Indian Journal of Obstetrics and Gynecology Research, Aug 15, 2022
First trimester in pregnancy is majorly about "Organogenesis", formation and development of embry... more First trimester in pregnancy is majorly about "Organogenesis", formation and development of embryo, and then progression to fetus. Insult to the stages of this organogenesis leads to various anomalies; including malformations. Lack of nutrition, folate deficiency, genetic factors, teratogenic drugs or environmental exposure can lead to such malformed embryo/fetus. Viability of such fetus depends on the system affected, and the severity. Many fetus do not survive major defects, but some may reach to the stage of live births, causing major problems for survival, growth and development. The psychological impact on the couple, along with future financial strain on possible treatments are additional burdens. There have been few investigations, now made available for diagnosing many of such malformations in earlier stages of pregnancy; making us able to detect them, so that with proper counselling of the couple and possible outcome, we can take decisions on continuation or termination of pregnancy. This was a prospective study, where we studied 200 newborns who were born with congenital malformations, during time period of January 2017 to December 2019. There were total 15687 deliveries in the said time period, making the incidence of congenital malformations to be 1.27%. Most commonly involved system was central nervous system (39%), followed by musculoskeletal system (25%), followed by gastrointestinal system (11%). This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
Indian Journal of Obstetrics and Gynecology Research, May 15, 2023
Background: Anaemia during pregnancy is allied with maternal and foetal complications like increa... more Background: Anaemia during pregnancy is allied with maternal and foetal complications like increased risk of intrauterine growth retardation, prematurity, low birth weight, and maternal and infant mortality. The agent iron isomaltose 1000 (Fur-IV) combines iron and isomaltose 1000 for slow, controlled release to reduce the risk of free iron toxicity and provide flexibility and convenience for high dose administration. Iron isomaltoside has been shown to be effective in the treatment of IDA in many treatment groups compared to intravenous iron sucrose and FCM. Materials and Methods: It is a prospective interventional study which is conducted to observe an increase in hemoglobin levels in obstetric and gynecological department patients suffering from IDA in whom oral iron preparation was ineffective or in case of clinical need to supply iron rapidly via single infusion of iron isomaltoside 1000. Each patient in the study received 500 mg single intravenous infusion. After this, patient was followed up and haemogram was repeated after 15 and 30 days of infusion while investigation for serum ferritin and serum iron was repeated after 30 days. Results: Average Hb concentration in increased by 30.86% to 9.88 g/dL after 30 days of infusion. There is statistically significant difference between baseline values and post infusion 30 days values for serum ferritin and serum iron (p-value <0.0001 for both). Conclusion: IV iron isomaltoside administration was well tolerated in patients with gynecological IDA who were intolerant or unresponsive to oral iron therapy or who required rapid iron administration. This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
Indian Journal of Obstetrics and Gynecology Research, Dec 15, 2020
Craniosynostosis is a condition of one or more of the fibrous sutures in an infant skull prematur... more Craniosynostosis is a condition of one or more of the fibrous sutures in an infant skull prematurely fuses by turning into bone (ossification). 1 Premature fusion of cranial sutures may have an effect on cranial shape an less frequently on brain growth. 2 There is a changing in the growth pattern of the skull and the skull can't expand perpendicular to the fused suture, craniosynostosis can lead to abnormal head shape and abnormal facial features and results in increased intracranial pressure leading possibly to visual difficulty, sleeping impairment, eating problem, or impaired mental status with a significant reduction in IQ.
Indian Journal of Obstetrics and Gynecology Research, Jun 15, 2021
Background: One of the most frequent causes of neonatal mortality or NICU admission of neonates e... more Background: One of the most frequent causes of neonatal mortality or NICU admission of neonates especially in premature infants is Neonatal Respiratory Distress Syndrome (NRDS). Antenatal steroids are the most important and widely utilized interventions for improvement of neonatal outcomes like reducing incidence of respiratory distress syndrome (RDS), reducing neonatal NICU (neonatal intensive care unit) admission rates and also improve outcomes of pre-term infants. Antenatal steroids (ANS) like betamethasone 12 mg are given at 24 hourly IM at 28-34 weeks of gestation to mother. For administration of corticosteroids at less than 24 weeks of gestational age decision should be made at a senior level by taking all clinical aspects into consideration. Objective: To observe the effect of Betamethasone administration IM in pregnant women at risk of preterm delivery and fetal outcomes in terms of development of Respiratory Distress Syndrome (RDS) and Neonatal Intensive Care Unit (NICU) admission rate by giving it between 28 to 34 weeks of gestation. Introduction: Antenatal corticosteroids (betamethasone) play an important role for prevention of respiratory distress syndrome and reducing NICU admission rate of new borns and also reduce neonatal mortality and morbidity but benefits related to the time between administration of corticosteroid and delivery needed to be explored. Benefits of the injection betamethasone administration IM 12 mg between 24 hours and seven days on pre-term delivery has been established. 1,2 Methods: This was prospective study conducted in private setup from November 2020 to March 2021 in Scientific Research Institute, Surendranagar, Gujarat, India. Study comprised of 100 women with single tone pregnancies (28-36 weeks gestational age) in age group of 19-33 years not in labour, but at risk for pre-term delivery based on fetal or maternal indications. These pregnant women were treated with two doses of 12 mg Betamethasone Intramuscularly apart of 24 hourly for maturation of fetal lungs. Conclusion: Antenatal corticosteroids like betamethasone have a significant benefit on neonatal outcome even if used after 34 weeks of pregnancy. This was given prophylactically to those who are known to have increased risk of pre-term labour. Antenatal steroid like betamethasone 12 mg IM is also of benefit to reduce neonatal respiratory distress syndrome (NRDS) and NICU admission rates by giving it at 28-34 weeks of gestational age.
Indian Journal of Obstetrics and Gynecology Research, Feb 15, 2022
Dextrocardia is a clinical condition in which heart is located on the right side of the chest cav... more Dextrocardia is a clinical condition in which heart is located on the right side of the chest cavity. Dextroversion is a result of early interruption of normal embryological development and therefore, rarely occurs without other cardiac and noncardiac anomalies. Isolated dextrocardia is a benign condition. It can often be associated with other congenital anomalies which can lead to failure to thrive, breathing difficulties, recurrent infections in new borns and neonates. It presents in situs solitus and situs inversus. Among them Dextrocardia with situs solitus is very rare. We are here presenting a case of dextrocardia with situs solitus. This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
Indian Journal of Obstetrics and Gynecology Research
To evaluate efficacy and safety of the FotonaSmooth device in treatment of SUI (stress urinary in... more To evaluate efficacy and safety of the FotonaSmooth device in treatment of SUI (stress urinary incontinence) patients after treating them with Er: YAG laser using both objective and patient-reported outcomes. Stress urinary incontinence (SUI) is a leakage of urine during moments of physical activity that increases abdominal pressure, such as coughing, sneezing, laughing, or exercise. It is most common seen health problem among women of certain age and it is most common type of urinary incontinence in women. Here, SUI is treated using intravaginal laser therapy by using non ablative Er: YAG (erbium-doped yttrium aluminium garnet) laser with SMOOTH mode technology.: The 96 parous women with SUI were treated according to IncontiLaseclinical treatmentprotocol by using non-ablative Er: YAG (erbium-doped yttrium aluminium garnet) laser with SMOOTH mode technology at Vcare laser centre state of art centre for cosmetic gynaecology, Indore, Madhya Pradesh. At baseline, at 2 months and at 9 m...
Indian Journal of Obstetrics and Gynecology Research, 2017
A 55 year old postmenopausal woman was brought to casualty department of C. U. Shah Medical Colle... more A 55 year old postmenopausal woman was brought to casualty department of C. U. Shah Medical College and Hospital with history of fall down with lower abdominal pain and vomiting. Patient having history of lower abdominal pain, non foul smelling whitish discharge, low grade on and off fever since 1 year associated with gradual weight loss since 2 years. Per abdominal examination reveals tender, distended with muscle rigidity. Exploratory laparotomy was performed under the diagnosis of perforation of GI tract with x-ray showing free gas under diaphragm. On exploration, the uterus was found to have fundal perforation of size 2x2 cm in dimension. With purulent material extruding from uterine cavity and abdominal cavity filled with purulrnt discharge around 1.5 litre. A Total abdominal hysterectomy with bilateral Salpingoophrectomy was performed uneventful and peritoneal cavity wash given with normal saline multiple times. Patient recovered completely without any complications and was di...
The Posterior Reversible Encephalopathy Syndrome is a neurological condition described on 1996, d... more The Posterior Reversible Encephalopathy Syndrome is a neurological condition described on 1996, developed in patients with complex systemic conditions, especially pregnant women with preeclampsia that at the same time presented neurological signs as seizures, headache, visual loss, and vomiting in addition to posterior brain edema, visible on neuroimaging and located in parietal and occipital lobes, that usually reverses completely. We present two clinical cases with PRES and eclampsia, antenatal and post-partum, both with seizure and confi rmed brain edema with Nuclear Magnetic Resonance. Both had a favorable evolution after the anticonvulsivant and anti-hypertensive therapy were done. We discuss the controversy over pathophysiolgical mechanisms, the new methods for diagnosis and management and the importance of multidisciplinary approach.
Indian Journal of Obstetrics and Gynecology Research, 2017
A 30 year old female, gravida 3, para 2 with two previous full term normal vaginal deliveries and... more A 30 year old female, gravida 3, para 2 with two previous full term normal vaginal deliveries and a history of 9 months of amenorrhea was referred to C. U. Shah Medical college and Hospital for severe anemia with complaints of lower abdominal pain and breathlessness. Abdomen was soft, non-tender and unduly enlarged. Fetal heard sounds were absent. Laparotomy was performed under diagnosis of uterine rupture. Uterus was found to have ruptured from the posterior wall and was beyond repair. Hence Obs hysterectomy was performed. Patient recovered completely on post op day 11 and was discharged the same day. Gravid non scarred uterus can rarely rupture spontaneously during labour and can present with vague complaints which can be difficult to diagnose merely on the basis of clinical signs and symptoms.
Introduction: Hirschsprung disease is a developmental disorder characterized by absence of gangli... more Introduction: Hirschsprung disease is a developmental disorder characterized by absence of ganglia in the distal colon, resulting in a functional obstruction. Case Report: Here we are presenting a case report of Hirschsprung Disease in a viable age of fetus and sharing our experience in diagnosis and treatment of this rare entity. Conclusion: Hirschsprung disease is diagnosed in the newborn period, but this rare entity is detectable at early stage with routine ultrasound investigations.
Indian Journal of Obstetrics and Gynecology Research, Dec 15, 2018
Craniosynostosis is a condition of one or more of the fibrous sutures in an infant skull prematur... more Craniosynostosis is a condition of one or more of the fibrous sutures in an infant skull prematurely fuses by turning into bone (ossification). 1 Premature fusion of cranial sutures may have an effect on cranial shape an less frequently on brain growth. 2 There is a changing in the growth pattern of the skull and the skull can't expand perpendicular to the fused suture, craniosynostosis can lead to abnormal head shape and abnormal facial features and results in increased intracranial pressure leading possibly to visual difficulty, sleeping impairment, eating problem, or impaired mental status with a significant reduction in IQ.
Indian Journal of Obstetrics and Gynecology Research, 2017
Introduction: Ferric Carboxymaltose (FCM), a dextran free iron formulation can be administered in... more Introduction: Ferric Carboxymaltose (FCM), a dextran free iron formulation can be administered in large doses without the risk of severe anaphylactic reactions in postpartum anemia (PPA). Evidence suggest that FCM is highly effective in correcting anemia and restoring iron stores faster. Aims & Objective: To gather real-world clinical practice events on safety and efficacy of FCM injection in Indian patients with PPA. Materials and Methods: This was a prospective, observational, non-comparative, non-interventional, prescription event monitoring study. Data were collected from 535 postpartum iron deficiency anemia patients treated with FCM injection. Safety was assessed from adverse events reported within 1 week post FCM administration. Treatment efficacy was assessed by change in Hb from baseline, at 1 week after treatment. Results: There were no serious adverse events (AE) reported. Only 4 patients (<1%) reported AE (mild nausea, n=1; shivering, n=1; palpitation, n=1; pruritus a...
Indian Journal of Obstetrics and Gynecology Research, Aug 15, 2022
First trimester in pregnancy is majorly about "Organogenesis", formation and development of embry... more First trimester in pregnancy is majorly about "Organogenesis", formation and development of embryo, and then progression to fetus. Insult to the stages of this organogenesis leads to various anomalies; including malformations. Lack of nutrition, folate deficiency, genetic factors, teratogenic drugs or environmental exposure can lead to such malformed embryo/fetus. Viability of such fetus depends on the system affected, and the severity. Many fetus do not survive major defects, but some may reach to the stage of live births, causing major problems for survival, growth and development. The psychological impact on the couple, along with future financial strain on possible treatments are additional burdens. There have been few investigations, now made available for diagnosing many of such malformations in earlier stages of pregnancy; making us able to detect them, so that with proper counselling of the couple and possible outcome, we can take decisions on continuation or termination of pregnancy. This was a prospective study, where we studied 200 newborns who were born with congenital malformations, during time period of January 2017 to December 2019. There were total 15687 deliveries in the said time period, making the incidence of congenital malformations to be 1.27%. Most commonly involved system was central nervous system (39%), followed by musculoskeletal system (25%), followed by gastrointestinal system (11%). This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
Indian Journal of Obstetrics and Gynecology Research, May 15, 2023
Background: Anaemia during pregnancy is allied with maternal and foetal complications like increa... more Background: Anaemia during pregnancy is allied with maternal and foetal complications like increased risk of intrauterine growth retardation, prematurity, low birth weight, and maternal and infant mortality. The agent iron isomaltose 1000 (Fur-IV) combines iron and isomaltose 1000 for slow, controlled release to reduce the risk of free iron toxicity and provide flexibility and convenience for high dose administration. Iron isomaltoside has been shown to be effective in the treatment of IDA in many treatment groups compared to intravenous iron sucrose and FCM. Materials and Methods: It is a prospective interventional study which is conducted to observe an increase in hemoglobin levels in obstetric and gynecological department patients suffering from IDA in whom oral iron preparation was ineffective or in case of clinical need to supply iron rapidly via single infusion of iron isomaltoside 1000. Each patient in the study received 500 mg single intravenous infusion. After this, patient was followed up and haemogram was repeated after 15 and 30 days of infusion while investigation for serum ferritin and serum iron was repeated after 30 days. Results: Average Hb concentration in increased by 30.86% to 9.88 g/dL after 30 days of infusion. There is statistically significant difference between baseline values and post infusion 30 days values for serum ferritin and serum iron (p-value <0.0001 for both). Conclusion: IV iron isomaltoside administration was well tolerated in patients with gynecological IDA who were intolerant or unresponsive to oral iron therapy or who required rapid iron administration. This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
Indian Journal of Obstetrics and Gynecology Research, Dec 15, 2020
Craniosynostosis is a condition of one or more of the fibrous sutures in an infant skull prematur... more Craniosynostosis is a condition of one or more of the fibrous sutures in an infant skull prematurely fuses by turning into bone (ossification). 1 Premature fusion of cranial sutures may have an effect on cranial shape an less frequently on brain growth. 2 There is a changing in the growth pattern of the skull and the skull can't expand perpendicular to the fused suture, craniosynostosis can lead to abnormal head shape and abnormal facial features and results in increased intracranial pressure leading possibly to visual difficulty, sleeping impairment, eating problem, or impaired mental status with a significant reduction in IQ.
Indian Journal of Obstetrics and Gynecology Research, Jun 15, 2021
Background: One of the most frequent causes of neonatal mortality or NICU admission of neonates e... more Background: One of the most frequent causes of neonatal mortality or NICU admission of neonates especially in premature infants is Neonatal Respiratory Distress Syndrome (NRDS). Antenatal steroids are the most important and widely utilized interventions for improvement of neonatal outcomes like reducing incidence of respiratory distress syndrome (RDS), reducing neonatal NICU (neonatal intensive care unit) admission rates and also improve outcomes of pre-term infants. Antenatal steroids (ANS) like betamethasone 12 mg are given at 24 hourly IM at 28-34 weeks of gestation to mother. For administration of corticosteroids at less than 24 weeks of gestational age decision should be made at a senior level by taking all clinical aspects into consideration. Objective: To observe the effect of Betamethasone administration IM in pregnant women at risk of preterm delivery and fetal outcomes in terms of development of Respiratory Distress Syndrome (RDS) and Neonatal Intensive Care Unit (NICU) admission rate by giving it between 28 to 34 weeks of gestation. Introduction: Antenatal corticosteroids (betamethasone) play an important role for prevention of respiratory distress syndrome and reducing NICU admission rate of new borns and also reduce neonatal mortality and morbidity but benefits related to the time between administration of corticosteroid and delivery needed to be explored. Benefits of the injection betamethasone administration IM 12 mg between 24 hours and seven days on pre-term delivery has been established. 1,2 Methods: This was prospective study conducted in private setup from November 2020 to March 2021 in Scientific Research Institute, Surendranagar, Gujarat, India. Study comprised of 100 women with single tone pregnancies (28-36 weeks gestational age) in age group of 19-33 years not in labour, but at risk for pre-term delivery based on fetal or maternal indications. These pregnant women were treated with two doses of 12 mg Betamethasone Intramuscularly apart of 24 hourly for maturation of fetal lungs. Conclusion: Antenatal corticosteroids like betamethasone have a significant benefit on neonatal outcome even if used after 34 weeks of pregnancy. This was given prophylactically to those who are known to have increased risk of pre-term labour. Antenatal steroid like betamethasone 12 mg IM is also of benefit to reduce neonatal respiratory distress syndrome (NRDS) and NICU admission rates by giving it at 28-34 weeks of gestational age.
Indian Journal of Obstetrics and Gynecology Research, Feb 15, 2022
Dextrocardia is a clinical condition in which heart is located on the right side of the chest cav... more Dextrocardia is a clinical condition in which heart is located on the right side of the chest cavity. Dextroversion is a result of early interruption of normal embryological development and therefore, rarely occurs without other cardiac and noncardiac anomalies. Isolated dextrocardia is a benign condition. It can often be associated with other congenital anomalies which can lead to failure to thrive, breathing difficulties, recurrent infections in new borns and neonates. It presents in situs solitus and situs inversus. Among them Dextrocardia with situs solitus is very rare. We are here presenting a case of dextrocardia with situs solitus. This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
Indian Journal of Obstetrics and Gynecology Research
To evaluate efficacy and safety of the FotonaSmooth device in treatment of SUI (stress urinary in... more To evaluate efficacy and safety of the FotonaSmooth device in treatment of SUI (stress urinary incontinence) patients after treating them with Er: YAG laser using both objective and patient-reported outcomes. Stress urinary incontinence (SUI) is a leakage of urine during moments of physical activity that increases abdominal pressure, such as coughing, sneezing, laughing, or exercise. It is most common seen health problem among women of certain age and it is most common type of urinary incontinence in women. Here, SUI is treated using intravaginal laser therapy by using non ablative Er: YAG (erbium-doped yttrium aluminium garnet) laser with SMOOTH mode technology.: The 96 parous women with SUI were treated according to IncontiLaseclinical treatmentprotocol by using non-ablative Er: YAG (erbium-doped yttrium aluminium garnet) laser with SMOOTH mode technology at Vcare laser centre state of art centre for cosmetic gynaecology, Indore, Madhya Pradesh. At baseline, at 2 months and at 9 m...
Indian Journal of Obstetrics and Gynecology Research, 2017
A 55 year old postmenopausal woman was brought to casualty department of C. U. Shah Medical Colle... more A 55 year old postmenopausal woman was brought to casualty department of C. U. Shah Medical College and Hospital with history of fall down with lower abdominal pain and vomiting. Patient having history of lower abdominal pain, non foul smelling whitish discharge, low grade on and off fever since 1 year associated with gradual weight loss since 2 years. Per abdominal examination reveals tender, distended with muscle rigidity. Exploratory laparotomy was performed under the diagnosis of perforation of GI tract with x-ray showing free gas under diaphragm. On exploration, the uterus was found to have fundal perforation of size 2x2 cm in dimension. With purulent material extruding from uterine cavity and abdominal cavity filled with purulrnt discharge around 1.5 litre. A Total abdominal hysterectomy with bilateral Salpingoophrectomy was performed uneventful and peritoneal cavity wash given with normal saline multiple times. Patient recovered completely without any complications and was di...
The Posterior Reversible Encephalopathy Syndrome is a neurological condition described on 1996, d... more The Posterior Reversible Encephalopathy Syndrome is a neurological condition described on 1996, developed in patients with complex systemic conditions, especially pregnant women with preeclampsia that at the same time presented neurological signs as seizures, headache, visual loss, and vomiting in addition to posterior brain edema, visible on neuroimaging and located in parietal and occipital lobes, that usually reverses completely. We present two clinical cases with PRES and eclampsia, antenatal and post-partum, both with seizure and confi rmed brain edema with Nuclear Magnetic Resonance. Both had a favorable evolution after the anticonvulsivant and anti-hypertensive therapy were done. We discuss the controversy over pathophysiolgical mechanisms, the new methods for diagnosis and management and the importance of multidisciplinary approach.
Indian Journal of Obstetrics and Gynecology Research, 2017
A 30 year old female, gravida 3, para 2 with two previous full term normal vaginal deliveries and... more A 30 year old female, gravida 3, para 2 with two previous full term normal vaginal deliveries and a history of 9 months of amenorrhea was referred to C. U. Shah Medical college and Hospital for severe anemia with complaints of lower abdominal pain and breathlessness. Abdomen was soft, non-tender and unduly enlarged. Fetal heard sounds were absent. Laparotomy was performed under diagnosis of uterine rupture. Uterus was found to have ruptured from the posterior wall and was beyond repair. Hence Obs hysterectomy was performed. Patient recovered completely on post op day 11 and was discharged the same day. Gravid non scarred uterus can rarely rupture spontaneously during labour and can present with vague complaints which can be difficult to diagnose merely on the basis of clinical signs and symptoms.
Introduction: Hirschsprung disease is a developmental disorder characterized by absence of gangli... more Introduction: Hirschsprung disease is a developmental disorder characterized by absence of ganglia in the distal colon, resulting in a functional obstruction. Case Report: Here we are presenting a case report of Hirschsprung Disease in a viable age of fetus and sharing our experience in diagnosis and treatment of this rare entity. Conclusion: Hirschsprung disease is diagnosed in the newborn period, but this rare entity is detectable at early stage with routine ultrasound investigations.
Indian Journal of Obstetrics and Gynecology Research, Dec 15, 2018
Craniosynostosis is a condition of one or more of the fibrous sutures in an infant skull prematur... more Craniosynostosis is a condition of one or more of the fibrous sutures in an infant skull prematurely fuses by turning into bone (ossification). 1 Premature fusion of cranial sutures may have an effect on cranial shape an less frequently on brain growth. 2 There is a changing in the growth pattern of the skull and the skull can't expand perpendicular to the fused suture, craniosynostosis can lead to abnormal head shape and abnormal facial features and results in increased intracranial pressure leading possibly to visual difficulty, sleeping impairment, eating problem, or impaired mental status with a significant reduction in IQ.
Indian Journal of Obstetrics and Gynecology Research, 2017
Introduction: Ferric Carboxymaltose (FCM), a dextran free iron formulation can be administered in... more Introduction: Ferric Carboxymaltose (FCM), a dextran free iron formulation can be administered in large doses without the risk of severe anaphylactic reactions in postpartum anemia (PPA). Evidence suggest that FCM is highly effective in correcting anemia and restoring iron stores faster. Aims & Objective: To gather real-world clinical practice events on safety and efficacy of FCM injection in Indian patients with PPA. Materials and Methods: This was a prospective, observational, non-comparative, non-interventional, prescription event monitoring study. Data were collected from 535 postpartum iron deficiency anemia patients treated with FCM injection. Safety was assessed from adverse events reported within 1 week post FCM administration. Treatment efficacy was assessed by change in Hb from baseline, at 1 week after treatment. Results: There were no serious adverse events (AE) reported. Only 4 patients (<1%) reported AE (mild nausea, n=1; shivering, n=1; palpitation, n=1; pruritus a...
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