Papers by Branislava Gajic
Acta Medica Medianae, Jun 15, 2022
Srpski arhiv za celokupno lekarstvo
Introduction/Objective. The aim of this study was to evaluate psoriasis severity and psoriatic ar... more Introduction/Objective. The aim of this study was to evaluate psoriasis severity and psoriatic arthritis (PsA) as metabolic syndrome (MetS) and insulin resistance (IR) predictors in patients with chronic plaque psoriasis as well as to evaluate if psoriasis severity and PsA are independent predictors for IR regardless of the MetS presence. Methods. This prospective, observational descriptive cross-sectional study was conducted at Dermatovenereological Clinic of the University Clinical Centre of Vojvodina, and included a total of 105 psoriasis patients divided into three groups: group with mild psoriasis (Psoriasis Area Severity Index ? PASI score < 10), group with moderate to severe psoriasis (PASI ?10), and group with PsA diagnosed on the basis of the CASPAR criteria. Results. Percentage of patients who had MetS was higher in the group with the severe form of psoriasis (p < 0.05) as well as IR (p = 0.05). PsA was also more frequently associated with MetS (p = 0.05) and IR (p &...
Srpski arhiv za celokupno lekarstvo
Introduction/Aim. Psoriasis is a common, chronic, immune-mediated, inflammatory and proliferative... more Introduction/Aim. Psoriasis is a common, chronic, immune-mediated, inflammatory and proliferative skin disease in which both genetic and environmental influences have a role in its pathogenesis. The relationship between psoriasis and obesity is probably bidirectional. The aim of this study was to evaluate the association between psoriasis and obesity, whether a quantitative graduation of overweight using Body Mass Index (BMI) shows direct correlation with various clinical variants of psoriasis, disease duration and having positive family history of psoriasis. Methods. This prospective, observational descriptive cross-sectional study included 120 psoriatic patients who were referred to Clinic of Dermatovenereology at the University Clinical Centre of Vojvodina. Clinical variants of psoriasis were determined. Age, gender, duration of the disease, BMI and family history of psoriasis were measured and compared. Results. In total, 53.3% males and 46.7% females were included in this study...
Vojnosanitetski pregled
Background/Aim. The growing incidence of skin tumors requires an accurate diagnosis. Dermoscopy, ... more Background/Aim. The growing incidence of skin tumors requires an accurate diagnosis. Dermoscopy, especially in vivo, enhances the diagnosis of basal cell carcinoma (BCC). Total body skin examination (TBSE), a visual inspection of the patient?s total body surface, is considered a basic step in the dermatological exam, especially in skin cancer screening. However, TBSE is still a matter of debate regarding its expediency in a real clinical setting. The aim of this study was to analyze the diagnostic accuracy of BCC detected and treated by referred dermatologists. Methods. The retrospective analysis included a five-year period of BCC detection during TBSE by visual inspection and dermoscopy. We calculated sensitivity, specificity and positive predictive value for BCC using histopathological results as the correct diagnosis. Results. Out of 3,346 biopsied skin tumors, 49.58% were malignant and 50.42% benign. The most common malignant tumor was BCC, accounting for 84.09%. Localization of...
Srpski arhiv za celokupno lekarstvo, 2021
Introduction. Localized unilateral hyperhidrosis (LUH) is a rare disorder of unknown origin, with... more Introduction. Localized unilateral hyperhidrosis (LUH) is a rare disorder of unknown origin, with multiple possible triggering factors and unknown pathogenesis. Although there are cases of LUH of the face reported, this is the first to report isolated ipsilateral hyperhidrosis of the face after blunt force trauma. Case outline. A 54-year old Caucasian woman presented with facial LUH of five years? duration. Ipsilateral blunt trauma of the temple that preceded the condition for three months was identified as the most probable cause. For sharp demarcation, the Minor?s or starch?iodine test was performed, which revealed the presence and extent of the facial sweating on the left side of the face. Treatment with 20% aluminium chloride hexahydrate sol. (Retrargin sol.) was conducted with partial response. Conclusion. After ruling out underlying diseases as a cause of LUH, a prior trauma should be considered as a potential cause. The possible mechanism could be the lesion of sympathetic ch...
Hospital Pharmacology - International Multidisciplinary Journal, 2021
Introduction: Cutaneous larva migrans (CLM) is a syndrome, defined by clinical appearance of slow... more Introduction: Cutaneous larva migrans (CLM) is a syndrome, defined by clinical appearance of slowly migrating cutaneous eruption caused by inoculation with animal hookworms larvae in the skin. Despite the typical clinical presentation, CLM is frequently misdiagnosed due to its rarity in temperate climate urban communities. Case Report: We report a case of a 42-year old female, admitted to an outpatient clinic with eruption of multiple intense pruritic, erythematous, exudative papules and oval plaques, located predominately on the back. The patient claimed that skin lesions started three weeks before the examination, during her vacation in Thailand, and at first, was taught to be caused by a contact with jelly fish. Lesions were treated unsuccessfully with oral antihistamines and various topical corticosteroids, which lead to more questions regarding the differential diagnosis. Dermoscopical and histopathological findings were indicative of parasitic infection, most likely CLM. A thr...
Serbian Journal of Dermatology and Venereology, 2019
Acne keloidalis nuchae (AKN) / folliculitis keloidalis nuchae (FKN) is a chronic inflammatory con... more Acne keloidalis nuchae (AKN) / folliculitis keloidalis nuchae (FKN) is a chronic inflammatory condition which involves hair follicles localized predominantly in occipital scalp and posterior neck area leading to hypertrophic scarring alopecia. We present a 59-year-old factory worker, Caucasian male with a whitish alopecic oval plaque about 10 cm in diameter in the occipital region. The peripheral part of plaque was mildly inflammated, with groups of tufted terminal hairs, while the central part showed cicatricial alopecia and discrete non-adherent dry scales. Skin changes firstly occurred 6 years earlier, as itchy papules and pustules that sometimes healed with scarring. The applied relevant diagnostic and therapeutical measures are discussed in this report.
Serbian Journal of Dermatology and Venereology, 2017
Mammary Paget's disease is a rare intraepithelial carcinoma of the nipple/areola complex ofte... more Mammary Paget's disease is a rare intraepithelial carcinoma of the nipple/areola complex often associated with ductal breast carcinoma. We report a case of a 55-year-old female patient with a classical form of mammary Paget's disease associated ductal ipsilateral breast carcinoma. Dermoscopy of Paget's disease revealed a whitish-pink area with polymorphous vessels organized in irregular nests separated by pale streak-like structures, with peripheral light brown diffuse pigmentation. Dermoscopic features described in this case are in agreement with rare previous reports and may contribute to better differentiation of mammary Paget's disease from clinically similar lesions.
Vojnosanitetski pregled, 2017
Introduction. Acronym tick-borne lymphoadenoathy (TIBOLA (Dermacentor-borne necrosis erythema and... more Introduction. Acronym tick-borne lymphoadenoathy (TIBOLA (Dermacentor-borne necrosis erythema and lymphoadenopathy ? DEBONEL, scalp eschar associated with neck lymphoadenopathy ? SENLAT) comprises clinical diagnosis of tick-borne symptoms of cervical or occipital lymphadenopathy with inoculation eschar at the site of tick bite on scalp. Since the first description, it was proved to be associated with several infectious agents, most frequently Rickettsia slovaca, or less often other spotted fever group Rickettsiae (Rickettsia raoulti and Rickettsia rioja), and gained an emerging infectious disease status in Europe. Dermacentor ticks serve as vectors and possible natural reservoir. The course is in most cases benign and infection is limited. Doxicycline is the recommended initial treatment, both for adult and most cases in children. Case report. Two subjects who acquired the desease caused by tick bites in Vojvodina region of Serbia are presented. Both patients are females. A tick was...
Vojnosanitetski pregled, 2016
Introduction. Hydroxyurea (HU) is a cytostatic agent, frequently used for the treatment of myelop... more Introduction. Hydroxyurea (HU) is a cytostatic agent, frequently used for the treatment of myeloproliferative disorders, sickle cell anemia and severe forms of psoriasis. Cutaneous side effects occur in up to one third of patients taking hydroxyurea, with the most serious side effect being susceptibility to develop non-melanoma skin cancers. Case report. We report 3 patients using HU that have developed multiple skin malignancies on the head and neck region and dorsa of the hands, arranged according to the level of the overall squamous dysplasia expressed. Conclusion. A cumulative dose of hydroxyurea affects skin cancer promotion in concordance with other risk factors determining cumulative ultraviolet exposure (age of the patients, skin phototype, sun habits), but the exact influence of each of them and enrollment of other possible cofactors remains to be elucidated. We point out the importance of adequate skin cancer preventive and therapeutic approach to the patients treated with...
Vojnosanitetski pregled, 2014
Introduction. Erosive pustular dermatosis of the scalp (EPDS) is a rare disorder of unknown etiol... more Introduction. Erosive pustular dermatosis of the scalp (EPDS) is a rare disorder of unknown etiology that usually occurs in the elderly and is characterized by multiple pustules, erosions and crusts that appear on the scalp leading to scarring alopecia. The histopathology and laboratory tests are not specific which is the reason that EPDS is a frequently misdiagnosed condition. Case report. We presented two patients with EPDS. The first patient had the known history of local trauma, both patients had chronic recidivant process, classic clinical presentations, and nonspecific histological findings. Each patient had prompt therapeutical response to potent topical steroids. Conclusion. The diagnosis of EPDS can be made if a condition fulfills the following criteria: atrophic or actinic damaged skin, clinical association of erosions, pustules, scales and crusts, no specific histopathology, no infectious agent found responsible for the condition, and chronic course leading to scarring al...
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Papers by Branislava Gajic