Papers by PROF DR BHOOPENDRA Singh
Toxicologie Analytique et Clinique
International Journal of Medical Toxicology & Legal Medicine, 2021
International Journal of Medical Toxicology & Legal Medicine, 2021
Medico-Legal Update, 2017
Indian journal of experimental biology, 1999
The importance of nutrition in protecting the living organism against the potentially lethal effe... more The importance of nutrition in protecting the living organism against the potentially lethal effects of reactive oxygen species and toxic environmental chemicals has recently been realized. This new perspective has prompted re-evaluation of the food constituents of human diet from the point of view of their nutritional adequacy, deficiency and toxicity. The biological antioxidant defense system is an integrated array of enzymes, antioxidants and free radical scavengers. These include glutathione reductase, glutathione-s-transferase, glutathione peroxidase, phospholipid hydroperoxide glutathione peroxidase, superoxide dismutase (SOD) and catalase, together with the antioxidant vitamins C, E and A. The individual components of this system get utilized in various physiological process and for chemoprotection and therefore require replenishment from the diet. Other components of the diet like carbohydrates, proteins and lipids are important for maintaining the levels of various enzymes ...
Journal of Family Medicine and Primary Care, 2020
Background and Aim: Road traffic injuries (RTIs) are a leading cause of mortality and morbidity g... more Background and Aim: Road traffic injuries (RTIs) are a leading cause of mortality and morbidity globally. This study aimed to assess the incidence and pattern of RTIs in the tribal population of Jharkhand. Methods and Materials: This prospective observational study was conducted for a period of 1 year (June 2018 to May 2019) at the Rajendra Institute of Medical Sciences, Ranchi, Jharkhand. A pretested semi-structured questionnaire was administered. A total of 1713 road traffic accident (RTA) victims belonging to tribal population were interviewed during the study period. Data were entered in a Microsoft Excel sheet and analyzed using Statistical Package for Social Sciences (SPSS) version 16. Results: There were 1258 (73.4%) males and 455 (26.6%) females. The majority (31.4%) of patients belonged to the age group of 21–30 years, followed by 19.2% in the age group of 31–40 years. The majority (52.13%) of RTAs involved a two-wheeler vehicle. Head injury was the most common type of injury (40.86%), followed by lower limb injury (26.68%). Common upper limb injuries were in the humerus and radius and ulna region. The majority of lower limb injuries involved tibia and femur. Common thoracic-abdomen injuries were soft tissue injury and lung contusion. Drunk driving (alcohol influence) was seen in 34.68% of cases of RTI. Conclusions: RTA is a major public health problem which needs to accelerate the efforts of road safety preventive measures. Road safety education should be promoted.
International Journal of Orthopaedics Sciences, 2017
Background: Distal humerus fracture is one of the commonest fractures among young adults and whic... more Background: Distal humerus fracture is one of the commonest fractures among young adults and which accounts for about 30% of all elbow fractures. The treatment of these fractures continues to the challenges for orthopedics despite of many advances in technique and implants. Different modalities like 1/3rd tubular plate, reconstruction plate, K wires, double tension band wiring, etc, have been tried. The new distal humerus locking compression plate (LCP) system allows angular stable fixation of these complex fractures with anatomically pre-shaped plates. Aims: Aim of this study is to assess the benefits of using locking compression plate (LCP) in the management of distal humerus fractures clinically and as well as functionally. Materials and Methods: A prospective study of 30 adult patients with closed distal humerus fractures were treated by locking compression plate in the department of Orthopaedics, RIMS, Ranchi, between June 2014 to Sep 2015. Variables of each patient were recorded and analysed with respect to age, sex, fracture type, mode of injury, limb involvement, associated injuries, timing and duration of operation, duration of hospital stay, follow up, complications and final outcomes. These patients were followed up at different intervals i.e. at 3 weeks for first 3 months, then at 6-weeks interval for next 6 months and then at 3-month interval. Results: The average age was 38.5 years and majority patients were men (60%). The right humerus was involved in majority (70%) of patients. The complete union was achieved in all patients which was confirmed by radiographically. Average time interval between admission of patients and surgery was 7.8 days (range 4-13 days). The average operative time was 82 minutes (range 70-100 min). All the fractures as well as the olecranon osteotomies united at 12-18 weeks (average 13.80 weeks). There were no any case of primary malposition or secondary dislocation was observed. Using the Mayo elbow performance score, the majority (53.33%) of patients were graded as excellent. There was no any patient reported with deep infection, implant failure, non-union of fracture site or olecranon osteotomy site. There were only three patients those reported superficial wound infection, which was treated with antiseptic dressing and antibiotics. Transient ulnar nerve palsy developed in only 2 (6.66%) cases and both were recovered with conservative treatment. Conclusion: Findings can be concluding that the treatment of distal humerus fractures is a challenging task. Anatomically pre-shaped distal humeral locking compression plate system facilitates operative reduction and stabilization of the fracture and may allow with good range of motion, and flexion and extension force.
International Journal of Orthopaedics Sciences, 2016
Background: Supracondylar fractures of femur present a huge surgical challenge. The introduction ... more Background: Supracondylar fractures of femur present a huge surgical challenge. The introduction of locking compression plate (LCP) has brought a remarkable change in the management of supracondylar fractures of distal femur. Aim: The aim of this study was to evaluate the rate of union, functional outcome and complications of these fractures treated with open reduction and internal fixation with a locking compression plate. Materials and method: The present study was conducted in the Department of Orthopedics, RIMS, Ranchi during June 2014 to December 2015. A 40 adult patients with closed supracondylar fractures of distal femur (Muller Type-A) and treated by locking compression plate were included in this study. Variables of each patients were recorded and analyzed with respect to age, sex, fracture type, mode of injury, limb involvement, associated injuries, timing and duration of operation, duration of hospital stay in days, follow up, complications and final outcomes. Patients were evaluated both clinically as well as radiologically at 6 weeks interval for first 6 months, then every 3 months for next 6 months and then at every 6 months. Results: The mean age of patients was 27.50 yrs. Out of 40 patients, 26 (65%) were male and 14 (35%) were female. The right femur was involved in 22 (55%) patients, and left in 16 (40%) patients while both femur was involved in only 2 (5%) patients. Clinical union was seen at 12.65 weeks (10-30 weeks) in all cases. Radiologically bridging callus was seen at 12th post-operative week and complete radiological union at a mean time of 25.73 weeks (20-40 weeks). 34 (85%) patients had excellent, 4 (10%) patients had good outcome and 2 (5%) patients had failure in the final result. Conclusion: Locking compression plate fixation is a safe procedure for supracondylar fractures of distal femur with an excellent functional outcome, early clinical and radiological union and it can be done on a routine basis with a minimum risk of complications.
International Journal of Medical Toxicology & Legal Medicine, 2021
International Journal of Medical Toxicology & Legal Medicine, 2021
Indian journal of occupational and environmental medicine, 2009
A simple and rapid method is described for the estimation of some organophosphorus insecticides i... more A simple and rapid method is described for the estimation of some organophosphorus insecticides in the serum of occupationally exposed persons. The compounds are extracted with a mixture of acetone and diethyl ether (1:1 v/v) in acidic medium and the extraction residue is analyzed by gas chromatography with nitrogen phosphorus detection method. Linearity was acceptable over concentrations from 0.25 to 4.0 mug/mL. The method percentile recovery for the six different organophosphorus insecticides was 86.3% for phorate, 78.3% for dimethoate, 82.3% for malathion, 79.4% for chlorpyrifos, 80.2% for diazinon, and 68.5% for ethion at the mug/mL level. Serum samples of nine workers who had been occupationally exposed to malathion in an insecticide manufacturing factory, were analyzed and malathion was found at low levels in all the samples.
2012 IEEE International Conference on Power Electronics, Drives and Energy Systems (PEDES), 2012
This paper presents miniature size dual outputs DC-DC converter for military applications. Propos... more This paper presents miniature size dual outputs DC-DC converter for military applications. Proposed converter is designed using self-resonant reset forward converter topology followed by fixed high switching frequency (>250 KHz) with UCC28C45 as a PWM controller. The self resonant reset method eliminates power loss in the reset circuit, thus simplifying the circuitry and increasing efficiency. Isolation in control loop is provided by optocoupler as it does an excellent job of isolation, minimizing circuit complexity and reducing cost. The proposed topology is demonstrated with an experimental prototype that delivers dual outputs 5V/3A, 3.3V/4A from an 18-36 V input voltage range with efficiency better than 75%. Meeting Cross regulation in multi-output converter is a very challenging task. The other challenging task was meeting the transient response as per MIL-STD-1275A which requires an application of 100V for 50msec and also meeting the transient response as per MIL-STD-704A, MIL-STD-704D (80V for 100msec) without over designing the converter for such a high voltage. This paper provides a technique to meet these challenges in the MIL-Grade DC-DC Converter. This converter has an inbuilt EMI/EMC filter and is realized in a very small size of 50 mm × 50 mm × 12.5 mm aluminum package.
Global journal for research analysis, 2017
Background : Suicidal behaviour is any deliberate action that has potentially life-threatening co... more Background : Suicidal behaviour is any deliberate action that has potentially life-threatening consequences, such as taking a drug overdose, deliberately consuming poison, hanging, drowning, burn etc. The aim of this study was to illustrate the epidemiological profile of complete suicidal poisoning cases autopsied at Department of Forensic Medicine and Toxicology, Rajendra Institute of Medical Sciences, Ranchi, India. Methods: All cases autopsied at autopsy centre of department of forensic medicine and toxicology between April 2013 to October 2014 evaluated. Data obtained from the Information regarding the socio-demographic, mode of suicides, time of incidence, place of incidence, occupation, etc were gathered from the police papers like inquest report, dead body challan etc, and through detailed interviews of the relatives, neighbours, friends, and police officials accompanying the dead bodies. Results: Total 3492 cases were autopsied, out of which only 180 cases were due to acute ...
Journal of Family Medicine and Primary Care
Organophosphorus compounds are absorbed by any route including intramuscular injection. Pyrethroi... more Organophosphorus compounds are absorbed by any route including intramuscular injection. Pyrethroid compounds are less toxic for human but in combination with organophosphates, its toxic effect potentiates due to inhibition of its metabolism. In this case report, a 40-year-old female patient presented with acute onset of pain abdomen, recurrent vomiting, and excessive salivation followed by altered mental status, on evaluation her clinical findings were suggestive of organophosphorus poisoning. Her treatment was started with injection atropine, anti-emetics, and adequate parenteral rehydration. After regaining consciousness, the patient confessed that she had taken herself intramuscular injection of pesticide which contained 3% cypermethrine plus 20% quinolphos. It was further confirmed by a very low level of plasma cholinesterase level. Intramuscular injection acted as a depot that leads to prolong intoxication and in the due course of illness, she also developed delayed onset intermediate syndrome that was managed appropriately.
Indian Journal of Anatomy
Indian Journal of Forensic Medicine and Pathology
Uploads
Papers by PROF DR BHOOPENDRA Singh