Nigella sativa (NS) (Ranunculaceae family) is generally utilized as a therapeutic plant all over ... more Nigella sativa (NS) (Ranunculaceae family) is generally utilized as a therapeutic plant all over the world. The seeds of the plant have a long history of use in different frameworks of medicines and food. N. sativa seeds reveal a broad spectrum of pharmacological activities including immunopotentiation and antihistaminic, antiseptic, antiallergic, anti-hypertensive, anti-inflammatory, and antimicrobial activities. It is known as a source of thymoquinone (TQ), thymohydroquinone, dithymoquinone, p-cymene, carvacrol, 4-terpineol, t-anethol, sesquiterpene longifolene, nigellicimine and nigellicimine-N-oxide, α-pinene and thymol etc. Additionally, this is uncovered that the majority of therapeutic properties of this plant are due to the presence of thymoquinone which is a major bioactive component of the essential oil. The incalculable medicinal properties and therapeutic uses of N. sativa prove its importance as a valuable medicinal plant. The aim of this review is to summarize some important pharmacological studies and phytochemical investigations on N. sativa and isolated principles which can be investigated further to get novel molecules in the search of novel herbal drugs.
Journal of the Turkish Chemical Society, Section A: Chemistry, May 15, 2019
This study has focused on Morus alba, which is grown in Turkey mostly for the production of fruit... more This study has focused on Morus alba, which is grown in Turkey mostly for the production of fruit. M. alba seeds' analysis results showed that oil, protein, ash, ash insoluble in hydrochloric acid, and total carbohydrate were, 21.33±0.58 g, 21.58±0.13 g, 3.99±0.13 g, 0.9±0.00 g, 54.76±2.42 g for 100 g of sample respectively; the main minerals were calcium, phosphorus, and potassium. Dominating fatty acids were linoleic acid (80.56±0.22%), palmitic acid (7.96±0.06%), oleic acid (7.11±0.05%). The primary volatiles were l-limonene, 2,2-dimethyldecane, and hexanal. Sterol components were found as beta-sitosterol>delta-5-avenasterol>campesterol>cholestenol and the total sterols' amount was 5501.49±44.26 mg/kg. δ-tocopherol, γ-tocopherol, β-tocopherol, α-tocopherol, total phenolic content, the radical scavenging activity were 257.67±4.51 mg/kg, 18.23±0.11 mg/kg, 6.71±0.13 mg/kg, 3.23±0.06 mg/kg, 137.1±0.36 mgGAE/100 g oil, 19.9±0.46% respectively. Other properties were free fatty acid (1.55±0.89% oleic acid), peroxide value (3.23±0.55 meq O2/kg of oil), p-anisidine value (1.18±0.55) and refractive index (40 °C) (1.4687±0.00). As a result, M. alba seeds and oil along with its fatty acid, tocopherol, sterol and mineral composition can be used as nutritional supplements.
Journal of medical-clinical research & reviews, Aug 30, 2018
Dietary supplement market is growing in Turkey. Local and multinational companies develop and int... more Dietary supplement market is growing in Turkey. Local and multinational companies develop and introduce many new products for Turkish dietary supplements market. However, in marketing literature, a few academic researchers could be found regarding Turkish consumers' behavior about dietary supplements. Understanding the awareness and utilization rates of nutritional support products is important at the point of designing strategies for producers, the state and related organizations. This general exploratory research was carried out in 60 different pharmacies located in different regions
Journal of Medical - Clinical Research & Reviews, 2018
Dietary supplement market is growing in Turkey. Local and multinational companies develop and int... more Dietary supplement market is growing in Turkey. Local and multinational companies develop and introduce many new products for Turkish dietary supplements market. However, in marketing literature, a few academic researchers could be found regarding Turkish consumers' behavior about dietary supplements. Understanding the awareness and utilization rates of nutritional support products is important at the point of designing strategies for producers, the state and related organizations. This general exploratory research was carried out in 60 different pharmacies located in different regions
Herbal products have been in use for thousands of years. According to a notification issued by th... more Herbal products have been in use for thousands of years. According to a notification issued by the World Health Organization (WHO) [1], 70-80% of the world population uses herbal additives and supplements within the framework of basic healthcare services. It is stated that 60 billion USD are spent each year in the USA in this field while 5 billion USD were spent for “over-thecounter” products in Europe in 2003. This study is significant in terms of determining the strategy for healthcare requirements of people and the importance of visual and category design for food supplements in pharmacies in the field of sales and marketing in Turkey, the preferences of customers entering pharmacies, the contribution of campaigns to the sales, the ratios of product groups sold in pharmacies, the age range of customers entering pharmacies, the preferred price scale, the product variety within pharmacies as well as the importance of food supplements in our lives. This exploratory study is conducted with 219 pharmacists from various cities in the whole of Turkey. Data about the location of the pharmacy, the number of persons entering the pharmacy, the most preferred product categories, the age range, preferences and price scales, the contribution of campaigns to sales and the impact of in-pharmacy category management, product variety, visual quality on people and sales within the pharmacy are collected via a questionnaire. In this study, answers to the above-mentioned questions yielded positive results. Therefore, the importance of food supplements in pharmacies and the contribution to the sales of in-pharmacy categorization, visual quality and information were emphasized in this study
Journal of Pharmacy and Pharmacology 7 (2019) 564-577, 2019
Nigella sativa (NS) (Ranunculaceae family) is generally utilized as a therapeutic plant all over ... more Nigella sativa (NS) (Ranunculaceae family) is generally utilized as a therapeutic plant all over the world. The seeds of the plant have a long history of use in different frameworks of medicines and food. N. sativa seeds reveal a broad spectrum of pharmacological activities including immunopotentiation and antihistaminic, antiseptic, antiallergic, anti-hypertensive, anti-inflammatory, and antimicrobial activities. It is known as a source of thymoquinone (TQ), thymohydroquinone, dithymoquinone, p-cymene, carvacrol, 4-terpineol, t-anethol, sesquiterpene longifolene, nigellicimine and nigellicimine-N-oxide, α-pinene and thymol etc. Additionally, this is uncovered that the majority of therapeutic properties of this plant are due to the presence of thymoquinone which is a major bioactive component of the essential oil. The incalculable medicinal properties and therapeutic uses of N. sativa prove its importance as a valuable medicinal plant. The aim of this review is to summarize some imp...
Fig (Ficus carica Linn (Moraceae)) is a deciduous tree that grows in tropical and subtropical zon... more Fig (Ficus carica Linn (Moraceae)) is a deciduous tree that grows in tropical and subtropical zones [1]. Ficus carica has a broad spectrum of pharmacological activity and is widely used in traditional medicine. Research has found its use in more than 40 areas. Some of these are gastrointestinal, endocrine, respiratory, reproductive system disorders [2]. The fig seed oil contains alpha-linolenic acid (ALA), which is highly beta-sitosterol and herbal omega [3]. It can be used as a supplement in the treatment of diseases such as cardiovascular disorders, gastrointestinal disorders, and diabetes. Fig seed oil can be a good choice for skin hydration when used externally. In our study, the fig seed oil was analyzed by gas and liquid chromatography. In this study where linoleic acid (C18:2) and linolenic acid (C20:0) ratios found in fig seed oil composition were evaluated, the health benefits of two fatty acids were discussed based on the literature.
Nigella sativa (NS) (Ranunculaceae family) is generally utilized as a therapeutic plant all over ... more Nigella sativa (NS) (Ranunculaceae family) is generally utilized as a therapeutic plant all over the world. The seeds of the plant have a long history of use in different frameworks of medicines and food. N. sativa seeds reveal a broad spectrum of pharmacological activities including immunopotentiation and antihistaminic, antiseptic, antiallergic, anti-hypertensive, anti-inflammatory, and antimicrobial activities. It is known as a source of thymoquinone (TQ), thymohydroquinone, dithymoquinone, p-cymene, carvacrol, 4-terpineol, t-anethol, sesquiterpene longifolene, nigellicimine and nigellicimine-N-oxide, α-pinene and thymol etc. Additionally, this is uncovered that the majority of therapeutic properties of this plant are due to the presence of thymoquinone which is a major bioactive component of the essential oil. The incalculable medicinal properties and therapeutic uses of N. sativa prove its importance as a valuable medicinal plant. The aim of this review is to summarize some important pharmacological studies and phytochemical investigations on N. sativa and isolated principles which can be investigated further to get novel molecules in the search of novel herbal drugs.
Journal of the Turkish Chemical Society, Section A: Chemistry, May 15, 2019
This study has focused on Morus alba, which is grown in Turkey mostly for the production of fruit... more This study has focused on Morus alba, which is grown in Turkey mostly for the production of fruit. M. alba seeds' analysis results showed that oil, protein, ash, ash insoluble in hydrochloric acid, and total carbohydrate were, 21.33±0.58 g, 21.58±0.13 g, 3.99±0.13 g, 0.9±0.00 g, 54.76±2.42 g for 100 g of sample respectively; the main minerals were calcium, phosphorus, and potassium. Dominating fatty acids were linoleic acid (80.56±0.22%), palmitic acid (7.96±0.06%), oleic acid (7.11±0.05%). The primary volatiles were l-limonene, 2,2-dimethyldecane, and hexanal. Sterol components were found as beta-sitosterol>delta-5-avenasterol>campesterol>cholestenol and the total sterols' amount was 5501.49±44.26 mg/kg. δ-tocopherol, γ-tocopherol, β-tocopherol, α-tocopherol, total phenolic content, the radical scavenging activity were 257.67±4.51 mg/kg, 18.23±0.11 mg/kg, 6.71±0.13 mg/kg, 3.23±0.06 mg/kg, 137.1±0.36 mgGAE/100 g oil, 19.9±0.46% respectively. Other properties were free fatty acid (1.55±0.89% oleic acid), peroxide value (3.23±0.55 meq O2/kg of oil), p-anisidine value (1.18±0.55) and refractive index (40 °C) (1.4687±0.00). As a result, M. alba seeds and oil along with its fatty acid, tocopherol, sterol and mineral composition can be used as nutritional supplements.
Journal of medical-clinical research & reviews, Aug 30, 2018
Dietary supplement market is growing in Turkey. Local and multinational companies develop and int... more Dietary supplement market is growing in Turkey. Local and multinational companies develop and introduce many new products for Turkish dietary supplements market. However, in marketing literature, a few academic researchers could be found regarding Turkish consumers' behavior about dietary supplements. Understanding the awareness and utilization rates of nutritional support products is important at the point of designing strategies for producers, the state and related organizations. This general exploratory research was carried out in 60 different pharmacies located in different regions
Journal of Medical - Clinical Research & Reviews, 2018
Dietary supplement market is growing in Turkey. Local and multinational companies develop and int... more Dietary supplement market is growing in Turkey. Local and multinational companies develop and introduce many new products for Turkish dietary supplements market. However, in marketing literature, a few academic researchers could be found regarding Turkish consumers' behavior about dietary supplements. Understanding the awareness and utilization rates of nutritional support products is important at the point of designing strategies for producers, the state and related organizations. This general exploratory research was carried out in 60 different pharmacies located in different regions
Herbal products have been in use for thousands of years. According to a notification issued by th... more Herbal products have been in use for thousands of years. According to a notification issued by the World Health Organization (WHO) [1], 70-80% of the world population uses herbal additives and supplements within the framework of basic healthcare services. It is stated that 60 billion USD are spent each year in the USA in this field while 5 billion USD were spent for “over-thecounter” products in Europe in 2003. This study is significant in terms of determining the strategy for healthcare requirements of people and the importance of visual and category design for food supplements in pharmacies in the field of sales and marketing in Turkey, the preferences of customers entering pharmacies, the contribution of campaigns to the sales, the ratios of product groups sold in pharmacies, the age range of customers entering pharmacies, the preferred price scale, the product variety within pharmacies as well as the importance of food supplements in our lives. This exploratory study is conducted with 219 pharmacists from various cities in the whole of Turkey. Data about the location of the pharmacy, the number of persons entering the pharmacy, the most preferred product categories, the age range, preferences and price scales, the contribution of campaigns to sales and the impact of in-pharmacy category management, product variety, visual quality on people and sales within the pharmacy are collected via a questionnaire. In this study, answers to the above-mentioned questions yielded positive results. Therefore, the importance of food supplements in pharmacies and the contribution to the sales of in-pharmacy categorization, visual quality and information were emphasized in this study
Journal of Pharmacy and Pharmacology 7 (2019) 564-577, 2019
Nigella sativa (NS) (Ranunculaceae family) is generally utilized as a therapeutic plant all over ... more Nigella sativa (NS) (Ranunculaceae family) is generally utilized as a therapeutic plant all over the world. The seeds of the plant have a long history of use in different frameworks of medicines and food. N. sativa seeds reveal a broad spectrum of pharmacological activities including immunopotentiation and antihistaminic, antiseptic, antiallergic, anti-hypertensive, anti-inflammatory, and antimicrobial activities. It is known as a source of thymoquinone (TQ), thymohydroquinone, dithymoquinone, p-cymene, carvacrol, 4-terpineol, t-anethol, sesquiterpene longifolene, nigellicimine and nigellicimine-N-oxide, α-pinene and thymol etc. Additionally, this is uncovered that the majority of therapeutic properties of this plant are due to the presence of thymoquinone which is a major bioactive component of the essential oil. The incalculable medicinal properties and therapeutic uses of N. sativa prove its importance as a valuable medicinal plant. The aim of this review is to summarize some imp...
Fig (Ficus carica Linn (Moraceae)) is a deciduous tree that grows in tropical and subtropical zon... more Fig (Ficus carica Linn (Moraceae)) is a deciduous tree that grows in tropical and subtropical zones [1]. Ficus carica has a broad spectrum of pharmacological activity and is widely used in traditional medicine. Research has found its use in more than 40 areas. Some of these are gastrointestinal, endocrine, respiratory, reproductive system disorders [2]. The fig seed oil contains alpha-linolenic acid (ALA), which is highly beta-sitosterol and herbal omega [3]. It can be used as a supplement in the treatment of diseases such as cardiovascular disorders, gastrointestinal disorders, and diabetes. Fig seed oil can be a good choice for skin hydration when used externally. In our study, the fig seed oil was analyzed by gas and liquid chromatography. In this study where linoleic acid (C18:2) and linolenic acid (C20:0) ratios found in fig seed oil composition were evaluated, the health benefits of two fatty acids were discussed based on the literature.
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