Papers by Christoph Lischer
Anatomia, Histologia, Embryologia, Dec 31, 2023
Iranian Journal of Veterinary Surgery, Dec 1, 2016
Objective-The aim of this study was to evaluate the analgesic efficacy of intra-articular adminis... more Objective-The aim of this study was to evaluate the analgesic efficacy of intra-articular administration of tramadol in horses following arthroscopic surgery. Design-Experimental study. Animals-Ten Warmblood horses Procedures-Horses underwent arthroscopic surgery of the tarsocrural joint (TCJ) (8 horses) and metacarpo-metatarsophalangeal joint (MCPJ/MTPJ) (2 horses). Intra-articular tramadol (2 mg/kg) or saline was administered in randomly selected horses (5 in each group; 4x TCJ and 1x MCPJ/MTPJ) under general anesthesia prior to recovery. After the horses were fully recovered and had returned to the stable two observers, blinded to the treatment scored pain independently at 1, 2, 3, 4, 6, 8, 12 and 24 hours based on a composite measure pain scale (CMPS). Results-Significant difference in pain score (P < 0.001) was observed at any individual time-point between the two groups, except at 24 hours post treatment. A significant lower pain score was detected in tramadol treated group (P < 0.001), up to the twelfth hour after treatment. No significant difference was seen between various times in the saline group (P = 0.09). Conclusion and Clinical Relevance-Analgesic efficacy of intra-articular tramadol administration was demonstrated by significantly reduced pain scores following arthroscopic surgery in horses. This observation might be useful as basis for a multimodal analgesic protocol; however, more detailed studies are warranted.
Tierärztliche Praxis. Ausgabe Grosstiere, Nutztiere, 2003
Bei 24 Kuhen mit leichtgradigen Rusterholz-Sohlenge-schwuren wurde unter kontrollierten Bedingung... more Bei 24 Kuhen mit leichtgradigen Rusterholz-Sohlenge-schwuren wurde unter kontrollierten Bedingungen uber ei-nen Zeitraum von 50 Tagen der Heilungsverlauf uberpruft. Wahrend der Heilungsphase kam es bei 14 Tieren zu einer mikroskopisch sichtbaren Verbesserung der Hornstruktur (Gruppe A). Bei 10 Tieren konnte keine Verbesserung und zum Teil sogar eine Verschlechterung der Hornqualitat nachgewiesen werden (Gruppe B). Die Resultate der blut-chemischen Untersuchungen am Tag 0, 10, 20, 30, 40 und 50 wurden zwischen Gruppe A und B verglichen. Die durchschnittlichen Serumenzymaktivitaten der GLDH, ALT, AP, γ -GT und LDH lagen bei den Kuhen der Gruppe B zu jedem Messpunkt hoher als bei den Tieren der Gruppe A. Bei der AP und der GLDH war der Unterschied signifikant. Die Tiere mit einer Verschlechterung der Hornqualitat (Gruppe B) zeigten durchschnittlich signifikant niedrigere Vitamin-A-Konzentrationen als diejenigen mit einer Verbes-serung (Gruppe A). Die Ergebnisse bestatigen den bekann-ten Einfluss von Vitamin A auf die Wundheilung. Der unter-schiedliche Verlauf der zur Diagnose von Parenchymscha-den der Leber verwendeten Enzyme GLDH, ALT, AP, γ -GT und LDH weist darauf hin, dass eine subklinische Ein-schrankung der Leberfunktion bei Kuhen zu einer Beein-trachtigung der Heilung von Sohlengeschwuren beitragen kann.
Veterinary Surgery, Oct 30, 2019
Objective: To describe and evaluate an alternative technique for tenoscopic resection of the mani... more Objective: To describe and evaluate an alternative technique for tenoscopic resection of the manica flexoria (MF). Study design: Descriptive study. Sample population: Equine cadaver forelimbs and hind limbs (n = 36). Methods: Three surgeons varying in experience resected the MF in 12 limbs. The procedure was divided into six steps, including resection of the lateral/medial borders of the MF with a hook knife and resection of the proximal border with a micro scalpel. Outcomes compared between surgeons included completeness of resection, appearance of the margins of resection, appearance of the resected MF, collateral damage, and time required for resection. Results: The MF was successfully resected in all specimens, with a median time of 14 minutes 54 seconds (range, 6 minutes 42 seconds to 43 minutes 33 seconds). Nineteen of 36 MF were categorized as symmetric, 11 of 36 MF were categorized as mildly asymmetrical, and six of 36 MF had unequal borders. No differences were detected between surgeons regarding the appearance of the MF and number of iatrogenic lesions. Five lesions were considered potentially clinically relevant; three were caused by the arthroscope in the scutum (1) and the deep digital flexor tendon (DDFT; 2), and two consisted of DDFT damage caused by the microscalpel. Conclusion: The MF was successfully and symmetrically resected with minimal damage to adjacent structures by surgeons with varying levels of experience. Clinical significance: The results of this study provide evidence to justify further evaluation of the technique described here in live horses with rupture of the MF.
Equine Veterinary Education, Feb 1, 2009
PubMed, Feb 28, 2001
Sole ulcers are the most frequently encountered lesion in lame cattle. They are of growing concer... more Sole ulcers are the most frequently encountered lesion in lame cattle. They are of growing concern to the dairy industry since the incidence of ulcers is increasing. Ulcers cause financial losses, the animal's wellbeing is disturbed to a high degree and they harm the image of the industry in general. Biomechanic factors and laminitis are of particular significance in the pathogenesis of the sole ulcer. The development of sole contusions and ulcers is assumed to occur in 3 phases (Sinking theory). In the first phase there is a general disturbance in the vascular system of the corium. The second phase follows when the structures that suspend the claw bone within the horn shoe give way. The locus minoris resistentiae has yet to be identified. The claw bone sinks and causes various lesions when it pinches the underlying sole or heel corium. The third phase begins when haemorrhages become visible on the horn surface of the sole or when the sole ulcerates; socalled third phase lesions. The relationship between the development of sole ulcers and anatomical structures such as the claw bone's tuberculum flexorium or the fat bodies under the bone are unclear. Epidemiological studies have shown that sole ulcers have a high rate of recurrence. The healing processes and the factors that influence them have hitherto not been studied.
PubMed, Dec 7, 2002
The mural suspensory apparatus of third phalanx and its supportive heel cushion were examined in ... more The mural suspensory apparatus of third phalanx and its supportive heel cushion were examined in 19 cows with an ulcer at the 'typical' site (Rusterholz ulcer) to gain information on the pathogenesis of sole and heel ulcers. The claws of 17 healthy controls were used for comparison. The left hind claws, frozen at -20 degrees C, were sectioned in one longitudinal and four transverse planes with a band saw. The thickness of the subcutaneous tissue, the corium and the extent of displacement of the third phalanx were measured at defined sites on these sections. In addition, the suspensory apparatus, the tissue layer connecting the third phalanx to the dorsal wall of the horn capsule, was examined histologically. There was a direct relationship between the displacement of the third phalanx and ulceration of the sole or heel; in all the ulcerated claws the third phalanx had dropped and the corium and the subcutis under the bone were thinner than in the controls. The supportive cushions of the cows with ulcers contained less fat tissue. There was no histological evidence of damage to the epidermis or the corioepidermal junction in the ulcerated claws nor were the lamellae elongated. Similarly, there were no morphological changes in the connective tissue layer, the submural dermis.
Equine Veterinary Journal, Jul 13, 2022
Wageningen Academic Publishers eBooks, 2006
Veterinary Surgery, Nov 21, 2022
Veterinary Record, Mar 1, 1997
A four months pregnant, four‐year‐old Brown Swiss cow with mandibular fractures of the right hori... more A four months pregnant, four‐year‐old Brown Swiss cow with mandibular fractures of the right horizontal ramus and the symphysis was treated surgically with a new pinless external fixator. Healing was complicated by the sequestration of bone at the fracture site. After the sequestrum had been removed a radiographic examination revealed that the fracture had healed completely.
Equine Veterinary Journal, Jan 21, 2022
Background: Dynamic computed tomography (CT) imaging has been introduced in human orthopaedics an... more Background: Dynamic computed tomography (CT) imaging has been introduced in human orthopaedics and is continuing to gain popularity. With dynamic CT, video sequences of anatomical structures can be evaluated in motion. Objectives: To investigate the feasibility of dynamic CT for diagnostic imaging of the equine cervical articular process joints (APJs) and to give a detailed description of the APJ movement pattern. Study design: Descriptive cadaver imaging. Methods: Cervical specimens of twelve Warmblood horses were included. A custommade motorised testing device was used to position and manipulate the neck specimens and perform dynamic 2D and 3D CT imaging. Images were obtained with a 320-detector-row CT scanner with a 160 mm wide-area (2D) solid-state detector design that allows image acquisition of a volumetric axial length of 160 mm without moving the CT couch. Dynamic videos were acquired and divided into four phases of movement. Three blinded observers used a subjective scale of 1 (excellent) to 4 (poor) to grade the overall image quality in each phases of motion cycle. Results: With an overall median score of 1 the image quality, a significantly lower score was observed in the dynamic 3D videos over the four phases by the three observers compared with the 2D videos for both flexion (3D 95% CI: 1-2 and 2D 95% CI: 1-3; P = .007) and extension movement (3D 95% CI: 1-2 and 2D 95% CI: 1-3; P = .008). Median Translational displacement of the APJ surface was significantly greater in flexion than in extension movement (P = .002). Main limitations: The small number of specimens included. Excision of spines and removal of musculature. Conclusions: The study is a first step in the investigation of the potential of dynamic 3D CT in veterinary medicine, a technique that has only begun to be explored and leaves much room for refinement prior to its introduction in routine practice. CT with This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Uploads
Papers by Christoph Lischer