI 1.05-1.57). Prevalence of abstinence was 22.2% (208/939). Abstinence increased with age from 9.4% among PLHIV ,25 years to 40.5% among those .50 years. Abstinence was extremely low (2.5%) among PLHIV who were married. Conclusions: Effective interventions that reduce alcohol consumption among PLHIV are needed to avert HIV transmission, prevent acquisition of new HIV strains and STIs. In addition, strategies are needed to address needs of PLHIV who desire more children.
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Papers by Geofrey Musinguzi