Papers by 14- Phạm Nguyễn Khánh Hưng-c10
Chemistry & Biodiversity
The stilbene‐rich acetone fraction in high yield (6.6 %, PEAS) of Passiflora edulis Sims was prep... more The stilbene‐rich acetone fraction in high yield (6.6 %, PEAS) of Passiflora edulis Sims was prepared and evaluated for neuroprotective activity in murine Alzheimer's disease model induced by aluminum chloride and D‐galactose. The phytochemical and HPLC‐DAD‐MS analysis of the polyphenolic stilbene‐rich acetone fraction showed that it contained different stilbenes including trans‐piceatannol, scirpusins A−B and cassigarol E. The total phenolic content (TPC) of PEAS was 413.87±1.71 mg GAE eqv/g. The neuroprotective activity of PEAS is typically presented in the Morris water maze‐reference Spatial Memory test, where the Alzheimer's mice treated at 100 mg/kg (Alz‐ED1) and 200 mg/kg (Alz‐ED2) spent less than 47 % and 66 % of the time, respectively, than the Alzheimer's model mice (Alz). Two simple stilbenes, trans‐piceatannol and trans‐resveratrol, showed selectively inhibitory activity in silico against acetylcholinesterase (AChE). Two stilbene dimers, cassigarol E and scirp...
Carbon Dioxide Chemistry, Capture and Oil Recovery
In this chapter, interactions of CO 2 with a number of organic compounds at molecular level are d... more In this chapter, interactions of CO 2 with a number of organic compounds at molecular level are discussed in detail. The naked and substituted hydrocarbons along with compounds functionalized by hydroxyl, carbonyl, thiocarbonyl, carboxyl, sulfonyl, and amide groups have attracted much attention as CO 2-philic agents. In general, interaction capacity between the functionalized organic compounds with CO 2 is stronger than the hydrocarbon and its derivatives. An addition of more CO 2 molecules into the interaction system formed by the functionalized organic compounds and CO 2 leads to an increase in the stability of the complexes. The obtained results indicate that π…π linkages between CO 2 and aromatic rings can significantly contribute to the interactions between CO 2 and MOF/ZIF materials. Formic acid (HCOOH) is likely to be the most soluble compound as compared to the remaining host molecules (CH 3 OH, CH 3 NH 2 , HCHO, HCOOCH 3 , and CH 3 COCH 3) when dissolved in CO 2. The carbonyl (>C═O, >C═S) and sulfonyl (>S═O, >S═S) compounds have presented a higher stability, as compared to other functionalized groups, when they interact with CO 2. Therefore, they can be valuable candidates in the design of CO 2-philic materials and in the search of materials to adsorb CO 2 .
2016 International Conference on ReConFigurable Computing and FPGAs (ReConFig)
Option Pricing is a fundamental application in most financial institutions dealing with derivativ... more Option Pricing is a fundamental application in most financial institutions dealing with derivative market. It frequently requires huge computational effort and low latency demand. Therefore, a number of different Option Pricing implementations have been developed on FPGA-based platform. However, none of the existing works cover more than one models or different types of options, which yields problem of productively implementing several hardware accelerators for different models. To fill in the gap, we propose a design flow for generating efficient hardware accelerators for option pricing applications with different models and option types. The framework boosts the designers productivity and enables quick prototyping on FPGA platform by providing general template architecture for option pricing applications. The architecture comes along with a prebuilt design library, which covers a wide range of popular financial models. Experimental results for four models show that the accelerators generated from our design flow outperform their counterpart software implementation with two order of magnitude speedup. While comparing with existing hardware designs for the same models, our framework can produce the accelerators that overcome most of manual designed engines.
KINH TẾ VÀ QUẢN TRỊ KINH DOANH, 2020
Mục tiêu của bài viết là phân tích, đánh giá chất lượng tăng trưởng kinh tế của vùng kinh tế trọn... more Mục tiêu của bài viết là phân tích, đánh giá chất lượng tăng trưởng kinh tế của vùng kinh tế trọng điểm (KTTĐ) phía Nam nhìn từ góc độ kinh tế. Bài viết sử dụng các chỉ tiêu kinh tế để phân tích như: tốc độ tăng trưởng kinh tế, GDP bình quân đầu người, cơ cấu GDP và tốc độ tăng trưởng GDP phân theo khu vực kinh tế, giá trị xuất nhập khẩu, tốc độ tăng trưởng và tỷ trọng xuất nhập khẩu của vùng; bằng cách sử dụng các chỉ tiêu kinh tế như phương pháp hạch toán để xác định tỷ phần đóng góp của các nhân tố vốn, lao động và TFP; phân tích hiệu quả vốn đầu tư (ICOR), năng suất lao động và tiến bộ khoa học công nghệ; phân tích năng lực cạnh tranh của các tỉnh, thành phố của vùng. Kết quả cho thấy, tăng trưởng của vùng có xu hướng chậm lại và thiếu bền vững; tỷ trọng đóng góp của nhân tố TFP trong GDP có xu hướng giảm, chất lượng tăng trưởng và năng lực cạnh tranh trong điều kiện hội nhập chưa cao; chuyển dịch cơ cấu nội bộ các ngành kinh tế còn chậm, từ đó bài viết đề xuất một số giải pháp ...
Proceedings of SPIE, 2019
Microprocessors and Microsystems, 2016
Natural Product Sciences, 2019
Planta Medica, 2020
Dalbergia species heartwood, widely used in traditional medicine to treat various cardiovascular ... more Dalbergia species heartwood, widely used in traditional medicine to treat various cardiovascular diseases, might represent a rich source of vasoactive agents. In Vietnam, Dalbergia tonkinensis is an endemic tree. Therefore, the aim of the present work was to investigate the vascular activity of R-(−)-3′-hydroxy-2,4,5-trimethoxydalbergiquinol isolated from the heartwood of D. tonkinensis and to provide circular dichroism features of its R absolute configuration. The vascular effects of R-(−)-3′-hydroxy-2,4,5-trimethoxydalbergiquinol were assessed on the in vitro mechanical activity of rat aorta rings, under isometric conditions, and on whole-cell Ba2+ currents through CaV1.2 channels (IBa1.2) recorded in single, rat tail main artery myocytes by means of the patch-clamp technique. R-(−)-3′-Hydroxy-2,4,5-trimethoxydalbergiquinol showed concentration-dependent, vasorelaxant activity on both endothelium-deprived and endothelium intact rings precontracted with the α 1 receptor agonist phe...
In opdracht van het ministerie van economische zaken onderzoekt ECN (Energie Centrum Nederland, e... more In opdracht van het ministerie van economische zaken onderzoekt ECN (Energie Centrum Nederland, een onderdeel van TNO) de energieproductie uit hernieuwbare organische bronnen. Pyrolyse en gassificatie zijn technieken waarmee groen aardgas en platform chemicaliën gemaakt kunnen worden. Een ander optie is dat in co-productie bio-energie en biochar worden gemaakt. De economische haalbaarheid wordt sterk verbeterd als biochar als co-product een significante positieve waarde krijgt als onderdeel van potgronden in de glastuinbouw. Wageningen University & Research Glastuinbouw onderzoekt in dat kader of biochar gebruikt kan worden voor twee doeleinden. Het eerste doel is biochar als duurzamer veenalternatief in een potgrondmengsel voor de teelt van aardbeien. Het tweede doel is het gebruik van biochar als drager voor nuttige micro-organismen voor de teelt van aardbeien. In een teeltexperiment is gekeken naar groei-effecten bij het gebruik van een reeks verschillende biochar-veen mengsels. Daarbij is Trichoderma toegevoegd om de plant tegen een toediening van de ziekteverwekker Phytophthora te beschermen. De resultaten tonen dat 10, 20 of 30% v/v biochar in een veengrond geen effect heeft op vers en drooggewicht van de blad en stengel massa maar wel leidt tot een 5-10% hogere productie van vruchten. Het toedienen van Trichoderma met biochar leidde niet tot een betere overleving van Trichoderma. De toegediende Phytophthora leidde niet tot een verhoogde kans op ziekte in de aardbeiplanten maar de Phytophthora druk is lager als het percentage biochar toeneemt.
Vietnam Journal of Science and Technology, 2019
The present research was aimed to study the chemical compositions of Passiflora edulis Sims seeds... more The present research was aimed to study the chemical compositions of Passiflora edulis Sims seeds oil, including the fatty acid profiles, contents of tocopherols, sterols, and triglycerides. The seeds oil yield is 24.88% by using Soxhlet method. Passiflora edulis seeds oil showed high levels of unsaturated fatty acids (89.25%) with main ingredient linoleic acid (w-6, 66.94%) and oleic acid (w-6, 18.86%). Tocopherols (18.04 mg/kg), sterols (2935.35 mg/kg) and triglycerides (monomere TAG, 74.11%) are also determined by using IOC and ISO methods, respectively. The findings demonstrate that P. edulis seeds oil could be used beneficially in the food and cosmetic industries.
Vietnam Journal of Science and Technology, 2019
Study on chemical constituents from the leaves and stems of Dysoxylum tpongense Pierre resulted i... more Study on chemical constituents from the leaves and stems of Dysoxylum tpongense Pierre resulted in the isolation of six known compounds (1–6). The chemical structures of isolated compounds were identified as cabraleahydroxylactone (1), cabraleahydroxylactone-3-acetate (2), (+) spathulenol (3), b-sitosterol (4), stigmasterol (5), and stigmast-4-en-3-one (6) by comparison of the physicochemical, interpretation of NMR and mass spectral data with that reported in the literature.
Journal of computational chemistry, Jan 3, 2018
Interactions of dimethyl sulfoxide with carbon dioxide and water molecules which induce 18 signif... more Interactions of dimethyl sulfoxide with carbon dioxide and water molecules which induce 18 significantly stable complexes are thoroughly investigated. An addition of CO or H O molecules into the DMSO⋯1CO and DMSO⋯1H O systems leads to an increase in the stability of the resulting complexes, in which it is larger for a H O addition than a CO . The overall stabilization energy of the DMSO⋯1,2CO is mainly contributed by the S=O⋯C Lewis acid-base interaction, whereas the O - H⋯O hydrogen bond plays a significant role in stabilizing complexes of DMSO⋯1,2H O and DMSO⋯1CO ⋯1H O. Remarkably, the complexes of DMSO⋯2H O are found to be more stable than DMSO⋯1CO ⋯1H O and DMSO⋯2CO . The level of the cooperativity of multiple interactions in ternary complexes tends to decrease in going from DMSO⋯2H O to DMSO⋯1CO ⋯1H O and finally to DMSO⋯2CO . It is generally found that the red shift of the O - H bond involved in an O - H⋯O hydrogen bond increases while the blue shift of a C - H bond in a C - H...
Bulletin of the Korean Chemical Society, 2017
Planta Medica International Open, 2017
Microprocessors and Microsystems, 2016
RSC Advances, 2016
Theoretical calculations at the MP2/aug-cc-pVDZ level are used to investigate the Csp–H⋯π interac... more Theoretical calculations at the MP2/aug-cc-pVDZ level are used to investigate the Csp–H⋯π interactions of C2HX (X = H, F, Cl, Br, CH3, NH2) with C6H6 and B3N3H6 molecules.
Vietnam Journal of Science and Technology, 2016
Phytochemical investigation of the leaves and stems of Callistemon citrinus (Curtis) Skeels led t... more Phytochemical investigation of the leaves and stems of Callistemon citrinus (Curtis) Skeels led to the isolation of 12 flavonoid and triterpenoid compounds, including one new flavonoid, callistine A (1) and six known flavonoids 6,7- dimethyl-5,7-dihydroxy-4’-methoxy flavone (2), astragalin (3), quercetin (4), catechin (5), eucalyptin (6), and 8-demethyleucalyptin (7), along with 5 triterpenoids, 3-β-acetylmorolic acid (8), 3β-hydroxy-urs-11-en-13(28)-olide (9), betulinic acid (10), diospyrolide (11) and ursolic acid (12). Their chemical structures were determined from the spectroscopic evidences counting 1D- and 2D-NMR and HR-MS data. All the isolated compounds were examined for their anti-inflammatory activity against LPS-activated NO production in macrophage RAW264.7 cells. Among them, quercetin (4) and 3β-hydroxy-urs-11-en-13(28)-olide (9) showed potential inhibition activity in nitric oxide (NO) production in RAW264.7 cells exposed to LPS.
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Papers by 14- Phạm Nguyễn Khánh Hưng-c10