Papers by Mohamed El Esawy
Journal of Cosmetic Dermatology, 2019
Male androgenetic alopecia (MAGA) is a noncicatricial patterned hair loss with the conversion of ... more Male androgenetic alopecia (MAGA) is a noncicatricial patterned hair loss with the conversion of terminal to vellus hair. 1 The hair integrity depends on an adequate and balanced nutritional intake, and unbalanced diet may result in excessive hair shedding. 2 The relations of nutritional deficiency with chronic telogen effluvium, female pattern hair loss, MAGA, and alopecia areata were studied. 3,4 Zinc has a functional role in hair follicle cycling (animal model), 5 a critical component in its morphogenesis, 6 potent dose-dependent immune-modulator of hair follicles, 7 regulate hair growth through hedgehog signaling as it is a catagen inhibitor. 8 Dermatological symptoms of zinc deficiency include nail dystrophy, acral and periorificial dermatitis, cheilitis, brittle hair, delayed wound healing, and skin superinfection. 4,9 The zinc deficiency effects may appear before serum levels decrease below normal. 10 Biotin is an essential water-soluble vitamin required as a cofactor for carboxylase enzymes. 3 Biotin deficiency can be either congenital or acquired secondary to increased raw egg consumption, 11 alcoholism, pregnancy, or other medications such as isotretinoin and
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Papers by Mohamed El Esawy