Angel Nava

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Anil Sukumaran

Hamad Medical Corporation

Eloi Dezan

Universidade Estadual Paulista "Júlio de Mesquita Filho"

Dr. Carlos San Martin D.

San Martin de Porres University

Maria Georgopoulou

National & Kapodistrian University of Athens

Liviu Steier

University of Pennsylvania

Manoel Damiao Sousa Neto

Universidade de São Paulo

Paul Abbott

The University of Western Australia

Claudia Carmina Garcia Guerrero

Universidad Nacional de Colombia (National University of Colombia)

JOSE LUIS ALVAREZ VASQUEZ

Universidad de Cuenca, Ecuador

Valentina Fajreldin Chuaqui

Universidad de Chile

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Papers by Angel Nava

Study of the expression of CD30 in pterygia compared to healthy conjunctivas

Molecular vision, Jan 17, 2009

The pterygium is characterized by a fibrovascular neoformation from the bulbar conjunctiva into t... more The pterygium is characterized by a fibrovascular neoformation from the bulbar conjunctiva into the cornea. The recent discovery that abnormal markers associated with tumor diseases are identified in the pterygium strengthens the theory that the pterygium is a tumor-like disease rather than a degenerative disease. The CD30 molecule has been identified in neoplastic and normal epithelial proliferating cells. The aim of this study was to determine the expression of the CD30 molecule in the pterygium. Immunohistochemical staining using an antibody to CD30 and to the Ki-67 nuclear antigen was performed on 25 pterygial specimens and 10 healthy conjunctivas. Strong immunostaining against CD30 was observed in all pterygium specimens, in contrast to the healthy conjunctivas that showed weak immono-positivity in only three cases. The staining was diffused, predominantly to the basal epithelium. The Ki-67 antigen was observed in the nucleus of the basal epithelium of the pterygial specimens, ...

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