To evaluate the effect of the type of skin incision for Caesarean Section on the incision-deliver... more To evaluate the effect of the type of skin incision for Caesarean Section on the incision-delivery interval, and fetomaternal outcome. : A quasi-experimental study with convenient sampling involving two groups of women who underwent primary lower segment transverse caesarean section. Standard surgical techniques were used in both groups except the technique of skin incision : subumbilical midline or Pfannenstiel. A comparison of the two groups were made with regard to incision delivery interval, duration of surgery, day of oral intake, day of ambulation, duration of hospital stay, wound infection and estimated blood loss. Data was managed using SPSS software. Chi-Square test and Student t-test were used for analysis. P value was placed at P 0.05. : 200 women were studied (96 allocated to subumbilical midline and 1O4 to Pfannenstiel group). There were no significant differences between both groups in terms of incision delivery interval and duration of surgery. Those with Pfannenstiel incision were significantly associated with early oral intake, early ambulation , shorter duration of hospital stay and reduced risk of wound infection (P=0.
To evaluate the effect of two techniques of uterine incision expansion at caesarean section on th... more To evaluate the effect of two techniques of uterine incision expansion at caesarean section on the maternal blood loss, inadvertent extension of incisions and the feto-maternal outcome. A quasi-experimental study with convenient sampling involving two groups of women who underwent lower segment transverse caesarean section. Both groups were studied for their demographic characteristics and clinical data. Standard surgical techniques were used in both groups except the technique of uterine incision either by blunt or sharp method. Finally a comparison of the two groups was made regarding blood loss, changes in haemotocrit, blood transfusion and uterine tears. The study was conducted at the obstetric unit of Obafemi
Introduction: The impact of previous pregnancy outcome on future fertility in Nigeria has not bee... more Introduction: The impact of previous pregnancy outcome on future fertility in Nigeria has not been appreciated, hence the continued neglect of the adoption of safe motherhood measures in this sub-region. The objective of this study was to compare the past pregnancy outcomes among fertile and infertile patients in a Nigerian population. Methods: An institutional-based comparative case-controlled study of past pregnancy outcomes among infertile and fertile women was conducted. The data was managed using Epi-Info and the Statistical Package for Social Sciences. Results: 708 patients consisting of 472 pregnant women (fertile) and 236 infertile women were investigated. Infertile women were at a significant risk of having an adverse pregnancy outcome, such as induced abortion (p-value is 0.0001), postabortal sepsis (p-value is 0.0001), postpartum infection (p-value is 0.001), manual removal of the placenta (p-value is 0.0005) and prolonged unsupervised labour (p-value 0.0001), compared to pregnant fertile women. Logistic regression analysis of variables at 95 percent confidence intervals showed that the adjusted odds ratio for prolonged labour, prolonged rupture of membranes, postabortal sepsis and postpartum infection still remained significant. Conclusion: Previous mismanaged pregnancies impacted negatively on future fertility. Efforts should be directed towards the prevention of unplanned pregnancies. Motherhood must be made safer in planned pregnancies by prevention of complications, and aggressive and prompt treatment of any complication if and when it occurs.
International journal of gynaecology and obstetrics, Oct 1, 2012
been reported to be associated with invasive growth in malignant tumors. 2. Moesin was found to b... more been reported to be associated with invasive growth in malignant tumors. 2. Moesin was found to be expressed in 64% of cases of adenomysis but in only 34% of specimens of normal endometrium (p < 0.03). 3. Moesin was found to be expressed more strongly in stromal cells of adenomysis than in endometrial gland cells. 4. The invasive nature of OMC-9 was examined before and after transfection with Moesin siRNA, and was found to be significantly suppressed by the siRNA treatment (p < 0.01). Conclusions: The present findings demonstrate that Moesin is characteristically overexpressed in stromal cells of adenomyosis and functionally associated with its invasive growth. Management of Moesin expression may provide a new therapeutic approach for suppressing the progression of adenomyosis.
... nda kad›nlar›n üretim sa¤l›¤›nda karars›z ve etki alt›nda olmalar›d›r. Bu çal›flman›n amac› e... more ... nda kad›nlar›n üretim sa¤l›¤›nda karars›z ve etki alt›nda olmalar›d›r. Bu çal›flman›n amac› elefltirel bir yaklafl›mla erkeklerin gebelikte bak›ma kat›l›m› ve bu konuda karar alma rolü, gebelikte acil durum göstergelerine duyarl›l›klar›, sezgi ve davran›fllar›n› de¤erlendirmektir. ...
Background The Bluebelle Wound Healing Questionnaire (WHQ) is a universal-reporter outcome measur... more Background The Bluebelle Wound Healing Questionnaire (WHQ) is a universal-reporter outcome measure developed in the UK for remote detection of surgical-site infection after abdominal surgery. This study aimed to explore cross-cultural equivalence, acceptability, and content validity of the WHQ for use across low- and middle-income countries, and to make recommendations for its adaptation. Methods This was a mixed-methods study within a trial (SWAT) embedded in an international randomized trial, conducted according to best practice guidelines, and co-produced with community and patient partners (TALON-1). Structured interviews and focus groups were used to gather data regarding cross-cultural, cross-contextual equivalence of the individual items and scale, and conduct a translatability assessment. Translation was completed into five languages in accordance with Mapi recommendations. Next, data from a prospective cohort (SWAT) were interpreted using Rasch analysis to explore scaling a...
International Journal Of Community Medicine And Public Health
Background: The post-partum period presents a risk in unwanted/unplanned conception and often fru... more Background: The post-partum period presents a risk in unwanted/unplanned conception and often frustrating desire for contraceptive. This study aimed to determine the factors enhancing resumption of sexual intercourse, contraceptive usage and barriers to timely uptake of family planning methods.Methods: This cross-sectional study was conducted among 340 women within 3 to 16 weeks postpartum. Structured questionnaires adopted from similar studies were administered within three months. Statistical analysis was performed using the statistical package for the social sciences (SPSS) version 21.Results: 62.6% (213) of women resumed sexual activity with a mean time of 11.37 weeks±8.85 postpartum. More than one-third 37.6% (80) did so within puerperium and husbands in 78.4% (167) initiated sex. About 50% (107) were on modern contraceptives, whereas only 39.3% (42) were on contraception before their first postpartum sexual experience.Conclusions: There was high rate of resumption of sexual in...
Journal of Health, Population, and Nutrition, 2007
This paper reports the findings at baseline in a multi-phase project that aimed at reducing mater... more This paper reports the findings at baseline in a multi-phase project that aimed at reducing maternal mortality in a local government area (LGA) of South-West Nigeria. The objectives were to determine the availability of essential obstetric care (EOC) services in the LGA and to assess the quality of existing services. The first phase of this interventional study, which is the focus of this paper, consisted of a baseline health facility and needs assessment survey using instruments adapted from the United Nations guidelines. Twenty-one of 26 health facilities surveyed were public facilities, and five were privately owned. None of the facilities met the criteria for a basic EOC facility, while only one private facility met the criteria for a comprehensive EOC facility. Three facilities employed a nurse and/or a midwife, while unskilled health attendants manned 46% of the facilities. No health worker in the LGA had ever been trained in lifesaving skills. There was a widespread lack of b...
Background: There is no consensus on the preferred time to remove urethral catheter post caesarea... more Background: There is no consensus on the preferred time to remove urethral catheter post caesarean section. Aim: To compare rate of significant bacteriuria and urinary retention following 8-h (study) and 24-h urethral catheter removal (control) post elective caesarean section. Methods: A randomized controlled trial of eligible participants that underwent elective caesarean section under spinal anaesthesia between March 2019 and November 2019 was conducted. Participants (150 in each arm) were randomly assigned (1:1 ratio) to either 8-h or 24-h group. Primary outcome measures included rates of significant bacteriuria 48-h post-operatively and acute urine retention 6-h post urethral catheter removal. Analysis was by Intention-to-treat. ( www.pactr.org:PACTR202105874744483 ) Results: There were 150 participants randomized into each arm and data collection was complete. Significant bacteriuria was less in 8-h group (3% versus 6.0%; risk ratio (RR): 0.85 CI: 0.60 to 5.66; p = 0.274), thou...
International Journal of Gynecology & Obstetrics, 2020
ObjectiveTo review what is known about COVID‐19 and highlight gaps in the context of Nigerian obs... more ObjectiveTo review what is known about COVID‐19 and highlight gaps in the context of Nigerian obstetric practice. Research data on COVID‐19 are understandably sparse in Africa. Nigeria, like most African countries, is battling a disease she is poorly equipped to fight.MethodsThe current available literature on COVID‐19 was reviewed in relation to obstetric practice in the Nigerian context, gaps were identified, and recommendations were made to improve the handling of the COVID‐19 pandemic in Nigerian obstetric practice.ResultsIn and out of hospital, both the obstetrician and the obstetric patient are constantly being put at risk of exposure to the coronavirus because testing and preventive measures are either ineffective or non‐existent.ConclusionThe pandemic has exposed the gross inadequacies in Nigeria’s healthcare system and is therefore a wake‐up call to the need for a complete overhaul of infrastructure and services. The government will do well to increase the budget allocation...
To evaluate the effect of the type of skin incision for Caesarean Section on the incision-deliver... more To evaluate the effect of the type of skin incision for Caesarean Section on the incision-delivery interval, and fetomaternal outcome. : A quasi-experimental study with convenient sampling involving two groups of women who underwent primary lower segment transverse caesarean section. Standard surgical techniques were used in both groups except the technique of skin incision : subumbilical midline or Pfannenstiel. A comparison of the two groups were made with regard to incision delivery interval, duration of surgery, day of oral intake, day of ambulation, duration of hospital stay, wound infection and estimated blood loss. Data was managed using SPSS software. Chi-Square test and Student t-test were used for analysis. P value was placed at P 0.05. : 200 women were studied (96 allocated to subumbilical midline and 1O4 to Pfannenstiel group). There were no significant differences between both groups in terms of incision delivery interval and duration of surgery. Those with Pfannenstiel incision were significantly associated with early oral intake, early ambulation , shorter duration of hospital stay and reduced risk of wound infection (P=0.
To evaluate the effect of two techniques of uterine incision expansion at caesarean section on th... more To evaluate the effect of two techniques of uterine incision expansion at caesarean section on the maternal blood loss, inadvertent extension of incisions and the feto-maternal outcome. A quasi-experimental study with convenient sampling involving two groups of women who underwent lower segment transverse caesarean section. Both groups were studied for their demographic characteristics and clinical data. Standard surgical techniques were used in both groups except the technique of uterine incision either by blunt or sharp method. Finally a comparison of the two groups was made regarding blood loss, changes in haemotocrit, blood transfusion and uterine tears. The study was conducted at the obstetric unit of Obafemi
Introduction: The impact of previous pregnancy outcome on future fertility in Nigeria has not bee... more Introduction: The impact of previous pregnancy outcome on future fertility in Nigeria has not been appreciated, hence the continued neglect of the adoption of safe motherhood measures in this sub-region. The objective of this study was to compare the past pregnancy outcomes among fertile and infertile patients in a Nigerian population. Methods: An institutional-based comparative case-controlled study of past pregnancy outcomes among infertile and fertile women was conducted. The data was managed using Epi-Info and the Statistical Package for Social Sciences. Results: 708 patients consisting of 472 pregnant women (fertile) and 236 infertile women were investigated. Infertile women were at a significant risk of having an adverse pregnancy outcome, such as induced abortion (p-value is 0.0001), postabortal sepsis (p-value is 0.0001), postpartum infection (p-value is 0.001), manual removal of the placenta (p-value is 0.0005) and prolonged unsupervised labour (p-value 0.0001), compared to pregnant fertile women. Logistic regression analysis of variables at 95 percent confidence intervals showed that the adjusted odds ratio for prolonged labour, prolonged rupture of membranes, postabortal sepsis and postpartum infection still remained significant. Conclusion: Previous mismanaged pregnancies impacted negatively on future fertility. Efforts should be directed towards the prevention of unplanned pregnancies. Motherhood must be made safer in planned pregnancies by prevention of complications, and aggressive and prompt treatment of any complication if and when it occurs.
International journal of gynaecology and obstetrics, Oct 1, 2012
been reported to be associated with invasive growth in malignant tumors. 2. Moesin was found to b... more been reported to be associated with invasive growth in malignant tumors. 2. Moesin was found to be expressed in 64% of cases of adenomysis but in only 34% of specimens of normal endometrium (p < 0.03). 3. Moesin was found to be expressed more strongly in stromal cells of adenomysis than in endometrial gland cells. 4. The invasive nature of OMC-9 was examined before and after transfection with Moesin siRNA, and was found to be significantly suppressed by the siRNA treatment (p < 0.01). Conclusions: The present findings demonstrate that Moesin is characteristically overexpressed in stromal cells of adenomyosis and functionally associated with its invasive growth. Management of Moesin expression may provide a new therapeutic approach for suppressing the progression of adenomyosis.
... nda kad›nlar›n üretim sa¤l›¤›nda karars›z ve etki alt›nda olmalar›d›r. Bu çal›flman›n amac› e... more ... nda kad›nlar›n üretim sa¤l›¤›nda karars›z ve etki alt›nda olmalar›d›r. Bu çal›flman›n amac› elefltirel bir yaklafl›mla erkeklerin gebelikte bak›ma kat›l›m› ve bu konuda karar alma rolü, gebelikte acil durum göstergelerine duyarl›l›klar›, sezgi ve davran›fllar›n› de¤erlendirmektir. ...
Background The Bluebelle Wound Healing Questionnaire (WHQ) is a universal-reporter outcome measur... more Background The Bluebelle Wound Healing Questionnaire (WHQ) is a universal-reporter outcome measure developed in the UK for remote detection of surgical-site infection after abdominal surgery. This study aimed to explore cross-cultural equivalence, acceptability, and content validity of the WHQ for use across low- and middle-income countries, and to make recommendations for its adaptation. Methods This was a mixed-methods study within a trial (SWAT) embedded in an international randomized trial, conducted according to best practice guidelines, and co-produced with community and patient partners (TALON-1). Structured interviews and focus groups were used to gather data regarding cross-cultural, cross-contextual equivalence of the individual items and scale, and conduct a translatability assessment. Translation was completed into five languages in accordance with Mapi recommendations. Next, data from a prospective cohort (SWAT) were interpreted using Rasch analysis to explore scaling a...
International Journal Of Community Medicine And Public Health
Background: The post-partum period presents a risk in unwanted/unplanned conception and often fru... more Background: The post-partum period presents a risk in unwanted/unplanned conception and often frustrating desire for contraceptive. This study aimed to determine the factors enhancing resumption of sexual intercourse, contraceptive usage and barriers to timely uptake of family planning methods.Methods: This cross-sectional study was conducted among 340 women within 3 to 16 weeks postpartum. Structured questionnaires adopted from similar studies were administered within three months. Statistical analysis was performed using the statistical package for the social sciences (SPSS) version 21.Results: 62.6% (213) of women resumed sexual activity with a mean time of 11.37 weeks±8.85 postpartum. More than one-third 37.6% (80) did so within puerperium and husbands in 78.4% (167) initiated sex. About 50% (107) were on modern contraceptives, whereas only 39.3% (42) were on contraception before their first postpartum sexual experience.Conclusions: There was high rate of resumption of sexual in...
Journal of Health, Population, and Nutrition, 2007
This paper reports the findings at baseline in a multi-phase project that aimed at reducing mater... more This paper reports the findings at baseline in a multi-phase project that aimed at reducing maternal mortality in a local government area (LGA) of South-West Nigeria. The objectives were to determine the availability of essential obstetric care (EOC) services in the LGA and to assess the quality of existing services. The first phase of this interventional study, which is the focus of this paper, consisted of a baseline health facility and needs assessment survey using instruments adapted from the United Nations guidelines. Twenty-one of 26 health facilities surveyed were public facilities, and five were privately owned. None of the facilities met the criteria for a basic EOC facility, while only one private facility met the criteria for a comprehensive EOC facility. Three facilities employed a nurse and/or a midwife, while unskilled health attendants manned 46% of the facilities. No health worker in the LGA had ever been trained in lifesaving skills. There was a widespread lack of b...
Background: There is no consensus on the preferred time to remove urethral catheter post caesarea... more Background: There is no consensus on the preferred time to remove urethral catheter post caesarean section. Aim: To compare rate of significant bacteriuria and urinary retention following 8-h (study) and 24-h urethral catheter removal (control) post elective caesarean section. Methods: A randomized controlled trial of eligible participants that underwent elective caesarean section under spinal anaesthesia between March 2019 and November 2019 was conducted. Participants (150 in each arm) were randomly assigned (1:1 ratio) to either 8-h or 24-h group. Primary outcome measures included rates of significant bacteriuria 48-h post-operatively and acute urine retention 6-h post urethral catheter removal. Analysis was by Intention-to-treat. ( www.pactr.org:PACTR202105874744483 ) Results: There were 150 participants randomized into each arm and data collection was complete. Significant bacteriuria was less in 8-h group (3% versus 6.0%; risk ratio (RR): 0.85 CI: 0.60 to 5.66; p = 0.274), thou...
International Journal of Gynecology & Obstetrics, 2020
ObjectiveTo review what is known about COVID‐19 and highlight gaps in the context of Nigerian obs... more ObjectiveTo review what is known about COVID‐19 and highlight gaps in the context of Nigerian obstetric practice. Research data on COVID‐19 are understandably sparse in Africa. Nigeria, like most African countries, is battling a disease she is poorly equipped to fight.MethodsThe current available literature on COVID‐19 was reviewed in relation to obstetric practice in the Nigerian context, gaps were identified, and recommendations were made to improve the handling of the COVID‐19 pandemic in Nigerian obstetric practice.ResultsIn and out of hospital, both the obstetrician and the obstetric patient are constantly being put at risk of exposure to the coronavirus because testing and preventive measures are either ineffective or non‐existent.ConclusionThe pandemic has exposed the gross inadequacies in Nigeria’s healthcare system and is therefore a wake‐up call to the need for a complete overhaul of infrastructure and services. The government will do well to increase the budget allocation...
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Papers by ERNEST ORJI