Papers by DR.MD.MURSHIDUR RAHMAN KHAN
Journal of Shaheed Suhrawardy Medical College, Sep 8, 2020
Objective: This study was undertaken with the aim to detect extent of drugs use in elderly patien... more Objective: This study was undertaken with the aim to detect extent of drugs use in elderly patients at Cardiology outpatient department of a tertiary care teaching hospital and to evaluate inappropriate prescribing with the help of Beers Criteria 2015. Material and Methods: The study was carried out at Cardiology outpatient department of Shaheed Suhrawardy medical college hospital, Dhaka, Bangladesh from May 2018 to April 2019. Total 2351 Geriatric patients were included during the study period of 12 months. The data was collected in a prescribed data form which included the patient's details and the prescriptions. Results: The result revealed that 11.96% of total drugs were prescribed inappropriate manner and 27.26% of total patients received at least one inappropriate drug prescription. Administration of a drug which should be avoided in elderly forms a common category of inappropriate drug use. Antihypertensive, Anti-platelets, Anti-diabetics, Antibiotics and Sedatives/ Hypnotics were the most common drug groups prescribed in inappropriate manner. Conclusion: This study shows high prevalence of inappropriate use of drugs in geriatric patients which needs attention to improve the situation.
Journal of Shaheed Suhrawardy Medical College, Jul 5, 2018
Background: Irrational drug prescribing is a common practice globally; it results in increased mo... more Background: Irrational drug prescribing is a common practice globally; it results in increased morbidity, mortality & economic burden on society. Drug utilization studies are an important tool to promote rational prescribing. Aims & Objective: To study on drug prescribing pattern in hypertensive patients. Materials and Methods: A drug utilization study was conducted in hypertensive patients by the department of cardiology in OPD at Shaheed Suhrawardy Medical college hospital for 6 months. 645 prescriptions were evaluated for prescribing pattern by using WHO drug use indicators. Results: 645 prescriptions were analyzed. A total of 1828 drugs were prescribed. 697 (38.13%) antihypertensive, 243 (13.30%) anti diabetics, 174 (9.52%) non-steroidal anti-inflammatory drugs (NSAIDs), 154 (8.44%) statins, 114 (6.24%) thyroid hormone, 54 (2.95%) anti-anxiety/ antidepressants and 392(21.44%) miscellaneous drugs were prescribed. 697 antihypertensive drugs were prescribed. 234 (33.57%) angiotensin receptor blockers (ARBs), 117 (16.79%) angiotensin converting enzyme (ACE) inhibitors, 95 (13.63%) Beta blockers, 83 (11.91%) Calcium channel blockers 168 (24.10%) Fixed dose combinations (FDCs) of antihypertensive were included. 2.83 drugs were prescribed per prescription. 225 (32.28%) antihypertensive were prescribed from essential medicine list. Conclusion: Most commonly prescribed drugs were ARBs and ACE inhibitors. Rational prescribing requires consideration to dose and duration and interaction with other medications.
Global heart, Mar 1, 2014
Introduction: The adverse impact of genetic aortopathies of the non-Marfan spectrum is increasing... more Introduction: The adverse impact of genetic aortopathies of the non-Marfan spectrum is increasingly recognized. Surgical intervention with aortic root replacement is advocated to prevent fatal dissection, but residual risk remains for dissection of other aortic segments. Objectives: To characterize the risk of recurrent adverse aortic events after initial surgical intervention in patients with Marfan and non-Marfan aortopathy. Methods: Prospective enrolment of all patients with genetic aortopathy in dedicated clinic registry from 1990-2012, with documentation of all adverse events, including surgery, dissection and death. Results: There were 273 Marfan and 365 non-Marfan patients enrolled with mean followup of 12.2 years and 5.9 years respectively. There were 139 first events in the Marfan group (26 fatal) followed by 53 second events (19 fatal) at 6.9 AE 6.2 years after first event and 21 third events (9 fatal) at 5.1 AE 4.4 years after second event. In the non-Marfan group there were 269 first events (85 fatal) with 48 second events (24 fatal) at 6.0 AE 6.7 years after first event and 11 third events (5 fatal) at 4.5 AE 4.8 years after second event. Conclusion: Both Marfan and non-Marfan aortopathy have high adverse event rates, although first events occur later in non-Marfan aortopathy. Both groups have significant number of recurrent events relatively soon after the first event.
Global Heart, 2014
Introduction: The adverse impact of genetic aortopathies of the non-Marfan spectrum is increasing... more Introduction: The adverse impact of genetic aortopathies of the non-Marfan spectrum is increasingly recognized. Surgical intervention with aortic root replacement is advocated to prevent fatal dissection, but residual risk remains for dissection of other aortic segments. Objectives: To characterize the risk of recurrent adverse aortic events after initial surgical intervention in patients with Marfan and non-Marfan aortopathy. Methods: Prospective enrolment of all patients with genetic aortopathy in dedicated clinic registry from 1990-2012, with documentation of all adverse events, including surgery, dissection and death. Results: There were 273 Marfan and 365 non-Marfan patients enrolled with mean followup of 12.2 years and 5.9 years respectively. There were 139 first events in the Marfan group (26 fatal) followed by 53 second events (19 fatal) at 6.9 AE 6.2 years after first event and 21 third events (9 fatal) at 5.1 AE 4.4 years after second event. In the non-Marfan group there were 269 first events (85 fatal) with 48 second events (24 fatal) at 6.0 AE 6.7 years after first event and 11 third events (5 fatal) at 4.5 AE 4.8 years after second event. Conclusion: Both Marfan and non-Marfan aortopathy have high adverse event rates, although first events occur later in non-Marfan aortopathy. Both groups have significant number of recurrent events relatively soon after the first event.
Journal of Shaheed Suhrawardy Medical College, 2018
Background: Chest pain or discomfort caused by acute coronary syndrome (ACS) or angina has a pote... more Background: Chest pain or discomfort caused by acute coronary syndrome (ACS) or angina has a potentially poor prognosis, emphasizing the importance of prompt and accurate diagnosis. To evaluate a clinic set up specifically to assess patients with recent onset chest pain, particularly those presenting with a normal resting electrocargram.Method: The cross-sectional study was carried out from September 2016 to August 2017 in cardiology department of Shaheed Suhrawardy Medical College hospital, Sher-E-Bangla Nagar, Dhaka. Total 1000 consecutive patients with recent onset chest pain were evaluated within 24 hours of general practitioner referral, to find out the clinical diagnosis and management.Results: Total 1000 patients (535 men and 465women, mean age 51.5±11.4 years with range from 32 to 70 years) were assessed over 12 months. Most of the patients 844 (84.4%) had symptoms in duration of ≤30 days. Majority 433 (43.3%) patients had peptic ulcer disease (PUD), 317 (31.7%) patients had...
Journal of Shaheed Suhrawardy Medical College, 2018
Background: Irrational drug prescribing is a common practice globally; it results in increased mo... more Background: Irrational drug prescribing is a common practice globally; it results in increased morbidity, mortality & economic burden on society. Drug utilization studies are an important tool to promote rational prescribing.Aims & Objective: To study on drug prescribing pattern in hypertensive patients.Materials and Methods: A drug utilization study was conducted in hypertensive patients by the department of cardiology in OPD at Shaheed Suhrawardy Medical college hospital for 6 months. 645 prescriptions were evaluated for prescribing pattern by using WHO drug use indicators.Results: 645 prescriptions were analyzed. A total of 1828 drugs were prescribed. 697 (38.13%) antihypertensive, 243 (13.30%) anti diabetics, 174 (9.52%) non-steroidal anti-inflammatory drugs (NSAIDs), 154 (8.44%) statins, 114 (6.24%) thyroid hormone, 54 (2.95%) anti-anxiety/ antidepressants and 392(21.44%) miscellaneous drugs were prescribed. 697 antihypertensive drugs were prescribed. 234 (33.57%) angiotensin r...
Bangladesh Heart Journal, 2018
Objective: The objective of the present study was to provide recent population-based information ... more Objective: The objective of the present study was to provide recent population-based information on use of cardiovascular drugs in outpatients in a tertiary care hospital of Dhaka, Bangladesh. Methods: A prospective study of cardiovascular prescriptions of Outpatient Department of Department of Cardiology of Shaheed Suhrawardy Medical college hospital Dhaka, Bangladesh was carried out. A total of 215 prescriptions were collected for the study in Shaheed Suhrawardy Medical College Hospital Dhaka, Bangladesh from July 2015 to June 2016. The prescriptions were evaluated for rationality based on WHO model list of essential medicines. The prescriptions were critically analyzed using predetermined parameters.
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Papers by DR.MD.MURSHIDUR RAHMAN KHAN