Papers by Antonio Carrassi
International journal of computerized dentistry, 2021
AIM The aim of the present study was to verify the possibility of obtaining an optimized prosthet... more AIM The aim of the present study was to verify the possibility of obtaining an optimized prosthetic substructure using generic software, respecting the distribution loads and forces involved. What is considered to be original and innovative in this study is the possibility of designing the prosthetic substructure on the basis of the individual patient's chewing biomechanics, with the purpose of obtaining an even greater efficiency than a prosthesis designed according to a traditional method. MATERIALS AND METHODS The starting standard triangulation language (STL) file was processed with Rhinoceros software and the tOpos plugin. It was decided to submit the entire prosthetic solution, intended as total volume, to structural analysis and topological optimization because the entire prosthesis is subjected to load during the chewing act. The software program was provided with information on the material, modulus, and direction of the applied forces. The objective was to optimize sti...
Cochrane Database of Systematic Reviews, Jul 19, 2004
Analysis 1.1. Comparison 1 Topical or systemic treatment versus placebo, Outcome 1 Malignant tran... more Analysis 1.1. Comparison 1 Topical or systemic treatment versus placebo, Outcome 1 Malignant transformation.. . Analysis 1.2. Comparison 1 Topical or systemic treatment versus placebo, Outcome 2 Oral lesion not completely resolved. Analysis 1.3. Comparison 1 Topical or systemic treatment versus placebo, Outcome 3 Histological features not improved.
Journal of Osseointegration, Oct 30, 2010
Aim Bisphosponates are the most important class of antiresorptive agents commonly used in the man... more Aim Bisphosponates are the most important class of antiresorptive agents commonly used in the management of osteoporosis, Paget' s disease, and tumor-associated osteolysis. Oral bisphosphonateinduced osteonecrosis is a rare but real entity caused by the antiosteoclastic effects of bisphosphonates which inhibit bone turnover. The aim of this work is to determine the extent to which bisphosphonate-associated osteonecrosis occurs after dental implant surgery. We also wanted to determine whether there was any indication that bisphosphonates affected the overall success of the implants. Materials and methods We described 21 patients undergoing dental implants surgery who were taking or had taken oral bisphosphonates. All patients were informed about the risk of osteonecrosis and a written informed consent was obtained from each individual. Results A total of 38 implants were placed in 21 patients who reported having received oral bisphosphonates. None had received intravenous bisphosphonates. There is no evidence of osteonecrosis in any of the patients evaluated. Of the 38 implants, all but 2 fully integrated and met implant success criteria. Conclusion Implant surgery on patients receiving oral bisphosphonates did not result in osteonecrosis. Moreover, oral bisphosphonates did not appear to significantly affect implant success. Nevertheless, sufficient evidence exists to suggest that all patients undergoing implant placement should be questioned about bisphosphonate therapy including the drug taken, the dosage, and length of treatment prior to surgery.
PubMed, Jun 1, 1996
In 1988 the RNA virus responsible for the majority of cases of parenteral non A, non B hepatitis ... more In 1988 the RNA virus responsible for the majority of cases of parenteral non A, non B hepatitis (NANBH) was isolated and designated Hepatitis C Virus (HCV). Since then, the sequence of the genome of the virus has been defined and at least 10 different types identified. Clinical studies indicate that the majority of patients who acquire HCV develop chronic hepatic disease, in particular chronic active hepatitis or cirrhosis and some of them will develop hepatocellular carcinoma. Currently, there is no effective anti-HCV therapy and no passive or active immunization protocol for HCV. Epidemiological studies indicate that HCV infection is relatively well confined to specific patient populations, in particular injecting drug users and recipients of blood and blood products. Nevertheless as HCV infection is transmitted mainly parenterally it must be regarded as a potential hazard for dental health care staff. This article reviews current knowledge concerning HCV infection with particular attention to those issues relevant to the dentists in Italy including the dental management of the HCV infected patient and the risk of HCV cross-infection in the dental environment.
Journal of Dental Research, 1998
The Cochrane library, Nov 14, 2012
Background The most frequent indications for tooth extractions are dental caries and periodontal ... more Background The most frequent indications for tooth extractions are dental caries and periodontal infections, and these extractions are generally done by general dental practitioners. Antibiotics may be prescribed to patients undergoing extractions to prevent complications due to infection. Objectives To determine the effect of antibiotic prophylaxis on the development of infectious complications following tooth extractions.
Journal of Orthopaedics and Traumatology
This joint report from the Italian Society of Orthopaedics and Traumatology (SIOT) and the Italia... more This joint report from the Italian Society of Orthopaedics and Traumatology (SIOT) and the Italian Society of Periodontology and Implantology (SIdP) aims for a consensus around the scientific rationale and clinical strategy for the management of osteoporotic patients affected by periodontitis who are undergoing anti-resorptive (AR) therapy to manage the risk of the occurrence of a medication-related osteonecrosis of the jaws (MRONJ). Osteoporosis and periodontitis are chronic diseases with a high prevalence in aging patients, and they share some of the same pathogenetic mechanisms based upon inflammation. Available evidence shows the relationship among osteoporosis, AR agents, periodontitis and implant therapy in relation to the incidence of MRONJ. Uncontrolled periodontitis may lead to tooth loss and to the need to replace teeth with dental implants. Tooth extraction and surgical dental procedures are recognized as the main risk factors for developing MRONJ in individuals taking AR...
Congresso Nazionale S.I.O.C.M.F., 1987
The administration of many chemo-radiotherapy regimens in patients with cancer may be complicated... more The administration of many chemo-radiotherapy regimens in patients with cancer may be complicated by toxicities that limit the clinicians' abilities to deliver the most effective doses of active agents. Oral mucositis is a major dose-limiting toxic effect and the most important cause of morbidity in patients undergoing chemo-radiotherapy for head and neck cancers, in patients undergoing bone marrow transplantation and those receiving certain chemotherapeutic agents for a variety of human malignancies. The intent of this paper is to review preventive strategies and treatment approaches for patients with established oral mucositis. Many agents of differing mechanisms of action have been used in the prevention and treatment of oral mucositis induced by anticancer therapies. Currently, no intervention is completely successful at preventing or treating oral mucositis. The several solutions, drugs and methods used and studied in the prophylaxis and therapy of chemotherapy or radiotherapy-induced oral mucositis reflects the need of new, more efficient tools in the management of this complication. Current studies and our increasing understanding of the etiology and pathogenesis of oral mucositis will lead to new approaches to the management and improved quality of life for these patients
Journal of Applied Biomaterials & Functional Materials, 2003
This study aimed to assess the effect of chemical composition, wettability and roughness on the c... more This study aimed to assess the effect of chemical composition, wettability and roughness on the clinical reduction of plaque colonization after 24 hr. Grade 1 commercially pure titanium (c. p. Ti) was oxygen ion-implanted and anodized. The specimens were measured for surface roughness and wettability. Chemical composition was investigated by electron spectroscopy chemical analysis (ESCA). Volunteers had the specimens implanted into their mouths. After 24 hr, they were removed and observed by scanning electron microscopy (SEM). A global area of 100 x 125 mm consisting of randomly selected fields was examined for each specimen. The density of bacteria and morphotypes were recorded for each field. The data reported for the global area are the sum of those observed in the selected fields. The number of bacteria adhering to the treated surfaces significantly differed between specimens and related directly to wettability and roughness. The type of bacteria adhering to the surfaces ranged ...
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Papers by Antonio Carrassi