The goal of this article is to summarize current data on computed tomography (CT) and magnetic re... more The goal of this article is to summarize current data on computed tomography (CT) and magnetic resonance (MR) in the diagnosis of acute pulmonary embolism (PE) in relation to the radionuclide ventilation perfusion scan. It is important for the nuclear medicine, CT, and MR communities to develop a shared approach to this disorder. Triage using chest radiographs appears to be a practical method for enhancing both nuclear medicine and CT/MR performance. The realization that there is no clinically available gold standard for the diagnosis of PE suggests that the imaging community should replace impractical and
Rationale and Objectives. To compare the effectiveness of a new computational scheme for pulmonar... more Rationale and Objectives. To compare the effectiveness of a new computational scheme for pulmonary nodule detection in computed tomography images against human observers. Materials and Methods. The study involved evaluation of 81 potential nodules by four radiologists. Each radiologist separately evaluated the potential nodules and provided a confidence level for the presence of pulmonary nodules. Their performance was compared with that of the new computational scheme by mixture distribution analysis. Results. Mixture distribution analysis of the results of the four radiologists demonstrated a relative proportion agreement of 0.84. The kappa statistic was used to compare the agreement of the computational scheme with the results of the four radiologists. A kappa value of .65 (se ϭ .11) was shown to be significantly different from chance (P ϭ .99). Conclusion. The new computational scheme correlates well with the radiologists' subjective rankings of pulmonary nodules on computed tomography scans and may prove a useful tool in the evaluation of algorithms for the screening and diagnosis of lung cancer.
The goal of this article is to summarize current data on computed tomography (CT) and magnetic re... more The goal of this article is to summarize current data on computed tomography (CT) and magnetic resonance (MR) in the diagnosis of acute pulmonary embolism (PE) in relation to the radionuclide ventilation perfusion scan. It is important for the nuclear medicine, CT, and MR communities to develop a shared approach to this disorder. Triage using chest radiographs appears to be a practical method for enhancing both nuclear medicine and CT/MR performance. The realization that there is no clinically available gold standard for the diagnosis of PE suggests that the imaging community should replace impractical and
Rationale and Objectives. To compare the effectiveness of a new computational scheme for pulmonar... more Rationale and Objectives. To compare the effectiveness of a new computational scheme for pulmonary nodule detection in computed tomography images against human observers. Materials and Methods. The study involved evaluation of 81 potential nodules by four radiologists. Each radiologist separately evaluated the potential nodules and provided a confidence level for the presence of pulmonary nodules. Their performance was compared with that of the new computational scheme by mixture distribution analysis. Results. Mixture distribution analysis of the results of the four radiologists demonstrated a relative proportion agreement of 0.84. The kappa statistic was used to compare the agreement of the computational scheme with the results of the four radiologists. A kappa value of .65 (se ϭ .11) was shown to be significantly different from chance (P ϭ .99). Conclusion. The new computational scheme correlates well with the radiologists' subjective rankings of pulmonary nodules on computed tomography scans and may prove a useful tool in the evaluation of algorithms for the screening and diagnosis of lung cancer.
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