Papers by AUGUSTO CUBAS CAMPOS
Poster Presentations, 2021
Ideas Y Valores, Aug 1, 2005
El reconocimiento y el olvido imposible.
Docentia Et Investigatio, 2011
European Journal of Pharmacology, 1977
Foot shocks applied to the rat on a grid floor caused brain noradrenaline depletion. Hemicholiniu... more Foot shocks applied to the rat on a grid floor caused brain noradrenaline depletion. Hemicholinium-3 injected intracerebroventricularly (i.c.v.) blocked the noradrenaline depletion and this blockade was reversed by choline (i.c.v.). Physostigmine (i.c.v.) had different effects according to the age of the rats: "young" and "intermediate" groups were depleted but not "adult" groups. Physostigmine plus shocks caused depletion only in "young" groups; the depletion not shown in "intermediat" groups, reappeared after pretreatment with alpha-methyl-p-tyrosine. It is concluded that there probably is a relationship between cholinergic and adrenergic neural systems when brain noradrenaline id depleted by shocks.
European Journal of Pharmacology, 1998
We have previously shown the existence of a novel peripheral reflex inhibitorily modulating the v... more We have previously shown the existence of a novel peripheral reflex inhibitorily modulating the vas deferens sympathetic activity. An interaction between noradrenergic and histamine-containing neurons is involved in this reflex. As an overall mechanism of sympathetic autoregulation, we found that enhanced sympathetic activity in the rat during the stress induced by brief inescapable footshocks caused a marked rise of blood histamine that was seemingly dependent upon sympathetic activity. This rise was prevented by either previous ganglionic blockade with hexamethonium or chronic guanethidine-induced sympathectomy. Previous adrenal demedullation did not impair this rise. Thus, it appears that only the sympathetic postganglionic neuron, interacting with a histamine-containing neuron, is involved in the rise of blood histamine induced by footshocks. q 1998 Elsevier Science B.V.
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Papers by AUGUSTO CUBAS CAMPOS